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Basement membrane matrices in mouse embryogenesis
Basement membrane matrices in mouse embryogenesis

... in early development and teratocarcinoma differentiation. In the early embryo a compartmentalization of newly formed cell types takes place immediately by formation of basement membranes The stage-specific developmental appearance of extracellular matrix molecules such as type IV collagen, laminin. ...
Cell migration: mechanisms of rear detachment and the formation of
Cell migration: mechanisms of rear detachment and the formation of

... processes, including embryogenesis, tissue repair and regeneration as well as cancer and the inflammatory response. In general, cell migration can be usefully conceptualized as a cyclic process. The initial response of a cell to a migration-promoting agent is to polarize and extend protrusions in th ...
Genetic Control of Programmed Cell Death in the Nematode C
Genetic Control of Programmed Cell Death in the Nematode C

... Ammals of the indicated genotypes were observed using Nomarski differential interference contrast microscopy. The numbers of dead cells present in the head of first larval stage (Ll) animals, the ventral cord, and right anteriolateral hypodermis (where progeny of the QR blast cell are generated) of ...
Built to rebuild: in search of organizing principles in plant
Built to rebuild: in search of organizing principles in plant

... shown that callus is not a homogenous mass but retains root meristem identity [10,15]. Even callus generated in vitro from the pericycle of aerial organs, a layer that does not produce lateral roots in planta, passed through cellular states reminiscent of those found in the root meristem, as judg ...
d-glucose-sensitive neurosecretory cells of the crab cancer borealis
d-glucose-sensitive neurosecretory cells of the crab cancer borealis

... and was carried by K+. However, the glucose-regulated K+ conductance does not appear to be an ATP-sensitive K+ channel and thus may constitute either a new kind of sugaractivated channel or receptor, or a channel-coupled glucose transport system. Some of these results have been reported in abstract ...
S 7.1 All living organisms are com- posed of cells, from just one to
S 7.1 All living organisms are com- posed of cells, from just one to

... of similar cells that work together to perform a specific function. For example, your brain is mostly made up of nervous tissue, which consists of nerve cells. An organ, such as your brain, is made up of different kinds of tissues that work together. In addition to nervous tissue, your brain contain ...
The Intracellular Growth of Fowl -Plague Virus
The Intracellular Growth of Fowl -Plague Virus

... them; and furthermore, long filaments appear in infected epithelial cells growing in sheets in which there were no fibroblasts; epithelium does not produce collagen. Mitochondria are readily distinguished by their much greater size and less distinct outline. The uniform thickness, the segmentation, ...
Epithelial repair is a two-stage process driven first by dying cells and
Epithelial repair is a two-stage process driven first by dying cells and

... releasing the apical parts into the lumen (Bird et al., 2010). In cultured epithelial monolayers, dying cells can be extruded from the epithelium either apically (Rosenblatt et al., 2001) or basally (Slattum et al., 2009), and the latter has been suggested to be a possible cause of cancer progressio ...
Nanotechnology is a highly promising and exciting cross
Nanotechnology is a highly promising and exciting cross

... may be other routes of entry such as direct passage across gill and other external surface epithelia (Moore, 2006). Recent studies with fish have indicated that C60-fullerene may be internalised by these routes, although this was a very limited investigation (Oberdörster, 2004) and employed a solven ...
Gene Section PKD1 (protein kinase D1) Atlas of Genetics and Cytogenetics
Gene Section PKD1 (protein kinase D1) Atlas of Genetics and Cytogenetics

... homology (PH) and kinase domain (KD). Several domain specific protein interactions and functions have been described (see figure below). ...
Hemolytic Anemias
Hemolytic Anemias

... Laboratory findings I- Increased RBC destruction • Decreased RBC life span ...
Sticking the Landing: Probing the Roles of LORELEI
Sticking the Landing: Probing the Roles of LORELEI

... phenotypes and exhibited altered localization, indicating that the modification in M8CM is critical for LRE’s role in pollen tube reception. The authors then supplied LRE-cYFP directly to the synergid cell surface of lre by ectopically expressing it in pollen tubes where endogenous LRE was not expre ...
933 - Scope, Sequence, and Coordination
933 - Scope, Sequence, and Coordination

... quickly so hold the pipette on the filter paper for a very short time. A small circle of solution, approximately the diameter of a pencil, is all that is required. Allow about 30 seconds for the spot to dry. Add another drop of pigment solution to the same spot. Repeat this procedure until 20 applic ...
What is Nanotechnology?
What is Nanotechnology?

