• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Arabidopsis Kinetochore Fiber-Associated MAP65-4
Arabidopsis Kinetochore Fiber-Associated MAP65-4

... attach the kinetochore MTs to a spindle pole body or a centrosome. Instead, pole focusing of the kinotochore fibers has been proposed to rely on minus end–directed motors that may form cross-links between individual MTs (Smirnova et al., 1998; Chen, 2002; Ambrose et al., 2005). Selective cross-linki ...
Core homework booklet higher
Core homework booklet higher

... 1.4 Describe the main characteristics of the phylum chordata as animals with a supporting rod running the length of the body, an example of this being the backbone in vertebrates. 1.5 Explain how scientists place vertebrates into groups based on a oxygen absorption methods – lungs, gills and skin b ...
Branching morphogenesis of the Drosophila tracheal system. Annual Review of Cell Developmental Biology 19, 623-647. pdf
Branching morphogenesis of the Drosophila tracheal system. Annual Review of Cell Developmental Biology 19, 623-647. pdf

... organize into tubes. Each of the six primary branches undergoes a similar budding process, with some differences. For example, a different but characteristic number of cells (from 4 to 20) is recruited into each branch. Also, most but not all primary branches subsequently undergo a 2-h period of cel ...
The O-antigen mediates differential survival of
The O-antigen mediates differential survival of

... environment. Predators known to consume antigenically distinct prey with different efficiencies are also differentially distributed. Here we show that antigenically distinct, but otherwise isogenic and physiologically indistinct, strains of Salmonella enterica show differential survival in natural s ...
Identification of Plasmodium falciparum var1CSA
Identification of Plasmodium falciparum var1CSA

... parasites expressing this var gene have been shown not to bind human IgM [17]. All domains of var1CSA were expressed at the surface of the COS-7 cells. Only the DBL7␧ domain showed IgM binding by IFA with a mouse mAb to human IgM, with 10–15% of the COS-7 cells showing bright surface fluorescence (T ...
Chediak-Higashi–Like Granules in Acute
Chediak-Higashi–Like Granules in Acute

... features of gigantic azure granules seen in two cases of acute promyelocytic leukemia.1 One case of acute promyelocytic leukemia (APL) with Chediak-Higashi (CH)-like granules diagnosed at the Division of Hematology, Department of Internal Medicine (Medical Faculty Hospital, Skopje, Macedonia) in 197 ...
Pathophysiology of ischemia-reperfusion injury: experimental data
Pathophysiology of ischemia-reperfusion injury: experimental data

... The early generation of complement-derived chemotactic factors does not depend upon reperfusion, but reperfusion of the infarcted myocardium accelerates other cellular and cytokine responses. This acceleration enables the early entry of neutrophils into the viable border zone surrounding the myocard ...
p53 transcriptional activity is essential for p53dependent apoptosis
p53 transcriptional activity is essential for p53dependent apoptosis

Self-assembled pH-responsive hyaluronic acid–g-poly(l
Self-assembled pH-responsive hyaluronic acid–g-poly(l

... [24]. Although the HA-ss-DOCA carrier has some advantages for drug delivery, it requires a disulfide bond in linkages and the glutathione (GSH) responsive micelle degradation depends on a high level of GSH. However, the pH-responsive system is independent of the cellular chemical substances and does ...
Aprotinin Preserves Cellular Junctions and Reduces
Aprotinin Preserves Cellular Junctions and Reduces

... minutes after CPB. Intravenous fluids were administered post-CPB to maintain a mean arterial pressure (MAP) of 60 mm Hg. The treatment group received aprotinin systemically (Bayer Pharmaceuticals Corporation) as follows: a 40 000 KIU/kg IV loading dose, 40 000 KIU/kg CPB circuit prime, and 10 000 KI ...
Essential oils in food preservation
Essential oils in food preservation

... Essential oils are aromatic and volatile liquids extracted from plants.The chemicals in essential oils are secondary metabolites, which play an important role in plant defense as they often possess antimicrobial properties. The interest in essential oils and their application in food preservation ha ...
A Dominant Negative Mutant of Cyclin-Dependent
A Dominant Negative Mutant of Cyclin-Dependent

... 1985; Dilkes et al., 2002). Coincidentally, these cells become enlarged and begin to accumulate starch and storage proteins (Lopes and Larkins, 1993). Accumulation of storage metabolites continues until 40 to 45 DAP, but beginning around 20 DAP, the large central starchy endosperm cells begin to und ...
Mobile Factories: Golgi dynamics in plant cells
Mobile Factories: Golgi dynamics in plant cells

