LPS- or Pseudomonas aeruginosa- mediated activation of
... (Manders, Verbeek & Aten, 1993). Four independent experiments were performed in triplicates for each combination of PUFA supplementation and stimulation of cells. ...
... (Manders, Verbeek & Aten, 1993). Four independent experiments were performed in triplicates for each combination of PUFA supplementation and stimulation of cells. ...
Ferrara et al, Nat Med 2003 - Kashyap Memorial Eye Hospital
... • All types of RVO are multifactorial in origin and their pathology includes one or more of the following1 – narrowing of the retinal vein due to external pressures • sclerotic adjacent structures • secondary endothelial proliferation ...
... • All types of RVO are multifactorial in origin and their pathology includes one or more of the following1 – narrowing of the retinal vein due to external pressures • sclerotic adjacent structures • secondary endothelial proliferation ...
Comparison of test tube, gel column agglutination and solid
... DIIHA, while uncommon, can be potentially very serious and even fatal. Drug dependent antibodies can be mistaken for warm or cold-type autoantibodies or alloantibody related to a delayed hemolytic transfusion reaction.7,10,11 Testing for drug-dependent antibodies is determined by analyzing the abili ...
... DIIHA, while uncommon, can be potentially very serious and even fatal. Drug dependent antibodies can be mistaken for warm or cold-type autoantibodies or alloantibody related to a delayed hemolytic transfusion reaction.7,10,11 Testing for drug-dependent antibodies is determined by analyzing the abili ...
Challenges to our current view on chloroplasts
... between bacteria and eukaryotes is the presence of a cytoskeleton only in the latter. It seemed plausible that small cells like bacteria do not need structural elements, and they appeared as ‘plasma-filled tiny droplets’, although microbiologists were well aware of the different cell shapes bacteria ...
... between bacteria and eukaryotes is the presence of a cytoskeleton only in the latter. It seemed plausible that small cells like bacteria do not need structural elements, and they appeared as ‘plasma-filled tiny droplets’, although microbiologists were well aware of the different cell shapes bacteria ...
Cytokinesis in Tobacco BY-2 and Root Tip Cells: A New Model of
... cell wall between daughter cells. This process is accomplished by the formation of the phragmoplast that not only builds the new plate but spatially orients it within the cell relative to the whole plant or organ axis. The phragmoplast of higher plant cells has been described as consisting of three ...
... cell wall between daughter cells. This process is accomplished by the formation of the phragmoplast that not only builds the new plate but spatially orients it within the cell relative to the whole plant or organ axis. The phragmoplast of higher plant cells has been described as consisting of three ...
Structural Basis for Type VI Secretion Effector Recognition
... ten amino acid intervals along the length of the protein. In the four cases wherein one of these positions already encoded an alanine, only one substitution was made. Toxicity of the mutant alleles was determined by monitoring the effect of their ectopic expression on the growth of PAO1 Dtse2 Dtsi2. ...
... ten amino acid intervals along the length of the protein. In the four cases wherein one of these positions already encoded an alanine, only one substitution was made. Toxicity of the mutant alleles was determined by monitoring the effect of their ectopic expression on the growth of PAO1 Dtse2 Dtsi2. ...
Shaping the metaphase chromosome: coordination of cohesion and
... is a central player in chromosome condensation, a process that initiates at the onset of mitosis. The main focus of this review is to discuss how the mitotic metaphase chromosome is assembled and shaped by a precise balance between the cohesion and condensation machineries. We argue that, in differe ...
... is a central player in chromosome condensation, a process that initiates at the onset of mitosis. The main focus of this review is to discuss how the mitotic metaphase chromosome is assembled and shaped by a precise balance between the cohesion and condensation machineries. We argue that, in differe ...
Multiple mechanisms determine the order of APC/C substrate
... ubiquitination in vitro (Holt et al., 2008; Holt et al., 2009). Cdc14 dephosphorylates these sites in vitro. Given that securin degradation leads to Cdc14 activation indirectly through separase, these results suggested the existence of positive feedback in securin degradation. Although this phosphor ...
... ubiquitination in vitro (Holt et al., 2008; Holt et al., 2009). Cdc14 dephosphorylates these sites in vitro. Given that securin degradation leads to Cdc14 activation indirectly through separase, these results suggested the existence of positive feedback in securin degradation. Although this phosphor ...
mast cells and basophils
... with a few short blunt projections, but no evidence of the long surface projections of the lung mast cell [54, 57]. The nucleus shows marked chromatin condensation, is lobular, and more than one lobe may be seen in some sections (fig. 1). The cytoplasm has numerous granules, with visible mitochondri ...
