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Newman and Zahs, J Neurosci., 18:4022-8, 1998.
Newman and Zahs, J Neurosci., 18:4022-8, 1998.

... the underlying glial cells (Nedergaard, 1994; Parpura et al., 1994; Hassinger et al., 1995). A fascinating record showing the electrical excitation of a neuron, initiated by a glial Ca 21 wave, has also been reported (Hassinger et al., 1995). In these cell culture experiments, glial modulation of ne ...
Reprogramming glucose metabolism in cancer: can it be
Reprogramming glucose metabolism in cancer: can it be

... cancer metabolism in general, were not considered to be major branches of cancer biology. However, in the past 15 years, there has been a growing interest in cancer metabolism, particularly glucose metabolism in cancer cells; these topics have now become an integral part of cancer biology, similarly ...
Waite Study Guide for Quiz/Exam 1 Quiz 1
Waite Study Guide for Quiz/Exam 1 Quiz 1

... Monosaccharides absorbed without digestion; disaccharides and polysaccharides must be broken down by enzymes; humans lack enzyme required to digest cellulose; what happens if someone does not make the lactase enzyme? ...
Spatial Relationship between Transcription Sites and Chromosome
Spatial Relationship between Transcription Sites and Chromosome

... probes. Labeling of nascent RNA in combination with visualization of X chromosome and chromosome 19 territories was analyzed in diploid human female fibroblasts. In mammals, one X chromosome is transcriptionally inactivated during early development, while the other remains active (Lyon, 1961; Gartle ...
Complex networks orchestrate epithelial–mesenchymal transitions
Complex networks orchestrate epithelial–mesenchymal transitions

... mechanisms that cells use to regulate EMT. However, EMT is a dynamic process that involves many overlapping regulatory pathways as well as intra- and intercellular events, and interdisciplinary approaches are required to understand this complex regulation. For example, the dynamic formation and diss ...
Differences in Whole-Cell and Single
Differences in Whole-Cell and Single



... people are susceptible to whooping cough. The binding of B. pertussis to purified lactosylceramide in thin layer chromatography binding studies suggests that receptors for B. pertussis on cilia are galactose-glucose-containing glycolipids [60]. In marked contrast to M. pneumoniae and B. pertussis, w ...
Tissue: The Living Fabric
Tissue: The Living Fabric

... pass to adjacent cells Cells connected by hollow connexons Found in electrically excitable tissues (heart and smooth muscle) Ion passage from one cell to another helps to synchronize electrical activity ...
Splice variants` role in mediating different disease states in
Splice variants` role in mediating different disease states in

... Structure informs function, and this may be the evolutionary reason why alternative splicing, which is capable of generating different variants of the same protein, arise. But, given the energetic cost of generating different splice variants for testing their capability at a specific task, which inc ...
A primer on the mouse basal body
A primer on the mouse basal body

... early blastocyst stage, indicating that these embryonic mouse cells must build centrioles de novo [74, 75]. The de novo synthesis of centrioles in human cells is error prone, suggesting that the cell’s ability to construct a structurally accurate centriole may be facilitated by the existence of a pr ...
Resident in Normal Skin T Cells Are + The Vast Majority of CLA
Resident in Normal Skin T Cells Are + The Vast Majority of CLA

... T cells were isolated from explant cultures of normal human skin cultured in the presence of IL-2 (100 U/ml) and IL-15 (20 ng/ml) to induce proliferation of skin resident T cells (37). Cells were harvested at 21 days, and CD4⫹ CD25high and CD25low populations were separated by staining with anti-CD4 ...
The nuclear envelope in the plant cell cycle
The nuclear envelope in the plant cell cycle

... RCC1 (Zhang and Clarke, 2000). Recently, importin b has also been shown to be essential to the process by which nuclear pore assembly is initiated on chromatin (Rotem et al., 2009). ...
Nucleocytoplasmic interactions in the mouse embryo
Nucleocytoplasmic interactions in the mouse embryo

