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Good news in the nuclear envelope: loss of lamin A might be a gain
Good news in the nuclear envelope: loss of lamin A might be a gain

... of the rather sophisticated sequence of prelamin A posttranslational modifications? It has generally been assumed that farnesylation of lamin A is important not only for its targeting to the nuclear periphery, but also for bringing lamin C to the lamina via interactions between lamin A and lamin C a ...
Running title: Mode of Bactericidal Action of the Jatropha curcas
Running title: Mode of Bactericidal Action of the Jatropha curcas

... General linear models (GLM) procedure of SAS in a completely randomized design (CRD) was used to analyse the data and the means were compared with Duncan's Multiple Range test. The differences were considered significant when the p value was ...
05 Keim
05 Keim

... called magnetosomes. The bacterial cells may also have phosphorus-containing granules, sulfur globules, or polyhydroxyalkanoate inclusions. In the present study, the ultrastructure and elemental composition of intracellular inclusions from uncultured magnetotactic bacteria collected in a marine envi ...
A 55-Kilodalton Accessory Factor Facilitates Vitamin D Receptor
A 55-Kilodalton Accessory Factor Facilitates Vitamin D Receptor

... presence of NAF activity in cellular extacts. As seen in Fig. 1, while cellular extracts containing this activity do not bind to a VDRE probe in the absence of VDR, the addition of this protein, either from crude yeast cytosols or as purified VDR, leads to the clear demonstration of a protein-DNA co ...
Genetic analysis of seed coat development in Arabidopsis
Genetic analysis of seed coat development in Arabidopsis

... endosperm, the seed coat is not directly involved in the fertilization process. Therefore, one or more events during or following fertilization must signal the seed coat to develop coordinately with the other tissues. Two recent studies have used mutants to provide evidence for the influence of the ...
Kingdom Protozoa
Kingdom Protozoa

... • Flagellated protozoans are singlecelled protists covered by a pellicle (proteins that help cells retain shape) • They swim in lakes, seas, and the body fluids of animals • They are typically heterotrophic and reproduce asexually by binary ...
E-cadherin controls β-catenin and NF
E-cadherin controls β-catenin and NF

... upregulates fibronectin and LEF1 RNA levels. Cells expressing an siRNA specific to E-cadherin or a scrambled control (Irr) were cultured until confluence, and E-cadherin and actin levels were determined by western blot (F). In parallel, fibronectin, LEF1 or HPRT RNA content were determined in these ...
Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system.
Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system.

... are delivered along with additional information that can be used by the host to distinguish pathogenic from nonpathogenic microbes and thereby guide the ensuing innate immune response. Pathogen-Associated Molecular Patterns Dual Recognition of PAMPs A relatively select group of bacterial molecules a ...
Cell delamination in the mesencephalic neural fold
Cell delamination in the mesencephalic neural fold

... of ectodermal and mesodermal markers, such as platelet-derived growth factor receptor alpha (PDGFRα) (Weston et al., 2004). This idea is supported by the finding that these cells were found in established mouse strains that label the ectomesenchyme (Breau et al., 2008). Studies have yet to directly ...
but Differ in Other Key Biological Activities Both Th1 and Th17 Are
but Differ in Other Key Biological Activities Both Th1 and Th17 Are

... Tg mice from each line were mated to produce (FVB/N ⫻ B10.BR) F1 hybrids that express HEL, HEL-specific TCR, or both or neither transgene (“wild type” (WT)). The F1 hybrids containing the different transgenes were used for all experiments. For all adoptive transfer studies, reactivated cells from 3A ...
PDF
PDF

... undergrowth phenotype (Bhattacharya and Baker, 2011; AndradeZapata and Baonza, 2014), which is the expected phenotype if the sequestration of Da by Emc is required to promote tissue growth. We conducted a directed yeast two-hybrid assay to assess the strength of the interaction between Emc and Da, a ...
B. fragilis ΔPSA
B. fragilis ΔPSA

... Our intestinal tract is a nutrient-rich environment packed with up to 100 trillion (1014) microbes. The vast majority reside in our colon where densities approach 1011–1012 cells/ml, the highest recorded for any microbial habitat Today, there are 6.5 billion humans living on Earth. Together, we ...
Musculoskeletal
Musculoskeletal

