Microsporidia: Why Make Nucleotides if You Can Steal Them?
... Microsporidia and the recycling of nucleotides The continual turnover of RNA, which releases the nucleoside monophosphates, represents a major, ready-made source of nucleotides [27]. The enzymes needed to regenerate nucleoside triphosphates following nucleic acid degradation have been retained by mi ...
... Microsporidia and the recycling of nucleotides The continual turnover of RNA, which releases the nucleoside monophosphates, represents a major, ready-made source of nucleotides [27]. The enzymes needed to regenerate nucleoside triphosphates following nucleic acid degradation have been retained by mi ...
S1P promotes murine progenitor cell egress and
... various cytokines, chemokines, proteolytic enzymes, and adhesion molecules3-5 through a dynamic interplay between the immune and nervous systems within the bone microenvironment.1,2,6-8 HSPC mobilization can be clinically induced by a variety of cytokines and drugs, such as granulocyte colony stimul ...
... various cytokines, chemokines, proteolytic enzymes, and adhesion molecules3-5 through a dynamic interplay between the immune and nervous systems within the bone microenvironment.1,2,6-8 HSPC mobilization can be clinically induced by a variety of cytokines and drugs, such as granulocyte colony stimul ...
Calcium Signaling. Cell 131: 1047
... plasma membranes by its acyl chains, whereas calmodulin is soluble and cytosolic. Both are ubiquitous and abundant. Clusters of positively charged residues on many peripheral (e.g., K-Ras, MARCKS) and integral (e.g., the juxtamembrane regions of ion channels and the EGFR) proteins produce a local po ...
... plasma membranes by its acyl chains, whereas calmodulin is soluble and cytosolic. Both are ubiquitous and abundant. Clusters of positively charged residues on many peripheral (e.g., K-Ras, MARCKS) and integral (e.g., the juxtamembrane regions of ion channels and the EGFR) proteins produce a local po ...
AHEART December 46/6 - AJP
... of morphine to anesthetized open-chest rats and isolated rabbit hearts has been reported to mimic the infarct-limiting effect of ischemic preconditioning (24, 38). Together, these studies suggest that endogenous opioid peptides participate in the cardioprotective phenomenon of ischemic preconditioni ...
... of morphine to anesthetized open-chest rats and isolated rabbit hearts has been reported to mimic the infarct-limiting effect of ischemic preconditioning (24, 38). Together, these studies suggest that endogenous opioid peptides participate in the cardioprotective phenomenon of ischemic preconditioni ...
Det här verket är upphovrättskyddat enligt Lagen (1960
... cells, into the follicle lumen. In its earliest stage the pseudopod has the appearance of a longitudinal fold. This fold curies, its margins fuse and a double-walled tube, open at the top, is formed. The tube is then closed and the pseudopod is transformed into a cystlike or more irregular structure ...
... cells, into the follicle lumen. In its earliest stage the pseudopod has the appearance of a longitudinal fold. This fold curies, its margins fuse and a double-walled tube, open at the top, is formed. The tube is then closed and the pseudopod is transformed into a cystlike or more irregular structure ...
Review
... plasma membranes by its acyl chains, whereas calmodulin is soluble and cytosolic. Both are ubiquitous and abundant. Clusters of positively charged residues on many peripheral (e.g., K-Ras, MARCKS) and integral (e.g., the juxtamembrane regions of ion channels and the EGFR) proteins produce a local po ...
... plasma membranes by its acyl chains, whereas calmodulin is soluble and cytosolic. Both are ubiquitous and abundant. Clusters of positively charged residues on many peripheral (e.g., K-Ras, MARCKS) and integral (e.g., the juxtamembrane regions of ion channels and the EGFR) proteins produce a local po ...
Inner Blood-Retinal Barrier Transporters: Relevance to
... circulating blood (Wolburg et al., 2009). In particular, D-mannitol, a representative nonpermeable paracellular marker, exhibits very low blood-to-retina influx permeability while D-glucose and amino acids, the substrates of membrane transporter molecules, exhibit over a 300-fold higher permeability ...
... circulating blood (Wolburg et al., 2009). In particular, D-mannitol, a representative nonpermeable paracellular marker, exhibits very low blood-to-retina influx permeability while D-glucose and amino acids, the substrates of membrane transporter molecules, exhibit over a 300-fold higher permeability ...
fist: an Arabidopsis mutant with altered cell division planes and
... bryogenesis in wild-type Arabidopsis is characterised by a series of invariant cell cleavages (Mansfield and Briarty 1991), as illustrated in the bright-field micrographs shown in Figure 3a–f. Following fertilisation (Fig. 3a), the elongated zygote (Fig. 3b) undergoes an asymmetrical transverse divi ...
... bryogenesis in wild-type Arabidopsis is characterised by a series of invariant cell cleavages (Mansfield and Briarty 1991), as illustrated in the bright-field micrographs shown in Figure 3a–f. Following fertilisation (Fig. 3a), the elongated zygote (Fig. 3b) undergoes an asymmetrical transverse divi ...
