Profilin association with monomeric actin in
... antibodies bind in the cytoplasm and to regions of plasma membrane free of actin filaments in leukocytes and stimulated platelets (Hartwig et al., 1989). Polyphosphoinositides may mediate this binding to membranes (Lassing and Lindberg, 1985), but the fraction of profilin bound to membranes has not ...
... antibodies bind in the cytoplasm and to regions of plasma membrane free of actin filaments in leukocytes and stimulated platelets (Hartwig et al., 1989). Polyphosphoinositides may mediate this binding to membranes (Lassing and Lindberg, 1985), but the fraction of profilin bound to membranes has not ...
Mitochondrial trafficking and anchoring in neurons
... Correspondence to Zu-Hang Sheng: [email protected] Abbreviations used in this paper: KIF5, kinesin-1 family; MT, microtubule. ...
... Correspondence to Zu-Hang Sheng: [email protected] Abbreviations used in this paper: KIF5, kinesin-1 family; MT, microtubule. ...
Triglyceride-Rich Lipoproteins as Agents of Innate Immunity
... It has been recognized for 120 years that the interaction between LPS and lipoproteins is dependent on plasma factors [8, 13]. Although several plasma proteins can interact with LPS, none have been more extensively studied than CD14 [18] and the acute-phase reactant LPS-binding protein (LBP) [19, 20 ...
... It has been recognized for 120 years that the interaction between LPS and lipoproteins is dependent on plasma factors [8, 13]. Although several plasma proteins can interact with LPS, none have been more extensively studied than CD14 [18] and the acute-phase reactant LPS-binding protein (LBP) [19, 20 ...
lysis strategy of streptococcus pneumoniae bacteriophages
... lysin by the same experimental procedures after culture treatment with the Sec inhibitor sodium azide. It was found that the phage lytic enzyme is possibly exported by the Sec system of pneumococci in spite of the striking absence of a signal sequence that could target it to the extracytoplasmic env ...
... lysin by the same experimental procedures after culture treatment with the Sec inhibitor sodium azide. It was found that the phage lytic enzyme is possibly exported by the Sec system of pneumococci in spite of the striking absence of a signal sequence that could target it to the extracytoplasmic env ...
Homologous pairing and the role of pairing centers in meiosis
... Homologous pairing and the telomere bouquet Before homologous chromosomes recombine and form a bivalent, they must find each other within the cell nucleus. In most organisms, the initiation of homologous pairing occurs at numerous sites along chromosomes by a mechanism that still remains unclear. Th ...
... Homologous pairing and the telomere bouquet Before homologous chromosomes recombine and form a bivalent, they must find each other within the cell nucleus. In most organisms, the initiation of homologous pairing occurs at numerous sites along chromosomes by a mechanism that still remains unclear. Th ...
Partial Purifiaction of β-1,3-glucan synthases and
... Recent studies of different β-1,3-glucans have identified the pharmacological activities of paramylon, a Euglena derived β-1,3-glucan. Although paramylon has relatively low immune-stimulating activities, chemical modification of the paramylon granule increased immune-potentiation with specific antim ...
... Recent studies of different β-1,3-glucans have identified the pharmacological activities of paramylon, a Euglena derived β-1,3-glucan. Although paramylon has relatively low immune-stimulating activities, chemical modification of the paramylon granule increased immune-potentiation with specific antim ...
Type XIII collagen. Structural and functional characterization of the
... trimerization of type XIII collagen chains was initiated by 21 amino acid residues adjacent to the transmembrane domain on the extracellular side, and this sequence was found to be conserved in several other collagenous transmembrane proteins. In addition to the transmembrane form, the ectodomain of ...
... trimerization of type XIII collagen chains was initiated by 21 amino acid residues adjacent to the transmembrane domain on the extracellular side, and this sequence was found to be conserved in several other collagenous transmembrane proteins. In addition to the transmembrane form, the ectodomain of ...
Phloem transport: a review of mechanisms and
... shorter, overlapping sieve tubes with apoplastic loading steps between them. Lang (1979) called these intervening loading steps ‘relays’. In this relay system, solutes are energetically transported from one unit to the next, providing a boost in pressure at the relays along the transport pathway. Th ...
... shorter, overlapping sieve tubes with apoplastic loading steps between them. Lang (1979) called these intervening loading steps ‘relays’. In this relay system, solutes are energetically transported from one unit to the next, providing a boost in pressure at the relays along the transport pathway. Th ...
