Axonal of Kinesin in the Chain Isoforms
... hexokinase. These results suggest that KHC-A is enriched on small tubulovesicular structures like synaptic vesicles and that at least one form of KHC-B is predominantly on mitochondria. Biochemical specialization may target kinesins to appropriate organelles and facilitate differential regulation of ...
... hexokinase. These results suggest that KHC-A is enriched on small tubulovesicular structures like synaptic vesicles and that at least one form of KHC-B is predominantly on mitochondria. Biochemical specialization may target kinesins to appropriate organelles and facilitate differential regulation of ...
Zinc transporters that regulate vacuolar zinc storage in
... which belong to the ZIP family of metal transporters. Under zinc limitation, ZRT1 and ZRT2 transcription is induced by the Zap1p transcriptional activator. We describe here a new component of zinc homeostasis, vacuolar zinc storage, that is also regulated by Zap1p. Zinc-replete cells accumulate zinc ...
... which belong to the ZIP family of metal transporters. Under zinc limitation, ZRT1 and ZRT2 transcription is induced by the Zap1p transcriptional activator. We describe here a new component of zinc homeostasis, vacuolar zinc storage, that is also regulated by Zap1p. Zinc-replete cells accumulate zinc ...
SURGERY OF THE LACRIMAL DRAINAGE SYSTEM
... elevator, moving towards the sharp lacrimal crest and then down into the lacrimal fossa, still separating the periosteum from the bone.Take great care to keep the periosteal elevator always just under the periosteum and right on the surface of the bone. The lacrimal crest can have quite a sharp angl ...
... elevator, moving towards the sharp lacrimal crest and then down into the lacrimal fossa, still separating the periosteum from the bone.Take great care to keep the periosteal elevator always just under the periosteum and right on the surface of the bone. The lacrimal crest can have quite a sharp angl ...
Three distinct ribosome assemblies modulated by translation are the
... Here we took advantage of atomic force microscopy (AFM), which has the unique capacity to resolve both single RNA molecules (Hansma et al., 2004) and ribosomes (Yoshida et al., 1997; Mikamo et al., 2005; Mikamo-Satoh et al., 2009). Highlight results from AFM imaging include the visualization of sing ...
... Here we took advantage of atomic force microscopy (AFM), which has the unique capacity to resolve both single RNA molecules (Hansma et al., 2004) and ribosomes (Yoshida et al., 1997; Mikamo et al., 2005; Mikamo-Satoh et al., 2009). Highlight results from AFM imaging include the visualization of sing ...
Effect of bile salts on the DNA and membrane integrity of enteric
... pathogenic potential of an enteric bacterium is directly related to its ability to grow in the presence of bile salts. However, to determine if this hypothesis is true the mechanisms by which bacteria are able to grow in bile salt environments need to be ...
... pathogenic potential of an enteric bacterium is directly related to its ability to grow in the presence of bile salts. However, to determine if this hypothesis is true the mechanisms by which bacteria are able to grow in bile salt environments need to be ...
Cell cycle checkpoints in Caenorhabditis elegans
... Figure 24. par-5 is necessary for IR-induced response. .......................................................... 58 Figure 25. par-2, par-3 and mpk-1 are dispensable for the S-phase checkpoint. .................... 60 Figure 26. par-5 is required for replication stress-induced cell cycle delay in t ...
... Figure 24. par-5 is necessary for IR-induced response. .......................................................... 58 Figure 25. par-2, par-3 and mpk-1 are dispensable for the S-phase checkpoint. .................... 60 Figure 26. par-5 is required for replication stress-induced cell cycle delay in t ...
Airway surface liquid pH in well-differentiated airway - AJP-Cell
... In some experiments, amiloride (10 mg/kg of 1 mM solution) was injected intraperitoneally 30 min before anesthesia, and 2.7 g of amiloride (dispersed in perfluorocarbon) was instilled into trachea together with BCECF-dextran. ASL pH was measured 10 min after the perfluorocarbon instillation. Mice w ...
... In some experiments, amiloride (10 mg/kg of 1 mM solution) was injected intraperitoneally 30 min before anesthesia, and 2.7 g of amiloride (dispersed in perfluorocarbon) was instilled into trachea together with BCECF-dextran. ASL pH was measured 10 min after the perfluorocarbon instillation. Mice w ...
Control of Pre-mRNA Splicing by the General Splicing Factors
... to the importance of splicing for normal cellular function. The splicing process is made more complex by the fact that many premRNAs can be spliced in more than one way to give mature transcripts coding for proteins with distinct functions. Such alternative splicing greatly expands the coding capaci ...
