A New Paradigm in Cellular Biology Gerson, Ling, Cope, Sodi
... and, most like free liquid water, although even this water is probably somewhat structured. The protein/lipid macromolecules are interwoven in a latticework that extends throughout the cell to form a skeleton‐like structure resembling a sponge. This skeleton itself controls ion concentrations by ...
... and, most like free liquid water, although even this water is probably somewhat structured. The protein/lipid macromolecules are interwoven in a latticework that extends throughout the cell to form a skeleton‐like structure resembling a sponge. This skeleton itself controls ion concentrations by ...
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... with the cell cycle, from the basal side (where DNA is synthesized) to the apical surface (where mitosis takes place); such nuclear movements were previously misinterpreted as the radial intercalation of cells. We further demonstrate that growth of epithelial girth between E12.5 and E14.5 is driven ...
... with the cell cycle, from the basal side (where DNA is synthesized) to the apical surface (where mitosis takes place); such nuclear movements were previously misinterpreted as the radial intercalation of cells. We further demonstrate that growth of epithelial girth between E12.5 and E14.5 is driven ...
Inducing Embryonic Stem Cells to Become
... Developmental and molecular studies have identified progenitor cells which give rise to cardiomyocytes in the developing heart. Proliferation of immature but contracting cardiomyocytes is a major contributor to the increase in cardiac mass observed during fetal development. The proliferative capacit ...
... Developmental and molecular studies have identified progenitor cells which give rise to cardiomyocytes in the developing heart. Proliferation of immature but contracting cardiomyocytes is a major contributor to the increase in cardiac mass observed during fetal development. The proliferative capacit ...
The Golgi Stack Reassembles during Telophase before Arrival of
... vesiculates at the onset of mitosis (Warren, 1993). The disassembly pathway involves the generation of several hundred Golgi clusters as a result of vesiculation (Lucocq et al., 1987) which subsequently shed thousands of vesicles into the mitotic cell cytoplasm (Lucocq et al., 1989). A random distri ...
... vesiculates at the onset of mitosis (Warren, 1993). The disassembly pathway involves the generation of several hundred Golgi clusters as a result of vesiculation (Lucocq et al., 1987) which subsequently shed thousands of vesicles into the mitotic cell cytoplasm (Lucocq et al., 1989). A random distri ...
How much territory can a single E. coli cell control?
... enclose a large enough volume of cytoplasm to present it with major transport problems. This review surveys E. coli cells much longer than those which grow in nature and in usual lab cultures. These include cells mutated in a single gene (metK) which are 2–4× longer than their non-mutated parent. Th ...
... enclose a large enough volume of cytoplasm to present it with major transport problems. This review surveys E. coli cells much longer than those which grow in nature and in usual lab cultures. These include cells mutated in a single gene (metK) which are 2–4× longer than their non-mutated parent. Th ...
Year 10 Biology GCSE Objectives
... I can measure a root hair cell observed using a light microscope. I can explain how temperature and concentration gradient affects rate of diffusion. I can write a hypothesis using detailed scientific knowledge and explain how it could be tested. ...
... I can measure a root hair cell observed using a light microscope. I can explain how temperature and concentration gradient affects rate of diffusion. I can write a hypothesis using detailed scientific knowledge and explain how it could be tested. ...
Glypican-1 Is a Vehicle for Polyamine Uptake in Mammalian Cells
... (HSPG). Potentially localizing to rafts and caveolae, they are selective regulators of ligand-receptor encounters and can thereby control both growth and development. The discoveries that mutations in genes involved in glypican assembly cause dysmorphic syndromes in man and aberrant patterning durin ...
... (HSPG). Potentially localizing to rafts and caveolae, they are selective regulators of ligand-receptor encounters and can thereby control both growth and development. The discoveries that mutations in genes involved in glypican assembly cause dysmorphic syndromes in man and aberrant patterning durin ...
IGF signaling directs ventricular cardiomyocyte
... Secreted factors from the epicardium are believed to be important in directing heart ventricular cardiomyocyte proliferation and morphogenesis, although the specific factors involved have not been identified or characterized adequately. We found that IGF2 is the most prominent mitogen made by primar ...