... with a few short blunt projections, but no evidence of the long surface projections of the lung mast cell [54, 57]. The nucleus shows marked chromatin condensation, is lobular, and more than one lobe may be seen in some sections (fig. 1). The cytoplasm has numerous granules, with visible mitochondri ...
A Novel Recombinant Plasma Membrane
... ATP release triggered by receptor-directed stimuli, we challenged the HEK293-pmeLUC cells with various agonists of G protein-coupled receptors (e.g., carbachol, histamine, bradykinin), obtaining negligible ATP release (unpublished data). Early experiments from our and other laboratories had previous ...
... ATP release triggered by receptor-directed stimuli, we challenged the HEK293-pmeLUC cells with various agonists of G protein-coupled receptors (e.g., carbachol, histamine, bradykinin), obtaining negligible ATP release (unpublished data). Early experiments from our and other laboratories had previous ...
Cytokinesis in Tobacco BY-2 and Root Tip Cells: A
... cell wall between daughter cells. This process is accomplished by the formation of the phragmoplast that not only builds the new plate but spatially orients it within the cell relative to the whole plant or organ axis. The phragmoplast of higher plant cells has been described as consisting of three ...
... cell wall between daughter cells. This process is accomplished by the formation of the phragmoplast that not only builds the new plate but spatially orients it within the cell relative to the whole plant or organ axis. The phragmoplast of higher plant cells has been described as consisting of three ...
10th Grade Science Learning Targets
... I can describe different cellular processes and how they are important for homeostasis (balance) of all organisms. I can describe what homeostasis is and the processes necessary to maintain it (e.g., cellular transport (movement) of materials and synthesis (production) of new materials) I can explai ...
... I can describe different cellular processes and how they are important for homeostasis (balance) of all organisms. I can describe what homeostasis is and the processes necessary to maintain it (e.g., cellular transport (movement) of materials and synthesis (production) of new materials) I can explai ...
L egionella pneumophila
... 1 a). In these colonies, bacterial cells more than 20 pm in length were common (Fig. 1 b). The major fracture plane occurred through the hydrophobic region of the plasma (inner) membrane revealing both the protoplasmic (PFim)and extracellular (EF,,) faces (Fig. 1 c), the PF,, being seen more often. ...
... 1 a). In these colonies, bacterial cells more than 20 pm in length were common (Fig. 1 b). The major fracture plane occurred through the hydrophobic region of the plasma (inner) membrane revealing both the protoplasmic (PFim)and extracellular (EF,,) faces (Fig. 1 c), the PF,, being seen more often. ...
Nervous system
... Ependymal cells : the thin epithelial membrane lining the ventricular system of the brain and the spinal cord. It is involved in the production of cerebrospinal fluid (CSF). ...
... Ependymal cells : the thin epithelial membrane lining the ventricular system of the brain and the spinal cord. It is involved in the production of cerebrospinal fluid (CSF). ...
The Physiology of Gibberellin-Induced Elongation
... system. Experiments have been conflned largely to studies with whole plants (I, 2) and to studies with excised sections which show a very limited growth response to GA (3,4) or some dependence on, or response to, auxins (3,5,6). Among the conceptuallirnitations to progress in elucidating the mechani ...
... system. Experiments have been conflned largely to studies with whole plants (I, 2) and to studies with excised sections which show a very limited growth response to GA (3,4) or some dependence on, or response to, auxins (3,5,6). Among the conceptuallirnitations to progress in elucidating the mechani ...
Life on and in stone – an endless story
... has also made progress. One factor is the awareness not only of biologically initiated chemical but also physical and mechanical damage functions. Another line of evolution of techniques and application proposals is the application of biocidal chemicals. However, in the past 20 years, these have bee ...
... has also made progress. One factor is the awareness not only of biologically initiated chemical but also physical and mechanical damage functions. Another line of evolution of techniques and application proposals is the application of biocidal chemicals. However, in the past 20 years, these have bee ...
Presence of Human Papillomavirus Type 18 DNA in Vulvar
... To ascertain whether a region of HPV-18 genome was consistently retained during integration, as has been found for HPV-16 (Choo et al., 1987), hybridization experiments with subgenomic probes of HPV-18 DNA were done as shown in Fig. 3. Owing to the low amount of DNA extracted from small biopsies we ...
