Negative regulation of the interferon response by
... in mammalians, a much larger fraction of the genome is transcribed into long non-coding transcripts (1,2). These transcripts, the long non-coding RNAs (lncRNAs), constitute a novel layer of regulatory factors with important roles in almost every aspect of cellular function (3–9). The expression of m ...
... in mammalians, a much larger fraction of the genome is transcribed into long non-coding transcripts (1,2). These transcripts, the long non-coding RNAs (lncRNAs), constitute a novel layer of regulatory factors with important roles in almost every aspect of cellular function (3–9). The expression of m ...
How to present a scientific paper
... • Lactate dehydrogenase A (LDH-A) is a key glycolytic enzyme, and its expression is increased in mouse mammary epithelial cells that overexpress a form of ErbB2 • Heat shock factor 1 (HSF1) is a transcription factor that regulates glucose metabolism which is itself regulated by Ras (a target of ErbB ...
... • Lactate dehydrogenase A (LDH-A) is a key glycolytic enzyme, and its expression is increased in mouse mammary epithelial cells that overexpress a form of ErbB2 • Heat shock factor 1 (HSF1) is a transcription factor that regulates glucose metabolism which is itself regulated by Ras (a target of ErbB ...
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... cholangiocytes but not on hepatocytes (de Boer et al., 1999; Momburg et al., 1987). Consistent with previous studies (Yovchev et al., 2007; Yovchev et al., 2008), real-time PCR showed that Epcam was expressed in normal rat liver and its expression was upregulated by 2-AAF/PH (Fig. 1B). As for mouse ...
... cholangiocytes but not on hepatocytes (de Boer et al., 1999; Momburg et al., 1987). Consistent with previous studies (Yovchev et al., 2007; Yovchev et al., 2008), real-time PCR showed that Epcam was expressed in normal rat liver and its expression was upregulated by 2-AAF/PH (Fig. 1B). As for mouse ...
Dynamic Clamp
... A real cell can be connected to one or more in silico artificial cells. Synchronization between reciprocally connected cells in a network can be studied. Could be used for model validation. Model can be tested in vitro with a real cell. ...
... A real cell can be connected to one or more in silico artificial cells. Synchronization between reciprocally connected cells in a network can be studied. Could be used for model validation. Model can be tested in vitro with a real cell. ...
PGC specification from epiblast
... cells are destined for each somatic cell lineage after passing through the primitive streak during gastrulation (Hogan et al., 1994). The presumptive PGC precursors located within the proximal epiblast may also pass through the posterior end of the primitive streak and reside in the extra-embryonic ...
... cells are destined for each somatic cell lineage after passing through the primitive streak during gastrulation (Hogan et al., 1994). The presumptive PGC precursors located within the proximal epiblast may also pass through the posterior end of the primitive streak and reside in the extra-embryonic ...
Candida albicans Iff11, a Secreted Protein Required for Cell Wall
... and then concentrated, and the buffer was exchanged to phosphate-buffered saline (PBS) by ultrafiltration (Amicon Ultra-10-kDa Cutoff; Millipore, Watford, United Kingdom). Samples were then further concentrated by ethanol precipitation and reconstituted in PBS. Whole cells were extracted with -merc ...
... and then concentrated, and the buffer was exchanged to phosphate-buffered saline (PBS) by ultrafiltration (Amicon Ultra-10-kDa Cutoff; Millipore, Watford, United Kingdom). Samples were then further concentrated by ethanol precipitation and reconstituted in PBS. Whole cells were extracted with -merc ...
Pluripotent Stem Cell Handbook
... Pluripotent stem cells (PSCs) is a term that encompasses both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Human ESCs (hESCs) are isolated from the inner cell mass of the blastocyst stage of a developing embryo and were first derived in 1998 by Dr. James Thomson at the Uni ...
... Pluripotent stem cells (PSCs) is a term that encompasses both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Human ESCs (hESCs) are isolated from the inner cell mass of the blastocyst stage of a developing embryo and were first derived in 1998 by Dr. James Thomson at the Uni ...
liver
... homeostasis and protects the rest of the body from dangerous spikes and drops in the blood glucose level. (See more about glucose in the body.) Fatty acids in the blood passing through the liver are absorbed by hepatocytes and metabolized to produce energy in the form of ATP. Glycerol, another lipid ...
