inactivation of the odontogenic ameloblast
... (Odam, originally termed as APin) (Moffatt et al., 2008), and SCPP-Proline/Glutamine (P/Q)-rich-1 (Scpppq1) (Kawasaki, 2009; Moffatt et al., 2014). The three proteins are expressed in maturation stage ameloblasts, and also by the gingival cells that form the junctional epithelium (JE) (Moffatt et al ...
... (Odam, originally termed as APin) (Moffatt et al., 2008), and SCPP-Proline/Glutamine (P/Q)-rich-1 (Scpppq1) (Kawasaki, 2009; Moffatt et al., 2014). The three proteins are expressed in maturation stage ameloblasts, and also by the gingival cells that form the junctional epithelium (JE) (Moffatt et al ...
Neisseria meningitidis: an overview of the carriage state
... defence and hence be selected to survive nasopharyngeal colonization. Carriage itself can be an immunizing process resulting in systemic protective antibody responses. Frequent nasopharyngeal colonization with related bacteria like Neisseria lactamica improves natural immunity to meningococci by the ...
... defence and hence be selected to survive nasopharyngeal colonization. Carriage itself can be an immunizing process resulting in systemic protective antibody responses. Frequent nasopharyngeal colonization with related bacteria like Neisseria lactamica improves natural immunity to meningococci by the ...
View/Open
... occur in small inversions where loops don’t form.) Figure 8.8 shows a crossover within a loop. The two nonsister chromatids not involved in a crossover in the loop will end up in normal gametes (carrying either the normal chromosome or the intact inverted chromosome). The products of the crossover, ...
... occur in small inversions where loops don’t form.) Figure 8.8 shows a crossover within a loop. The two nonsister chromatids not involved in a crossover in the loop will end up in normal gametes (carrying either the normal chromosome or the intact inverted chromosome). The products of the crossover, ...
Two Classes of sir3 Mutants Enhance the sir1
... a collection of mutants including those termed the sir3eso mutants to emphasize their distinct phenotypes described here. A genetic interaction between SIR1 and SIR3 had previously been noted, in that overexpression of SIR1 can suppress the mating defect associated with certain sir3 alleles (Stone e ...
... a collection of mutants including those termed the sir3eso mutants to emphasize their distinct phenotypes described here. A genetic interaction between SIR1 and SIR3 had previously been noted, in that overexpression of SIR1 can suppress the mating defect associated with certain sir3 alleles (Stone e ...
The genetics of Caenorhabditis elegans.
... mutations on nervous systems. I n principle, it should be possible to dissect the genetic specification of a nervous system in much the same way as was done for biosynthetic pathways in bacteria or for bacteriophage assembly. However, one surmises that genetical analysis alone would have provided on ...
... mutations on nervous systems. I n principle, it should be possible to dissect the genetic specification of a nervous system in much the same way as was done for biosynthetic pathways in bacteria or for bacteriophage assembly. However, one surmises that genetical analysis alone would have provided on ...
"RNA Interference in Caenorhabditis elegans".
... one might detect suppression or enhancement of phenotypes in mutant strains. In C. elegans, RNAi can be induced by delivering dsRNA by microinjection (see Basic Protocol 1 and Alternate Protocol 1), feeding (see Basic Protocols 2, 3, and 4 and Alternate Protocol 2), or soaking (see Basic Protocol 5) ...
... one might detect suppression or enhancement of phenotypes in mutant strains. In C. elegans, RNAi can be induced by delivering dsRNA by microinjection (see Basic Protocol 1 and Alternate Protocol 1), feeding (see Basic Protocols 2, 3, and 4 and Alternate Protocol 2), or soaking (see Basic Protocol 5) ...
Identity elements in tRNA-mediated transcription
... Te, lines indicate partial repeats of the same sequence that are complementary to the tRNA T-loop ; D, line indicates sequence complementary to the D-arm of tRNATrp as presented in Fig. 4(a) ; Dh and Dd, short lines indicate sequences complementary to the tRNA D-loop. ...
... Te, lines indicate partial repeats of the same sequence that are complementary to the tRNA T-loop ; D, line indicates sequence complementary to the D-arm of tRNATrp as presented in Fig. 4(a) ; Dh and Dd, short lines indicate sequences complementary to the tRNA D-loop. ...
Consulta: subjectFacets:"16S rRNA" Registros recuperados: 43
... A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method was based on amplification of 552 nucleotide bases long sequence of 16S rRNA, targeted by Borrelia specific primers. In the present study, total RNA extracted from Ixodes ...
