Nuclear Factor of Activated T Cells Transcription Factor NFATp
... showed 100 and 50% lethality with injection of 5 and 2 g of SEB, respectively (Table I). Strikingly, NFATp⫺Ⲑ⫺ mice showed very little or no signs of illness at all and completely recovered within 24 h when injected with the same concentrations of SEB that caused death in their NFATp⫹Ⲑ⫹ littermates. ...
... showed 100 and 50% lethality with injection of 5 and 2 g of SEB, respectively (Table I). Strikingly, NFATp⫺Ⲑ⫺ mice showed very little or no signs of illness at all and completely recovered within 24 h when injected with the same concentrations of SEB that caused death in their NFATp⫹Ⲑ⫹ littermates. ...
figure 2 - Open Biology
... requires a systems-level understanding of the signalling networks that respond to external cues and regulate the cytoskeleton. Classical biochemical and genetic approaches have identified thousands of individual components that contribute to cell shape, but it remains difficult to predict how cell s ...
... requires a systems-level understanding of the signalling networks that respond to external cues and regulate the cytoskeleton. Classical biochemical and genetic approaches have identified thousands of individual components that contribute to cell shape, but it remains difficult to predict how cell s ...
1 Breast Cancer Cell Line Development and Authentication
... Indoubtedly, the most important factor to change biomedical research and our understanding of disease at the cellular and molecular levels was the establishment of the first continuously growing human cell line, the HeLa cell (Gey et al., 1952). In 1952, Henrietta Lacks was a patient with adenocarci ...
... Indoubtedly, the most important factor to change biomedical research and our understanding of disease at the cellular and molecular levels was the establishment of the first continuously growing human cell line, the HeLa cell (Gey et al., 1952). In 1952, Henrietta Lacks was a patient with adenocarci ...
Targeting lactate metabolism for cancer therapeutics
... in the tumor cell milieu impairs the adaptive immune response, disabling immune surveillance (43–46). Thus, lactate also appears to promote tumorigenesis via non–tumor cell–mediated effects on the inflammatory and immune responses. Unexpectedly, a recent report of a mouse model of B cell lymphoma (λ ...
... in the tumor cell milieu impairs the adaptive immune response, disabling immune surveillance (43–46). Thus, lactate also appears to promote tumorigenesis via non–tumor cell–mediated effects on the inflammatory and immune responses. Unexpectedly, a recent report of a mouse model of B cell lymphoma (λ ...
Expression of the Activating Transcription Factor 3 Prevents c
... After nerve injury, an injured neuron initiates an organized cascade of molecular expression to promote survival and regeneration (Fawcett and Geller, 1998), and a failure or lack of the expression of some molecules leads to death of the neurons (Honma et al., 2002). This organized expression might ...
... After nerve injury, an injured neuron initiates an organized cascade of molecular expression to promote survival and regeneration (Fawcett and Geller, 1998), and a failure or lack of the expression of some molecules leads to death of the neurons (Honma et al., 2002). This organized expression might ...
Cell cycle`s deregulation and cardiovascular diseases
... • The interphase stage of the cell cycle includes three distinctive parts: o G1 phase- follows mitosis and is the period in which the cell is synthesizing its structural proteins and enzymes to perform its functions; o S phase- the DNA within the nucleus replicates o G2 phase- the cell prepares for ...
... • The interphase stage of the cell cycle includes three distinctive parts: o G1 phase- follows mitosis and is the period in which the cell is synthesizing its structural proteins and enzymes to perform its functions; o S phase- the DNA within the nucleus replicates o G2 phase- the cell prepares for ...
CTENIDIAL STRUCTURE AND THREE BACTERIAL SYMBIONT
... The structure of the ctenidia of the Indo-West Pacific chemosymbiotic lucinid bivalve Anodontia (Euanodontia) ovum was investigated by electron microscopy. Ctenidial filaments are similar in general morphology to those described from other Lucinidae, with a ciliated zone, a short intermediary zone and ...