... homeostasis and protects the rest of the body from dangerous spikes and drops in the blood glucose level. (See more about glucose in the body.) Fatty acids in the blood passing through the liver are absorbed by hepatocytes and metabolized to produce energy in the form of ATP. Glycerol, another lipid ...
Gene Section ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1)
... gene product shows about 40% homology with thrombospondin-1 and thrombospondin-2 (Kuno et al., 1997b). The TSP type I motifs present in the C-terminal half of ADAMTS1 are functional for binding to heparin. Moreover, analyses of deletion mutants have revealed that the carboxyl-terminal spacing region ...
... gene product shows about 40% homology with thrombospondin-1 and thrombospondin-2 (Kuno et al., 1997b). The TSP type I motifs present in the C-terminal half of ADAMTS1 are functional for binding to heparin. Moreover, analyses of deletion mutants have revealed that the carboxyl-terminal spacing region ...
Saquinavir, an HIV Protease Inhibitor, Is Transported by P
... specificity of saquinavir for viral proteases results in low toxicity to mammalian cells. Despite the small degree of resistance conferred by P-gp, these results suggest that this drug may be a substrate for P-gp-mediated transport. Additional low-toxicity or noncytotoxic drugs have previously been ...
... specificity of saquinavir for viral proteases results in low toxicity to mammalian cells. Despite the small degree of resistance conferred by P-gp, these results suggest that this drug may be a substrate for P-gp-mediated transport. Additional low-toxicity or noncytotoxic drugs have previously been ...
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... show that Geminin overexpression represses many genes associated with cell commitment but increases the expression of genes that promote pluripotent and immature neuroectodermal cell fates. Geminin, they report, represses Activin-, FGF- and BMP-mediated cell commitment. Consistent with this finding, ...
... show that Geminin overexpression represses many genes associated with cell commitment but increases the expression of genes that promote pluripotent and immature neuroectodermal cell fates. Geminin, they report, represses Activin-, FGF- and BMP-mediated cell commitment. Consistent with this finding, ...
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... show that Geminin overexpression represses many genes associated with cell commitment but increases the expression of genes that promote pluripotent and immature neuroectodermal cell fates. Geminin, they report, represses Activin-, FGF- and BMP-mediated cell commitment. Consistent with this finding, ...
... show that Geminin overexpression represses many genes associated with cell commitment but increases the expression of genes that promote pluripotent and immature neuroectodermal cell fates. Geminin, they report, represses Activin-, FGF- and BMP-mediated cell commitment. Consistent with this finding, ...
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... show that Geminin overexpression represses many genes associated with cell commitment but increases the expression of genes that promote pluripotent and immature neuroectodermal cell fates. Geminin, they report, represses Activin-, FGF- and BMP-mediated cell commitment. Consistent with this finding, ...
... show that Geminin overexpression represses many genes associated with cell commitment but increases the expression of genes that promote pluripotent and immature neuroectodermal cell fates. Geminin, they report, represses Activin-, FGF- and BMP-mediated cell commitment. Consistent with this finding, ...
Lecture Herbicide x Plant Interactions Absorption and Translocation
... For this to occur the plant expends energy in the form of ATP, adenosine triphosphate, derived from other energy producing pathways within the plant process involved: energy released from conversion of ATP to ADP by ATPase used to pump hydrogen (H+) ions to the outside of the cell, which affects pH ...
... For this to occur the plant expends energy in the form of ATP, adenosine triphosphate, derived from other energy producing pathways within the plant process involved: energy released from conversion of ATP to ADP by ATPase used to pump hydrogen (H+) ions to the outside of the cell, which affects pH ...
Chapter 3—Cells
... Answers may vary. Sample answer: In a single-celled organism, only one type of cell has to be adapted to the environment. Once that cell has so adapted, it can keep surviving as long as it continues to replicate. In a multicellular organism, there are likely to be many different kinds of cells. To s ...
... Answers may vary. Sample answer: In a single-celled organism, only one type of cell has to be adapted to the environment. Once that cell has so adapted, it can keep surviving as long as it continues to replicate. In a multicellular organism, there are likely to be many different kinds of cells. To s ...
The fully assembled flow cell apparatus you have
... bottle, slow the pump to about 10% value. Turn the stopcocks, one by one, to the open position and allow culture fluid to fill about 1/2 the cylinder; then turn the stopcock off. The captured air in the tops of the cylinder exerts a small positive pressure on the flowing medium. ...
