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The Anitschkow Prize in Atherosclerosis Research, 2013
The Anitschkow Prize in Atherosclerosis Research, 2013

... prestigious Anitschkow Prize 2013 (Diploma+10000 EUR) is Professor Peter Libby, Mallinckrodt Professor of Medicine at Harvard Medical School and Chief of the Cardiovascular Division at Brigham and Women's Hospital, Boston, Massachusetts. The Anitschkow Prize Recipient 2013 Here you can read more abo ...
The Tell-Tale Heart (Now, Optically Mapped)
The Tell-Tale Heart (Now, Optically Mapped)

... macroscopic level. Successful propagation from the central pacemaker cell (or group of cells) to atrial tissue is a tremendous physiological challenge. Normal propagation in cardiac tissue entails a delicate balance between depolarized cells (source) and the resting tissue ahead (sink) (12). Excited ...
Plant Cell Walls1 - Plant Physiology
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... advances have enhanced our understanding of the synthesis of these molecules (Ellis et al., 2010; Harholt et al., 2010; Scheller and Ulvskov, 2010), many important questions remain. At a biochemical level, we must identify and characterize the enzymes needed to synthesize the diverse array of matrix ...
Shapiro JA. 2007. Bacteria are small but not stupid
Shapiro JA. 2007. Bacteria are small but not stupid

... regulatory networks and sophisticated control processes that were unanticipated in the early days of this new approach to life (Alberts et al., 2002). Increasingly, computational rather than mechanical models are invoked to account for the operation of subcellular systems, the cell cycle, cellular d ...
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2.4 cell membrane transport

... pores in the membrane proteins this process is known as endocytosis. In this process the membrane itself wraps around the particle and pinches off a vesicle inside the cell. In this animation an ameba engulfs a food particle. ...
Cell Drawing Assignment Directions: Cells: Organelles:
Cell Drawing Assignment Directions: Cells: Organelles:

... On unlined paper draw all of the pictures listed below. Each picture should have a title, for example when drawing the mitochondria, the title at the top should read clearly “Mitochondria”. Each picture should be labeled. Each drawing should be in color. To save paper, you should cut unlined paper i ...
Effect of Nm blockers on Frog Rectus Abdomens Muscle
Effect of Nm blockers on Frog Rectus Abdomens Muscle

... moves 2 potassium ions in, thus in total removing one positive charge carrier from the intracellular space. • 2- Depolarization is a positive-going change in a cell's membrane potential, making it more positive, or less negative. In neurons and some other cells, a large enough depolarization may res ...
Cell movements driving neuruiation in avian embryos
Cell movements driving neuruiation in avian embryos

... morphogenetic cell behaviors, which occur both within the neural plate as well as within the surrounding tissues. A major task, which is not yet complete, has' been to catalog the relevant behaviors and to assess their respective roles in neurulation. This catalog reveals that neurulation is not an ...
Early Events in Annelid Regeneration: A Cellular Perspective
Early Events in Annelid Regeneration: A Cellular Perspective

... Synopsis The ability to regenerate extensive portions of the body is widespread among the phylum Annelida and this group includes some of the most highly regenerative animals known. Knowledge of the cellular and molecular basis of regeneration in this group is thus important for understanding how re ...
IL-13Ra1 Expression on b-Cell–Specific T Cells in NOD
IL-13Ra1 Expression on b-Cell–Specific T Cells in NOD

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Receptors and immune sensors: the complex entry path of human

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How Does Alpha-L-Polylactate™ in Cytomax® Work Faster than
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... APC and their receptor on T cells, CD28. Numerous studies have shown that B7/CD28 ligation enhances proliferation and IL-2 secretion by CD4⫹ T cells (13, 14). CD28 engagement is linked to cytoskeletal rearrangements upon TCR ligation (5, 15), and cytochalasin D blockade of these rearrangements aboli ...
Treatment of experimental arthritis by inducing immune tolerance
Treatment of experimental arthritis by inducing immune tolerance

... Mesenchymal stem cells (MSCs) are mesodermderived cells that reside in the stroma of solid organs and function as precursors of nonhematopoietic connective tissues. Besides their capacity to differentiate into mesenchymal and nonmesenchymal cell lineages (7,8) and their potential clinical applicatio ...
Teacher support material
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... AIM: To recap the most important differences between animal cells and plant cells. Procedure: Students draw, by copying, animal cell and plant cell images from a microscope and then make four sentences that recap the main differences between plant cells and animal cells by joining the two parts of t ...
Transport of substances in and out of the cell
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... It is the dispersion of atoms, ions or molecules by random thermal motion (kinetic energy) until these particles are equally distributed in the available space. For example , if some particles concentrated in the left side of a vessel, they will collide with each others, some may spread to the right ...
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Delamination of neural crest cells requires transient
Delamination of neural crest cells requires transient

... Interestingly, Dact2-expressing cells in the dorsal NT were intermingled with Dact2-negative cells (Fig. 3B). Thus, since Dact1/2 exhibited a conserved expression in the premigratory NC, we set out to test whether these proteins influence NC development. To study the role of Dact2 in chick embryos, ...
Polymer physics of intracellular phase transitions
Polymer physics of intracellular phase transitions

... Membrane-less compartments are condensed liquids An increasing body of work suggests that membrane-less organelles are multicomponent, viscous liquid-like structures that form via spontaneous phase transitions. These transitions occur on molecular supersaturation, which is achieved through regulated ...
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Immunology

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Eukaryote Variety

... Scanning electron micrograph of two human bone-forming cells (osteoblasts) crawling over crystals of the ceramic material,. monetite (CaHPO4). Monetite crystals are electrochemically deposited onto titanium making. the metal more compatible with the body. This can be used in applications such as art ...
Endoplasmosis and exoplasmosis: the evolutionary principles
Endoplasmosis and exoplasmosis: the evolutionary principles

... Ethical standards The accompanying manuscript does not include studies on humans or animals. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distributi ...
unresponsive to cell division control by polypeptide mating hormone
unresponsive to cell division control by polypeptide mating hormone

... arrest at start by a-factor (31); commonly, MA Ta cells produce a agglutinin constitutively but some are inducible by a-factor (27). To gain some insight into the specific roles played by the genes identified in this study, hormone production, hormone destruction, and agglutination were monitored in ...
In vitro–expanded human CD4 CD25 T-regulatory
In vitro–expanded human CD4 CD25 T-regulatory

... They are generated both through central thymic developmental mechanisms in pathogen-free mice12 and also arise by poorly defined peripheral generation or expansion mechanisms.13-15 It has been demonstrated that after antigen-specific activation, Treg cells can nonspecifically suppress proliferation ...
In This Issue - The Journal of Cell Biology
In This Issue - The Journal of Cell Biology

... conoid—a ribbon is easier to bend than The conoid is part of the apical a straw—but more work will be needed complex, the defining feature of the phylum Apicomplexa and to understand how the cell directs the assembly of this novel a structure thought to be involved in host cell invasion by structure ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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