... Secreted factors from the epicardium are believed to be important in directing heart ventricular cardiomyocyte proliferation and morphogenesis, although the specific factors involved have not been identified or characterized adequately. We found that IGF2 is the most prominent mitogen made by primar ...
Cell shape and plasma membrane alterations after - An
... interaction between biological systems and MFs suggest that the primary site of interaction is the plasma membrane, whose structural and biophysical changes affect receptor binding or activation, and thereby affect cell function in general (Paradisi et al. 1993).The effects described for membrane re ...
... interaction between biological systems and MFs suggest that the primary site of interaction is the plasma membrane, whose structural and biophysical changes affect receptor binding or activation, and thereby affect cell function in general (Paradisi et al. 1993).The effects described for membrane re ...
Alteration of the Cytoplasmic Domain of the Membrane
... microchips (3 × 3 mm, Tecnomara Deutschland GmbH, FRG) was as described by Ash et al. (1977). This procedure was modified to facilitate the screening of a large number of clones by placing the antibody solution (5 ~tl) directly on top of the coverchip. Immunofluorescence of MDCK cells grown on filte ...
... microchips (3 × 3 mm, Tecnomara Deutschland GmbH, FRG) was as described by Ash et al. (1977). This procedure was modified to facilitate the screening of a large number of clones by placing the antibody solution (5 ~tl) directly on top of the coverchip. Immunofluorescence of MDCK cells grown on filte ...
Cytotoxic T Cells Sufficient to Induce Primary and Memory Soluble
... priming (11). The factors that empower the DC are unknown, but it is known that CD40 triggering can up-regulate costimulatory molecules and inflammatory cytokines such as IL-12 (22). The essential costimulatory requirements for generation of T cell memory are not defined. Although CD28-B7 interactio ...
... priming (11). The factors that empower the DC are unknown, but it is known that CD40 triggering can up-regulate costimulatory molecules and inflammatory cytokines such as IL-12 (22). The essential costimulatory requirements for generation of T cell memory are not defined. Although CD28-B7 interactio ...
Non-genetic heterogeneity of cells in development: more than just
... Attractor state. A stationary and stable network state into which a set of particular network states will eventually evolve (‘be attracted to’). This happens because the interactions between the network elements impose constraints so that the majority of theoretically possible network states is unst ...
... Attractor state. A stationary and stable network state into which a set of particular network states will eventually evolve (‘be attracted to’). This happens because the interactions between the network elements impose constraints so that the majority of theoretically possible network states is unst ...
Amino Acid Analogs, and Nucleases on the Synthesis of DNA in
... within a short time after contact with the cells in culture medium, caused an increase in the number of cells able to incorporate thymidine. After 3 hours of treatment both DNase II and RNase resulted in decreases in DNA synthesis. The results are discussed with regard to the hypothesis that RNA may ...
... within a short time after contact with the cells in culture medium, caused an increase in the number of cells able to incorporate thymidine. After 3 hours of treatment both DNase II and RNase resulted in decreases in DNA synthesis. The results are discussed with regard to the hypothesis that RNA may ...
Characterization and Expression of Monosaccharide Transporters
... Fujix BAS2000 Bio-Imaging Analyzer (Fuji Photo Film Co., Ltd., Tokyo, Japan). RNA extraction and Northern blot analysis RNA was extracted from leaf sheaths, leaf blades (growing and opened) and roots of 10-d-old plants, suspension calli and isolated dry embryos by using the aurin tricarboxylic acid ...
... Fujix BAS2000 Bio-Imaging Analyzer (Fuji Photo Film Co., Ltd., Tokyo, Japan). RNA extraction and Northern blot analysis RNA was extracted from leaf sheaths, leaf blades (growing and opened) and roots of 10-d-old plants, suspension calli and isolated dry embryos by using the aurin tricarboxylic acid ...
Bone marrow and stem cell transplantation
... are examined for any abnormality and then discarded. Blood vessels in the umbilical cord contain only blood from the baby because the mother's blood ...
... are examined for any abnormality and then discarded. Blood vessels in the umbilical cord contain only blood from the baby because the mother's blood ...
The septins: roles in cytokinesis and other processes Mark S
... C. albicans is morphologically similar and relatively close phylogenetically [23,24] to S. cerevisiae, and it is not yet clear whether septin function in other types of cells involves assembly into a higher-order structure such as the neck filaments. To date, no similar structures have been observed ...
... C. albicans is morphologically similar and relatively close phylogenetically [23,24] to S. cerevisiae, and it is not yet clear whether septin function in other types of cells involves assembly into a higher-order structure such as the neck filaments. To date, no similar structures have been observed ...
Two-photon laser scanning microscopy imaging of intact spinal cord and
... doi:10.1016/j.jim.2009.09.007 ...
... doi:10.1016/j.jim.2009.09.007 ...
Recruitment of lymphocytes to the human liver
... gut via the portal veins. This complex supply is necessary to allow nutrients from the gut to be transported to the liver, which is thus constantly exposed to gut-derived antigens in the portal blood. Because portal blood also presents a route through which infectious organisms can enter the liver, ...
... gut via the portal veins. This complex supply is necessary to allow nutrients from the gut to be transported to the liver, which is thus constantly exposed to gut-derived antigens in the portal blood. Because portal blood also presents a route through which infectious organisms can enter the liver, ...
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... using attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. Infrared spectra of aqueous model organic molecules, representatives of the common functional groups found in bacterial cell walls (i.e., hydroxyl, carboxyl, phosphoryl, and amide groups), were also examined in or ...
... using attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. Infrared spectra of aqueous model organic molecules, representatives of the common functional groups found in bacterial cell walls (i.e., hydroxyl, carboxyl, phosphoryl, and amide groups), were also examined in or ...
Mechanism of platelet dense granule biogenesis: study of cargo
... Platelets contribute to normal hemostasis by releasing their ␣ granule (AG) and dense granule (DG) components at sites of vascular injury. DGs concentrate small molecules such as serotonin, ADP, and calcium, and their involvement in hemostasis is evident in patients presenting with bleeding disorder ...
... Platelets contribute to normal hemostasis by releasing their ␣ granule (AG) and dense granule (DG) components at sites of vascular injury. DGs concentrate small molecules such as serotonin, ADP, and calcium, and their involvement in hemostasis is evident in patients presenting with bleeding disorder ...
Voltage-dependent Ionic Conductances of Type I Spiral Ganglion
... bottom. A modified Leibovitz medium (NaCl, 142.2 mM; KCl, 5.37 mM; CaCl,, 1.25 mM; MgCl,, 1.48 mM; HEPES, 5.0 mM; dextrose, 5.0 mM; pH 7.2) was used as the normal perfusate. Modifications to the extracellular medium are noted in figure captions, with NaCl adjusted to maintain osmolarity (300 mOsm). ...
... bottom. A modified Leibovitz medium (NaCl, 142.2 mM; KCl, 5.37 mM; CaCl,, 1.25 mM; MgCl,, 1.48 mM; HEPES, 5.0 mM; dextrose, 5.0 mM; pH 7.2) was used as the normal perfusate. Modifications to the extracellular medium are noted in figure captions, with NaCl adjusted to maintain osmolarity (300 mOsm). ...
Antigen-antibody complex stimulation of dendritic cells Oscar Díaz
... cells showed the characteristic phenotype and functional properties of immature DCs, such as their elevated antigen uptake capacity and high expression of CD1 and MHC class I and II molecules, as well as the stimulatory capacity of naïve T cells (Sallusto and Lanzavecchia, 1994). Nevertheless, the c ...
... cells showed the characteristic phenotype and functional properties of immature DCs, such as their elevated antigen uptake capacity and high expression of CD1 and MHC class I and II molecules, as well as the stimulatory capacity of naïve T cells (Sallusto and Lanzavecchia, 1994). Nevertheless, the c ...
Phloem loading and unloading - HAL
... plasmodesmata!. First, in some species, electron microscopy shows more or less numerous ptasmodesmata connecting the conducting complex with the surrounding cells (Van Bel, 1987). In addition, several authors have reported on particular cells (paraveinal mesophyll), which seem to be located in a str ...
... plasmodesmata!. First, in some species, electron microscopy shows more or less numerous ptasmodesmata connecting the conducting complex with the surrounding cells (Van Bel, 1987). In addition, several authors have reported on particular cells (paraveinal mesophyll), which seem to be located in a str ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.