Endocrine System PPT
... produced in one part of the body that travels to another part of the body (target tissue) and elicits a response. ...
... produced in one part of the body that travels to another part of the body (target tissue) and elicits a response. ...
Protein Analysis - GRiSP Research Solutions
... Western blotting is a widely-used analytical technique for the study of proteins. This method, first described by Towbin, et. al1, allows for the detection of a single protein within a mixture of proteins derived from a biological sample. The specificity of Western blotting is achieved by using an a ...
... Western blotting is a widely-used analytical technique for the study of proteins. This method, first described by Towbin, et. al1, allows for the detection of a single protein within a mixture of proteins derived from a biological sample. The specificity of Western blotting is achieved by using an a ...
The protein import apparatus of chloroplasts
... data indicate that a tightly folded polypeptide which is "arrested" in its conformation can not be converted by the translocation machinery into a form which is productively imported. Similar results had heen obtained earlier for mitochondrial protein translocation (Eikrs and Schatz 1986: for a revi ...
... data indicate that a tightly folded polypeptide which is "arrested" in its conformation can not be converted by the translocation machinery into a form which is productively imported. Similar results had heen obtained earlier for mitochondrial protein translocation (Eikrs and Schatz 1986: for a revi ...
Anthraquinone emodin inhibits human cancer
... a more invasive potency (2). At the time being, there is no specific treatment targeting metastases or preventing metastasis development. Moreover, metastatic cells often exhibit resistance to conventional therapies such as chemotherapies, rendering even more difficult to treat the diseases. Althoug ...
... a more invasive potency (2). At the time being, there is no specific treatment targeting metastases or preventing metastasis development. Moreover, metastatic cells often exhibit resistance to conventional therapies such as chemotherapies, rendering even more difficult to treat the diseases. Althoug ...
Epithelial invasion and cell lysis by virulent strains of Streptococcus
... The ¢rst step in generating an active infection could be a breach of the mucosal epithelia in the upper respiratory tract. Recent investigations with group B (GBS) and group A streptococci (GAS) have shown that while adherence to HEp-2 epithelial cells and virulence may not always correlate well, th ...
... The ¢rst step in generating an active infection could be a breach of the mucosal epithelia in the upper respiratory tract. Recent investigations with group B (GBS) and group A streptococci (GAS) have shown that while adherence to HEp-2 epithelial cells and virulence may not always correlate well, th ...
γ-Tubulin Is Essential for Microtubule Organization and
... drastic depletion of g-tubulin levels in both double mutant combinations. Transcript levels are generally poor indicators of molecular defects in insertional mutants. Therefore, we used an anti-g-tubulin antibody to determine protein levels in double mutant plantlets by protein gel blot analysis. To ...
... drastic depletion of g-tubulin levels in both double mutant combinations. Transcript levels are generally poor indicators of molecular defects in insertional mutants. Therefore, we used an anti-g-tubulin antibody to determine protein levels in double mutant plantlets by protein gel blot analysis. To ...
lecture 8
... but recent study shows only a portion of those are completely chaperonin-dependent Belongs to so-called Group I chaperonins which includes evolutionarily-related bacterial GroEL, mitochondrial Hsp60, and chloroplast Rubisco subunit-binding protein (Rubisco is most abundant protein on earth and req ...
... but recent study shows only a portion of those are completely chaperonin-dependent Belongs to so-called Group I chaperonins which includes evolutionarily-related bacterial GroEL, mitochondrial Hsp60, and chloroplast Rubisco subunit-binding protein (Rubisco is most abundant protein on earth and req ...
Defining new SNARE functions: the i-SNARE
... SNAREs accumulation outside active complexes may gain a structural role in the maintenance of membrane identity. The equilibrium between fusogenic (tSNARE) and non fusogenic (i-SNARE) activity of specific SNAREs may reside on their localization, as highlighted for SYP51 and SYP52 (De Benedictis et a ...
... SNAREs accumulation outside active complexes may gain a structural role in the maintenance of membrane identity. The equilibrium between fusogenic (tSNARE) and non fusogenic (i-SNARE) activity of specific SNAREs may reside on their localization, as highlighted for SYP51 and SYP52 (De Benedictis et a ...
Chronic Immune Reactivity Against Persisting Microbial Antigen in
... through the viral US28 gene product which functions as a chemokine receptor and enhances the migration of smooth muscle cells in response to inflammatory chemokines.9 Likewise, the chemokine receptor M33 of the murine CMV (MCMV) is essential for MCMV-induced migration of vascular smooth muscle cells ...
