Yeasts as a model for human diseases
... elephant’ – demonstrating that molecular details of functional pathways were conserved from one organism to another was neither frequently nor easily done, especially for species as remotely related as yeast and humans. The fact that a human gene was able to complement a yeast mutant defective in th ...
... elephant’ – demonstrating that molecular details of functional pathways were conserved from one organism to another was neither frequently nor easily done, especially for species as remotely related as yeast and humans. The fact that a human gene was able to complement a yeast mutant defective in th ...
Full Text
... specification of border derivatives. Msx1 is a direct mediator of BMP signalling and as such functions in promoting epidermal and repressing neural character during early stages of Xenopus development, thereby positioning the border between both tissues (Suzuki, et al., 1997; Feledy, et al., 1999; P ...
... specification of border derivatives. Msx1 is a direct mediator of BMP signalling and as such functions in promoting epidermal and repressing neural character during early stages of Xenopus development, thereby positioning the border between both tissues (Suzuki, et al., 1997; Feledy, et al., 1999; P ...
Antisense phenotypes reveal a role for SHY, a pollen
... transformation. We reasoned that it was unlikely that AS expression of the SHY LRR domain would inhibit other pollen-expressed LRR proteins because Southern analysis (Figure 1a) showed that the SHY-LRR probe hybridized only with the SHY sequence. Forty-five primary transformants (T0) were recovered ...
... transformation. We reasoned that it was unlikely that AS expression of the SHY LRR domain would inhibit other pollen-expressed LRR proteins because Southern analysis (Figure 1a) showed that the SHY-LRR probe hybridized only with the SHY sequence. Forty-five primary transformants (T0) were recovered ...
Recombinant Cellulase and Cellulosome Systems
... sequential hydrolysis and fermentation (SHF). It requires the addition of costly cellulase cocktails separately produced by fungi, and accumulation of glucose during the hydrolysis step leads to end product inhibition. The capital cost of having multiple separate steps, and the time required for seq ...
... sequential hydrolysis and fermentation (SHF). It requires the addition of costly cellulase cocktails separately produced by fungi, and accumulation of glucose during the hydrolysis step leads to end product inhibition. The capital cost of having multiple separate steps, and the time required for seq ...
Construction of the yeast whole-cell Rhizopus oryzae lipase
... variations in all 1 098 nucleotides, resulting in 178 changes out of 366 codons. Further study demonstrated that the overall G+C content of codonoptimized pro-ROL sequence was reduced to 41.53% from 46.81% of the non-optimized sequence. 3.2 Expression of the recombinant gene A clear halo was observe ...
... variations in all 1 098 nucleotides, resulting in 178 changes out of 366 codons. Further study demonstrated that the overall G+C content of codonoptimized pro-ROL sequence was reduced to 41.53% from 46.81% of the non-optimized sequence. 3.2 Expression of the recombinant gene A clear halo was observe ...
Sarcolemmal cholesterol and caveolin-3 dependence of - AJP
... Foundation Research Centre, Griffith Univ., Gold Coast Campus, Parklands Drive, Parklands 4222, QLD, Australia (e-mail: [email protected]). http://www.ajpheart.org ...
... Foundation Research Centre, Griffith Univ., Gold Coast Campus, Parklands Drive, Parklands 4222, QLD, Australia (e-mail: [email protected]). http://www.ajpheart.org ...
Insulin-Like Growth Factor and Potassium Depolarization Maintain
... During development of the vertebrate nervous system, approximately half of the neurons that are generated die by a process called “programmed cell death.” This naturally occurring process is mediated by apoptosis, a specific form of programmed cell death that has characteristic morphological and bio ...
... During development of the vertebrate nervous system, approximately half of the neurons that are generated die by a process called “programmed cell death.” This naturally occurring process is mediated by apoptosis, a specific form of programmed cell death that has characteristic morphological and bio ...
Chloroplast structure: from chlorophyll granules to supra
... large protruding particles that exhibit two sub-domains (arrowheads). A small number of similar particles are seen in the surrounding stroma membrane area (arrowheads). The large dimeric particles in the ESs region correspond to the lumenal domains of the dimeric PS II complexes that protrude into t ...
... large protruding particles that exhibit two sub-domains (arrowheads). A small number of similar particles are seen in the surrounding stroma membrane area (arrowheads). The large dimeric particles in the ESs region correspond to the lumenal domains of the dimeric PS II complexes that protrude into t ...
Microsporidia: Why Make Nucleotides if You Can Steal Them?
