Resveratrol Opportunism: What Is the Science Behind the Claims?
... one form is preferable to the other in terms of potential health benefits. It is well known that many genes are influenced positively in vitro by both resveratrol and methylated resveratrol; therefore, it is premature to conclude that one form is more beneficial than the other.13 It is likely that r ...
... one form is preferable to the other in terms of potential health benefits. It is well known that many genes are influenced positively in vitro by both resveratrol and methylated resveratrol; therefore, it is premature to conclude that one form is more beneficial than the other.13 It is likely that r ...
Abstracts - Parthenon Management Group
... changes. Another central HPA axis gene, FKBP5, whose product is a regulator of glucocorticoid receptor activity, has been shown to be up-regulated by glucocorticoid exposure in mice through a decrease in DNA methylation. Recent work aims to further dissect these relationships by distinguishing betwe ...
... changes. Another central HPA axis gene, FKBP5, whose product is a regulator of glucocorticoid receptor activity, has been shown to be up-regulated by glucocorticoid exposure in mice through a decrease in DNA methylation. Recent work aims to further dissect these relationships by distinguishing betwe ...
Genetics of the shaded American Shorthair
... and chinchilla patterns are grouped together as shaded cats in this paper, since the difference between the shaded and chinchilla cats varies only in one pattern attribute, the width of the white undercoat. Evidence of a pattern or barring on the legs, neck, and tail or, worse, on the body is effec ...
... and chinchilla patterns are grouped together as shaded cats in this paper, since the difference between the shaded and chinchilla cats varies only in one pattern attribute, the width of the white undercoat. Evidence of a pattern or barring on the legs, neck, and tail or, worse, on the body is effec ...
Genetics of the shaded American Shorthair
... orange gene) than it does on black pigment in all breeds. Because of this complexity, this paper deals predominantly with black pigmented (shaded silver) cats. The effect of the silver gene in combination with the red can be exaggerated. To Stripe or Not to Stripe - the major unpatterned tabby gene ...
... orange gene) than it does on black pigment in all breeds. Because of this complexity, this paper deals predominantly with black pigmented (shaded silver) cats. The effect of the silver gene in combination with the red can be exaggerated. To Stripe or Not to Stripe - the major unpatterned tabby gene ...
Real-time PCR Handbook
... sensitivity. However, the y-intercept value may be useful for comparing different amplification systems and targets. ...
... sensitivity. However, the y-intercept value may be useful for comparing different amplification systems and targets. ...
Cormack et al, 1991 Cell
... Regions of the Yeast TFIID Core Domain That Rescue an Otherwise Human TFIID The experiments described in Figure 3 define regions of yeast TFIID core that cannot be replaced by the homologous region of human TFIID to generate a fully functional protein. To determine if the same regions of yeast TFIID ...
... Regions of the Yeast TFIID Core Domain That Rescue an Otherwise Human TFIID The experiments described in Figure 3 define regions of yeast TFIID core that cannot be replaced by the homologous region of human TFIID to generate a fully functional protein. To determine if the same regions of yeast TFIID ...
MATRILINEAL, a sperm-specific phospholipase, triggers maize
... tube guidance, sperm capacitation, and fertilization12–15,28, while others are annotated as being involved in endomembrane transport and signalling (Table 2 and Extended Data Table 6). Given the intensive communication between the two gametophytes and the dynamic membrane reshuffling involved in fer ...
... tube guidance, sperm capacitation, and fertilization12–15,28, while others are annotated as being involved in endomembrane transport and signalling (Table 2 and Extended Data Table 6). Given the intensive communication between the two gametophytes and the dynamic membrane reshuffling involved in fer ...
Influence of the PsbA1/PsbA3, Ca2+/Sr2+ and Cl−/Br
... donor side [17,18]. The Ca 2+/Sr 2+ exchange has also been shown to decrease the entropic component in the formation of the transition state in the S3YZ • to S0YZ transition [19]. However, it was demonstrated by flash induced fluorescence decay measurements that the Ca2+/Sr 2+ exchange might also dece ...
... donor side [17,18]. The Ca 2+/Sr 2+ exchange has also been shown to decrease the entropic component in the formation of the transition state in the S3YZ • to S0YZ transition [19]. However, it was demonstrated by flash induced fluorescence decay measurements that the Ca2+/Sr 2+ exchange might also dece ...
jing is required for wing development and to establish the
... Like most transcription factors, those that are required for PD axis formation in the Drosophila leg have additional and very distinct functions at other stages and tissues during development. For example, dac plays an important role in the development of the eye, central nervous system (CNS), and t ...
