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Mast cells and basophils in acquired immunity
Mast cells and basophils in acquired immunity

... Studies in murine rodents, non-human primates, and humans indicate that many aspects of mast cell development and survival are critically regulated by stem cell factor (SCF), the ligand for the c-kit tyrosine growth factor receptor, which is expressed on the mast cell surface7-16'17. For example, lo ...
TLR-Dependent Th17 Activation Psoriasis
TLR-Dependent Th17 Activation Psoriasis

... chain in B cells and in DCs, thereby generating CLIP (11). Cathepsin K (CTSK) is highly expressed in osteoclasts, and is involved in the degradation of bone matrices, such as type I collagen (12). CTSK does not show Ag-processing capabilities, but facilitates the signaling of innate immune responses ...
question
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... •The process which generates genetically identical “buds” that break off to become a new organism is called/the process in which a fragment is broken off of an organism and grows into a new organism is called ...
1 METT-10, A Putative Methyltransferase, Inhibits Germ
1 METT-10, A Putative Methyltransferase, Inhibits Germ

... phospho-histone-3 (pH3, metaphase marker) nuclei were seen in mett-10(oz36) mutants, indicative of ectopic mitosis (Figure 1D-E). These cells were negative for the meiotic marker, GLD-1 (HANSEN et al. 2004b). Thus, these data argue that the mett-10(oz36) mutation causes proliferation of germ cells w ...
1 - UvA-DARE - University of Amsterdam
1 - UvA-DARE - University of Amsterdam

... Condorelli paper. Since then a consensus has been reached and the protein is now called GFAPδ (Condorelli et al., 1999; Middeldorp and Hol, 2011; Nielsen et al., 2002; Thomsen et al., 2013). Blechingberg and colleagues studied alternative splicing with a GFAP minigene construct and showed that the e ...
Treadmilling by FtsZ filaments drives peptidoglycan
Treadmilling by FtsZ filaments drives peptidoglycan

... (Fig. 3A, 3H, Movie SM4) or by depleting cells of Pbp2B (Fig. 3B, 3H, Movie SM5). We then tested if directional FtsAZ motion is due to filament treadmilling, as observed for FtsAZ assembled upon lipid bilayers in vitro (22). Consistent with treadmilling, sparse labeling of FtsZ or FtsA in cells demo ...
Quantitative profiling of initiating ribosomes in vivo - Shu
Quantitative profiling of initiating ribosomes in vivo - Shu

... correlation was partially due to reduced elongation speed under nutrient starvation that potentially increases the CDS ribosome occupancy (Supplementary Fig. 6). From the comprehensive data sets acquired from QTI-seq and Ribo-seq, we identified a large number of transcripts that underwent twofold ch ...
lithium-metal-polymer batteries: from the electrochemical
lithium-metal-polymer batteries: from the electrochemical

... In the LMP electrochemical cell, there is no secondary reaction comparable to electrolysis in liquid electrolyte systems during the recharge to limit the voltage at the end of charge. The electrochemical leakage current, although very small, is not equal from one cell to another. Over time, this dif ...
Melanotransferrin stimulates t-PA
Melanotransferrin stimulates t-PA

An improved system for competent cell preparation and
An improved system for competent cell preparation and

... This influx of water causes the cells to swell and is necessary for the uptake of DNA; the exact mechanism of this uptake is unknown. Our experiments have shown that different strains of E. coli have different growth characteristics, such as E. coli: XL1 blue, TG1 and DH5α, therefore, the optimal OD ...
Cellular transcription factors that interact with p6 promoter elements
Cellular transcription factors that interact with p6 promoter elements

... Fig. 2. Binding of cellular transcription factors to region D of the p6 promoter. EMSAs were performed with 32P-labelled oligonucleotides and 5 µg nuclear extracts prepared from HeLa cells (A) and from K562 and BJAB cells (B). After electrophoresis, the gels were exposed to X-ray film. The assignmen ...
Allogeneic T regulatory cell–mediated
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... Past work25 also showed delayed (MST ⫽ 48 days) rejection when grafting allogeneic skin from F1 mice as long as 1 haplotype was ...
chlamydomonas gymnogama and - The Journal of Cell Biology
chlamydomonas gymnogama and - The Journal of Cell Biology