... to the importance of splicing for normal cellular function. The splicing process is made more complex by the fact that many premRNAs can be spliced in more than one way to give mature transcripts coding for proteins with distinct functions. Such alternative splicing greatly expands the coding capaci ...
Direct Interaction between Survivin and Smac/DIABLO Is Essential
... vitro and does not inhibit caspase-3 activity. Wang and colleagues identified a novel mitochondrial-associated protein Smac/DIABLO that was able to interact with IAPs (20, 21) and may help explain the inhibitory function of Survivin. Smac/DIABLO is a mitochondria protein but is released into the cyt ...
... vitro and does not inhibit caspase-3 activity. Wang and colleagues identified a novel mitochondrial-associated protein Smac/DIABLO that was able to interact with IAPs (20, 21) and may help explain the inhibitory function of Survivin. Smac/DIABLO is a mitochondria protein but is released into the cyt ...
mexCD-oprJ aeruginosa
... Figure 4-6: NfxB and EsrC interact in the presence and absence of CHX-mediated envelope stress .........61 Figure 4-7: Screening for NfxB variants demonstrating a loss of interaction with EsrC .............................63 Figure 4-8: Expression of EsrC and mutant NfxB proteins in E. coli ...
... Figure 4-6: NfxB and EsrC interact in the presence and absence of CHX-mediated envelope stress .........61 Figure 4-7: Screening for NfxB variants demonstrating a loss of interaction with EsrC .............................63 Figure 4-8: Expression of EsrC and mutant NfxB proteins in E. coli ...
- Wiley Online Library
... involves self-limiting gastrointestinal symptoms in otherwise healthy individuals but can also develop into more systemic conditions, primarily affecting the brain as well as the fetus in pregnant women (Allerberger and Wagner, 2010). In such severe invasive cases, mortality rates of up to 30% have ...
... involves self-limiting gastrointestinal symptoms in otherwise healthy individuals but can also develop into more systemic conditions, primarily affecting the brain as well as the fetus in pregnant women (Allerberger and Wagner, 2010). In such severe invasive cases, mortality rates of up to 30% have ...
Auxin coordinates cell division and cell fate specification during
... In the above paragraphs we referred to some of the possible signalling pathways that could link auxin to the molecular regulation of cell cycle. However, on top of this complexity, it could be that some auxin responses are confined to certain stages of the cell cycle or in other words that cells mig ...
... In the above paragraphs we referred to some of the possible signalling pathways that could link auxin to the molecular regulation of cell cycle. However, on top of this complexity, it could be that some auxin responses are confined to certain stages of the cell cycle or in other words that cells mig ...
Auxin coordinates cell division and cell fate specification during
... In the above paragraphs we referred to some of the possible signalling pathways that could link auxin to the molecular regulation of cell cycle. However, on top of this complexity, it could be that some auxin responses are confined to certain stages of the cell cycle or in other words that cells mig ...
... In the above paragraphs we referred to some of the possible signalling pathways that could link auxin to the molecular regulation of cell cycle. However, on top of this complexity, it could be that some auxin responses are confined to certain stages of the cell cycle or in other words that cells mig ...
Self-Incompatibility-induced Programmed Cell
... Dangl, 1996; van Doorn, 2011; van Doorn et al., 2011). There is considerable biochemical evidence for the involvement of caspase-like activities in plant PCD (van Doorn and Woltering, 2005). For example, Vacuolar Processing Enzyme (VPE) has YVADase (caspase-1-like) activity (Hatsugai et al., 2004; R ...
... Dangl, 1996; van Doorn, 2011; van Doorn et al., 2011). There is considerable biochemical evidence for the involvement of caspase-like activities in plant PCD (van Doorn and Woltering, 2005). For example, Vacuolar Processing Enzyme (VPE) has YVADase (caspase-1-like) activity (Hatsugai et al., 2004; R ...
CE - University of Pittsburgh
... • HDL may transfer some cholesterol esters to other lipoproteins. • Some remain associated with HDL, which may be taken up by liver & degraded. • HDL thus transports cholesterol from tissues & other lipoproteins to the liver, which can excrete excess cholesterol as bile acids. • High blood levels of ...
... • HDL may transfer some cholesterol esters to other lipoproteins. • Some remain associated with HDL, which may be taken up by liver & degraded. • HDL thus transports cholesterol from tissues & other lipoproteins to the liver, which can excrete excess cholesterol as bile acids. • High blood levels of ...