... • Exclude other lesions which may have giant cells including brown tumour of hyperparathyroidism, gingival epulis, fibrous cortical defect, aneurysmal bone cyst, chondroblastoma. Carcinoma and soft tissue sarcoma may sometimes have prominent giant cells but rarely cause diagnostic difficulties • Occ ...
microbiology-1st-edition-wessner-test-bank
microbiology-1st-edition-wessner-test-bank

... Learning Objective: LO 2.4 Identify the components of the bacterial cytoplasmic membrane and cell wall, and the functions of these structures. Section Reference: Section 2.4 The cell envelope 19) What conditions must be met in order for an “active transport system” to transport of a nutrient into a ...
nerve pathways and reflex siphon withdrawal in the surf clam
nerve pathways and reflex siphon withdrawal in the surf clam

... somata of efferent neurons having large fibres to the siphons occur in specific identifiable regions, the pallial integrating centres. Axons of individual cells in these regions are distributed to one or (rarely) two of the three main branches of the posterior pallial nerves on the side of origin; t ...
Unusual chromosome structure of fission yeast DNA in mouse cells
Unusual chromosome structure of fission yeast DNA in mouse cells

... the fragile X mutation correlates with expansion and methylation of a simple trinucleotide repeat and delayed DNA replication of the surrounding chromosomal region (Hansen et al., 1993). A more subtle form of differentiation of mammalian euchromatin is that manifest by chromosome banding. The bioche ...
Protists
Protists

... Paramecium (what we are looking for in pond water) can actually reproduce 2 ways.  Normally they reproduce  using binary fission.  If they get stressed, they will find a partner and reproduce sexually.  In this case, it  requires 2 parents.  The offspring will have parts of both parents in its chrom ...
Analysis of Kinase Effects on Viral Replication of the Papillomavirus
Analysis of Kinase Effects on Viral Replication of the Papillomavirus

Dispersal of Golgi matrix proteins during mitotic Golgi
Dispersal of Golgi matrix proteins during mitotic Golgi

... larger than those previously reported in other cell types (Shima et al., 1997; Jesch et al., 2001), our analysis indicated that these clusters only represented a small fraction of the mitotic Golgi. Furthermore, the fact that the extent of marker recovery was similar for matrix and non-matrix protei ...
Inorganic pyrophosphate is located primarily in the mitochondria of
Inorganic pyrophosphate is located primarily in the mitochondria of

... In previous work we have shown that small changes in light-scattering, induced by gluconeogenic hormones, valinomycin and A23187, correlate well with changes in the mitochondrial matrix volume of hepatocytes measured in situ or after rapid cell disruption (Quinlan et al., 1983; Halestrap et al., 198 ...
dependent endoderm cell fate specification - EvoDevo
dependent endoderm cell fate specification - EvoDevo

... enabled the remarkable diversification within this clade. The process of gastrulation involves two tightly coupled events during embryogenesis of most metazoans. Morphogenesis produces a distinct internal epithelial layer in the embryo, and this epithelium becomes segregated as an endoderm/endomesod ...
Susceptibility to plant disease: more than a failure of host immunity
Susceptibility to plant disease: more than a failure of host immunity

... Endoreduplication: modification of the cell cycle in which nuclear DNA undergoes replication without subsequent cell division that leads to formation of nuclei with increased ploidy level [107]. The resulting ploidy level is expressed as the amount of DNA compared to that of a haploid nucleus. For e ...
Verticillium Infection Triggers VASCULAR
Verticillium Infection Triggers VASCULAR

... stream, diseased plants use at least two different strategies. Hop plants tolerant to V. albo-atrum infection were reported to show “prolonged or renewed activity” of the secondary cambium, which resulted in newly formed xylem cells that were free of tyloses and fungal mycelium (Talboys, 1958). A di ...
Antibody Selection for Immobilizing Living Bacteria
Antibody Selection for Immobilizing Living Bacteria

... against bacterial surface antigens associated with Salmonella enterica Serovar Typhimurium. The targeted bacterial antigens were CFA/I fimbriae, flagella, lipopolysaccharides (LPS), and capsular F1 antigen. The best immobilization of S. Typhimurium was achieved with the antibody against CFA/I fimbri ...
Full-Text PDF
Full-Text PDF

... to the thymus and as they mature T cells express a clonally restricted T cell receptor (TCR) and develop into two major lineages referred to as TCRαβ+ and TCRγδ+ . The TCRαβ+ lineage represents the major population of T cells in the peripheral immune system comprising >90% of the total T cells. Thes ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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