Glucagon receptor recycling: role of carboxyl terminus - AJP-Cell
... mediates slower recycling through perinuclear recycling endosomes (21). -Arrestins modulate postendocytic sorting of some GPCRs, in particular recycling (16, 18, 29). The receptor’s carboxyl (COOH) terminus interacts with the cytoskeleton, which plays an important role in trafficking, signaling, an ...
... mediates slower recycling through perinuclear recycling endosomes (21). -Arrestins modulate postendocytic sorting of some GPCRs, in particular recycling (16, 18, 29). The receptor’s carboxyl (COOH) terminus interacts with the cytoskeleton, which plays an important role in trafficking, signaling, an ...
Cancer stem cells and addicted cancer cells
... divisions of tumor cells. In normal cells, genetic alterations also occur during interphase. When such alterations arise, control mechanisms induce apoptosis as a protection against cancer. In contrast, in cancer cells these alterations are tolerated due to mutations in genes such as P53 [23]. The t ...
... divisions of tumor cells. In normal cells, genetic alterations also occur during interphase. When such alterations arise, control mechanisms induce apoptosis as a protection against cancer. In contrast, in cancer cells these alterations are tolerated due to mutations in genes such as P53 [23]. The t ...
Organelle Trail - cloudfront.net
... 1. The Encyclopedia Britannica Online - http://www.school.eb.com/comptons/article-9273572 This encyclopedia article is designed for middle school students and describes many aspects of the cell. You are able to click on the various parts of the cell using the menu on the left side of the page. This ...
... 1. The Encyclopedia Britannica Online - http://www.school.eb.com/comptons/article-9273572 This encyclopedia article is designed for middle school students and describes many aspects of the cell. You are able to click on the various parts of the cell using the menu on the left side of the page. This ...
Extracellular matrix stiffness in regulation of intestinal stem cell
... A number of recent studies [Thorel et al., 2010; Kragl et al., 2009] have demonstrated that certain adult stem cells might undergo a process called transdifferentiation – a regenerative phenomenon where stem cells from one tissue transform into cells of another [What are adult stem cells?, 2012]. Th ...
... A number of recent studies [Thorel et al., 2010; Kragl et al., 2009] have demonstrated that certain adult stem cells might undergo a process called transdifferentiation – a regenerative phenomenon where stem cells from one tissue transform into cells of another [What are adult stem cells?, 2012]. Th ...
Glypican-1 Is a Vehicle for Polyamine Uptake in Mammalian Cells
... into focus (for review, see Ref. 16). We have recently shown that the glypican-1 (Gpc-1) core protein can accumulate NO as nitrosothiols in a reaction that is dependent on reduction of Cu2⫹ to Cu⫹ (17). Moreover, the HS chains of Gpc-1 contain a small amount of glucosamine units with an unsubstitute ...
... into focus (for review, see Ref. 16). We have recently shown that the glypican-1 (Gpc-1) core protein can accumulate NO as nitrosothiols in a reaction that is dependent on reduction of Cu2⫹ to Cu⫹ (17). Moreover, the HS chains of Gpc-1 contain a small amount of glucosamine units with an unsubstitute ...
Structural Influences: Cholesterol, Drug, and Proton Binding to Full
... them as a proton-selective channel and facilitator of viral budding, replacing the need for the ESCRT proteins that other viruses utilize. Here, various amino-acid-specific-labeled samples of the full-length protein were prepared and mixed, so that only interresidue 13C-13C cross peaks between two d ...
... them as a proton-selective channel and facilitator of viral budding, replacing the need for the ESCRT proteins that other viruses utilize. Here, various amino-acid-specific-labeled samples of the full-length protein were prepared and mixed, so that only interresidue 13C-13C cross peaks between two d ...
differentiation and proliferation of embryonic mast
... disperse chromatin and a narrow rim of clear basophilic cytoplasm containing several discrete alcian blue-positive granules (Figs. 3 and 7). Except for the presence of specific granules, these cells resemble the large lymphocyte described by Maximow (28). In the studies of the incorporation of thymi ...
... disperse chromatin and a narrow rim of clear basophilic cytoplasm containing several discrete alcian blue-positive granules (Figs. 3 and 7). Except for the presence of specific granules, these cells resemble the large lymphocyte described by Maximow (28). In the studies of the incorporation of thymi ...
The Bacterial Phosphotransferase System: Structure, Function
... and HPr (heat-stable, histidine-phosphorylatable protein). The discovery of this system provided an explanation for pleiotropic carbohydrate-negative mutants of E. coli described as early as 1949 (Doudoroff et al., 1949). In 1964, the three recognized activities of the PTS were presumed to correspon ...
... and HPr (heat-stable, histidine-phosphorylatable protein). The discovery of this system provided an explanation for pleiotropic carbohydrate-negative mutants of E. coli described as early as 1949 (Doudoroff et al., 1949). In 1964, the three recognized activities of the PTS were presumed to correspon ...
y. Cell Set. Suppl. ¡1, 1-11 (1989) Printed in
... mitochondria might occur through regions in which the two membranes are in close apposition (Kellem s et al. 1975; Schwaiger et al. 1987). However, these sites had not been separated from isolated inner and outer membranes. In order to selectively mark these import sites for subsequent isolation, we ...
... mitochondria might occur through regions in which the two membranes are in close apposition (Kellem s et al. 1975; Schwaiger et al. 1987). However, these sites had not been separated from isolated inner and outer membranes. In order to selectively mark these import sites for subsequent isolation, we ...
LIGHT MICROSCOPIC STUDY OF PORELLA PLATYPHYLLA (L
... sample), subsequent rehydration, freezing at -18 and -80°C, heat treatment at 40, 50 and 100°C (for 5 and 10 min), osmotic and salt stress (0.5 M NaCl, 1 M KSCN, 25% PEG8000) were applied. In the course of monitoring the various stress factors the use of neutral red (at pH 7.6) staining proved to be ...
... sample), subsequent rehydration, freezing at -18 and -80°C, heat treatment at 40, 50 and 100°C (for 5 and 10 min), osmotic and salt stress (0.5 M NaCl, 1 M KSCN, 25% PEG8000) were applied. In the course of monitoring the various stress factors the use of neutral red (at pH 7.6) staining proved to be ...
Datasheet - Creative Diagnostics
... Mycoplasma genitalium is a small parasitic bacterium that lives on the ciliated epithelial cells of the primate genital and respiratory tracts. M. genitalium is the smallest known genome that can constitute a cell, and the second-smallest bacterium after the endosymbiont Carsonella ruddii. Until the ...
... Mycoplasma genitalium is a small parasitic bacterium that lives on the ciliated epithelial cells of the primate genital and respiratory tracts. M. genitalium is the smallest known genome that can constitute a cell, and the second-smallest bacterium after the endosymbiont Carsonella ruddii. Until the ...
Histological and ultrastructural analysis of the
... have more plantations than others, they produce in less tons per year, their productivity is lower. In the Latim America, the Brazil has 479,614 hectares of Banana plantations producing 6,783,460 t and is overtaken by Ecuador that with half the area planted is able to produce 7,637,320 t (FreshPlaza ...
... have more plantations than others, they produce in less tons per year, their productivity is lower. In the Latim America, the Brazil has 479,614 hectares of Banana plantations producing 6,783,460 t and is overtaken by Ecuador that with half the area planted is able to produce 7,637,320 t (FreshPlaza ...
Limbal stem cell deficiency and its management
... 5) The regulation of cultured limbal epithelial cell therapy The culture expansion of human limbal epithelium and its clinical application as part of a clinical trial is highly regulated (for example EMA and MHRA). The actual culture process has to be performed in accordance with good manufacturing ...
... 5) The regulation of cultured limbal epithelial cell therapy The culture expansion of human limbal epithelium and its clinical application as part of a clinical trial is highly regulated (for example EMA and MHRA). The actual culture process has to be performed in accordance with good manufacturing ...
Nonviral gene transfer to skeletal, smooth, and cardiac muscle in
... downregulation (49), DNA methylation (50), immune responses generated against the produced transgene (49, 61), or inflammatory responses against CpG motifs in the plasmids (130, 136). It should also be stressed that the levels and duration of expression are also dependent on the transgene product be ...
... downregulation (49), DNA methylation (50), immune responses generated against the produced transgene (49, 61), or inflammatory responses against CpG motifs in the plasmids (130, 136). It should also be stressed that the levels and duration of expression are also dependent on the transgene product be ...
... has enzyme activity, the sigma factor contains most promoter recognition determinants and confers promoter specificity to the RNA polymerase. The sigma factor is also required for transcription initiation, which is a stepwise process. First, the RNAP holoenzyme forms a closed complex around the prom ...
Production of macrophage activating factors by the mitogen
... with or without stimulated cell supernatants. Then, the phagocytic activity against inactivated yeast and peroxidase production were measured. Stimulated cell supernatants increased the phagocytic activity and the peroxidase production of allogenic peritoneal macrophages. The activities of these sti ...
... with or without stimulated cell supernatants. Then, the phagocytic activity against inactivated yeast and peroxidase production were measured. Stimulated cell supernatants increased the phagocytic activity and the peroxidase production of allogenic peritoneal macrophages. The activities of these sti ...
Slide 1
... • Ribosomes on the surface of the rough ER – Produce proteins that are secreted, inserted into membranes, or transported in vesicles to other organelles ...
... • Ribosomes on the surface of the rough ER – Produce proteins that are secreted, inserted into membranes, or transported in vesicles to other organelles ...
microbiology-1st-edition-wessner-test-bank
... cell wall, and the functions of these structures. Section Reference: Section 2.4 The cell envelope 19) What conditions must be met in order for an “active transport system” to transport of a nutrient into a cell? a) The nutrient concentration must be higher on the outside of the cell. b) The nutrien ...
... cell wall, and the functions of these structures. Section Reference: Section 2.4 The cell envelope 19) What conditions must be met in order for an “active transport system” to transport of a nutrient into a cell? a) The nutrient concentration must be higher on the outside of the cell. b) The nutrien ...
STUDIES ON LYSOSOMES XI. Characterization of a Hydrolase
... yielded the same final concentrations as described in the original method. The optical density was read at 660 m/, and the enzyme activity was indicated as micromoles phosphorus released from substrate per milligram protein per hour. Acid ribonuclease activity was also assayed. Initial attempts to a ...
... yielded the same final concentrations as described in the original method. The optical density was read at 660 m/, and the enzyme activity was indicated as micromoles phosphorus released from substrate per milligram protein per hour. Acid ribonuclease activity was also assayed. Initial attempts to a ...
... whose phenotypic effects relate to suppression of their intended targets. By summarizing only such reagent effects for each gene, ATARiS produces quantitative, gene-level phenotype values, which provide an intuitive measure of the effect of gene suppression in each sample. This method is robust for ...
Targeting Infectious Disease: Structural and functional
... (ORFs), six of which are common to all coronaviruses (Figure 1). The first two, 1a and 1b, constitute the replicase gene. The other four, S, E, M and N, encode structural proteins that make up the capsid or associate with the genomic RNA. The genome also contains a variable number of accessory prote ...
... (ORFs), six of which are common to all coronaviruses (Figure 1). The first two, 1a and 1b, constitute the replicase gene. The other four, S, E, M and N, encode structural proteins that make up the capsid or associate with the genomic RNA. The genome also contains a variable number of accessory prote ...
Confocal imaging of glial cells in the intact rat optic nerve
... in a single two-dimensional image. 3) Cell images can be rotated through 360" in all planes to provide a new perspective of glial cell structure in the intact tissue. 4) Reconstruction of optical sections, within a narrow focal plane, provides a high definition and resolution of the finer details of ...
... in a single two-dimensional image. 3) Cell images can be rotated through 360" in all planes to provide a new perspective of glial cell structure in the intact tissue. 4) Reconstruction of optical sections, within a narrow focal plane, provides a high definition and resolution of the finer details of ...
Transgenic rats carrying copies of the human c-Ha
... exhibit invasion of the muscle layer (15). The reasons for such recurrence and invasive characteristics have not yet been elucidated in detail. Therefore, it is important to establish appropriate animal models featuring highly malignant superficial type carcinomas as observed in human cases. The ras ...
... exhibit invasion of the muscle layer (15). The reasons for such recurrence and invasive characteristics have not yet been elucidated in detail. Therefore, it is important to establish appropriate animal models featuring highly malignant superficial type carcinomas as observed in human cases. The ras ...
Journal of the Minority Science Apprentice
... many components that can be affected by neoplasm, more commonly known as cancerous conditions. In regard to skin of color, specifically of those of African American descent, there are three pertinent nonmelanoma cancerous conditions that are seen, which include Cutaneous T-Cell Lymphoma (CTCL) and B ...
... many components that can be affected by neoplasm, more commonly known as cancerous conditions. In regard to skin of color, specifically of those of African American descent, there are three pertinent nonmelanoma cancerous conditions that are seen, which include Cutaneous T-Cell Lymphoma (CTCL) and B ...