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Analysis of Eukaryotic DNA Topoisomerases and
Analysis of Eukaryotic DNA Topoisomerases and

... strand through the transient nick (16). Type II topoisomerases are composed of two identical subunits with relative molecular masses of 170000 or 180000. They require ATP hydrolysis for catalytic activity and can alter DNA topology by creating transient double strand breaks, through which a second i ...
Print PDF
Print PDF

... The ability to form different types of biofilm enables bacteria to survive in a harsh or toxic environment. Different structures of biofilms are related to different surfaces and environment of bacterial growth. The aim of this study was analysis of the biofilm formation of 115 clinical uropathogeni ...
PDF + SI - The Journal of Immunology
PDF + SI - The Journal of Immunology

... Rumi Kaji, Junko Kiyoshima-Shibata, Masato Nagaoka, Masanobu Nanno, and Kan Shida ...
Metabolism of Tac - The Journal of Experimental Medicine
Metabolism of Tac - The Journal of Experimental Medicine

... studies. It exists in vivo as a transmembrane complete molecule (TM-Tac) on cell surfaces and as a truncated soluble form (sTac; slL2Rot), sTac has been used as a serum marker o f T cell activation in immune disorders and of tumor burden in Tac-expressing malignancies. In vivo, serum levels o f all ...
Active Transport of the Survival Motor Neuron Protein and
Active Transport of the Survival Motor Neuron Protein and

... and coiled (Cajal) bodies (Carvalho et al., 1999; Young et al., 2000). There have been extensive studies, in various cell lines of non-neuronal origin, on the targeting of SMN to these nuclear substructures and its function in spliceosome assembly and premRNA splicing (Paushkin et al., 2002). Despit ...
Costes et al.
Costes et al.

and Fibrinogen-Dependent Mechanisms Contribute to Platelet
and Fibrinogen-Dependent Mechanisms Contribute to Platelet

... Staphylococcus aureus can stimulate activation and aggregation of platelets, which are thought to be factors in the development of infective endocarditis. Previous studies have identified clumping factor A (ClfA) and fibronectin binding proteins A and B (FnBPA and FnBPB) as potent platelet aggregato ...
Biology I End-of-Course
Biology I End-of-Course

... According to their classification, which of the following animals are most closely related? A. Q and R This answer is not correct. The most closely related organisms share the greatest number of classification levels. Animals Q and R share only three classification levels, which is not the greatest ...
Auxin Transport Promotes Arabidopsis Lateral Root Initiation
Auxin Transport Promotes Arabidopsis Lateral Root Initiation

... were grown in the absence of NPA for 9 days and then transferred to new medium containing 0 or 10 ⫺7 M NAA. After another 3 days, the total number of emergent lateral roots was recorded (Figure 3). As expected, roots grown in the absence of NPA formed lateral roots (column A). Similarly, roots grown ...
ABSTRACT Title of Document:
ABSTRACT Title of Document:

... (Humphrey et al., 2004; Noy and Sklan, 1996; Noy and Sklan, 1999; Sklan and Noy, 2000; Zhang and Hillgartner, 2004). However, not much is known about metabolic adaptations in developing immune tissues. In chickens, lymphocyte development occurs during the embryonic to posthatch transition which invo ...
High-resolution imaging of cardiomyocyte behavior
High-resolution imaging of cardiomyocyte behavior

... a form of heart failure (Jenni et al., 1999). The trabeculae serve to increase myocardial mass before the formation of coronary vessels and, as such, have been shown to contribute to ventricular contractility; they are also necessary for the formation of the conduction system (Sedmera et al., 2003; ...
Response to Bacteria Excess Production of IL-12 and IL
Response to Bacteria Excess Production of IL-12 and IL

... from BM CD11b⫹ cells had an elongated spindle-like morphology. FACS analysis revealed that GM-M␾ expressed higher levels of MHC class II molecules and costimulatory molecules CD80 compared with M-M␾ (Fig. 1B and Table I). Expression of Gr-1 was also different between them; i.e., GM-M␾ but not M-M␾ e ...
Through form to function: root hair development and nutrient uptake
Through form to function: root hair development and nutrient uptake

... tip-focused [Ca21]cyt gradient reorients root hair growth towards The complex developmental processes outlined above lead to the the new gradient18. These observations are all consistent with a hair-like growth pattern of root hairs. This in turn increases the model whereby a localized increase in [ ...
premeiotic instability repeated sequences in neurospora crassa1 of
premeiotic instability repeated sequences in neurospora crassa1 of

