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Intraflagellar transport molecules in ciliary and nonciliary cells of the
Intraflagellar transport molecules in ciliary and nonciliary cells of the

... which contains the presynaptic terminals of photoreceptor cells connected to the postsynaptic terminals of the dendritic processes in secondary retinal neurons, namely bipolar and horizontal cells (Fig. 1, D–F). In addition, IFT20 was expressed in the cells of the RPE and in the ganglion cell layer ...
4-1
4-1

... Allow large molecules like RNA to pass through the membrane into the cytoplasm Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Encontro de Jovens Investigadores de Biologia Computacional
Encontro de Jovens Investigadores de Biologia Computacional

... chemotherapy failures worldwide. Although P-glycoprotein (P-gp) is one of the main contributors for MDR, the biophysical aspects of drug efflux by P-gp still remain largely unknown. Following our characterization of three drug-binding sites within P-gp\'s internal drug-binding pocket (DBP), a series ...
Transverse Viscoelastic Extension in Nitella
Transverse Viscoelastic Extension in Nitella

... Growth rate (% initial length / 24 hours) inhibited only 17% (4). In this study it was shown that in sequential FIG. 5. K+ stimulation of longitudinal (A) and transverse (B) extension treatments with acid pH and Mg2+, neither treatment abolished as a function of the in vivo growth rate. The applied ...
Left–right asymmetry: cilia stir up new surprises in the node
Left–right asymmetry: cilia stir up new surprises in the node

... Figure 1. Left – right (L– R) asymmetry in man. (a) In the wild-type, also known as ‘situs solitus’, the heart, stomach and spleen are oriented to the left side, whereas the liver is present on the right side. (b) In KS patients with ‘situs inversus’, transposition of the visceral organs occurs in a ...
pdf, 456 Ko
pdf, 456 Ko

... In the present work, we have investigated the possible synergy between Krox-20 and Hoxa1. During hindbrain development, Krox-20, which encodes a zinc finger transcription factor (Chavrier et al., 1988, 1990), is successively activated in two transverse stripes that prefigure and subsequently coincid ...
PDF
PDF

... 2228 RESEARCH ARTICLE ...
C. elegans daf-6 Encodes a Patched-Related Protein
C. elegans daf-6 Encodes a Patched-Related Protein

... that these vacuoles contained matrix material. Consistent with this observation, EM cross-sections of daf6(e1377) animals revealed that amphid cilia resided within a sheath cell pocket containing material similar in electron density to matrix material (Figure 1O). These findings are also consistent ...
Cell behaviour and cleft palate in the mutant mouse
Cell behaviour and cleft palate in the mutant mouse

... day of development. In the case of the naso-frontal region we have found that increased cell adhesion between the cells in the mutant causes clumping similar to that found elsewhere in the embryo and this retards the tissue expansion which occurs in the normal embryo by secretion of extracellular ma ...
Staphylococcal phenomics: metabolomic and proteomic responses
Staphylococcal phenomics: metabolomic and proteomic responses

... responses can vary in different microbial systems. There are many parameters which can influence the temperature tolerance in the microbial systems [36]. For example, when the ambient temperature decreases, extended expression of the σB factor is required for microbial survival as it assists in main ...
Chapter 4
Chapter 4

... information is passed from one generation to the next ...
Why Belzer UW® Cold Storage Solution?
Why Belzer UW® Cold Storage Solution?

... and prevent oedema. … UW pioneered the use of lactobionate and raffinose…Lactobionate remains the impermeant choice of having been successfully used in preservation solutions other than UW, being critical to the success of UW, and for its proposed iron chelation properties (cf. oygen-free radicals). ...
pptx
pptx

... Little is known about how metformin regulates GLUT transporters, although some evidence shows that metformin promotes their translocation to the AP membrane5. Under normal physiology, GLUT2 is known to translocate to the apical membrane of intestinal epithelia in response to a meal6. A previous stud ...
Photosynthesis Research
Photosynthesis Research

... Gunning. CLSM observations were made of chloroplasts in leaf cells that had first been determined by phase or bright field microscopy to be in the living condition, as evidenced by vigorous cytoplasmic streaming. These observations confirmed the widespread occurrence of strings of grana in all the spec ...
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pdf View