Chapter 32: DNA Replication in Yeast
... regulatory role for this subunit. A speculative model is that the nonphosphorylated form of this subunit is required for loading pol-a:primase at replication origins by direct or indirect interactions with the origin recognition complex (Foiani et al. 1994). Additional proteins that interact with th ...
... regulatory role for this subunit. A speculative model is that the nonphosphorylated form of this subunit is required for loading pol-a:primase at replication origins by direct or indirect interactions with the origin recognition complex (Foiani et al. 1994). Additional proteins that interact with th ...
Mesoderm commitment to hematopoiesis - Development
... vessels (Bielinska et al., 1996). In addition to the influence of cell populations such as endoderm, findings from studies using Xenopus animal cap induction assays, mouse knockouts and embryoid body differentiation have implicated specific molecules including activin, fibroblast growth factors and ...
... vessels (Bielinska et al., 1996). In addition to the influence of cell populations such as endoderm, findings from studies using Xenopus animal cap induction assays, mouse knockouts and embryoid body differentiation have implicated specific molecules including activin, fibroblast growth factors and ...
ZEBRANECROSIS, a thylakoidbound protein, is critical for the
... mutant phenotype is formed by unequal impairment of chloroplast biogenesis before emergence from the leaf sheath under alternate light/dark or high/low temperatures (restrictive), but not under constant light and temperature (permissive) conditions. Map-based cloning revealed that ZN encodes a thyla ...
... mutant phenotype is formed by unequal impairment of chloroplast biogenesis before emergence from the leaf sheath under alternate light/dark or high/low temperatures (restrictive), but not under constant light and temperature (permissive) conditions. Map-based cloning revealed that ZN encodes a thyla ...
Activation of Hedgehog signaling by loss of GNAS causes
... progenitor cells. In progressive osseous heteroplasia, a human disease caused by null mutations in GNAS, which encodes Gas, Hedgehog signaling is upregulated in ectopic osteoblasts and progenitor cells. In animal models, we show that geneticallymediated ectopic Hedgehog signaling is sufficient to in ...
... progenitor cells. In progressive osseous heteroplasia, a human disease caused by null mutations in GNAS, which encodes Gas, Hedgehog signaling is upregulated in ectopic osteoblasts and progenitor cells. In animal models, we show that geneticallymediated ectopic Hedgehog signaling is sufficient to in ...
Microtubule-associated protein 1b is required for shaping the neural
... monopolar protrusions (filopodia and lamellipodia) directed towards the midline [11, 13, 14]. We have previously demonstrated that cells in the zebrafish neural plate also extend medially-oriented protrusions and elongate as they converge towards the midline [8]. Narrowing of the neural plate in mic ...
... monopolar protrusions (filopodia and lamellipodia) directed towards the midline [11, 13, 14]. We have previously demonstrated that cells in the zebrafish neural plate also extend medially-oriented protrusions and elongate as they converge towards the midline [8]. Narrowing of the neural plate in mic ...
Ingredient of the Month - American Culinary Federation
... and come in many varieties—some with moderately thick shells and others with thin and easy-to-crack shells. They are available year-round and come in three main sizes: large, medium and babies. Also known as the Persian or European walnuts, they are delicious in all kinds of sweet and savory dishes. ...
... and come in many varieties—some with moderately thick shells and others with thin and easy-to-crack shells. They are available year-round and come in three main sizes: large, medium and babies. Also known as the Persian or European walnuts, they are delicious in all kinds of sweet and savory dishes. ...
A novel meiosisspecific protein of fission yeast, Meu13p, promotes
... performed northern hybridization using a meu13+ cDNA probe on total RNA extracted from diploid cells that were synchronously undergoing meiosis. As shown in Figure 1B, the expression of meu13+ began to increase after meiosis was induced by nitrogen starvation and it peaked 6 h after meiotic inductio ...
... performed northern hybridization using a meu13+ cDNA probe on total RNA extracted from diploid cells that were synchronously undergoing meiosis. As shown in Figure 1B, the expression of meu13+ began to increase after meiosis was induced by nitrogen starvation and it peaked 6 h after meiotic inductio ...
Regulative germ cell specification in axolotl embryos: a primitive trait
... specified cell-autonomously. Several studies have demonstrated that BMPs (members of the TGF-b family of signalling molecules) secreted from adjacent extraembryonic tissues are required for the production of PGCs in mouse embryos (Lawson et al. 1999; Ying & Zhao 2001; Ying et al. 2001). Moreover, re ...
... specified cell-autonomously. Several studies have demonstrated that BMPs (members of the TGF-b family of signalling molecules) secreted from adjacent extraembryonic tissues are required for the production of PGCs in mouse embryos (Lawson et al. 1999; Ying & Zhao 2001; Ying et al. 2001). Moreover, re ...
