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kdfkdfjsdk
kdfkdfjsdk

... antibodies to red cell antigens, may have to distinguish autofrom allo-antibodies, if present.  Prepare and test eluate from DAT positive RBCs to define whether coating protein has red cell antibody specificity. ...
Cell cycle: Checkpoint proteins and kinetochores
Cell cycle: Checkpoint proteins and kinetochores

... single chromosome is not properly attached to the spindle (Figure 1b) [11]. This arrest is caused by an inhibitory signal emanating from kinetochores that are not attached to the spindle apparatus [12]. Genetic studies in yeast have identified some of the molecules involved in the spindle assembly c ...
ASXL1 interacts with the cohesin complex to maintain chromatid
ASXL1 interacts with the cohesin complex to maintain chromatid

... sides its major function in sister chromatid cohesion, the cohesin complex participates in many other cellular processes, such as transcriptional regulation through long-range cis interactions (20–26). Recently, clinical studies have discovered recurrent mutations or deletions in the cohesin genes i ...
Chapter 14 Circulation and Respiration The Cardiovascular System
Chapter 14 Circulation and Respiration The Cardiovascular System

... They consist of 3 separate layers: • Layer of Epithelial Cells (smooth inner layer that allows blood to flow freely) • Smooth Muscle (muscular middle layer that controls the amount of blood that flows to an area) • Connective Tissue (strong outer layer that protects the artery from bursting from the ...
A Division-Dependent Compartmental Model for Computing Cell
A Division-Dependent Compartmental Model for Computing Cell

... Traditional deconvolution techniques (such as fitting peaks with normal or lognormal curves) impose particular forms on the experimental data which may bias the computed number of cells in each generation. While all these efforts to date correspond to several iterations in an iterative modeling proc ...
Mader/Biology, 11/e – Chapter Outline
Mader/Biology, 11/e – Chapter Outline

... 3) Capillaries are so narrow that red blood cells must pass through them in single file. 4) Gas, nutrient, and waste exchange occurs across the thin capillary walls. d. The venules are vessels that take blood from capillaries and join to form a vein. e. Veins transport blood toward the heart. 1) The ...
Orientation to the Human Body
Orientation to the Human Body

... and nutrients to all body cells and delivers wastes and carbon dioxide to disposal organs ...
Genetic Analysis of the Yeast Cytoskeleton.
Genetic Analysis of the Yeast Cytoskeleton.

... proteins can be identified by cloning each gene (in yeast by complementing the defect in vivo) and then raising antibodies by using the gene to make fusion proteins or synthetic peptides. The alternate procedure(plan B) begins with proteins identified biochemically as part of the cytoskeleton. The g ...
Listeria Nontoxic radioactive is a highly effective therapy against metastatic pancreatic cancer
Listeria Nontoxic radioactive is a highly effective therapy against metastatic pancreatic cancer

... effective in eradicating primary tumors through combinations of surgery, radiation, and adjuvant therapy. The reason that cancer remains such a formidable health problem is its capacity to recur in the form of widespread metastases, often with a fatal consequence. In a previous study, we found that ...
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Respiration and Circulation Blood

... longer function. Clumps form because of clumping proteins in blood plasma, shown in the table above. The type of clumping proteins in your blood determines what blood type you could safely get in a transfusion. A, B, and O blood types have clumping proteins in their plasma. A person with type A bloo ...
Biology II—Honors (I) Curriculum Content Portfolio Evidence
Biology II—Honors (I) Curriculum Content Portfolio Evidence

... (models) of evolutionary history that can be tested C. Life continues to evolve within a changing environment. 1. Speciation and extinction have occurred throughout the Earth’s history 2. Speciation may occur when two populations become reproductively isolated from each other 3. Populations of organ ...
Overexpression of a truncated cyclin B gene arrests Dictyostelium
Overexpression of a truncated cyclin B gene arrests Dictyostelium

... cells (Maeda et al., 1989). A variety of low molecular mass factors have also been shown to influence the formation of both stalk and spore cells, and these molecules have been proposed as morphogens responsible for generating and maintaining the spatial pattern (for review, see Weeks and Gross, 199 ...
Chapter 24
Chapter 24