... and control the expression of more than one gene within the network. This depends on the complexes the gene products form with other RD proteins or co-activators/co-repressors. The RDN genes are expressed in different phases during the patterning of the retina and each of them exhibits a distinct sp ...
Secured cutting: controlling separase at the metaphase to anaphase
Secured cutting: controlling separase at the metaphase to anaphase

... separation in the second (Buonomo et al., 2000). Cohesin cleavage is therefore a universal mechanism for triggering anaphase. It is an irreversible step; once executed, chromosome segregation cannot be reversed. This suggests that cohesin cleavage must be tightly controlled, by mechanisms responding ...
Abstract Panax ginseng Meyer, belonging to the genus Panax of the
Abstract Panax ginseng Meyer, belonging to the genus Panax of the

... the surface of macrophages, can bind to the infectious organisms which expose mannose-containing glycans on their surface, enabling them to ingest and kill the foreign organisms [49]. In addition, animal lectins are involved in cell trafficking, immune regulation, and prevention of autoimmunity [44] ...
Chloroplasts in living cells and the string-of
Chloroplasts in living cells and the string-of

... Gunning. CLSM observations were made of chloroplasts in leaf cells that had first been determined by phase or bright field microscopy to be in the living condition, as evidenced by vigorous cytoplasmic streaming. These observations confirmed the widespread occurrence of strings of grana in all the s ...
Expression α Importance for the Up-Regulation of TNF- MOPC
Expression α Importance for the Up-Regulation of TNF- MOPC

... Thus, L-PAM treatment leads to up-regulated IFN-␤ expression not only at the mRNA level but also at the protein level. Assessment of the importance of IFN-␤ for L-PAM-induced upregulation of TNF-␣ expression in MOPC-315 tumor cells Experiments were conducted to determine whether IFN-␤ is important f ...
Structure/Function Analysis of ras Using Random Mutagenesis
Structure/Function Analysis of ras Using Random Mutagenesis

... localization and cell transformation (19,20). ras proteins bind GDP and GTP with high affinities (21-23) and display a low level of GTPase activity (24-27). In addition, the viral rasH and rasK p21s possess a GTPdependent autokinase activity that phosphorylates threonine-59 both in vitro and in vivo ...
Expression of Efflux Transporters in Human Ocular Tissues
Expression of Efflux Transporters in Human Ocular Tissues

... significantly influence ocular drug efficacy by means of absorption, distribution, and elimination (Dey et al., 2004; Hariharan et al., 2009). However, knowledge about these efflux transporters in ocular tissues is very limited, despite the potentially important role they may play in ocular drug dis ...
STUDENTS` MISCONCEPTIONS ABOUT CELL BIOLOGY AND
STUDENTS` MISCONCEPTIONS ABOUT CELL BIOLOGY AND

... involved in the study. Generalization of the findings to all students in Gode Zone must be considered with caution due to the nature of environment and the limited size of the sample. Students may not understand or may misinterpret the questions and options in the cell biology and cell division diag ...
Provisional PDF - BioMed Central
Provisional PDF - BioMed Central

... fonts indicate closely related upstream or downstream proteins. Blue or red indicate successfully validated gain of function and elevation of expression or loss of function and reduction of expression, respectively. Success of the validation by semi-quantitative RT-PCR was determined by an Fc value ...
Early Embryogenesis in Flowering Plants: Setting Up the Basic Body
Early Embryogenesis in Flowering Plants: Setting Up the Basic Body

... Figure 1 Early embryogenesis in Arabidopsis thaliana. Panels show longitudinal sections of embryos during consecutive developmental stages: (a) zygote, (b) elongated zygote, (c) one-cell stage, (d ) two- or four-cell stage, (e) octant stage, ( f ) dermatogen stage, ( g) early-globular stage, (h) mid ...
Quantitative phase microscopy – a new tool for investigating
Quantitative phase microscopy – a new tool for investigating

... of cultures to assess the progression towards confluency over designated periods of time.20 It is important to appreciate that methodologies previously established for the measurement of cell growth in culture are either destructive or extremely laborious. These include cell size measurement with fl ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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