... nants. It is possible that partial lysis of cell walls tein similar chemically to that of cell walls reinoccurs before and during the wall-shedding proc- forces the idea that what are at present undetectaess, as partial lysis of cell walls has been observed ble or relatively subtle differences in ch ...
Bacterial ancestry of actin and tubulin Fusinita van den Ent, Linda
Bacterial ancestry of actin and tubulin Fusinita van den Ent, Linda

... segregation that must resemble a mechanism almost as sophisticated as the eukaryotic mitotic spindle. A first indication of a cytoskeletal protein in prokaryotes is the resemblance between tubulin and FtsZ. These proteins are structurally related and both have a pivotal role in defining the division ...
The Dynamic Changes of Tonoplasts in Guard
The Dynamic Changes of Tonoplasts in Guard

... guard cells contained many small vacuoles when the stomata were closed. They were largely spherical and had a diameter of 1 to 5 mm (Fig. 1A). As stomata opening proceeded, the number of vacuoles decreased in each guard cell, but the size of vacuoles increased accordingly (Fig. 1, A–C). To facilitat ...
Chapter 5 pages/jg - Sinauer Associates
Chapter 5 pages/jg - Sinauer Associates

... being the first person to report seeing protists, in about 1675. In fact, Leeuwenhoek was the first to describe a number of microscopic aquatic life forms (e.g., rotifers), referring to them as animalcules (little animals). For nearly 200 years, protists were classified along with a great variety of ...
Movement of Ions and Electrogenesis in Microorganisms
Movement of Ions and Electrogenesis in Microorganisms

... the external medium, and that (Evat.) be- for both potassium and chloride are within tween the vacuole and the medium vary a few millivolts of the observed potential somewhat with species (Stolarek, 1968) difference across the tonoplast. It is posand with conditions (Findlay, et ah, sible, because o ...
The Vacuolar Proton-Cation Exchanger EcNHX1
The Vacuolar Proton-Cation Exchanger EcNHX1

... wall-localized proteins, and other defense constituents (Tsunezuka et al., 2005; Truman et al., 2007). This complexity is based on widely ramified signal cascades that use ubiquitous intermediates such as jasmonates (Blechert et al., 1995; Memelink et al., 2001), calcium ions, and salicylates and are ...
The retinoblastoma homolog RBR1 mediates localization of the
The retinoblastoma homolog RBR1 mediates localization of the

... into DNA replication phase (S-phase), we first tested whether rbr1 mutants are sensitive to hydroxyurea (HU, also called hydroxycarbamide). HU depletes the dNTP pools in a cell by inhibiting ribonucleotide reductase leading to an arrest of replication forks and subsequent DNA breakage (Yarbro, 1992) ...
animal phyla - Sakshieducation.com
animal phyla - Sakshieducation.com

... Which of the following character is evolved for the first time in phylum annelida? a) Organ-system level of body organization b) Bilateral symmetry c) Triploblastic d) Metameric segmentation Neural system in annelid consists of paired ganglia connected by lateral nerves to nerves cord. The nerve cor ...
In all vertebrate embryos examined so far, the first
In all vertebrate embryos examined so far, the first

... specific staining of the granules of granulocytes . We found this staining method to be strikingly efficient when applied to whole fixed zebrafish embryos, larvae, and even juvenile (over 1-month old) fish (Figure 1). At medium magnification, the staining nicely delineates the often amoeboid granulo ...
Chapter 7 final - Spiral
Chapter 7 final - Spiral

... lacking the active genes coding for proteinase A (PEP4) and proteinase B (PRB1). Previous work has shown that use of this strain has resulted in higher expression levels of GPCRs, most probably as a result of reduced proteolytic degradation (2, 3). As mentioned in Chapter 4, generation of the P. pas ...
DV axis HT12
DV axis HT12

...  Maternal effect genes  Dorsal/Ventral patterning  Multiple signalling pathways are involved in setting up D-V patterning. These pathways are used in different contexts during development and are highly conserved in different organisms. ...
The Social Lives of Microbes
The Social Lives of Microbes

... other individuals have posed particular problems for evolutionary biologists because although the cost of a cooperative behavior may be very obvious, the benefits are often obscure. We do not discuss the use and misuse of terms such as cooperation and altruism, as we have recently covered that in det ...
Cell Structure and Function
Cell Structure and Function

... • What kind of mechanisms and adaptations do cells have to survive in a variety of conditions. – For example, some animals and single-celled organisms can survive in hypotonic environments. ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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