... Like most transcription factors, those that are required for PD axis formation in the Drosophila leg have additional and very distinct functions at other stages and tissues during development. For example, dac plays an important role in the development of the eye, central nervous system (CNS), and t ...
Polyploidy
... • Understand the differences between ‘Interference’, and the suppression of recombination resulting from inversions, • Be able to recognize data, and predict results given either case. ...
... • Understand the differences between ‘Interference’, and the suppression of recombination resulting from inversions, • Be able to recognize data, and predict results given either case. ...
Review of the p53 Tumor Suppressor Gene and its Role in Gliomas
... Uncontrolled growth is required for all cancer development, while these other qualities apply to specific ones. ...
... Uncontrolled growth is required for all cancer development, while these other qualities apply to specific ones. ...
Differential Enzyme Targeting As an Evolutionary Adaptation to
... 1996; Danpure 1997). In many species in which AGT is entirely peroxisomal (e.g., human, rabbit, and guinea pig) translation start site 1 has been lost during evolution (Takada et al. 1990; Purdue, Lumb, and Danpure 1992; Birdsey and Danpure 1998), whereas AGT in the cat is almost entirely mitochondr ...
... 1996; Danpure 1997). In many species in which AGT is entirely peroxisomal (e.g., human, rabbit, and guinea pig) translation start site 1 has been lost during evolution (Takada et al. 1990; Purdue, Lumb, and Danpure 1992; Birdsey and Danpure 1998), whereas AGT in the cat is almost entirely mitochondr ...
Anaerobic Growth of Escherichia coli K12 with
... blocked in the cyclization of this intermediate (see scheme above). More recently, menaquinone mutants were found amongst mutants selected for their inability to use fumarate as a terminal electron acceptor for anaerobic growth (Lambden & Guest, 1976). Studies with two mutants showed that normal ana ...
... blocked in the cyclization of this intermediate (see scheme above). More recently, menaquinone mutants were found amongst mutants selected for their inability to use fumarate as a terminal electron acceptor for anaerobic growth (Lambden & Guest, 1976). Studies with two mutants showed that normal ana ...
Sample
... D) genetic engineering Answer: B Page Ref: 54 Box: SOCIAL ISSUES: HEALTH: The Pros and Cons of Reproductive Technologies Skill: Remember Objective: 2.4 56) Children conceived through in vitro fertilization A) may be genetically unrelated to both of their parents. B) tend to develop insecure attachme ...
... D) genetic engineering Answer: B Page Ref: 54 Box: SOCIAL ISSUES: HEALTH: The Pros and Cons of Reproductive Technologies Skill: Remember Objective: 2.4 56) Children conceived through in vitro fertilization A) may be genetically unrelated to both of their parents. B) tend to develop insecure attachme ...
Pharmacogenetics of warfarin: current status and future
... vitamin K, illness, age, gender, concurrent medication and body surface area, and by genetic variation.1–8 To be able to improve the benefit–harm profile associated with warfarin therapy, all these factors need to be taken into account. There is increasing interest in whether pharmacogenetics can ac ...
... vitamin K, illness, age, gender, concurrent medication and body surface area, and by genetic variation.1–8 To be able to improve the benefit–harm profile associated with warfarin therapy, all these factors need to be taken into account. There is increasing interest in whether pharmacogenetics can ac ...
Variation and Selection at the CAULIFLOWER Floral Homeotic
... which 35 are nucleotide polymorphisms and 52 are from insertion/deletion (indel) changes of 1–12 bp in length. All of the indels are in introns. Of the 35 nucleotide polymorphisms found in BoCAL, 25 are located within introns while 10 are in coding regions. The coding region polymorphisms include 7 ...
... which 35 are nucleotide polymorphisms and 52 are from insertion/deletion (indel) changes of 1–12 bp in length. All of the indels are in introns. Of the 35 nucleotide polymorphisms found in BoCAL, 25 are located within introns while 10 are in coding regions. The coding region polymorphisms include 7 ...
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... E. siliculosus sporophytes can be produced in a number of different ways (Fig. 1): (1) via gamete fusion and zygote production; (2) by mito-spores produced by the plurilocular sporangia of sporophytes; (3) from a minority of the meio-spores produced by unilocular sporangia (the majority producing ga ...
... E. siliculosus sporophytes can be produced in a number of different ways (Fig. 1): (1) via gamete fusion and zygote production; (2) by mito-spores produced by the plurilocular sporangia of sporophytes; (3) from a minority of the meio-spores produced by unilocular sporangia (the majority producing ga ...
CCA Summer 2004 Newsletter - Children`s Craniofacial Association
... “dominates” over the unchanged gene, causing the features of CCD. The gene that causes CCD is denoted by the symbol RUNX2, and it directs the body to make a protein that helps to control the development of osteoblasts, which are cells that are important in the formation of bone. Gene testing is avai ...