Downloaded - The Journal of Cell Biology
... cell migration and axon outgrowth (for review see Anastasiadis and Reynolds, 2000). The JM region may modulate adhesion by serving as the binding site for regulatory proteins. One candidate, p120ctn (henceforth p120), was identified by scientists studying the effects on cell adhesion of the oncogeni ...
... cell migration and axon outgrowth (for review see Anastasiadis and Reynolds, 2000). The JM region may modulate adhesion by serving as the binding site for regulatory proteins. One candidate, p120ctn (henceforth p120), was identified by scientists studying the effects on cell adhesion of the oncogeni ...
Auxin transport routes in plant development
... Other proteins that play a role in auxin efflux are plant orthologs of the mammalian ATP-binding cassette subfamily B (ABCB)-type transporters of the multidrug resistance/phosphoglycoprotein (ABCB/MDR/PGP) protein family (Noh et al., 2001; Verrier et al., 2008). Some of these (ABCB1, ABCB4 and ABCB1 ...
... Other proteins that play a role in auxin efflux are plant orthologs of the mammalian ATP-binding cassette subfamily B (ABCB)-type transporters of the multidrug resistance/phosphoglycoprotein (ABCB/MDR/PGP) protein family (Noh et al., 2001; Verrier et al., 2008). Some of these (ABCB1, ABCB4 and ABCB1 ...
Schubert, C. M., R. Lin, C. J. de Vries, R. H. A.
... genes can disrupt the localization of all PAR proteins (Etemad-Moghadam et al., 1995; Boyd et al., 1996; Tabuse et al., 1998; Hung and Kemphues, 1999). Mutations in the par genes also cause marked defects in many, or all, of the subsequent asymmetries observed between wild-type blastomeres after cel ...
... genes can disrupt the localization of all PAR proteins (Etemad-Moghadam et al., 1995; Boyd et al., 1996; Tabuse et al., 1998; Hung and Kemphues, 1999). Mutations in the par genes also cause marked defects in many, or all, of the subsequent asymmetries observed between wild-type blastomeres after cel ...
Plant hormones and growth regulators
... growth, whereas reducing its concentration promoted cell and tissue elongation (Bennet-Clark, 1956 ; Tagawa and Bonner, 1957 ). Strong support for the Ca2+/pectate interaction came from a quantitative examination of the cation exchange capacity of the coleoptile cell wall, which was shown to be due ...
... growth, whereas reducing its concentration promoted cell and tissue elongation (Bennet-Clark, 1956 ; Tagawa and Bonner, 1957 ). Strong support for the Ca2+/pectate interaction came from a quantitative examination of the cation exchange capacity of the coleoptile cell wall, which was shown to be due ...
Utilization and Transport of Mannitol in Olea
... a 250 and 500 mM NaCl pulse, whereas extensive loss of cell viability was observed in sucrose-grown cells. OeMaT1 transcripts increased throughout maturation of olive fruits, suggesting that an OeMaT is involved in the accumulation of mannitol during ripening of olive. Thus, mannitol transport and c ...
... a 250 and 500 mM NaCl pulse, whereas extensive loss of cell viability was observed in sucrose-grown cells. OeMaT1 transcripts increased throughout maturation of olive fruits, suggesting that an OeMaT is involved in the accumulation of mannitol during ripening of olive. Thus, mannitol transport and c ...
Glycosyltransferases and Transpeptidases/Penicillin-Binding
... “miraculous” penicillin antibiotic that inactivates these enzymes. Since the discovery of penicillin “miraculous” penicillin antibiotic that inactivates these enzymes. Since the discovery of penicillin and and its wide utilization in medicine in the 1940s, several new classes and generations of rela ...
... “miraculous” penicillin antibiotic that inactivates these enzymes. Since the discovery of penicillin “miraculous” penicillin antibiotic that inactivates these enzymes. Since the discovery of penicillin and and its wide utilization in medicine in the 1940s, several new classes and generations of rela ...
Live Imaging of Drosophila Brain Neuroblasts Reveals a Role for
... Lis1 is required for nuclear migration in fungi, cell cycle progression in mammals, and the formation of a folded cerebral cortex in humans. Lis1 binds dynactin and the dynein motor complex, but the role of Lis1 in many dynein/dynactindependent processes is not clearly understood. Here we generate a ...
... Lis1 is required for nuclear migration in fungi, cell cycle progression in mammals, and the formation of a folded cerebral cortex in humans. Lis1 binds dynactin and the dynein motor complex, but the role of Lis1 in many dynein/dynactindependent processes is not clearly understood. Here we generate a ...