Chromatin folding – from biology to polymer models and back
... chromatin fibre forms loops is already several decades old, but only about 10 years ago the notion grew that looping has a direct role in gene regulation (Bulger and Groudine, 1999). However, only recently it has become possible to directly measure chromatin– chromatin interactions (i.e. looping) by ...
... chromatin fibre forms loops is already several decades old, but only about 10 years ago the notion grew that looping has a direct role in gene regulation (Bulger and Groudine, 1999). However, only recently it has become possible to directly measure chromatin– chromatin interactions (i.e. looping) by ...
Mitochondrial Dynamics and the ER: The Plant Perspective
... A model for the mixing and unmixing of mitochondrial content was proposed, describing a separation of dysfunctional mitochondria from the pool of fusing mitochondria, and their targeting to autophagosomes (Twig et al., 2008b). In mammalian cells mitochondrial fusion triggers fission which in turn is ...
... A model for the mixing and unmixing of mitochondrial content was proposed, describing a separation of dysfunctional mitochondria from the pool of fusing mitochondria, and their targeting to autophagosomes (Twig et al., 2008b). In mammalian cells mitochondrial fusion triggers fission which in turn is ...
Embryonic Stem Cell Culture Conditions Support Distinct States
... this heterogeneity is dynamic, perhaps more dynamic than the blastocyst from which they are derived. However, does this heterogeneity reflect the endogenous cell populations that arise in normal blastocyst development? The functional potential of ESCs can be assessed using a number of different appr ...
... this heterogeneity is dynamic, perhaps more dynamic than the blastocyst from which they are derived. However, does this heterogeneity reflect the endogenous cell populations that arise in normal blastocyst development? The functional potential of ESCs can be assessed using a number of different appr ...
genome size, leaf, fruit and seed traits – taxonomic
... was calculated as the target peak mean, divided by the internal standard peak mean, and multiplied by the amount of 2C DNA of P. hybrida standard. The coefficients of variation of the 2C DNA content were estimated for all the samples of the studied Nasturtium species. The 1C genome size was calculat ...
... was calculated as the target peak mean, divided by the internal standard peak mean, and multiplied by the amount of 2C DNA of P. hybrida standard. The coefficients of variation of the 2C DNA content were estimated for all the samples of the studied Nasturtium species. The 1C genome size was calculat ...
Effect of Natural Sunlight on Bacterial Activity and Differential
... We studied the effects of natural sunlight on heterotrophic marine bacterioplankton in short-term experiments. We used a single-cell level approach involving flow cytometry combined with physiological probes and microautoradiography to determine sunlight effects on the activity and integrity of the ...
... We studied the effects of natural sunlight on heterotrophic marine bacterioplankton in short-term experiments. We used a single-cell level approach involving flow cytometry combined with physiological probes and microautoradiography to determine sunlight effects on the activity and integrity of the ...
EDC Skin Care Ingredients Glossary
... magnesium ions. In the absence of vitamin D, dietary calcium is not absorbed at all efficiently. Vitamin D stimulates the expression of a number of proteins involved in transporting calcium from the lumen of the intestine, across the epithelial cells and into blood. The best studied of these calcium ...
... magnesium ions. In the absence of vitamin D, dietary calcium is not absorbed at all efficiently. Vitamin D stimulates the expression of a number of proteins involved in transporting calcium from the lumen of the intestine, across the epithelial cells and into blood. The best studied of these calcium ...
Graft Rejection following Burn Injury Mechanism for Effective
... obstacle in controlling chronic allograft rejection and inducing tolerance following solid organ transplantation (17, 18). Similarly in sepsis, while increased interest in innate immunity (19), including dendritic cells, macrophages, as well as other T cell populations, including regulatory CD4⫹ T c ...
... obstacle in controlling chronic allograft rejection and inducing tolerance following solid organ transplantation (17, 18). Similarly in sepsis, while increased interest in innate immunity (19), including dendritic cells, macrophages, as well as other T cell populations, including regulatory CD4⫹ T c ...
Dynamics of Cell Movement and Tissue Motion in Gastrulation and
... Genetic and Generic Mechanisms . . . . . . . . . . . . . . . . . ...
... Genetic and Generic Mechanisms . . . . . . . . . . . . . . . . . ...