... eukaryotic cells. In addition to the trafficking and sorting function imparted on this organelle by its central location, it also functions as an important biosynthetic compartment that modifies proteins and synthesizes polysaccharides and lipids. The Golgi apparatus of most cell types is well known ...
Human Respiration
Human Respiration

...  The bronchi contain cartilage rings as well  The bronchi subdivide many times forming smaller tubules known as bronchioles ...
The Dual Function of Sugar Carriers: Transport and Sugar
The Dual Function of Sugar Carriers: Transport and Sugar

... the yeast hexose transporters (HXTs), which function as uniporters, the C. kessleri hexose transporter is a symporter (Sauer et al., 1990a; Aoshima et al., 1993). Despite this difference in the transport mechanism, yeast and C. kessleri transporter genes are homologous, encoding proteins composed of ...
Purine nucleosides: endogenous neuroprotectants in hypoxic brain
Purine nucleosides: endogenous neuroprotectants in hypoxic brain

... sine), adenosine kinase (phosphorylates adenosine to 5¢AMP) and nucleoside transporters, are responsible for an extremely short half-life of adenosine in circulation (Fredholm et al. 2001a, 2011; Eltzschig 2009) and therefore some of its effects, are apparently due to its metabolites as was reported ...
Responses to Cell Loss Become Restricted as the Supporting Cells
Responses to Cell Loss Become Restricted as the Supporting Cells

... Figure 2. LatA treatments did not produce detectable changes in the size of the reinforced F-actin bands in adult mouse utricles. A, Confocal images of sensory epithelia (SE) that were cultured with 5 ␮M LatA or vehicle control for 1, 12, or 24 h and then fixed and labeled with fluorescent phalloidi ...
Formation of Persisting Cell Wall Deficient Forms of Mycobacterium
Formation of Persisting Cell Wall Deficient Forms of Mycobacterium

... to the observed L-form conversion phenomenon, BCG L-form cultures were isolated from animals on 45 day after challenge. The demonstration that BCG bacilli can convert to cell wall deficient forms(Lforms) inside resting or pre- activated macrophages in vivo suggests that this phenomenon could signifi ...
Science - the Southwick-Tolland-Granville Regional School District
Science - the Southwick-Tolland-Granville Regional School District

... information from their mother and half from their father, and that sexually produced offspring resemble, but are not identical to, either of their parents. ...
Extended PDF
Extended PDF

... 2006a; Branda et al., 2004; Romero et al., 2010). B. subtilis biofilms have a limited life span, maturing after 3 days of incubation in biofilm-inducing medium at 22 C but disassembling and releasing individual planktonic cells by 8 days (Kolodkin-Gal et al., 2010; Romero et al., 2011). How do cell ...
TGLN Manual - Trillium Gift of Life Network
TGLN Manual - Trillium Gift of Life Network

... has given renewed hope to another human being. Every effort has been made to ensure that all information and references contained in the manual are as up-to-date as possible. However, the constantly evolving world of legislation, guidelines and research can have a direct impact on the contents conta ...
the pregnane x receptor binds to response elements in a genomic
the pregnane x receptor binds to response elements in a genomic

... from Fisher Scientific Co. (Pittsburgh, PA). Full-length cDNA encoding human PXR was isolated from a cDNA library by a cDNA-trapping procedure with a biotinylated oligonucleotide ACAGTGGCTGTGAGCTTCCAG as described previously (Hu and Yan, 1999; Zhang et al., 1999). The coding sequence was amplified b ...
Molecular Microbiology
Molecular Microbiology

... the supernatant of this mutant was tested in the dropcollapsing assay. Results show that the supernatant of PCL1436 did not spread on a hydrophobic support, in contrast to supernatant derived from the wild-type strain (Fig. 1B). The culture supernatant from mutant derivative PCL1436 showed a surface ...
S6 Table. GO categories found to be significantly modified in AhERF
S6 Table. GO categories found to be significantly modified in AhERF

... post-embryonic organ morphogenesis, cellular component morphogenesis, cellular developmental process, cell morphogenesis, cell differentiation, cell development, cell morphogenesis involved in differentiation growth, developmental growth involved in morphogenesis, unidimensional cell growth, develop ...
Laser Microdissection and Spatiotemporal Pinoresinol
Laser Microdissection and Spatiotemporal Pinoresinol

... activities in various parts of the flaxseed to obtain temporal information about LuPLR1 gene expression. In this article, we describe the cell layer-specific detection of secondary metabolites by using chemical and molecular methods in parallel to elucidate both the spatial distribution of SDG as we ...
< 1 ... 61 62 63 64 65 66 67 68 69 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report