... The structure of the ctenidia of the Indo-West Pacific chemosymbiotic lucinid bivalve Anodontia (Euanodontia) ovum was investigated by electron microscopy. Ctenidial filaments are similar in general morphology to those described from other Lucinidae, with a ciliated zone, a short intermediary zone and ...
PDF
... embryos to cytochalasins (Lee & Kalmus, 1976; Wiley, 1980; Morriss-Kay, 1981). Thus, the evidence suggests that in neuroepithelial cells a cytoskeletal network exists which acts as a force assisting in neurulation, presumably by contraction of the actomyosin complexes resulting in cell shape changes ...
... embryos to cytochalasins (Lee & Kalmus, 1976; Wiley, 1980; Morriss-Kay, 1981). Thus, the evidence suggests that in neuroepithelial cells a cytoskeletal network exists which acts as a force assisting in neurulation, presumably by contraction of the actomyosin complexes resulting in cell shape changes ...
Embryonic Stem Cells: from Blastocyst to in vitro Differentiation
... cultures are to become clinical-grade, since the use of animal feeders and/or ingredients for growth of hES cells limits the large-scale culture and medical applicability of hES cells. At present, feeder-free systems are not optimal for the derivation and growth of clinical-grade hES cell lines sinc ...
... cultures are to become clinical-grade, since the use of animal feeders and/or ingredients for growth of hES cells limits the large-scale culture and medical applicability of hES cells. At present, feeder-free systems are not optimal for the derivation and growth of clinical-grade hES cell lines sinc ...
Cells_and_Tissues__Ch_3__S2015_Part_1
... Vesicular Transport: transport in vesicles, moving substances into or out of the cell Exocytosis: vesicular transport out of the cell Endocytosis: vesicular transport into the cell Phagocytosis- uptake of bacteria or dead cells Receptor-mediated- specific binding to cell surface ...
... Vesicular Transport: transport in vesicles, moving substances into or out of the cell Exocytosis: vesicular transport out of the cell Endocytosis: vesicular transport into the cell Phagocytosis- uptake of bacteria or dead cells Receptor-mediated- specific binding to cell surface ...
Coombes JL, Han SJ, van Rooijen N, Raulet DH, Robey EA. 2012. Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus. Cell rep 2(1):124-135.
... with an immobile structure in the lymph node. Indeed, we observed that a substantial fraction of the slow-moving NK cells closely associated with second harmonic signals indicative of collagen fibers (Figure 3A; Movie S2). Antibody staining of lymph node tissue sections confirmed that these structur ...
... with an immobile structure in the lymph node. Indeed, we observed that a substantial fraction of the slow-moving NK cells closely associated with second harmonic signals indicative of collagen fibers (Figure 3A; Movie S2). Antibody staining of lymph node tissue sections confirmed that these structur ...
PDF
... FSCs in wild-type germaria were visible as Cas-positive, FasIIInegative cells at the 2a/2b boundary (Fig. 3A-A″). In Pak mutant germaria, additional Cas-positive, FasIII-negative cells were consistently seen at the interface of side-by-side cysts (Fig. 3BC″). FSCs secrete the integrin ligand LanA, w ...
... FSCs in wild-type germaria were visible as Cas-positive, FasIIInegative cells at the 2a/2b boundary (Fig. 3A-A″). In Pak mutant germaria, additional Cas-positive, FasIII-negative cells were consistently seen at the interface of side-by-side cysts (Fig. 3BC″). FSCs secrete the integrin ligand LanA, w ...
The following images will be similar to images you will
... • The presence of the structure at the tip of the pointer tells us that this is what type of cell? ...
... • The presence of the structure at the tip of the pointer tells us that this is what type of cell? ...
Cell signalling and gene regulation Plant signal transduction
... components. An important challenge now is to arrange all of these elements into testable signalling networks. Parks et al. (pp 436–440) describe how significant advances towards this goal are being made by time-resolved kinetic analysis of hypocotyl growth in wild-type plants and photomorphogenic mu ...