... Microsporidia and the recycling of nucleotides The continual turnover of RNA, which releases the nucleoside monophosphates, represents a major, ready-made source of nucleotides [27]. The enzymes needed to regenerate nucleoside triphosphates following nucleic acid degradation have been retained by mi ...
... Microsporidia and the recycling of nucleotides The continual turnover of RNA, which releases the nucleoside monophosphates, represents a major, ready-made source of nucleotides [27]. The enzymes needed to regenerate nucleoside triphosphates following nucleic acid degradation have been retained by mi ...
The Panicum mosaic virus-like 3` cap
... different sizes of rRNAs and scaffolding proteins) (30,55-57). It is equipped with three tRNA binding sites: A, P, and E (29,56). The ternary complex, composed of eIF2 bound to GTP and the initiator methioninebound tRNA interacts with the 40S ribosome bound to initiation factors eIF3, eIF1A, and eIF ...
... different sizes of rRNAs and scaffolding proteins) (30,55-57). It is equipped with three tRNA binding sites: A, P, and E (29,56). The ternary complex, composed of eIF2 bound to GTP and the initiator methioninebound tRNA interacts with the 40S ribosome bound to initiation factors eIF3, eIF1A, and eIF ...
The Brd gene family and the N pathway
... small protein that is distantly related to the product of the E(spl)m4 gene, a non-bHLH member of the E(spl)-C; both proteins include a predicted basic amphipathic α-helical domain (Klämbt et al., 1989; Leviten et al., 1997). The phenotype of Brd gain-of-function mutants, the observation that both B ...
... small protein that is distantly related to the product of the E(spl)m4 gene, a non-bHLH member of the E(spl)-C; both proteins include a predicted basic amphipathic α-helical domain (Klämbt et al., 1989; Leviten et al., 1997). The phenotype of Brd gain-of-function mutants, the observation that both B ...
Role of lipids in the translocation of proteins across membranes
... the ribosome and subsequently targets the ribosome nascent chain complex to the SRP receptor on the membrane. Some precursors, such as prepro-α-factor, however, follow a SRPindependent post-translational pathway. In this case, the energy needed to drive translocation is derived from ATP hydrolysis b ...
... the ribosome and subsequently targets the ribosome nascent chain complex to the SRP receptor on the membrane. Some precursors, such as prepro-α-factor, however, follow a SRPindependent post-translational pathway. In this case, the energy needed to drive translocation is derived from ATP hydrolysis b ...
Auxin and the Communication Between Plant Cells
... any photosynthetic activity has to be excluded from heterocysts. These cells are therefore hypocellular with respect to assimilation. The balance between nitrogen export and assimilate import has to be maintained although the total number of cells grows continuously. This balance is kept by iterativ ...
... any photosynthetic activity has to be excluded from heterocysts. These cells are therefore hypocellular with respect to assimilation. The balance between nitrogen export and assimilate import has to be maintained although the total number of cells grows continuously. This balance is kept by iterativ ...
... wild-type (A) and 35S::PID (B) embryos and in a globular-stage RPS5AdPID (C) embryo. The absence of basally located PIN1 in cells above the hypophyseal cell group (arrowhead) is indicative of the basal-to-apical shift in PIN1 polarity. (D and E) DR5rev::GFP expression in globular wild-type (D) and R ...
Craniofacial Development and the Evolution of the Vertebrates: the
... refers to the trabecula and its derivatives. (B) Neural-crestderived elements have been colored red, and the mesodermal elements blue, based on several, cell-labeling and molecular genetic experiments reported by Le Lièvre and Le Douarin (1975), Le Lièvre (1978), Noden (1984), Couly et al. (1993), a ...
... refers to the trabecula and its derivatives. (B) Neural-crestderived elements have been colored red, and the mesodermal elements blue, based on several, cell-labeling and molecular genetic experiments reported by Le Lièvre and Le Douarin (1975), Le Lièvre (1978), Noden (1984), Couly et al. (1993), a ...
Slide 1
... hereditary anemias called thalassemia • Some thalassemia patients were identified with no discernible mutations in the protein-coding part of the globin genes, nor in their promoters • It was found that some thalassemia cases were due to deletions that altered the LCR regions, causing abnormal expre ...
... hereditary anemias called thalassemia • Some thalassemia patients were identified with no discernible mutations in the protein-coding part of the globin genes, nor in their promoters • It was found that some thalassemia cases were due to deletions that altered the LCR regions, causing abnormal expre ...