... air to the bronchopulmonary segments of the lung. vi. Lobules and Alveoli: a. Each bronchopulmonary segment has many small compartments called lobules. b. Each lobule is wrapped in elastic connective tissue and contains a lymphatic vessel, an arteriole, a venule, and a branch of a terminal bronchiol ...
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PDF

... 30 mm diameter (Falcon) for 1 day. Aggregates comprising approximately 100 cells were collected by a capillary and transferred to 96-well microtiter plates (Falcon) containing 0-1 ml of DME-FCS with various concentrations of RA. Each well contained about five aggregates. Under these conditions, aggr ...
Control of the Plant Cell Cycle by Developmental
Control of the Plant Cell Cycle by Developmental

... mediate physical interaction between the APC/C and its substrates, and, according to studies in other organisms, APC/ CCDC20 and APC/CCDH1 exert distinct activities during the cell cycle. Yeast and animal APC/CCDC20 is activated during early mitosis and targets mitotic CYCs and securin for degradati ...
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Cells_Review_Game_wi..

... This organelle is found in plant cells and turns water, carbon dioxide and light into ...
Blood components contribute to exchange, transport, and defense
Blood components contribute to exchange, transport, and defense

... • Diffusion time is proportional to the square of the distance • Diffusion is only efficient over small distances • In small and/or thin animals, cells can exchange materials directly with the surrounding medium • In most animals, cells exchange materials with the environment via a fluid-filled circ ...
FUNGI
FUNGI

... Hyphae - Thin filaments of a fungus that form its body or mycelium Isogamous - Iso implies the same and gamous refers to gametes. In isogamous species the gametes are the same size and shape, thus individuals are not male or female but are referred to as being + or -. Karyogamy - The fusion of nucle ...
Fetal Pig Dissection HB
Fetal Pig Dissection HB

... 4. All of the stomachs of the pigs were empty. Why wouldn’t any of them be full? (hint: where does the fetal pig get its food from?) __________________________________________________________________ __________________________________________________________________ _________________________________ ...
Efficient Endosomal Localization of Major Histocompatibility
Efficient Endosomal Localization of Major Histocompatibility

... endosomes (Lamb and Cresswell, 1992; Arunachalam et al., 1993; Romagnoli et al., 1993; Simonsen et al., 1993). Iimediated endosomal localization appears to occur both by targeting (Odorizzi et al., 1994) and retention (Neefjes and Ploegh, 1992; Loss and Sant, 1993). Although the transmembrane domain ...
the Sec7 family of guanine-nucleotide- exchange factors
the Sec7 family of guanine-nucleotide- exchange factors

... ARF–membrane interaction is stabilized in the GTPbound form by a conformational change in the Nterminal helix that exposes several hydrophobic residues, including Leu8 and Phe9 (which are buried inside the ARF protein in its GDP-bound form), and allows their insertion into the membrane11. This inter ...
ch 42 presentation cardiovascular
ch 42 presentation cardiovascular

... • Diffusion time is proportional to the square of the distance • Diffusion is only efficient over small distances • In small and/or thin animals, cells can exchange materials directly with the surrounding medium • In most animals, cells exchange materials with the environment via a fluid-filled circ ...
Lab Dept: Microbiology/Virology Test Name: GRAM STAIN
Lab Dept: Microbiology/Virology Test Name: GRAM STAIN

... or nursing station will be notified and another specimen will be requested before the specimen is discarded. ...
Leading articles How to choose delivery devices for asthma
Leading articles How to choose delivery devices for asthma

... nebulisation. Two thirds of the dose released from the nebuliser may be released during expiration and passes into the surrounding air. With many nebulisers, less than 10% of the prescribed dose reaches the lung. The nebuliser does not rely on patient cooperation or coordination to work, although de ...
Full Article
Full Article

... failure (ARF), in emergency hospitals worldwide is highly independent of its different underlying causes. The use of certain antibiotics, like gentamicin, which determines the rapid loss of kidney ability to remove waste and stabilize the balance of fluids and electrolytes, finally causing AKI in ch ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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