... through the viral US28 gene product which functions as a chemokine receptor and enhances the migration of smooth muscle cells in response to inflammatory chemokines.9 Likewise, the chemokine receptor M33 of the murine CMV (MCMV) is essential for MCMV-induced migration of vascular smooth muscle cells ...
Protein Motif Recognition I Introduction
... address coiled coils, although the techniques can be extended to recognizing other motifs. Our focus will be on the following question: given a subsequence of amino acid residues, does it fold into a coiled coil? Determining experimentally whether a subsequence folds into a coiled coil can be quite ...
... address coiled coils, although the techniques can be extended to recognizing other motifs. Our focus will be on the following question: given a subsequence of amino acid residues, does it fold into a coiled coil? Determining experimentally whether a subsequence folds into a coiled coil can be quite ...
selection of kidney cell types in primary glomerular explant
... glomerular attachment and the type of cells produced in culture. Quantitative studies demonstrated selection of cell types by different culture conditions. Three colony types, each composed of distinctive cell types, could be identified by morphological features. The cells constituting two of these ...
... glomerular attachment and the type of cells produced in culture. Quantitative studies demonstrated selection of cell types by different culture conditions. Three colony types, each composed of distinctive cell types, could be identified by morphological features. The cells constituting two of these ...
as a PDF
... in activiTIes between A and B, combined with their structural complexities, provides opportunities for chemical modifications. Both A and B were only moderately effective against cutaneous HSV infections in mice, and inactive against Semliki Forest virus. Further reports on this interesting class of ...
... in activiTIes between A and B, combined with their structural complexities, provides opportunities for chemical modifications. Both A and B were only moderately effective against cutaneous HSV infections in mice, and inactive against Semliki Forest virus. Further reports on this interesting class of ...
Full Text - Digital Access to Scholarship at Harvard
... understanding of inhibitory molecules and pathways regulating melanoma initiation and progression that could be used as therapeutic targets or biomarkers is needed. Several studies have reported expression of Treg specific markers such as Foxp3 (forkhead-box-protein p3), CD39, or other stromal mark ...
... understanding of inhibitory molecules and pathways regulating melanoma initiation and progression that could be used as therapeutic targets or biomarkers is needed. Several studies have reported expression of Treg specific markers such as Foxp3 (forkhead-box-protein p3), CD39, or other stromal mark ...
Recent developments in atomic force microscopy for underwater
... biological materials, including plant cell walls. AFM provides a critical imaging ability to investigate cell walls at the nanometer scale with no complex sample preparation or perturbation. In 1997, Baker et al. first reported AFM measurements of the surfaces of the Valonia cellulose crystals [1]. ...
... biological materials, including plant cell walls. AFM provides a critical imaging ability to investigate cell walls at the nanometer scale with no complex sample preparation or perturbation. In 1997, Baker et al. first reported AFM measurements of the surfaces of the Valonia cellulose crystals [1]. ...
Theory notes task worksheets etc answers
... Worksheets can be hidden from other users leading to confidentiality of individual departments’ data They ensure that records do not get mixed up, each worksheet can have its own access rights Totals can be summarised on a master worksheet Charts can be used on a worksheet to summarise data ...
... Worksheets can be hidden from other users leading to confidentiality of individual departments’ data They ensure that records do not get mixed up, each worksheet can have its own access rights Totals can be summarised on a master worksheet Charts can be used on a worksheet to summarise data ...
University of Zurich - Institute of Molecular Life Sciences
... (3). This is remarkable since Ad3 had been suggested to use other receptors besides CD46 (61, 95). Notably, it was recently shown that Ad3 binds to the same region of the terminal short consensus repeat 1 (SCR1) and SCR2 of CD46 as Ad35, albeit with lower affinity than Ad35 (25, 26), and this leads ...
... (3). This is remarkable since Ad3 had been suggested to use other receptors besides CD46 (61, 95). Notably, it was recently shown that Ad3 binds to the same region of the terminal short consensus repeat 1 (SCR1) and SCR2 of CD46 as Ad35, albeit with lower affinity than Ad35 (25, 26), and this leads ...
GABRA1 (gamma-aminobutyric acid (GABA) A receptor. alpha 1
... Similarity: Belongs to the ligand-gated ionic channel (TC 1.A.9) family [view classification]. Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modu ...
... Similarity: Belongs to the ligand-gated ionic channel (TC 1.A.9) family [view classification]. Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modu ...