... components. An important challenge now is to arrange all of these elements into testable signalling networks. Parks et al. (pp 436–440) describe how significant advances towards this goal are being made by time-resolved kinetic analysis of hypocotyl growth in wild-type plants and photomorphogenic mu ...
localization of the succinic dehydrogenase system
... lesser density (Fig. 2). The plasma membrane (pm) is found subjacent to the cell wall delineating the protoplast (Fig. 2), but it is not well defined in our preparations which have not been stained ...
... lesser density (Fig. 2). The plasma membrane (pm) is found subjacent to the cell wall delineating the protoplast (Fig. 2), but it is not well defined in our preparations which have not been stained ...
Full Text - The International Journal of Developmental Biology
... of extraembryonic coelom separates these two somatopleural tissues from the splanchnopleural tissue, which becomes the later yolk sac. The amnion encloses the developing embryo by the end of E3 (Adamstone, 1948; Lillie, 1919; Romanoff, 1960; Wu et al., 2001). The remainder of the extraembryonic soma ...
... of extraembryonic coelom separates these two somatopleural tissues from the splanchnopleural tissue, which becomes the later yolk sac. The amnion encloses the developing embryo by the end of E3 (Adamstone, 1948; Lillie, 1919; Romanoff, 1960; Wu et al., 2001). The remainder of the extraembryonic soma ...
Chewing the fat on natural killer T cell development
... the strongest candidate ligand for NKT cell selection. It is important to add that even if LSD by itself impairs NKT cell development, this does not automatically exclude iGb3 as the candidate ligand (Fig. 1). However, more definitive studies are clearly necessary to test the hypothesis that iGb3 is ...
... the strongest candidate ligand for NKT cell selection. It is important to add that even if LSD by itself impairs NKT cell development, this does not automatically exclude iGb3 as the candidate ligand (Fig. 1). However, more definitive studies are clearly necessary to test the hypothesis that iGb3 is ...
coding space – head direction cells
... place cells encode more than simple space T-maze, trained (fruit loops) to alternate L & R turns subset of place cells showed interesting pattern e.g., activity (sector 3) anticipating right turns only suggests hippocampal network represents episodic memories, cells are small segments of a ...
... place cells encode more than simple space T-maze, trained (fruit loops) to alternate L & R turns subset of place cells showed interesting pattern e.g., activity (sector 3) anticipating right turns only suggests hippocampal network represents episodic memories, cells are small segments of a ...
Living together in biofilms: the microbial cell factory and its
... from the biofilm surface to the surrounding medium; it usually occurs in the early stages of biofilm development. Detachment involves external forces, such as abrasion, grazing, and erosion that are sufficient to disrupt the biofilm’s structure. In dispersion, regulatory systems enable physiological ...
... from the biofilm surface to the surrounding medium; it usually occurs in the early stages of biofilm development. Detachment involves external forces, such as abrasion, grazing, and erosion that are sufficient to disrupt the biofilm’s structure. In dispersion, regulatory systems enable physiological ...
Retroviruses and oncogenes II
... The ways in which these answers emerged are illuminating. In Denver, insight came from an inspired guess, based on the pleiotropism of src (22): protein phosphorylation ranks among the most versatile agents of change known to biochemists. In our laboratory, enzymological reasoning led the way (23): ...
... The ways in which these answers emerged are illuminating. In Denver, insight came from an inspired guess, based on the pleiotropism of src (22): protein phosphorylation ranks among the most versatile agents of change known to biochemists. In our laboratory, enzymological reasoning led the way (23): ...
Polarity and cell division orientation in the cleavage embryo: from
... components, localized in a polarized way along the animal– vegetal axis, still affect cell divisions and developmental potential of the blastomeres. The first cleavage plane in zygotes is almost exclusively meridional (M), which means it occurs along the animal–vegetal axis (Howlett and Bolton, 1985; ...
... components, localized in a polarized way along the animal– vegetal axis, still affect cell divisions and developmental potential of the blastomeres. The first cleavage plane in zygotes is almost exclusively meridional (M), which means it occurs along the animal–vegetal axis (Howlett and Bolton, 1985; ...