Fibronectin and radial intercalation
... is convergent extension. However, others have reported that inhibition of integrin/FN interactions in Xenopus results in delayed blastopore closure, axial defects and ectodermal thickening (Johnson et al., 1993; Ramos and DeSimone, 1996; Ramos et al., 1996). This indicates that FN may play more subt ...
... is convergent extension. However, others have reported that inhibition of integrin/FN interactions in Xenopus results in delayed blastopore closure, axial defects and ectodermal thickening (Johnson et al., 1993; Ramos and DeSimone, 1996; Ramos et al., 1996). This indicates that FN may play more subt ...
Genetic Models of Mechanotransduction: The
... tension (4, 25, 38, 40, 392). They have been studied in detail by patch-clamp methodologies in giant spheroplasts and in reconstituted membrane fractions (168, 278, 392). Based on their conductance and sensitivity to negative pressure applied to the patch-clamp pipette, three types of mechanosensiti ...
... tension (4, 25, 38, 40, 392). They have been studied in detail by patch-clamp methodologies in giant spheroplasts and in reconstituted membrane fractions (168, 278, 392). Based on their conductance and sensitivity to negative pressure applied to the patch-clamp pipette, three types of mechanosensiti ...
Efficient Procedure and Methods to Determine Critical
... named electro-chemotherapy [5-7] and gene electro-transfer [8,9], respectively. In the past decade, non-thermal irreversible electroporation for the ablation of solid tumors has emerged as a new medical application of electroporation technology [3, 10]. In the food and pharmaceutical application, el ...
... named electro-chemotherapy [5-7] and gene electro-transfer [8,9], respectively. In the past decade, non-thermal irreversible electroporation for the ablation of solid tumors has emerged as a new medical application of electroporation technology [3, 10]. In the food and pharmaceutical application, el ...
A1982PM90100001
... ‘When I joined David Mollin’s laboratory at the Royal Postgraduate Medical School, London, in 1963, the assay of serum folate microbiologically using Lactobacillus casei had recently 1been established. Studies by2 Victor Herbert in the US and Alan Waters in Mollin’s laboratory had shown that folate ...
... ‘When I joined David Mollin’s laboratory at the Royal Postgraduate Medical School, London, in 1963, the assay of serum folate microbiologically using Lactobacillus casei had recently 1been established. Studies by2 Victor Herbert in the US and Alan Waters in Mollin’s laboratory had shown that folate ...
The essential role of anionic transport in plant cells
... patch–clamp technique to several cellular types and functional information on transport systems present in the plasma membrane to be obtained. In general, the resting potential of the majority of plant cells is more negative than –100 mV. Therefore the command voltages required for voltage activatio ...
... patch–clamp technique to several cellular types and functional information on transport systems present in the plasma membrane to be obtained. In general, the resting potential of the majority of plant cells is more negative than –100 mV. Therefore the command voltages required for voltage activatio ...
Arabidopsis – a powerful model system for plant cell wall research
... Lertpiriyapong and Sung (2003), Pagant et al. (2002) Endo et al. (2009) ...
... Lertpiriyapong and Sung (2003), Pagant et al. (2002) Endo et al. (2009) ...
A Per-ARNT-Sim-Like Sensor Domain Uniquely
... mutation. The results of the REV MEKHLA domain mutagenesis performed for the reverse Y2H assay are annotated over the asterisk line. The red triangle indicates a four–amino acid stretch that is REV unique. (B) Crystal structure of the PAS A domain of the A. vinelandii NifL protein. This PAS domain b ...
... mutation. The results of the REV MEKHLA domain mutagenesis performed for the reverse Y2H assay are annotated over the asterisk line. The red triangle indicates a four–amino acid stretch that is REV unique. (B) Crystal structure of the PAS A domain of the A. vinelandii NifL protein. This PAS domain b ...
Automatic sampling for unbiased and efficient stereological
... The proportionator combination of biased image analysis and non-uniform sampling leading to unbiased estimation was previously studied using simulation (Gardi et al. 2007). The proportionator combines computerized image analysis and non-uniform sampling, providing a more precise estimates using less ...
... The proportionator combination of biased image analysis and non-uniform sampling leading to unbiased estimation was previously studied using simulation (Gardi et al. 2007). The proportionator combines computerized image analysis and non-uniform sampling, providing a more precise estimates using less ...
Biochemical and Molecular Characterization of a
... free myo-inositol content of the LR33-derived seeds might be the cause of the decreased raffinosaccharide content at maturity, tissue slice feeding studies were done using 1-mm tissue slices taken from developing soybean embryos during the period of raffinosaccharide synthesis. In preliminary experi ...
... free myo-inositol content of the LR33-derived seeds might be the cause of the decreased raffinosaccharide content at maturity, tissue slice feeding studies were done using 1-mm tissue slices taken from developing soybean embryos during the period of raffinosaccharide synthesis. In preliminary experi ...