... ~-4 × 107bp of DNA,of which <10%is repetitive (20, 41, 57). In contrast, higher plants and animals have genomes that are typically two orders of magnitude larger, and commonlyconsist of ~50%repetitive sequences. It is tempting to assume that the observed variability reflects different needs of the o ...
Cellulose Biosynthesis in Oomycetes
Cellulose Biosynthesis in Oomycetes

... the  plant,  fungal  and  Oomycete  cell  walls.    In  the  following  part,  cellulose  and  chitin  are  presented in more detail, especially their function, structure and biosynthesis. In the present  work,  some  functional  domains  of  Oomycete  cellulose  synthesizing  enzymes  have  been  i ...
Mouse Hoxa2 mutations provide a model for microtia and auricle
Mouse Hoxa2 mutations provide a model for microtia and auricle

... al., 2005; Schoenwolf and Larsen, 2009). Contrary to this prediction, we found that in E14.5 Wnt1::Cre;Hoxa2EGFP(lox-neo-lox)/+ mouse fetuses the EAC and its surrounding mesenchyme are entirely composed of Hoxa2–/EGFP– cells, and therefore not derived from the second arch (Fig. 1G,H,J). Moreover, we ...
Document
Document

... Eeso your support and prayers have kept me going always, and every time we talk or meet I am reassured I can make it through another day! Aya Helal thank you for believing in me all these years, you know me better than almost anyone else and having your faith has kept me strong! I love you my friend ...
The tale beyond the tail: histone core domain
The tale beyond the tail: histone core domain

... are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permission ...
Sensitive Interaction between Raptor a
Sensitive Interaction between Raptor a

... 1998; Isotani et al., 1999). The G␤L siRNA did not significantly affect the expression of S6K1 or ATM, or the phosphorylation state or amount of PKB1/Akt1, a downstream effector of PI 3-Kinase. Unlike a decrease in raptor expression (Kim et al., 2002), a reduction in G␤L expression did not also redu ...
Dystrophin is required for the formation of stable muscle attachments
Dystrophin is required for the formation of stable muscle attachments

... et al., 2002), are required for cholinergic signalling at neuromuscular junctions rather than muscle attachment or integrity. In Drosophila, mutations have been identified that affect the positioning and assembly of focal muscle attachments that resemble MTJs. Zinc finger transcription factors of th ...
Interaction of Cationic Peptides with Lipoteichoic Acid and Gram
Interaction of Cationic Peptides with Lipoteichoic Acid and Gram

... are potent inhibitors of gram-negative bacterial growth (22). The MICs of these peptides for E. coli ranged from 0.5 to 2 ␮g/ml, with the exception of CP208, which had an MIC of 32 ␮g/ml. In contrast to their strong activity against E. coli, we found that the antimicrobial activity of the peptides t ...
Protein phosphatase 1 down regulates ZYG
Protein phosphatase 1 down regulates ZYG

... isoforms are >85% identical and show largely overlapping roles, although some functional specialization has been identified [24]. C. elegans has four PP1 catalytic subunits: a single broadlyexpressed PP1β homolog, GSP-1, and three PP1α homologs, GSP-2, which is a ...
Energetic Crosstalk Between Organelles
Energetic Crosstalk Between Organelles

... the response remained, suggesting that most of the ATP used was of mitochondrial origin and not from external ATP. Thus, in normal hearts, mitochondrially produced ATP appeared far more effective in supporting SR calcium load than exogenous ATP, showing that mitochondria can effectively maintain hig ...
Ion Changes in Legume Root Hairs Responding to Nod
Ion Changes in Legume Root Hairs Responding to Nod

... Gehring et al. [1997]) showing that the alleged intracellular Ca2⫹ signal, which is elevated in response to Nod factor, declines to a basal level within a few seconds following the addition of EGTA. Correspondingly, the application of Ca2⫹ to the bathing medium caused a rapid increase in the signal. ...
Energetic Crosstalk Between Organelles
Energetic Crosstalk Between Organelles

... the response remained, suggesting that most of the ATP used was of mitochondrial origin and not from external ATP. Thus, in normal hearts, mitochondrially produced ATP appeared far more effective in supporting SR calcium load than exogenous ATP, showing that mitochondria can effectively maintain hig ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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