
Primordial germ cells migration: morphological and molecular aspects
... four mechanisms have been hypothesized to explain PGC migration: attraction by chemotactic factors, PGCPGC interactions, substrate-guidance, and interaction with extracellular matrix molecules. We have demonstrated that a repertory of extracellular matrix molecules, proteoglycans in particular, are ...
... four mechanisms have been hypothesized to explain PGC migration: attraction by chemotactic factors, PGCPGC interactions, substrate-guidance, and interaction with extracellular matrix molecules. We have demonstrated that a repertory of extracellular matrix molecules, proteoglycans in particular, are ...
T Cells + Memory CD8 Influenza A Virus
... of 9 aa (10 –12). Recent studies also suggest that CD8⫹DbPA224 T cells have a higher avidity TCR-peptide-MHC interaction when compared with their CD8⫹DbNP366 counterparts (13). This interaction is characterized by a slower tetramer dissociation rate and less dependence on the CD8 coreceptor for IFN ...
... of 9 aa (10 –12). Recent studies also suggest that CD8⫹DbPA224 T cells have a higher avidity TCR-peptide-MHC interaction when compared with their CD8⫹DbNP366 counterparts (13). This interaction is characterized by a slower tetramer dissociation rate and less dependence on the CD8 coreceptor for IFN ...
Bio1A - Lec 6 slides File
... • built as a twisted double chain of actin subunits • structural role - to bear tension, resisting pulling forces within the cell ...
... • built as a twisted double chain of actin subunits • structural role - to bear tension, resisting pulling forces within the cell ...
Characterization of Escherichia coli Flagellar Mutants That are
... flagella (as judged by the ability of His. strains MS1822 and MS1823 to swim on minimal motility agar plus glucose). The f'irst cfs mutation was mobilized in this manner. To mobilize mutations f'rom other Cf's strains (and f'rom MS 1829 again), a similar approach was used except with a derivative of ...
... flagella (as judged by the ability of His. strains MS1822 and MS1823 to swim on minimal motility agar plus glucose). The f'irst cfs mutation was mobilized in this manner. To mobilize mutations f'rom other Cf's strains (and f'rom MS 1829 again), a similar approach was used except with a derivative of ...
Detergent-resistant plasma membrane proteome to elucidate
... plasma membrane (PM), recent studies suggest that the PM is in fact non-uniform structure that includes a number of lateral domains enriched in specific components (i.e., sterols, sphingolipids, and some kind of proteins). These domains are called as microdomains and considered to be the platform of ...
... plasma membrane (PM), recent studies suggest that the PM is in fact non-uniform structure that includes a number of lateral domains enriched in specific components (i.e., sterols, sphingolipids, and some kind of proteins). These domains are called as microdomains and considered to be the platform of ...
Suppressing cardiac arrhythmia by targeting the
... Abnormal Ca2+ handling in cardiac muscle cells is associated with a wide range of human cardiac diseases, including heart failure and cardiac arrhythmia. Animal models suitable for large-scale screening techniques are potent tools to identify novel Ca2+ handling mechanisms associated with these dise ...
... Abnormal Ca2+ handling in cardiac muscle cells is associated with a wide range of human cardiac diseases, including heart failure and cardiac arrhythmia. Animal models suitable for large-scale screening techniques are potent tools to identify novel Ca2+ handling mechanisms associated with these dise ...
Exocytosis and cell polarity in plants exocyst and recycling domains
... In metazoans, vesiculation of the whole Golgi complex takes place during mitosis; it can also be induced by ilimaquinone (Bard & Malhotra, 2006). This process, as well as TPC formation, requires trimeric G-proteins and a serine/threonine protein kinase D (PKD) interacting with DAG membrane domains ( ...
... In metazoans, vesiculation of the whole Golgi complex takes place during mitosis; it can also be induced by ilimaquinone (Bard & Malhotra, 2006). This process, as well as TPC formation, requires trimeric G-proteins and a serine/threonine protein kinase D (PKD) interacting with DAG membrane domains ( ...
- Wiley Online Library
... half of these patients die [3]. Shock may be induced by several distinct mechanisms. Cases associated with Gram-negative bacteria result from the overstimulation of macrophages by lipopolysaccharide (LPS) present in the outer membrane. The activated macrophages produce excessive amounts of cytokines ...
... half of these patients die [3]. Shock may be induced by several distinct mechanisms. Cases associated with Gram-negative bacteria result from the overstimulation of macrophages by lipopolysaccharide (LPS) present in the outer membrane. The activated macrophages produce excessive amounts of cytokines ...
PDF - Blood Journal
... Phase separation of vesicle proteins in Triton X-114 solution The phase separation of membrane proteins in Triton X-114 according to the difference in hydrophobicity32 was applied with slight modifications. To purify Triton X-114, the precondensation of the detergent was performed 3 times, as recomm ...
... Phase separation of vesicle proteins in Triton X-114 solution The phase separation of membrane proteins in Triton X-114 according to the difference in hydrophobicity32 was applied with slight modifications. To purify Triton X-114, the precondensation of the detergent was performed 3 times, as recomm ...
fine structure and morphogenic movements in the
... vacuoles surrounded by layers of membranes. The cells lining the groove are tightly joined at their distal ends in the region of the dense layer. Proximally, the cell bodies are separated by wide intercellular spaces. The cell body, which is migrating toward the interior of the gastrula, contains th ...
... vacuoles surrounded by layers of membranes. The cells lining the groove are tightly joined at their distal ends in the region of the dense layer. Proximally, the cell bodies are separated by wide intercellular spaces. The cell body, which is migrating toward the interior of the gastrula, contains th ...
Antigen-Presenting Cells Are Stratified Within Normal Human
... The function of corneal APCs remains an area of active investigation. In a murine model of HSV-1 corneal infection, it was recently shown that corneal resident or early responding blood-derived DCs react rapidly to HSV-1 infection and are required to attract natural killer cells and inflammatory mon ...
... The function of corneal APCs remains an area of active investigation. In a murine model of HSV-1 corneal infection, it was recently shown that corneal resident or early responding blood-derived DCs react rapidly to HSV-1 infection and are required to attract natural killer cells and inflammatory mon ...
Accurate cell segmentation in microscopy images using membrane
... solution, it thus seems that the field is diverging, and by now almost as many cell segmentation methods have been developed as there exist cell analysis problems . . .’ (Meijering, 2012). Cell segmentation is challenging (Peng, 2008) for many reasons. First, segmenting cellular images requires the ...
... solution, it thus seems that the field is diverging, and by now almost as many cell segmentation methods have been developed as there exist cell analysis problems . . .’ (Meijering, 2012). Cell segmentation is challenging (Peng, 2008) for many reasons. First, segmenting cellular images requires the ...
chapter 9 telomeres and telomerase in adult stem cells and
... difficulties and ethical controversies associated with SCNT (Fig. 1), which involve the generation and destruction of human embryos. Full characterization of iPS cells is still in progress, but initial studies indicate that iPS cells have the same properties as ES cells, including similar global gen ...
... difficulties and ethical controversies associated with SCNT (Fig. 1), which involve the generation and destruction of human embryos. Full characterization of iPS cells is still in progress, but initial studies indicate that iPS cells have the same properties as ES cells, including similar global gen ...
F-Actin-Dependent Endocytosis of Cell Wall
... rinuclear positions and maintained the longest distance from each other at the opposite sides of centrally positioned nuclei matching cellular polarity axes (Fig. 1, E and F). In the elongation region, only epidermal cells embarking on root hair formation formed BFA compartments (Fig. 1F), whereas a ...
... rinuclear positions and maintained the longest distance from each other at the opposite sides of centrally positioned nuclei matching cellular polarity axes (Fig. 1, E and F). In the elongation region, only epidermal cells embarking on root hair formation formed BFA compartments (Fig. 1F), whereas a ...
Epstein-Barr virus genetics: talking about the BAC generation Open Access
... of interest and subsequently exposing an EBV-negative cell line to the supernatants from these cells. This was performed at a low multiplicity of infection to ensure that every newly infected cell would carry either the mutant or the wild type viruses [7]. The B cell clones would then be screened fo ...
... of interest and subsequently exposing an EBV-negative cell line to the supernatants from these cells. This was performed at a low multiplicity of infection to ensure that every newly infected cell would carry either the mutant or the wild type viruses [7]. The B cell clones would then be screened fo ...
characterization of adult and embryonic stem cell proliferation
... of the system (e.g., the hematopoitic and nervous system) or they play a role in tissue repair and regeneration (e.g., the hepatic system). Evidence also shows that adult stem cells (whose in vivo distribution is limited to their target tissues) may in vitro be capable ...
... of the system (e.g., the hematopoitic and nervous system) or they play a role in tissue repair and regeneration (e.g., the hepatic system). Evidence also shows that adult stem cells (whose in vivo distribution is limited to their target tissues) may in vitro be capable ...
Molecular Analysis of the Clavulanic Acid Regulatory Gene Isolated
... genes of the clavulanic acid pathway are within a 12kb EcoRI DNA fragment of the S. clavuligerus genome, because this fragment appears to confer production of clavulanic acid when introduced in Streptomyces lividans (25). Very little is known about the regulation of the genes of the clavulanic acid ...
... genes of the clavulanic acid pathway are within a 12kb EcoRI DNA fragment of the S. clavuligerus genome, because this fragment appears to confer production of clavulanic acid when introduced in Streptomyces lividans (25). Very little is known about the regulation of the genes of the clavulanic acid ...
Tumor Heterogeneity - Barbara Ann Karmanos Cancer Institute
... A hypothesis that narrows the apparent differences between genetic and epigenetic mechanisms was provided by Frost and Kerbel (26), who suggested that DNA hypomethylation, and the activation of otherwise repressed genes, may be the cause of tumor variant production. In support of this view are the f ...
... A hypothesis that narrows the apparent differences between genetic and epigenetic mechanisms was provided by Frost and Kerbel (26), who suggested that DNA hypomethylation, and the activation of otherwise repressed genes, may be the cause of tumor variant production. In support of this view are the f ...
Tumor Heterogeneity
... A hypothesis that narrows the apparent differences between genetic and epigenetic mechanisms was provided by Frost and Kerbel (26), who suggested that DNA hypomethylation, and the activation of otherwise repressed genes, may be the cause of tumor variant production. In support of this view are the f ...
... A hypothesis that narrows the apparent differences between genetic and epigenetic mechanisms was provided by Frost and Kerbel (26), who suggested that DNA hypomethylation, and the activation of otherwise repressed genes, may be the cause of tumor variant production. In support of this view are the f ...
Coca Cola
... Structural support and railroad tracks, which establish intracellular organization Locomotion by cellular appendages (cilia and flagella) Segregation of chromosomes during mitosis ...
... Structural support and railroad tracks, which establish intracellular organization Locomotion by cellular appendages (cilia and flagella) Segregation of chromosomes during mitosis ...
The organic anion transport inhibitor, probenecid, inhibits the
... with constant agitation. Samples (1 ml) were removed after each treatment and washed by centrifugation (1000 g, 2 min) four times with the appropriate medium (i.e. ±probenecid). Cells were then mounted on slides and observed by epifluorescence microscopy. Carrot protoplasts were also treated 1:1 (pc ...
... with constant agitation. Samples (1 ml) were removed after each treatment and washed by centrifugation (1000 g, 2 min) four times with the appropriate medium (i.e. ±probenecid). Cells were then mounted on slides and observed by epifluorescence microscopy. Carrot protoplasts were also treated 1:1 (pc ...
Cell movements during epiboly and gastrulation in
... Fig. 1. Morphogenesis during zebrafish epiboly and gastrulation. Side views of living embryos with the animal pole (AP) to the top. An outline of stage descriptions is given in Table 1. (A) Oblong stage, at the end of the midblastula period, 3.7 h. The blastoderm is a thick cap of cells occupying ab ...
... Fig. 1. Morphogenesis during zebrafish epiboly and gastrulation. Side views of living embryos with the animal pole (AP) to the top. An outline of stage descriptions is given in Table 1. (A) Oblong stage, at the end of the midblastula period, 3.7 h. The blastoderm is a thick cap of cells occupying ab ...
Identification of differentially expressed genes
... binding and catalytic activity followed by the transcription factor activity category and others are grouped in the antioxidant and transporter activities. The cellular component category was subdivided into seven groups containing 29 genes and, among these, transcripts related to the cell group wer ...
... binding and catalytic activity followed by the transcription factor activity category and others are grouped in the antioxidant and transporter activities. The cellular component category was subdivided into seven groups containing 29 genes and, among these, transcripts related to the cell group wer ...
Homeostatic maintenance of pathogen
... parasitophorous vacuole in Plasmodium falciparum infections (Cho et al., 2002; Murphy et al., 2004; Cho and Jena, 2006). Quantitative analysis of aqp1 mRNA levels and AQP1 protein expression in wild-type and tbk1-/MEFs, revealed substantially increased levels of AQP1 in TBK1-deficient cells compared ...
... parasitophorous vacuole in Plasmodium falciparum infections (Cho et al., 2002; Murphy et al., 2004; Cho and Jena, 2006). Quantitative analysis of aqp1 mRNA levels and AQP1 protein expression in wild-type and tbk1-/MEFs, revealed substantially increased levels of AQP1 in TBK1-deficient cells compared ...
Choosing the Best Kinase Assay to Meet Your Research Needs
... including ion channels, transcription factors, phosphatases and other kinases. Based on sequence analysis, the human genome encodes approximately 518 protein kinases, and approximately one-third of the proteins in a typical mammalian cell are phosphorylated (1). Protein kinases function primarily as ...
... including ion channels, transcription factors, phosphatases and other kinases. Based on sequence analysis, the human genome encodes approximately 518 protein kinases, and approximately one-third of the proteins in a typical mammalian cell are phosphorylated (1). Protein kinases function primarily as ...