... A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method was based on amplification of 552 nucleotide bases long sequence of 16S rRNA, targeted by Borrelia specific primers. In the present study, total RNA extracted from Ixodes ...
Running Header: WHAT ARE THE GENETICS BEHIND DYSLEXIA
... families of developmental dyslexia” (Marino et al., 2010, p. 67). DCDC2 has evolving evidence that strongly suggests that it is in some way associated with dyslexia. DYX1C1 DYX1C1 is also considered a candidate gene for dyslexia (Svensson et al., 2010). One of its earliest appearances was in 1983 in ...
... families of developmental dyslexia” (Marino et al., 2010, p. 67). DCDC2 has evolving evidence that strongly suggests that it is in some way associated with dyslexia. DYX1C1 DYX1C1 is also considered a candidate gene for dyslexia (Svensson et al., 2010). One of its earliest appearances was in 1983 in ...
Tetraploid rescue - Development
... embryos were either extremely small or had a distinct extraembryonic region. Thus, it may be concluded that DsXM embryos can be identified under a stereomicroscope with considerable accuracy except for a small number of day 6 embryos. Histological characters of DsXM embryos on day 6 to 8 of pregnanc ...
... embryos were either extremely small or had a distinct extraembryonic region. Thus, it may be concluded that DsXM embryos can be identified under a stereomicroscope with considerable accuracy except for a small number of day 6 embryos. Histological characters of DsXM embryos on day 6 to 8 of pregnanc ...
Induced Adrenocortical Tumorigenesis in Mice
... adrenal glands of ovariectomized B6AF1 mice contained type A cells that expressed GATA4 antigen (Supplemental Fig. 2C) and type B cells that expressed both GATA4 (Supplemental Fig. 2C) and gremlin (Supplemental Fig. 2E). As in B6D2F1 mice, Gata4 haploinsufficiency mitigated ovariectomy-induced adren ...
... adrenal glands of ovariectomized B6AF1 mice contained type A cells that expressed GATA4 antigen (Supplemental Fig. 2C) and type B cells that expressed both GATA4 (Supplemental Fig. 2C) and gremlin (Supplemental Fig. 2E). As in B6D2F1 mice, Gata4 haploinsufficiency mitigated ovariectomy-induced adren ...
Quantitative trait loci affecting amylose, amylopectin and starch
... (AP) a branched molecule of very high molecular mass (5·106) and phytoglycogen a highly branched and soluble polymer. The AM:AP ratio is rather constant and close to 20/80, in the wild type but it may be strongly affected by mutations. Amylose-free kernels are produced by the waxy mutation. Converse ...
... (AP) a branched molecule of very high molecular mass (5·106) and phytoglycogen a highly branched and soluble polymer. The AM:AP ratio is rather constant and close to 20/80, in the wild type but it may be strongly affected by mutations. Amylose-free kernels are produced by the waxy mutation. Converse ...
Mouse Lefty2 and Zebrafish Antivin Are Feedback
... block Nodal signaling in a negative feedback mechanism, allowing tight control of Nodal signaling during vertebrate gastrulation. Results lefty2 Null Mutants Are Early Embryonic Lethal The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on ...
... block Nodal signaling in a negative feedback mechanism, allowing tight control of Nodal signaling during vertebrate gastrulation. Results lefty2 Null Mutants Are Early Embryonic Lethal The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on ...
TaqMan-Based Real-Time PCR for Genotyping Common
... and HP2 for typing (14, 15 ). More recently, a singlechain antibody-based ELISA test was also established (16 ). In addition, several HP-genotyping methods based on conventional PCR have been developed; however, these PCR-based methods need to amplify a relatively large DNA fragment to detect the 1. ...
... and HP2 for typing (14, 15 ). More recently, a singlechain antibody-based ELISA test was also established (16 ). In addition, several HP-genotyping methods based on conventional PCR have been developed; however, these PCR-based methods need to amplify a relatively large DNA fragment to detect the 1. ...
34386 - PubAg
... enzyme assays (14) as described by Frey et al. (10). Volicitin Incubations. Maize seedlings were cut off above the root and placed in shell vials containing 500 l of 50 mM sodium phosphate buffer adjusted to pH 8; seedlings were treated with buffer alone or with buffer containing 300 pmol synthetic ...
... enzyme assays (14) as described by Frey et al. (10). Volicitin Incubations. Maize seedlings were cut off above the root and placed in shell vials containing 500 l of 50 mM sodium phosphate buffer adjusted to pH 8; seedlings were treated with buffer alone or with buffer containing 300 pmol synthetic ...
