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Catalog 2 Version: January 2013 University of Illinois at Chicago
Catalog 2 Version: January 2013 University of Illinois at Chicago

... Novel salicylate-based analogs serve as pro-drugs for free aspirin release and quinone-methide formation. The quinone moiety can be biologically active because it can chemically modify proteins and induce reactive oxygen species (ROS) stress in breast cancer cells. Additionally, these compounds are ...
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... Shows distribution of body fluids in adults. Fluids move freely in and out of the cell in both directions (osmosis and diffusion) MACROMOLECULES: large molecule made up of smaller molecules that are linked together, known as nutrients - These nutrients are raw molecules that bodies need to provide e ...
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... form pores or channels that allow small watersoluble molecules normally unable to pass the membrane to cross. • Channel proteins have characteristic size and amino acid charges lining inside the pore. • These differences make each type of channel specific to passage of particular ions (i.e. Na+, K+, ...
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... • A gas always diffuses from a region of higher partial pressure to a region of lower partial pressure • Air is more conductive to gas exchange than water because air has a higher O2 content, lower density, and lower viscosity ...
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... in tissue and live for several months or longer ...
GPS-GSE Science Crosswalk 7th Grade
GPS-GSE Science Crosswalk 7th Grade

... investigate the diversity of living organisms and how they can be compared scientifically. a. Develop and defend a model that categorizes organisms based on common characteristics. b. Evaluate historical models of how organisms were classified based on physical characteristics and how that led to th ...
2014 Advanced Placement Biology Summer Work
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... encouraged) to contact me by email during the summer should you have any questions or concerns. ([email protected]) Please do NOT procrastinate on these projects; you will not be happy with the overall end result. On the 3rd day of class, you will have a 120-point test covering your summer work. ...
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... To examine the cellular effects of BUdR the drug was given r.p. at a dose of 500 mg/kg dissolved in 0-6 ml normal saline. The fetuses were recovered at hourly intervals up to 18 h after injection and subsequently at 12 or 24 h intervals until day 19 of pregnancy. Postnatal animals were recovered at ...
Single gene encourages growth of intestinal stem cells, supporting
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... progression. On the flip side, turning up expression of these genes or their pathways could help researchers grow new intestinal tissue to replace tissue destroyed by diseases such as inflammatory bowel disease or radiation treatment for cancer. "What we discovered is something referred to as the Go ...
Pengantar Biokimia Pertemuan 1
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... 3. Medical research, which increasingly seeks to understand disease states in molecular terms. 4. Nutrition, which has illuminated metabolism by describing the dietary requirements for maintenance of health. ...
Urinary System Lab 2014 Answers
Urinary System Lab 2014 Answers

... c) Carefully bisect the kidney longitudinally so the cut passes through the centre of the hilum. Name and locate i) renal cortex, ii) renal medulla, iii) renal pelvis Please refer to p. 467 of your textbook for an effective diagram of how to cut your kidney. d) The medullary portion of the kidney is ...
Ch.4 Powerpoint - St. Clair Schools
Ch.4 Powerpoint - St. Clair Schools

... • Contractions: reduce distance between 2 bones, the circumference of a lumen (capillaries), or the volume of a chamber (heart). • Classification based on the type of innervation (dist of nerves – voluntary or involuntary) and the visibility by light microscope of microfilaments (striated or unstria ...
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... organization with no nucleus or other membrane-bound organelles. • Example: Bacteria • Diseases caused by bacteria: Cholera, ...
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... • Either attack cells or secrete toxins c. Nitrogen-fixing bacteria (Rhizobium) • Found in nodules of soybeans, ...
IUPUI Transgenic and Knockout Center
IUPUI Transgenic and Knockout Center

... embryos are then surgically implanted into foster mothers and allowed to develop to term. Approximately 20% of the resulting mice will have stably incorporated the transgene. Once integrated, the transgene can typically be transmitted to subsequent generations in a Mendelian fashion. By incorporatin ...
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Circulatory System - Life Education Trust Logo
Circulatory System - Life Education Trust Logo

... and nutrients to our cells. It also picks up waste products such as carbon dioxide so they can be removed from the body. The heart is the pump that pushes blood through the circulatory system to every part of our body - all day, every day for our whole life. The Lymphatic System is an associated sys ...
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... • Weak antigens such as these are called allergens. • The response itself can cause some degree of tissue damage. ...
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22. Myxobacterial Differentiation

... b. The length of the amoeboid cell allows orientation in a gradient, so they can (and do) respond to spatial gradients. 2. a. Myxobacteria feed in packs and move slowly.  they can use cell surface signals rather than small diffusible molecules. The use of cell surface macromolecules as attractants ...
Ectopic expression of natural resistance
Ectopic expression of natural resistance

... Nrampl in COS-I cells was consistently associated with a reduction in the measured iron content when compared to COS-1 cells transfected with vector alone. A mean reduction in cell associated iron of nearly 40% was observed over three experiments. This result is supported by the work of Zwilling and ...
Dual function of histone H3K76 methylation in cell cycle regulation
Dual function of histone H3K76 methylation in cell cycle regulation

... includes different parasite forms: the procyclic form, which lives in the intestinal tract of an insect vector (the tsetse fly) and the bloodstream form, which is adapted to the vascular system of a mammalian host. Many cellular processes, including cell cycle control, changes in protein expression ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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