... To ascertain whether a region of HPV-18 genome was consistently retained during integration, as has been found for HPV-16 (Choo et al., 1987), hybridization experiments with subgenomic probes of HPV-18 DNA were done as shown in Fig. 3. Owing to the low amount of DNA extracted from small biopsies we ...
characterisation of amino acid transport in red blood cells of a
... Fincham et al. 1985a, 1987a). These transporters share system ASOs selectivity for neutral amino acids of intermediate size, are inhibited by the Na + site inhibitor harmaline, but do not require cations for activity (Young etal. 1988). Inherited deficiencies of asc are relatively common in some hor ...
... Fincham et al. 1985a, 1987a). These transporters share system ASOs selectivity for neutral amino acids of intermediate size, are inhibited by the Na + site inhibitor harmaline, but do not require cations for activity (Young etal. 1988). Inherited deficiencies of asc are relatively common in some hor ...
Is the Development of Orientation Selectivity Instructed by Activity?
... Movshon and Van Sluyters, 1981; Fregnac and Imbert, 1984) do not bear on the role of activity in establishing orientation selectivity. The role of activity in development of orientation selectivity has been better studied in ferrets, which are born at an earlier stage in cortical development. The no ...
... Movshon and Van Sluyters, 1981; Fregnac and Imbert, 1984) do not bear on the role of activity in establishing orientation selectivity. The role of activity in development of orientation selectivity has been better studied in ferrets, which are born at an earlier stage in cortical development. The no ...
Computational modelling of mitotic exit in budding yeast: the role of
... A mathematical model with reduced number of components was developed previously for the budding yeast ME transition from metaphase (i.e. high Cdk1 activity) to G1 (i.e. low Cdk1 activity state) [11,12]. Queralt’s model (QM) centres around the non-proteolytic function of separase (Esp1), which trigge ...
... A mathematical model with reduced number of components was developed previously for the budding yeast ME transition from metaphase (i.e. high Cdk1 activity) to G1 (i.e. low Cdk1 activity state) [11,12]. Queralt’s model (QM) centres around the non-proteolytic function of separase (Esp1), which trigge ...
Activity-based probes that target diverse cysteine protease families
... as well as to forms of these proteases with and without their N-terminal peptides22, 23. However, high background signal from bVAD-FMK obscured visualization of labeled caspase-9 (at 35 kDa), whereas bEVD-AOMK labeling of caspase-9 could be clearly visualized (Fig. 3b). Together these results sugges ...
... as well as to forms of these proteases with and without their N-terminal peptides22, 23. However, high background signal from bVAD-FMK obscured visualization of labeled caspase-9 (at 35 kDa), whereas bEVD-AOMK labeling of caspase-9 could be clearly visualized (Fig. 3b). Together these results sugges ...
2 - Liu Lab
... To explore non-oncogene addiction to BRD4 in breast cancer, we studied a series of BET bromodomain inhibitors (BBI) across breast cell lines reflecting transcriptionally defined breast cancer subtypes: luminal, HER2+ and TNBC2,10, as well as MCF10A and MCF12A basal/ mesenchymal immortalized mammary ...
... To explore non-oncogene addiction to BRD4 in breast cancer, we studied a series of BET bromodomain inhibitors (BBI) across breast cell lines reflecting transcriptionally defined breast cancer subtypes: luminal, HER2+ and TNBC2,10, as well as MCF10A and MCF12A basal/ mesenchymal immortalized mammary ...
Embryonic Stem Cell Culture Conditions Support Distinct States
... this heterogeneity is dynamic, perhaps more dynamic than the blastocyst from which they are derived. However, does this heterogeneity reflect the endogenous cell populations that arise in normal blastocyst development? The functional potential of ESCs can be assessed using a number of different appr ...
... this heterogeneity is dynamic, perhaps more dynamic than the blastocyst from which they are derived. However, does this heterogeneity reflect the endogenous cell populations that arise in normal blastocyst development? The functional potential of ESCs can be assessed using a number of different appr ...
Mitochondrial Dynamics and the ER: The Plant Perspective
... A model for the mixing and unmixing of mitochondrial content was proposed, describing a separation of dysfunctional mitochondria from the pool of fusing mitochondria, and their targeting to autophagosomes (Twig et al., 2008b). In mammalian cells mitochondrial fusion triggers fission which in turn is ...
... A model for the mixing and unmixing of mitochondrial content was proposed, describing a separation of dysfunctional mitochondria from the pool of fusing mitochondria, and their targeting to autophagosomes (Twig et al., 2008b). In mammalian cells mitochondrial fusion triggers fission which in turn is ...