Novel mutants of 23S RNA: characterization of
... importance of nucleotides within this region for cell viability and antibiotic resistance has been shown by site-directed mutagenesis (9-10). Protection of A2438, A2451 and A2602 are shown to be dependent on acyl moiety, U25O6, U2584, U2585 on the 3' terminal A and G2505 is protected by tRNA, lackin ...
... importance of nucleotides within this region for cell viability and antibiotic resistance has been shown by site-directed mutagenesis (9-10). Protection of A2438, A2451 and A2602 are shown to be dependent on acyl moiety, U25O6, U2584, U2585 on the 3' terminal A and G2505 is protected by tRNA, lackin ...
Package `biomartr`
... To automate the retrieval process on a meta-genomic scale, this package provides useful interface functions for genomic sequence retrieval and functional annotation retrieval. The major aim of biomartr is to facilitate computational reproducibility and large-scale handling of genomic data for (meta- ...
... To automate the retrieval process on a meta-genomic scale, this package provides useful interface functions for genomic sequence retrieval and functional annotation retrieval. The major aim of biomartr is to facilitate computational reproducibility and large-scale handling of genomic data for (meta- ...
Mar22_24
... of two logarithms, any base logarithms will give the same numerical result. i.e. We can use either the log10 or ln button on our calculator or even log2 if we care to do this. Extra Credit Project: Use a spreadsheet or write a computer program to generate the graphs that were shown two slides previo ...
... of two logarithms, any base logarithms will give the same numerical result. i.e. We can use either the log10 or ln button on our calculator or even log2 if we care to do this. Extra Credit Project: Use a spreadsheet or write a computer program to generate the graphs that were shown two slides previo ...
Quantitative Trait Analysis in Plants
... o Strength of the Q2 is greater than the strength of Q1 • But the two QTL have equal strength o Closer linkage leads to a perceived greater strength This is the confounding effect: there is a relationship between the marker/QTL linkage distance and the mean phenotypic expression level within each ma ...
... o Strength of the Q2 is greater than the strength of Q1 • But the two QTL have equal strength o Closer linkage leads to a perceived greater strength This is the confounding effect: there is a relationship between the marker/QTL linkage distance and the mean phenotypic expression level within each ma ...
Functional features of RUNX1 mutants in acute
... disorder of the hematopoietic stem cells that typically progresses from a relatively benign chronic phase (CP), which is characterized by massive accumulation of mature granulocytes, to an accelerated phase (AP), and ultimately into terminal blast crisis (BC), which resembles acute leukemia characte ...
... disorder of the hematopoietic stem cells that typically progresses from a relatively benign chronic phase (CP), which is characterized by massive accumulation of mature granulocytes, to an accelerated phase (AP), and ultimately into terminal blast crisis (BC), which resembles acute leukemia characte ...
Ret/PTC3 is the most frequent form of gene rearrangement
... papillary thyroid carcinomas only for ret/PTC1 rearrangements and found no rearrangement; Ishizaka et al. (1991) found one ret/PTC1 rearrangement among 11 carcinomas, and Wajjwalku et al. (1992) found only one such alteration among 38 carcinomas. On the basis of those observations, RET gene rearrang ...
... papillary thyroid carcinomas only for ret/PTC1 rearrangements and found no rearrangement; Ishizaka et al. (1991) found one ret/PTC1 rearrangement among 11 carcinomas, and Wajjwalku et al. (1992) found only one such alteration among 38 carcinomas. On the basis of those observations, RET gene rearrang ...
Selecting Degenerate Multiplex PCR Primers
... small. Furthermore, MIPS outperforms an existing algorithm which was designed for a related degenerate primer selection problem. An implementation of the MIPS algorithm is available for research purposes from the website http://www.cse.wustl.edu/ zhang/software/mips. ...
... small. Furthermore, MIPS outperforms an existing algorithm which was designed for a related degenerate primer selection problem. An implementation of the MIPS algorithm is available for research purposes from the website http://www.cse.wustl.edu/ zhang/software/mips. ...
HETEROSIS IN THE PERFORMANCE OF MICE
... with larger animals, since mice, like cattle, sheep and swine are lactating mammals in which the direct maternal influence on survival and early development is highly important. Of course, the applicability of results with mice in work with other species is limited by the similarity in the genetic b ...
... with larger animals, since mice, like cattle, sheep and swine are lactating mammals in which the direct maternal influence on survival and early development is highly important. Of course, the applicability of results with mice in work with other species is limited by the similarity in the genetic b ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse