ForC, a novel type of formin family protein lacking an FH1 domain, is
... domain (Evangelista et al., 1997; Holt and Koffer, 2001; Imamura et al., 1997; Wasserman, 1998; Watanabe et al., 1997). In addition, some formin proteins interact with the Src homology 3 (SH3) domain or WW domain through the FH1 domain (Holt and Koffer, 2001). The FH2 domain is a highly conserved re ...
... domain (Evangelista et al., 1997; Holt and Koffer, 2001; Imamura et al., 1997; Wasserman, 1998; Watanabe et al., 1997). In addition, some formin proteins interact with the Src homology 3 (SH3) domain or WW domain through the FH1 domain (Holt and Koffer, 2001). The FH2 domain is a highly conserved re ...
Cell wall synthesis is necessary for membrane dynamics during
... (green) signals at different stages of engulfment corresponding to wild-type (left) and spoIID(D210A) (right) images. ...
... (green) signals at different stages of engulfment corresponding to wild-type (left) and spoIID(D210A) (right) images. ...
Mechanism of Uptake and Retrograde Axonal Transport of
... types of membrane during exocytotic transmitter release, vesicle membrane seems to be retrieved selectively (25, 26, 38, 67). Less clear is the origin of synaptic vesicles. Vesicles, especially large dense-core vesicles in adrenergic or serotoninergic neurons, are rapidly transported from the cell b ...
... types of membrane during exocytotic transmitter release, vesicle membrane seems to be retrieved selectively (25, 26, 38, 67). Less clear is the origin of synaptic vesicles. Vesicles, especially large dense-core vesicles in adrenergic or serotoninergic neurons, are rapidly transported from the cell b ...
Specification of the C. elegans MS blastomere by the T
... figure (Mello et al., 1992). The table summarizing the major embryonic cell types made by descendants of AB, MS, D and C was adapted from lineage data (Sulston et al., 1983). In embryo diagrams, anterior is towards the left, and dorsal is upwards. ...
... figure (Mello et al., 1992). The table summarizing the major embryonic cell types made by descendants of AB, MS, D and C was adapted from lineage data (Sulston et al., 1983). In embryo diagrams, anterior is towards the left, and dorsal is upwards. ...
Balancing mitochondrial biogenesis and
... mitochondria. Emerging evidence indicates that coordination between mitochondrial biogenesis and mitophagy is essential for proper mitochondrial homeostasis. Several molecules have been implicated in the fine-tuning of coordination. Sirtuins modulate energy metabolism and longevity through their fun ...
... mitochondria. Emerging evidence indicates that coordination between mitochondrial biogenesis and mitophagy is essential for proper mitochondrial homeostasis. Several molecules have been implicated in the fine-tuning of coordination. Sirtuins modulate energy metabolism and longevity through their fun ...
c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a
... known functions of these 172 genes were particularly related to neuronal growth and regeneration (Figure 1C). We selected 32 of the 172 disregulated genes for further analysis by RT-QPCR. In every case this confirmed the disregulation shown by the microarray data (Figures 1D–1F and Table S3). Six of ...
... known functions of these 172 genes were particularly related to neuronal growth and regeneration (Figure 1C). We selected 32 of the 172 disregulated genes for further analysis by RT-QPCR. In every case this confirmed the disregulation shown by the microarray data (Figures 1D–1F and Table S3). Six of ...
We have found that an H3K27 methyltransferase activity co
... would be important to clarify that Ezh2 regulation by NIPP1 is a direct event rather than an indirect one. The fact that NIPP1 and eed, a Ezh2 partner in PRC2,3,4 complexes and needed for their H3K27me3 activity, would support such a direct role. However, it is not possible to ensure that all eed is ...
... would be important to clarify that Ezh2 regulation by NIPP1 is a direct event rather than an indirect one. The fact that NIPP1 and eed, a Ezh2 partner in PRC2,3,4 complexes and needed for their H3K27me3 activity, would support such a direct role. However, it is not possible to ensure that all eed is ...
Leukaemia Section Anaplasic large cell lymphoma (ALCL) Atlas of Genetics and Cytogenetics
... The 2 first categories are defined according to the involvement (or not) of ALK in fusion proteins with various partners (see below); ALK+ ALCL cases are sometimes called ALK lymphomas, or ALKomas. ALK+ ALCL can be further divided into t(2;5) cases, with NPM1-ALK fusion protein which localises both ...
... The 2 first categories are defined according to the involvement (or not) of ALK in fusion proteins with various partners (see below); ALK+ ALCL cases are sometimes called ALK lymphomas, or ALKomas. ALK+ ALCL can be further divided into t(2;5) cases, with NPM1-ALK fusion protein which localises both ...
Here - New Mexico State University
... Development of complex multicellular organisms requires careful regulation at the transcriptional as well as post-transcriptional levels. Post-transcriptional gene regulation is in part mediated by a class of 21-25 nucleotides long non-coding RNAs known as microRNAs (miRNAs). While we have made grea ...
... Development of complex multicellular organisms requires careful regulation at the transcriptional as well as post-transcriptional levels. Post-transcriptional gene regulation is in part mediated by a class of 21-25 nucleotides long non-coding RNAs known as microRNAs (miRNAs). While we have made grea ...
Lessons on longevity from budding yeast
... to extend CLS6. Transferring cells to water, rather than allowing them to age in expired medium, has also been shown to increase CLS, demonstrating that extracellular factors limit CLS9. Transferring post-mitotic yeast to water containing physiologically relevant concentrations of acetic acid, but n ...
... to extend CLS6. Transferring cells to water, rather than allowing them to age in expired medium, has also been shown to increase CLS, demonstrating that extracellular factors limit CLS9. Transferring post-mitotic yeast to water containing physiologically relevant concentrations of acetic acid, but n ...
Arabidopsis thaliana mitogen-activated protein kinase 6 is involved
... apply the above equation for estimation of average cell-cycle time in the PD. Criteria for defining the PD and TD have been described (Ivanov and Dubrovsky, 2013). Briefly, the PD comprises cells that maintain proliferation activity and the TD comprises cells that have very low probability of cell p ...
... apply the above equation for estimation of average cell-cycle time in the PD. Criteria for defining the PD and TD have been described (Ivanov and Dubrovsky, 2013). Briefly, the PD comprises cells that maintain proliferation activity and the TD comprises cells that have very low probability of cell p ...
Intermetallic Catalysts: An Efficient Approach for the Reduction in the
... The goal of this proposal is to develop the electrode materials containing less- and/or non PGM for fuel cells. The anode and/or cathode catalysts containing less PGM can be achieved by synthesizing of intermetallic phase of PGM with d- and f- block elements. This is because, the ever synthesized PG ...
... The goal of this proposal is to develop the electrode materials containing less- and/or non PGM for fuel cells. The anode and/or cathode catalysts containing less PGM can be achieved by synthesizing of intermetallic phase of PGM with d- and f- block elements. This is because, the ever synthesized PG ...
Suppressor analysis of the protein kinase Elm1p, an enzyme
... occur is defined by external nutritive and genetically programmed intrinsic factors. Filamentous form growth in 5. cerevisiae also results in the alteration of bud-site selection. Invasive growth of haploid cells results in a change in the bud-site selection from an axial to a bipolar pattern (116). ...
... occur is defined by external nutritive and genetically programmed intrinsic factors. Filamentous form growth in 5. cerevisiae also results in the alteration of bud-site selection. Invasive growth of haploid cells results in a change in the bud-site selection from an axial to a bipolar pattern (116). ...
118 - University of Oxford
... have also demonstrated that transplantation of a portion of the PMZ into the LMZ of a host embryo induces a second primitive streak to grow at 90◦ to the primitive streak growing from the PMZ. • Any part of the blastoderm, provided it contains a portion of the PMZ and is suf£ciently large, has the p ...
... have also demonstrated that transplantation of a portion of the PMZ into the LMZ of a host embryo induces a second primitive streak to grow at 90◦ to the primitive streak growing from the PMZ. • Any part of the blastoderm, provided it contains a portion of the PMZ and is suf£ciently large, has the p ...
Insights into Chromatin Structure and Dynamics in Plants
... histones containing two copies of each of the four core histones (H2A, H2B, H3 and H4) forming the most fundamental unit of chromatin²the nucleosome [1]. Core histones have been structurally conserved through evolution and have evolved to accomplish two conflicting and yet vital tasks: on one hand t ...
... histones containing two copies of each of the four core histones (H2A, H2B, H3 and H4) forming the most fundamental unit of chromatin²the nucleosome [1]. Core histones have been structurally conserved through evolution and have evolved to accomplish two conflicting and yet vital tasks: on one hand t ...
AN ELECTRON-MICROSCOPE STUDY OF NATURALLY
... usually bent and segmented as if composed of shorter units. Thickness was variable, but in general was about 30% less than that of pili a and some micrographs (fig. 2b) showed these fibrils as a continuation of normal pili. Because it is not yet clear whether they are structurally related to pili a ...