BCL-xL-Dependent Light Scattering by Apoptotic Cells
... scatter-intensity ratio was correlated with mitochondrial rounding in response to an increase in intracellular calcium (Boustany et al., 2002). In this report we show that intracellular changes in angular light scattering can be detected within the first 60 min of apoptosis, several hours before pho ...
... scatter-intensity ratio was correlated with mitochondrial rounding in response to an increase in intracellular calcium (Boustany et al., 2002). In this report we show that intracellular changes in angular light scattering can be detected within the first 60 min of apoptosis, several hours before pho ...
Statistical Approaches to Use a Model Organism for
... A major goal of bioinformatics is the characterization of transcription factors and the transcriptional programs they regulate. Given the speed of genome sequencing, we would like to quickly annotate regulatory sequences in newly-sequenced genomes. In such cases, it would be helpful to predict seque ...
... A major goal of bioinformatics is the characterization of transcription factors and the transcriptional programs they regulate. Given the speed of genome sequencing, we would like to quickly annotate regulatory sequences in newly-sequenced genomes. In such cases, it would be helpful to predict seque ...
Paper
... Ludwig et al, 1988; Basler et al, 2007). This represents a remarkable difference between the two RTX toxins, which could be accounted for by the specific structure of the RTX domain of CyaA that contains many more calcium binding repeats (~40), as compared to the 13 repeats found in HlyA (Ludwig et ...
... Ludwig et al, 1988; Basler et al, 2007). This represents a remarkable difference between the two RTX toxins, which could be accounted for by the specific structure of the RTX domain of CyaA that contains many more calcium binding repeats (~40), as compared to the 13 repeats found in HlyA (Ludwig et ...
Local opening of the DNA double helix in eukaryotic cells detected by
... fluorescence distribution with the corresponding phase-contrast image of the nucleus (Fig. 3A) and with the fluorescence pattern produced by a DNA-staining dye (DAPI) (Fig. 3B) leads to the conclusion that the unstained or weakly stained areas were nucleoli (Fig. 3D) and/or condensed A+T-rich chroma ...
... fluorescence distribution with the corresponding phase-contrast image of the nucleus (Fig. 3A) and with the fluorescence pattern produced by a DNA-staining dye (DAPI) (Fig. 3B) leads to the conclusion that the unstained or weakly stained areas were nucleoli (Fig. 3D) and/or condensed A+T-rich chroma ...
Transcription- and translation-dependent changes in membrane
... viscosity is energy dependent: it did not happen in KCN-treated cells. All treatments decreasing membrane viscosity also induced nucleoid compaction and fusion. Inhibition of macromolecular synthesis without membrane perturbation caused nucleoids to expand. Changes in membrane dynamics were also dis ...
... viscosity is energy dependent: it did not happen in KCN-treated cells. All treatments decreasing membrane viscosity also induced nucleoid compaction and fusion. Inhibition of macromolecular synthesis without membrane perturbation caused nucleoids to expand. Changes in membrane dynamics were also dis ...
Human cerebrospinal fluid contains exosomes that represent a
... One of the pathological hallmarks of neurodegenerative diseases, such as spongiform encephalopathies (TSEs) and Alzheimer's dementia (AD), is the accumulation of abnormal proteins within brain tissue (prions in TSEs and b-amyloid in AD). Studies in cell culture have demonstrated these proteins are r ...
... One of the pathological hallmarks of neurodegenerative diseases, such as spongiform encephalopathies (TSEs) and Alzheimer's dementia (AD), is the accumulation of abnormal proteins within brain tissue (prions in TSEs and b-amyloid in AD). Studies in cell culture have demonstrated these proteins are r ...
Synthesis of Substituted Alkanethiols Intended for Protein Immobilization -Chelate Associated Photochemistry (CAP)
... surface chemistry we hope to contribute to the development of large-scale screening systems and microarrays based on His-tagged labeled biomolecules. This will be used in a number of ...
... surface chemistry we hope to contribute to the development of large-scale screening systems and microarrays based on His-tagged labeled biomolecules. This will be used in a number of ...
29. protein targeting and degradation
... The pathways by which proteins are sorted and transported to their proper cellular locations are referred to as protein targeting pathways. A characteristic feature of these targeting pathways (with the exception of cytosolic and nuclear proteins) is the presence of a short amino acid sequence at th ...
... The pathways by which proteins are sorted and transported to their proper cellular locations are referred to as protein targeting pathways. A characteristic feature of these targeting pathways (with the exception of cytosolic and nuclear proteins) is the presence of a short amino acid sequence at th ...