The ultrastructure of a doliolid and a copepod
... The goal of this study was to determine the morphology and ultrastructure of doliolid pellets using light, epifluorescence and transmission electron microscopy and compare the results to observations of calanoid copepod pellets. For (ultra)structural analyses, pellets of gonozooids of Dolioletta geg ...
... The goal of this study was to determine the morphology and ultrastructure of doliolid pellets using light, epifluorescence and transmission electron microscopy and compare the results to observations of calanoid copepod pellets. For (ultra)structural analyses, pellets of gonozooids of Dolioletta geg ...
Phloem transport: A review of mechanisms and controls (PDF
... shorter, overlapping sieve tubes with apoplastic loading steps between them. Lang (1979) called these intervening loading steps ‘relays’. In this relay system, solutes are energetically transported from one unit to the next, providing a boost in pressure at the relays along the transport pathway. Th ...
... shorter, overlapping sieve tubes with apoplastic loading steps between them. Lang (1979) called these intervening loading steps ‘relays’. In this relay system, solutes are energetically transported from one unit to the next, providing a boost in pressure at the relays along the transport pathway. Th ...
Therapeutic targeting of autophagy in neurodegenerative and
... which evolve into double-membraned, sacshaped structures. After the edges of the phagophores extend and fuse, engulfing a portion of cytoplasm, they become known as autophagosomes. These are then trafficked along microtubules in a direction that is biased toward the perinuclear microtubule-organizin ...
... which evolve into double-membraned, sacshaped structures. After the edges of the phagophores extend and fuse, engulfing a portion of cytoplasm, they become known as autophagosomes. These are then trafficked along microtubules in a direction that is biased toward the perinuclear microtubule-organizin ...
Exosomes: Implications in HIV-1 Pathogenesis
... classes of EV include (I) apoptotic bodies that are generated by plasma membrane blebbing during cell death and (II) microvesicles [also known as microparticles or ectosomes] that are assembled at and are released from eukaryotic cellular plasma membranes via ectocytosis. Comparative analyses of var ...
... classes of EV include (I) apoptotic bodies that are generated by plasma membrane blebbing during cell death and (II) microvesicles [also known as microparticles or ectosomes] that are assembled at and are released from eukaryotic cellular plasma membranes via ectocytosis. Comparative analyses of var ...
PDF
... embryo mouse, targeted disruption of Wnt3a results in the loss of caudal somites and the tailbud (Takada et al., 1993). In Xenopus embryos, antagonism of Wnt signaling allows the formation of anterior structures at the expense of posterior ones (Leyns et al., 1997; Glinka et al., 1998). This is also ...
... embryo mouse, targeted disruption of Wnt3a results in the loss of caudal somites and the tailbud (Takada et al., 1993). In Xenopus embryos, antagonism of Wnt signaling allows the formation of anterior structures at the expense of posterior ones (Leyns et al., 1997; Glinka et al., 1998). This is also ...
Focusing on unpolymerized actin.
... while the total concentration of polymerized actin remains roughly constant. Net polymerization occurs primarily at the cell front and net depolymerization occurs, depending on cell type, throughout or at the rear of the lamella (Wang, 1985; Symons and Mitchison, 1991; Theriot and Mitchison, 1992; Z ...
... while the total concentration of polymerized actin remains roughly constant. Net polymerization occurs primarily at the cell front and net depolymerization occurs, depending on cell type, throughout or at the rear of the lamella (Wang, 1985; Symons and Mitchison, 1991; Theriot and Mitchison, 1992; Z ...
AcmA of Lactococcus lactis is an N-acetylglucosaminidase
... containing either pGK13, not encoding AcmA (2), pGKAL1, encoding enzyme A3 (3), pGKAL3, encoding enzyme A2 (4), pGKAL4, encoding enzyme A1 (5), pGKAL5, encoding enzyme A0 (6), pGKAL6, encoding enzyme A1.5 (7), or pGKAL7, encoding enzyme A4 (8). Cell extracts and supernatant samples were separated in ...