... usually bent and segmented as if composed of shorter units. Thickness was variable, but in general was about 30% less than that of pili a and some micrographs (fig. 2b) showed these fibrils as a continuation of normal pili. Because it is not yet clear whether they are structurally related to pili a ...
Transcription-associated recombination in eukaryotes: link between
... DSBs are produced endogenously by various sources including topoisomerases or exogenously by sources like ionizing radiation and chemicals that generate reactive oxygen species [reviewed in (10)]. DSBs also normally occur during V(D)J recombination and immunoglobulin class-switching processes and al ...
... DSBs are produced endogenously by various sources including topoisomerases or exogenously by sources like ionizing radiation and chemicals that generate reactive oxygen species [reviewed in (10)]. DSBs also normally occur during V(D)J recombination and immunoglobulin class-switching processes and al ...
Spatial and temporal regulation of DNA
... Durzan, 1996) suggest that, as in animal systems, apoptosis may also play an important role in plants. In a previous paper it was shown that both a-amylase production and DNA fragmentation are activated over the aleurone in a spatial-temporal way ( Wang et al., 1996a). The activity of both processes ...
... Durzan, 1996) suggest that, as in animal systems, apoptosis may also play an important role in plants. In a previous paper it was shown that both a-amylase production and DNA fragmentation are activated over the aleurone in a spatial-temporal way ( Wang et al., 1996a). The activity of both processes ...
The role of active oxygen species in plant signal transduction
... planta. By using antisense and sense technology, transgenic Nicotiana tabacum lines (CAT1AS) were produced that retained only 10% of their residual catalase activity [27]. These transgenic plants were used to study the local and systemic signaling role of H2O2 in pathogen defense. Catalases are tetr ...
... planta. By using antisense and sense technology, transgenic Nicotiana tabacum lines (CAT1AS) were produced that retained only 10% of their residual catalase activity [27]. These transgenic plants were used to study the local and systemic signaling role of H2O2 in pathogen defense. Catalases are tetr ...
System approaches to study root hairs as a single cell plant model
... they serve as a model to study this distinctive growth process (Campanoni and Blatt, 2007). However, in legumes, root hairs are also the primary site for rhizobial infection and, therefore, several studies have sought to define the early events in this infection process. Libault et al. (2010b) studi ...
... they serve as a model to study this distinctive growth process (Campanoni and Blatt, 2007). However, in legumes, root hairs are also the primary site for rhizobial infection and, therefore, several studies have sought to define the early events in this infection process. Libault et al. (2010b) studi ...
RNA polymerase III component Rpc9 regulates
... adult hematopoiesis from 4 days post fertilization (dpf ) (Paik and Zon, 2010). The balance among self-renewal, proliferation and differentiation is essential for HSPC maintenance in these specialized niches that are delicately orchestrated by cell intrinsic networks and environment cues (Mendelson ...
... adult hematopoiesis from 4 days post fertilization (dpf ) (Paik and Zon, 2010). The balance among self-renewal, proliferation and differentiation is essential for HSPC maintenance in these specialized niches that are delicately orchestrated by cell intrinsic networks and environment cues (Mendelson ...
The Pathogenic Fungus Paracoccidioides brasiliensis Exports
... natants were concentrated 20-fold using an Amicon ultrafiltration system (100kDa cutoff). Concentrated supernatants containing high-molecular-weight components were centrifuged at 15,000 ⫻ g (30 min) to remove aggregates, and the resulting supernatant was then ultracentrifuged at 100,000 ⫻ g for 1 h ...
... natants were concentrated 20-fold using an Amicon ultrafiltration system (100kDa cutoff). Concentrated supernatants containing high-molecular-weight components were centrifuged at 15,000 ⫻ g (30 min) to remove aggregates, and the resulting supernatant was then ultracentrifuged at 100,000 ⫻ g for 1 h ...
Nature Cell Biol. 6
... LPA-treated Swiss 3T3 fibroblasts (data not shown). Prolonged incubation of serum-starved and amino-acid-starved NIH or Swiss 3T3 cells with amino acids (1–8 h) induced a low level of stress-fibre formation that was also rapamycin insensitive (data not shown). Thus, as shown previously for serum and ...
... LPA-treated Swiss 3T3 fibroblasts (data not shown). Prolonged incubation of serum-starved and amino-acid-starved NIH or Swiss 3T3 cells with amino acids (1–8 h) induced a low level of stress-fibre formation that was also rapamycin insensitive (data not shown). Thus, as shown previously for serum and ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.