A Small GTPase of the Rab Family Is Required for Root Hair
... provided functional clues, overexpression and antisense silencing of different Rabs in other species resulted in developmental and morphological phenotypes. Tomato (Solanum lycopersicum) Rab11 silencing produced defects in secretion of cell wall degrading enzymes, cell wall loosening, determinate gr ...
... provided functional clues, overexpression and antisense silencing of different Rabs in other species resulted in developmental and morphological phenotypes. Tomato (Solanum lycopersicum) Rab11 silencing produced defects in secretion of cell wall degrading enzymes, cell wall loosening, determinate gr ...
Evidence for land plant cell wall biosynthetic mechanisms in
... GTs in their genomes than any land plants (Ulvskov et al., 2013). Due to the lack of a sequenced CGA genome, only a few GTs in the CGA have been cloned or otherwise described. Here, we provide genetic evidence of the evolution of cell wall biosynthesis in the CGA through analysis of available CGA tr ...
... GTs in their genomes than any land plants (Ulvskov et al., 2013). Due to the lack of a sequenced CGA genome, only a few GTs in the CGA have been cloned or otherwise described. Here, we provide genetic evidence of the evolution of cell wall biosynthesis in the CGA through analysis of available CGA tr ...
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... secretion of a myocardial proliferative factor (Merki et al., 2005). However, RA has never been linked directly to epicardial function, and the factor secreted by the epicardium that stimulates myocardial expansion has remained elusive. Several growth factors have been suggested to function in commu ...
... secretion of a myocardial proliferative factor (Merki et al., 2005). However, RA has never been linked directly to epicardial function, and the factor secreted by the epicardium that stimulates myocardial expansion has remained elusive. Several growth factors have been suggested to function in commu ...
... receptors for M. pneumoniae are long chain sialo-oligosaccharides of I and i antigen type (i.e. oligosaccharides of poly N-acetyllactosamine series, presenting sialic acid joined by alpha 2-3 linkage to their penultimate galactose residues) that occur on glycoproteins and on different glycolipids [5 ...
AtMYB41 activates ectopic suberin synthesis and assembly in
... and that the production of suberin aliphatics in N. benthamiana leaves is not a general consequence of overexpressing Arabidopsis MYB transcription factors. Similarly, the observed induction of suberin-type monomers by transient overexpression of AtMYB41 is not a general consequence of wounding by t ...
... and that the production of suberin aliphatics in N. benthamiana leaves is not a general consequence of overexpressing Arabidopsis MYB transcription factors. Similarly, the observed induction of suberin-type monomers by transient overexpression of AtMYB41 is not a general consequence of wounding by t ...
Linköping University Post Print
... according to their active site amino acids, into cysteine (cathepsins B, C, F, H, K, L, O, S, V, W, and X), serine (cathepsins A and G), and aspartic cathepsins (cathepsins D and E) [3]. Cell death through apoptosis is tightly controlled by changes in protein expression, proteinprotein interactions, ...
... according to their active site amino acids, into cysteine (cathepsins B, C, F, H, K, L, O, S, V, W, and X), serine (cathepsins A and G), and aspartic cathepsins (cathepsins D and E) [3]. Cell death through apoptosis is tightly controlled by changes in protein expression, proteinprotein interactions, ...
Mechanics and Modeling of Plant Cell Growth
... processes have key mechanical aspects that have prompted numerous attempts to generate theoretical, mechanical, and biophysical models. In the present review we will focus on cellular expansive growth in walled cells typical for plants, algae and fungi. Given that walled cells rarely migrate, cell e ...
... processes have key mechanical aspects that have prompted numerous attempts to generate theoretical, mechanical, and biophysical models. In the present review we will focus on cellular expansive growth in walled cells typical for plants, algae and fungi. Given that walled cells rarely migrate, cell e ...
Negative feedback control of the autoimmune
... foreign and self-antigens (Moore et al., 2001) that are primarily mediated by its inhibitory activities on the function of APCs (de Waal Malefyt et al., 1991). Although the role of IL-10 in suppression of experimental autoimmune encephalomyelitis in the Tg4 model is not known, the effect of IL-10 on ...
... foreign and self-antigens (Moore et al., 2001) that are primarily mediated by its inhibitory activities on the function of APCs (de Waal Malefyt et al., 1991). Although the role of IL-10 in suppression of experimental autoimmune encephalomyelitis in the Tg4 model is not known, the effect of IL-10 on ...