... containing either pGK13, not encoding AcmA (2), pGKAL1, encoding enzyme A3 (3), pGKAL3, encoding enzyme A2 (4), pGKAL4, encoding enzyme A1 (5), pGKAL5, encoding enzyme A0 (6), pGKAL6, encoding enzyme A1.5 (7), or pGKAL7, encoding enzyme A4 (8). Cell extracts and supernatant samples were separated in ...
boron in plant structure and function
... now conclude that phloem movement of boron depends on the sugar or polyol transport molecules used by the particular plant. It could be of interest that a major crop in the United States, soybean, contains large quantities of the polyol pinitol and shows some response to foliar applications of boron ...
... now conclude that phloem movement of boron depends on the sugar or polyol transport molecules used by the particular plant. It could be of interest that a major crop in the United States, soybean, contains large quantities of the polyol pinitol and shows some response to foliar applications of boron ...
Article (Published version)
... Gli1, Gli2 and Gli3 are required for the development of primary neurons Several morpholino-modified antisense oligonucleotides (MO) were designed overlapping or adjacent to the initiator ATG of each Gli mRNA. Initial tests for efficacy of their ability to inhibit target mRNA translation used in vitr ...
... Gli1, Gli2 and Gli3 are required for the development of primary neurons Several morpholino-modified antisense oligonucleotides (MO) were designed overlapping or adjacent to the initiator ATG of each Gli mRNA. Initial tests for efficacy of their ability to inhibit target mRNA translation used in vitr ...
A PP2A-B55 recognition signal controls substrate
... It has long been known that mitotic kinases, substrates of the anaphase-promoting complex/cyclosome, and many other regulatory enzymes have specific linear recognition motifs. However, these often fail to adequately describe the behavior seen in cells, where proteins sharing similar or sometimes ide ...
... It has long been known that mitotic kinases, substrates of the anaphase-promoting complex/cyclosome, and many other regulatory enzymes have specific linear recognition motifs. However, these often fail to adequately describe the behavior seen in cells, where proteins sharing similar or sometimes ide ...
Cell Calcium Viral calciomics: Interplays between Ca2+ and virus
... Fig. 2. Virus infection selectively perturbs pro-apoptotic and pro-survival ER-mitochondria Ca2+ signaling. Upon engagement of receptors, the production of IP3 leads to the activation of IP3 R and release of Ca2+ from internal store. The decrease of ER Ca2+ concentration is subsequently sensed by th ...
... Fig. 2. Virus infection selectively perturbs pro-apoptotic and pro-survival ER-mitochondria Ca2+ signaling. Upon engagement of receptors, the production of IP3 leads to the activation of IP3 R and release of Ca2+ from internal store. The decrease of ER Ca2+ concentration is subsequently sensed by th ...
Cdc6 in S phase in human cells - Journal of Cell Science
... implying that in late G1, nuclear protein export does not control nuclear Cdc6 levels. However, as a number of soluble export factors can be lost from isolated nuclei (Kehlenbach et al., 1998) it is likely that nuclear protein export does not function optimally in our system. This has allowed identi ...
... implying that in late G1, nuclear protein export does not control nuclear Cdc6 levels. However, as a number of soluble export factors can be lost from isolated nuclei (Kehlenbach et al., 1998) it is likely that nuclear protein export does not function optimally in our system. This has allowed identi ...
Mitochondrial dynamics, mitophagy and cardiovascular disease
... & Chan, 2005; Chan, 2006). Additionally, MFN2 has been implicated in several other physiological functions, such as modulation of energetic processes, endoplasmic reticulum–mitochondria coupling, and regulation of mitophagy, a process through which mitochondria are engulfed by autophagosomes and del ...
... & Chan, 2005; Chan, 2006). Additionally, MFN2 has been implicated in several other physiological functions, such as modulation of energetic processes, endoplasmic reticulum–mitochondria coupling, and regulation of mitophagy, a process through which mitochondria are engulfed by autophagosomes and del ...
`Sarcomeres` of smooth muscle - Journal of Cell Science
... Morphometric and statistical analysis Sampling and analysis were carried out ‘blind’. The codes indicating experimental conditions were revealed only after the analysis of each group was finished. Specialized image analysis software (Image Pro-Plus 3.0) was used to help with the manual counting of t ...
... Morphometric and statistical analysis Sampling and analysis were carried out ‘blind’. The codes indicating experimental conditions were revealed only after the analysis of each group was finished. Specialized image analysis software (Image Pro-Plus 3.0) was used to help with the manual counting of t ...