... bottle, slow the pump to about 10% value. Turn the stopcocks, one by one, to the open position and allow culture fluid to fill about 1/2 the cylinder; then turn the stopcock off. The captured air in the tops of the cylinder exerts a small positive pressure on the flowing medium. ...
Centromere dynamics
... basis for epigenetic specification of centromere. A study from the pathogenic yeast reveals that pre-existing centromeres remain functional, but if they are isolated as naked DNA and reintroduced back into the cell, functional centromeres do not form [15]. These and other studies might force us to ...
... basis for epigenetic specification of centromere. A study from the pathogenic yeast reveals that pre-existing centromeres remain functional, but if they are isolated as naked DNA and reintroduced back into the cell, functional centromeres do not form [15]. These and other studies might force us to ...
The Basic Unit of Life
... of tea? When you put sugar in tea, you stir the liquid until the sugar dissolves in the liquid. As the sugar dissolves, it breaks apart into tiny pieces that you can no longer see. The water in the tea is the chemical that does the dissolving. Special properties of water allow it to break things apa ...
... of tea? When you put sugar in tea, you stir the liquid until the sugar dissolves in the liquid. As the sugar dissolves, it breaks apart into tiny pieces that you can no longer see. The water in the tea is the chemical that does the dissolving. Special properties of water allow it to break things apa ...
-Tubulin Plays an Essential Role in the Coordination of Mitotic Events
... arrested in late G2 by nimT23. They were then shifted rapidly from 43 to 20°C. This shift released the nimT23 block and imposed the mipAD159 block. Samples were collected immediately before the shift from 43 to 20°C and at intervals afterward and were prepared for immunofluorescence microscopy. As a ...
... arrested in late G2 by nimT23. They were then shifted rapidly from 43 to 20°C. This shift released the nimT23 block and imposed the mipAD159 block. Samples were collected immediately before the shift from 43 to 20°C and at intervals afterward and were prepared for immunofluorescence microscopy. As a ...
an eGOcentric view of tOrC1 signaling
... with and positively regulates mTORC1 in its GTP-bound state.3 Interestingly, TSC2, but not Rheb, appears to be dispensable for coupling amino acid signals to mTORC1, suggesting the existence of additional proteins that participate in amino acid regulation of mTORC1.4,5 In this context, two complemen ...
... with and positively regulates mTORC1 in its GTP-bound state.3 Interestingly, TSC2, but not Rheb, appears to be dispensable for coupling amino acid signals to mTORC1, suggesting the existence of additional proteins that participate in amino acid regulation of mTORC1.4,5 In this context, two complemen ...
The Hydra polyp: Nothing but an active stem cell community
... important question. All three stem cell types are adult stem cells, have an unlimited capacity for self-renewal, can differentiate into one or more cell types, and are an essential component of tissue homeostasis. Dividing stem cells of the interstitial lineage have a cell cycle time of 18–30 h, whi ...
... important question. All three stem cell types are adult stem cells, have an unlimited capacity for self-renewal, can differentiate into one or more cell types, and are an essential component of tissue homeostasis. Dividing stem cells of the interstitial lineage have a cell cycle time of 18–30 h, whi ...
Universal Quantifier Derived from AFM Analysis Links Cellular
... was measured again as ODs. The aggregation index is defined as ...
... was measured again as ODs. The aggregation index is defined as ...
Regulation by Polyamines of Ornithine
... whereas in untreated and putrescine- or spermidinetreated cultures, cells lost their motility before cell division (data not shown; for references, see Harris, 1989). These findings indicate that spermine affects the transition from the G1 to the S phase. In this context, it is important to know tha ...
... whereas in untreated and putrescine- or spermidinetreated cultures, cells lost their motility before cell division (data not shown; for references, see Harris, 1989). These findings indicate that spermine affects the transition from the G1 to the S phase. In this context, it is important to know tha ...
3:2
... –A network of thin, fibrous materials that act as a scaffold and support the organelles. –Microtubules – hollow filaments of protein. –Microfilaments – solid filaments of protein. ...
... –A network of thin, fibrous materials that act as a scaffold and support the organelles. –Microtubules – hollow filaments of protein. –Microfilaments – solid filaments of protein. ...