... “dominates” over the unchanged gene, causing the features of CCD. The gene that causes CCD is denoted by the symbol RUNX2, and it directs the body to make a protein that helps to control the development of osteoblasts, which are cells that are important in the formation of bone. Gene testing is avai ...
IVRI OB 1809
... which differed in one recognisable respect: one was tall, the oth<;r dwarf. The first generation, or F I , progeny were all ~tall, but when they were self-pollinated they produced second generation, or F 2 , progeny three-quarters of which were tall and one-quarter dwarf. The dwarfall bred true, and ...
... which differed in one recognisable respect: one was tall, the oth<;r dwarf. The first generation, or F I , progeny were all ~tall, but when they were self-pollinated they produced second generation, or F 2 , progeny three-quarters of which were tall and one-quarter dwarf. The dwarfall bred true, and ...
A glucagon-like endocrine pathway in Drosophila modulates both
... start sites. The Akhrrev flies contain only a 17 bp remnant (catgttatttcatcatg) at the original P-element (EY11371) insertion site and an otherwise wild-type gene scaffold. The Akhrnull flies contain an ~450 bp remnant of the excised P element fused to genomic sequence 144 bp downstream of the origi ...
... start sites. The Akhrrev flies contain only a 17 bp remnant (catgttatttcatcatg) at the original P-element (EY11371) insertion site and an otherwise wild-type gene scaffold. The Akhrnull flies contain an ~450 bp remnant of the excised P element fused to genomic sequence 144 bp downstream of the origi ...
A glucagon-like endocrine pathway in Drosophila
... synthesis and breakdown of glycogen have clear homology to those found in mammals (Orgad et al., 1987). Thus, the study of fly mutants with alterations in lipid accumulation in the fat body raises the intriguing possibility that they will provide insight into genetic determinants of human obesity an ...
... synthesis and breakdown of glycogen have clear homology to those found in mammals (Orgad et al., 1987). Thus, the study of fly mutants with alterations in lipid accumulation in the fat body raises the intriguing possibility that they will provide insight into genetic determinants of human obesity an ...
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... is covered by a cuticle, an extracellular matrix secreted by ectodermal cells that forms the distal interface with the environment. It has been shown that Hydra cuticle proteins from the PPOD and SWT families are associated with chondroitin and chondroitin 6-sulfate (Bottger et al., 2012). The behav ...
... is covered by a cuticle, an extracellular matrix secreted by ectodermal cells that forms the distal interface with the environment. It has been shown that Hydra cuticle proteins from the PPOD and SWT families are associated with chondroitin and chondroitin 6-sulfate (Bottger et al., 2012). The behav ...
International Agency for Research on Cancer (IARC)
... imported feed found an excess of hepatocellular carcinoma among those who had had major exposure to aflatoxin-contaminated feed in the period 10 or more years before diagnosis. In a cohort study in China, a significant elevation in risk for hepatocellular carcinoma was found among people with aflato ...
... imported feed found an excess of hepatocellular carcinoma among those who had had major exposure to aflatoxin-contaminated feed in the period 10 or more years before diagnosis. In a cohort study in China, a significant elevation in risk for hepatocellular carcinoma was found among people with aflato ...
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... identity with Drosophila BR-C Z1, Z2, Z3 and Z4, respectively). Moreover, the order in which the exons encoding the zinc finger domains follow within the genomic DNA (i.e. Z1, Z4, Z2 and Z3; Fig. 1A) is conserved among Tribolium, Drosophila and Bombyx (DiBello et al., 1991; Bayer et al., 1996a; Ijir ...
... identity with Drosophila BR-C Z1, Z2, Z3 and Z4, respectively). Moreover, the order in which the exons encoding the zinc finger domains follow within the genomic DNA (i.e. Z1, Z4, Z2 and Z3; Fig. 1A) is conserved among Tribolium, Drosophila and Bombyx (DiBello et al., 1991; Bayer et al., 1996a; Ijir ...
Molecular basis of the clinical variability of Rett syndrome
... The manuscript submitted by Elisa Scala for defending her Ph.D. in Medical Genetics is dealing with Rett Syndrome, a severe neurodevelopmental disorder that mostly affects females and that is characterised by a wide spectrum of clinical manifestations. The manuscript focuses on the molecular bases t ...
... The manuscript submitted by Elisa Scala for defending her Ph.D. in Medical Genetics is dealing with Rett Syndrome, a severe neurodevelopmental disorder that mostly affects females and that is characterised by a wide spectrum of clinical manifestations. The manuscript focuses on the molecular bases t ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse