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pensum for kjb 491-1997
pensum for kjb 491-1997

... Mechanisms of autophagosome biogenesis (Rubinsztein, D.C., Shpilka, T., and Elazar, Z. Current Biology 22 (2012) R29-R34 (5 pages)). Endosomal coat proteins and sorting Structures and mechanisms of vesicle coat components and multisubunit tethering complexes (Jackson, L.P., Kümmel, D., Reinisch, K. ...
Biology: Cells the Fundamental Unit of Life
Biology: Cells the Fundamental Unit of Life

... This series of lessons is meant to introduce students to the functions of a cell and the basic components of cells. It uses several instructional approaches that are meant to engage students in the process of understanding this complex and exciting material. In order to understand the basic function ...
Chapter 7 Cellular Structure and Function HUMAN SKIN HUMAN
Chapter 7 Cellular Structure and Function HUMAN SKIN HUMAN

... For centuries, scientists had no idea that the human body consists of tril–lions of cells. Cells are so small that their existence was unknown before the invention of the microscope. In 1665, as indicated in Figure 7.1, an English scientist named Robert Hooke made a simple microscope and looked at a ...
MB207_10 - MB207Jan2010
MB207_10 - MB207Jan2010

... Hydrophobic regions are embedded within the membrane interior in a way that makes these molecules difficult to remove from membrane. Hydrophilic regions that extend outward from the membrane into an aqueous phase on one or both sides of the membrane. Protruding from one side of the bilayer: integral ...
Biogenesis of photosynthetic complexes in the chloroplast of
Biogenesis of photosynthetic complexes in the chloroplast of

... genome deletion caused by the insertion is marked by the dashed line. Arrows indicate primers used in (b) and (c). Also the pSL18 cassette itself underwent some rearrangements, including head-to-tail concatamerization and deletion of 899 bp close to the flanking border (dashed line). (b) Polymerase ...
Modelling the structural response of an eukaryotic cell in the optical
Modelling the structural response of an eukaryotic cell in the optical

Hippocampus
Hippocampus

... to consist of a series of transversaly oriented excitatory pathways that begins with a projection from the entorhinal cortex (EC) to the dentate gyrus (the perforant pathway), continues with the mossy fiber pathway from the dentate gyrus (DG) to field CA3, and ends with the Schaffer collaterals from ...
Foundations - Cells, organelles and cell boundaries
Foundations - Cells, organelles and cell boundaries

The Plant Cell - Gunawardena Lab
The Plant Cell - Gunawardena Lab

Chapter 8: Cellular Transport and the Cell Cycle
Chapter 8: Cellular Transport and the Cell Cycle

... CELL GROWTH AND REPRODUCTION ...
1. Plasmid structure 2. Plasmid replication and copy
1. Plasmid structure 2. Plasmid replication and copy

Feb 25 lecture presentation
Feb 25 lecture presentation

... 5. Plasmid segregation is maintained by a par locus-a partition locus that ensures each daughter cells gets on plasmid. Not all plasmids have such sequences. 6. There are 5 main “incompatibility” groups of plasmid replication. Not all plasmids can live with each other. 7. Agents that disrupt DNA rep ...
molecular cloning and expression of the proliferating cell nuclear
molecular cloning and expression of the proliferating cell nuclear

... sequence confirmed its identity as the shorter form of pcna (Pcpcna2) containing an authentic poly-A tail. Use of primers PLPCNA5F/PLPCNA6R and PLPCNA5F/PLPCNA7R with genomic DNA as templates also yielded two DNA fragments that were substantially longer than their corresponding cDNA fragments (Fig. ...
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08 Prokaryotes

... Cell wall function Maintain the cell shape Protect the cell Prevent the cell from bursting in hypotonic environment Differ in chemical composition and construction from the cell walls of protists, fungi, and plants. ...
Yantar, a conserved arginine-rich protein is involved in Drosophila
Yantar, a conserved arginine-rich protein is involved in Drosophila

... tumor phenotype, and we named their corresponding genes yantar (ytr), polka dots (pkdt), and splotchy (splo). Hemocytes from these mutants were visualized after immunostaining using two hemocyte-specific monoclonal antibodies, MAb H2 and L1. MAb H2 recognizes the hemese antigen present in all Drosop ...
Origin of diderm (Gram-negative) bacteria
Origin of diderm (Gram-negative) bacteria

... or two membranes (diderms). It is important to understand how these and other variations that are observed in the cell envelopes of prokaryotic organisms have originated. In 2009, James Lake proposed that cells with two membranes (primarily Gramnegative bacteria) originated from an ancient endosymbi ...
Coordinated Regulation of AIB1 Transcriptional Activity by
Coordinated Regulation of AIB1 Transcriptional Activity by

... AIB1 Is Modified by SUMO-1—Sumoylation has recently been identified as an important mechanism that regulates protein functions in essential biological processes, such as gene transcription, subnuclear structure organization, and cell cycle progression. Within the SRC family of coactivators, both GRI ...
Bacterial ancestry of actin and tubulin Fusinita van den Ent, Linda
Bacterial ancestry of actin and tubulin Fusinita van den Ent, Linda

... the spacing between the MreB subunits along the filament (51 Å) is reminiscent of the spacing between the subunits in filamentous actin (55 Å) (Figure 2). Also, the threedimensional structure of MreB and actin are very similar [39••]. There is, however, one interesting difference between MreB and ac ...
activator
activator

... DNA Methylation • DNA methylation, the addition of methyl groups to certain bases in DNA, is associated with reduced transcription in some species • DNA methylation can cause long-term inactivation of genes in cellular differentiation ...
- Wiley Online Library
- Wiley Online Library

... To complement the genetic and genomic resources that exist for this species, we generated fluorescent protein fusions that label the nucleus, endoplasmic reticulum, Golgi apparatus, trans-Golgi network, plasma membrane, apoplast, late endosome/multivesicular bodies (MVB), transitory late endosome/ t ...
The archaeal origins of the eukaryotic translational system
The archaeal origins of the eukaryotic translational system

... comparative analysis of these and other eukaryotic features among the three different cellular phylodomains supports the idea that an archaeal translational system was most likely incorporated by means of endosymbiosis into a host cell that was neither bacterial nor archaeal in any modern sense. Phy ...
Bacteria
Bacteria

Chapter 3 PowerPoint
Chapter 3 PowerPoint

... Several organelles are involved in making and processing proteins. (continued) • Ribosomes link amino acids to form proteins. • Golgi Apparatus- process, sort & deliver proteins • Vesicles are membrane-bound sacs that hold materials until it is ready for use. ...
CHAPTER 35: PROTISTS
CHAPTER 35: PROTISTS

3 - Rudner Lab - Harvard University
3 - Rudner Lab - Harvard University

... is tied to the assembly of a critically important structure in development. The translation of genetic information into form during development is guided by a complex interplay between genes and their protein products. Morphogenesis in systems ranging in complexity from bacteria to the mammalian emb ...
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Cell nucleus



In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel) is a membrane-enclosed organelle found in eukaryotic cells. Eukaryotes usually have a single nucleus, but a few cell types have no nuclei, and a few others have many.Cell nuclei contain most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these chromosomes are the cell's nuclear genome. The function of the nucleus is to maintain the integrity of these genes and to control the activities of the cell by regulating gene expression—the nucleus is, therefore, the control center of the cell. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm, and the nucleoskeleton (which includes nuclear lamina), a network within the nucleus that adds mechanical support, much like the cytoskeleton, which supports the cell as a whole.Because the nuclear membrane is impermeable to large molecules, nuclear pores are required that regulate nuclear transport of molecules across the envelope. The pores cross both nuclear membranes, providing a channel through which larger molecules must be actively transported by carrier proteins while allowing free movement of small molecules and ions. Movement of large molecules such as proteins and RNA through the pores is required for both gene expression and the maintenance of chromosomes. The interior of the nucleus does not contain any membrane-bound sub compartments, its contents are not uniform, and a number of sub-nuclear bodies exist, made up of unique proteins, RNA molecules, and particular parts of the chromosomes. The best-known of these is the nucleolus, which is mainly involved in the assembly of ribosomes. After being produced in the nucleolus, ribosomes are exported to the cytoplasm where they translate mRNA.
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