... formed by a monolayer of phospholipids. Whereas liposomes are typical carriers for water substances, nanoparticles are the ideal delivery system to transport and ...
MITOCHONDRIAL PLASTICITY IN SKELETAL MUSCLE CELLS
MITOCHONDRIAL PLASTICITY IN SKELETAL MUSCLE CELLS

... Neuropathy, ataxia, retinitis pigmentosa, and ptosis (NARP) Myoclonic Epilepsy with Ragged Red Fibers (MERRF) progressive epilepsy, "Ragged Red Fibers" – clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as "Ragged ...
The Par3/Par6/aPKC Complex and Epithelial Cell Polarity
The Par3/Par6/aPKC Complex and Epithelial Cell Polarity

... In one-cell embryos such as C.elegans embryos where the anterior-posterior polarity is believed to be generated stochastically by actomyosin flow at the sperm entry site [2]. In multicellular system, “touching” by neighbors is a resemblance of fertilization process and is crucial for the later diffe ...
Muramatsu M
Muramatsu M

... accounting for an effective humoral response to harmful microbes. The molecular mechanisms for these genetic events remain to be elucidated despite intensive study. To dissect the molecular mechanism of class switching, we have isolated a murine B lymphoma clone CH12F3-2 in which CSR from IgM to IgA ...
In vitro control of neuronal polarity by
In vitro control of neuronal polarity by

... Fig. 2 illustrates the morphological influence of the addition of 4 fig ml" 1 EHS proteoglycans, a concentration that did not affect cell viability (Table 1). In control conditions (Fig. 2A), cell bodies are spread with short neurites and numerous cytoplasmic veils. The presence of the proteoglycans ...
Passive Transport
Passive Transport

... • The direction of water movement in a cell depends on the concentration of the cell’s outside environment. • If the solution is hypertonic, or has a higher solute concentration than the cytoplasm does, water moves out of the cell. The cell loses water and shrinks. • If the solution is hypotonic, or ...
Polycystin-2 functions as an intracellular calcium release channel.
Polycystin-2 functions as an intracellular calcium release channel.

... most notably the ER9,12. In addition, the cytoplasmic tail of polycystin-2 contains signals that are necessary for ER retention9,12. Cell-surface biotinylation assays also suggest that native polycystin2 is not transported to the cell surface in epithelial cells12. Immunohistochemical studies have d ...
The a4 Nicotinic Receptor Promotes CD4 T
The a4 Nicotinic Receptor Promotes CD4 T

... The a41 cells were also analyzed using LC-ESI MS (Supplemental Fig. 1). A cluster of differentiation (CD) system was used for immunophenotyping the a41 cell fraction. A list of CD markers within the a41 fraction is presented in Supplemental Table 1. A significant number of T cell, B cell, and macrop ...
β Glucocorticoids on IL-1 Counteract the Inhibitory Effect of Migration
β Glucocorticoids on IL-1 Counteract the Inhibitory Effect of Migration

... phospholipase A2 activity; down-regulate the synthesis and secretion of IL-1, IL-6, and TNF-␣ from activated monocytes and macrophages; and inhibit cytokine-induced transcription factors, such as NF-␬B and AP1 (32, 33). The crucial role of glucocorticoids has been demonstrated in a number of studies ...
The study of cell cycle control is entering a new and exciting phase
The study of cell cycle control is entering a new and exciting phase

... literally, cell cycle events and processes will include all those that are required for cellular growth as well as those for direct reproduction of the cell. Such a literal interpretation is rather unfocused since it will include processes such as protein and RNA synthesis, which are only indirectly ...
DNA asymmetry in stem cells – immortal or mortal?
DNA asymmetry in stem cells – immortal or mortal?

Life Science Final Review - Saint Mary Catholic School
Life Science Final Review - Saint Mary Catholic School

... Mendel's First Law of Genetics (Law of Segregation): A gene that can exist in more than 1 form (e.g. a gene for round or w_______________________ peas) is called an a________________________. When gametes are produced (by meiosis) in the parent, allele pairs separate leaving each g_______________ wi ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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