Infectious Diseases in Obstetrics and Gynecology Vol. 2008, Article
... [17]. Following these guidelines successfully treats 60% of BV cases, but 20% of these cases return with highly developed antibiotic resistances [18–20]. In such cases, it would be extremely desirable to have an alternative form of treatment that could fully eradicate the infection. ...
... [17]. Following these guidelines successfully treats 60% of BV cases, but 20% of these cases return with highly developed antibiotic resistances [18–20]. In such cases, it would be extremely desirable to have an alternative form of treatment that could fully eradicate the infection. ...
About Basal and Squamous Cell Skin Cancer
... Keratoacanthomas are dome-shaped tumors that are found on sun-exposed skin. They may start out growing quickly, but their growth usually slows down. Many keratoacanthomas shrink or even go away on their own over time without any treatment. But some continue to grow, and a few may even spread to othe ...
... Keratoacanthomas are dome-shaped tumors that are found on sun-exposed skin. They may start out growing quickly, but their growth usually slows down. Many keratoacanthomas shrink or even go away on their own over time without any treatment. But some continue to grow, and a few may even spread to othe ...
Regulation of tubulin heterodimer partitioning during interphase and
... phenotype by overexpressing the wild type Op18 protein. Thus, either excessive levels of wild type Op18 or normal levels of mutated hyper-active Op18 seems likely to contribute to tumor progression by exacerbating chromosomal instability. ...
... phenotype by overexpressing the wild type Op18 protein. Thus, either excessive levels of wild type Op18 or normal levels of mutated hyper-active Op18 seems likely to contribute to tumor progression by exacerbating chromosomal instability. ...
Division, and Morphogenesis in Plants
... Ben Scheres and Renze Heidstra Department of Molecular Cell Biology ...
... Ben Scheres and Renze Heidstra Department of Molecular Cell Biology ...
Interferon Gamma-Treated Keratinocytes Activate T Cells in the
... Similar results were obtained with another superantigen staphylococcal enterotoxin A. As expected due to both MHC restriction and the limitations with the keratinocytes as accessory cells, incubation of nominal antigen with MHC class II+ keratinocytes and T cells did not result in proliferation of T ...
... Similar results were obtained with another superantigen staphylococcal enterotoxin A. As expected due to both MHC restriction and the limitations with the keratinocytes as accessory cells, incubation of nominal antigen with MHC class II+ keratinocytes and T cells did not result in proliferation of T ...
Hereditary effects of radiation
... 3. The male is more radiosensitive than females. 4. The genetic effects of a given radiation dose can be reduced greatly if a time interval is allowed between exposure and conception. 5. The estimate of the doubling dose adopted by BEIR V and UNSCEAR 88 is 1 Gy. ...
... 3. The male is more radiosensitive than females. 4. The genetic effects of a given radiation dose can be reduced greatly if a time interval is allowed between exposure and conception. 5. The estimate of the doubling dose adopted by BEIR V and UNSCEAR 88 is 1 Gy. ...
exportin-5 mediates their nuclear export
... paradigm of gene regulation, leaving us with numerous exciting questions regarding what these molecules do and how they originate. A model for miRNA biogenesis has emerged recently, yet several key factors – including the identity of the miRNA nuclear export receptor – remained unknown. However, rec ...
... paradigm of gene regulation, leaving us with numerous exciting questions regarding what these molecules do and how they originate. A model for miRNA biogenesis has emerged recently, yet several key factors – including the identity of the miRNA nuclear export receptor – remained unknown. However, rec ...
Cytokine receptor signaling through the Jak–Stat–Socs pathway in
... loss-of-function Stat1 (L706S) mutation are also susceptible to mycobacterial infection (Dupuis et al., 2001), consistent with the involvement of this Stat in both types I and II IFNR signaling. Finally, a spontaneously occurring murine Tyk2 mutant is highly sensitive to Toxoplasma gondii infection, ...
... loss-of-function Stat1 (L706S) mutation are also susceptible to mycobacterial infection (Dupuis et al., 2001), consistent with the involvement of this Stat in both types I and II IFNR signaling. Finally, a spontaneously occurring murine Tyk2 mutant is highly sensitive to Toxoplasma gondii infection, ...
Differential function of Listeria monocytogenes listeriolysin O and
... grown in the presence of IPTG (pre-induced) were used to infect a monolayer of CellTracker™ Blue-labelled mBMDM in the absence of inducer. In the absence of continued IPTG induction, we speculated that intracellular LLO production would cease (Table 1). At 6 h post infection, the infected mBMDM were ...
... grown in the presence of IPTG (pre-induced) were used to infect a monolayer of CellTracker™ Blue-labelled mBMDM in the absence of inducer. In the absence of continued IPTG induction, we speculated that intracellular LLO production would cease (Table 1). At 6 h post infection, the infected mBMDM were ...
November 2012 - An error occurred.
... improved wood.” It’s not that wood is faulty for trees, but in construction, builders would like to prevent moisture absorption and warping. The article says, “wood’s position as a mainstay building material over the centuries results from a combination of desirable factors, including surprising str ...
... improved wood.” It’s not that wood is faulty for trees, but in construction, builders would like to prevent moisture absorption and warping. The article says, “wood’s position as a mainstay building material over the centuries results from a combination of desirable factors, including surprising str ...
The hypersensitive response is associated with host and nonhost
... growing lesions (1.2 mm/day). Plants with lower levels of partial resistance, such as S. arnezii ´ hondelmannii72, displayed higher IEs (86%) and LGRs (2.4 mm/ day). Susceptible clones became fully infected and showed fast expanding lesions (up to 4.0 mm/day). In general, IE and LGR appeared to be c ...
... growing lesions (1.2 mm/day). Plants with lower levels of partial resistance, such as S. arnezii ´ hondelmannii72, displayed higher IEs (86%) and LGRs (2.4 mm/ day). Susceptible clones became fully infected and showed fast expanding lesions (up to 4.0 mm/day). In general, IE and LGR appeared to be c ...
Topical aldose reductase inhibitor for correcting
... inhibitor, CT-1 12. Similarly, topical application of several AR inhibitors has been shown to be effective in preventing or reversing the corneal endothelial changes in diabetic rats34 and galactosaemic dogs.5 The regeneration of the comeal endothelium was also found to be delayed in galactosaemic r ...
... inhibitor, CT-1 12. Similarly, topical application of several AR inhibitors has been shown to be effective in preventing or reversing the corneal endothelial changes in diabetic rats34 and galactosaemic dogs.5 The regeneration of the comeal endothelium was also found to be delayed in galactosaemic r ...
Denitrification of water in a microbial fuel cell (MFC) using seawater
... 39% higher compared to PBS (Fan et al., 2007). There are also reports on the direct use of low-conductivity waters like groundwater sources without buffer addition, and with a high nitrate content, and their subsequent denitrification. Pous et al. (2013) observed a 64% removal efficiency of nitrate ...
... 39% higher compared to PBS (Fan et al., 2007). There are also reports on the direct use of low-conductivity waters like groundwater sources without buffer addition, and with a high nitrate content, and their subsequent denitrification. Pous et al. (2013) observed a 64% removal efficiency of nitrate ...
Mast cells and basophils in acquired immunity
... Studies in murine rodents, non-human primates, and humans indicate that many aspects of mast cell development and survival are critically regulated by stem cell factor (SCF), the ligand for the c-kit tyrosine growth factor receptor, which is expressed on the mast cell surface7-16'17. For example, lo ...
... Studies in murine rodents, non-human primates, and humans indicate that many aspects of mast cell development and survival are critically regulated by stem cell factor (SCF), the ligand for the c-kit tyrosine growth factor receptor, which is expressed on the mast cell surface7-16'17. For example, lo ...
STEROIDOGENESIS IN THECA CELLS OF CHICKEN FOLLICLES
... pieces, and incubated for 60 min in Medium 199 containing 10mM Hepes and 0.2% collagenase with mechanical disruption of tissue at 15 min interval with a syringe. The cell suspensions of theca interna and theca externa were filtered through a nylon gauze (60µm mesh) and centrifuged at 400 X g for 10 ...
... pieces, and incubated for 60 min in Medium 199 containing 10mM Hepes and 0.2% collagenase with mechanical disruption of tissue at 15 min interval with a syringe. The cell suspensions of theca interna and theca externa were filtered through a nylon gauze (60µm mesh) and centrifuged at 400 X g for 10 ...