... (McGrath & Solter, 1983a) has greatly facilitated mammalian nuclear transplantation studies. In our initial description of this technique, 69 pronuclei were reciprocally transplanted between zygotes of mouse strains that differed in their coat colour phenotype. After transfer of resultant blastocyst ...
Development of the musculoskeletal system: meeting
Development of the musculoskeletal system: meeting

... presented data showing that the transcription factor Tcf4 (Tcf7L2) is strongly expressed in these fibroblasts. Using newly generated Tcf4GFPCre and tamoxifen-inducible Tcf4CreERT2 Cre driver lines in mouse, she showed that during development connective tissue regulates muscle fiber type and maturati ...
Harmonin Mutations Cause Mechanotransduction Defects in
Harmonin Mutations Cause Mechanotransduction Defects in

Practical Hints: Lysis of bacterial cells for plasmid purification
Practical Hints: Lysis of bacterial cells for plasmid purification

... material without centrifugation, reducing plasmid purification time considerably, particularly when large culture volumes or large numbers of samples are involved. Specialized modules are available for different scales of plasmid preparation, as well ...
Wing Venation and Flight
Wing Venation and Flight

... along the veins. The latter are essentially remnants of the body hemocoel. Even here the inner layers of the original body wall, the epidermis, and basement membrane, are sometimes much reduced or absent and the cuticle is thickened. The permanently appressed areas between the veins, i.e., the areas ...
Neuronal body size correlates with the number of nucleoli
Neuronal body size correlates with the number of nucleoli

... presentation. All images presented within each figure were identically adjusted for contrast, brightness, and dynamic resolution. The quantitative analysis of the number of nucleoli and CBs, as well as that of the nuclear distribution of CBs, was performed in squash preparations, double immunolabele ...
Induction of fungal cell wall stress
Induction of fungal cell wall stress

... niger was studied, in order to learn more about the possible mode of action. The transgenic strain that was used is a cell wall damage model. It shows induction of 1,3--D-glucan synthase gene by coupling it to a green fluorescent protein (GFP) marker encoding sequence. Induction of the gene encodin ...
Newly described pattern recognition receptors team up against
Newly described pattern recognition receptors team up against

... Necroptosis is a lytic type of cell death and requires the kinase activities of receptorinteracting protein 1 (RIP1) and RIP3. The discovery of necroptosis was prompted by the observation that tumour necrosis factor (TNF) treatment induces a necrotic type of cell death when caspase 8 activity is com ...
Active Uptake and Extravesicular Storage of m
Active Uptake and Extravesicular Storage of m

... radiopharmaceutical in this tumor category. The present study demonstrates for the first time extensive extravesicular storage of MIBG in a single in vitro model of human neuroblastoma. Obviously, nongranular storage will have an important, al though as yet unknown, impact on the biological half-lif ...
Title in Title Case and Bolded
Title in Title Case and Bolded

... phosphate (Ca8(HPO4)2(PO4)•5H2O, OCP, minor). Further annealing at 300℃, OCP disappeared and only HA was clearly identified on the HA/TiO2 coated specimens. Annealing above 500℃, composite coatings maintain HA crystal phase, didn’t occur phase transformation, as showed in Fig.1. The potentiodynamic ...
The paraventricular nucleus - Wyoming Scholars Repository
The paraventricular nucleus - Wyoming Scholars Repository

... • Interestingly, once NK3R has been activated, NK3R has been found not only within the cytoplasm but also within the nucleus. ...
About and Key Statistics - American Cancer Society
About and Key Statistics - American Cancer Society

... can cause normal cells to become cancerous. For several years we have known that mutations (damage or defects) to DNA can alter important genes that regulate cell growth. If these genes are damaged, excess growth may result in cancer formation. Analysis of DNA from uterine sarcomas has revealed seve ...
Regulation of ISWI -family of chromatin remodelling complexes
Regulation of ISWI -family of chromatin remodelling complexes

... has shed light into the function of its intrinsic domains. Interestingly, studies conducted in Drosophila and in yeast, demonstrated that the conserved ATPase domain has autonomous nucleosome remodelling activity while the ATPase adjacent domains have a regulatory function (Clapier and Cairns 2012; ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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