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Bicoid associates with the 5 -cap-bound complex of caudal mRNA
Bicoid associates with the 5 -cap-bound complex of caudal mRNA

... Translational control plays a key role in many biological processes including pattern formation during early Drosophila embryogenesis. In this process, the anterior determinant Bicoid (BCD) acts not only as a transcriptional activator of segmentation genes but also causes specific translational repr ...
IMPROVE SMALL RNA-MEDIATED GENE SILENCING
IMPROVE SMALL RNA-MEDIATED GENE SILENCING

... siRNAs and natural antisense transcript siRNAs (NAT-siRNAs) (Axtell 2013; Ghildiyal and Zamore 2009). Common features of all small RNAs are that members of the DCL family are recruited to process long dsRNAs into ~20-30 nucleotides, and one strand of the resulting small RNA duplexes are thereafter i ...
Creative Activities in Music – A Genome
Creative Activities in Music – A Genome

... Creative activities in music represent cognitive functions of the human brain. A creative performance can be defined as a production of work or performance that is both original and appropriate for the situation in which it occurs [1–3]. Creativity requires the presence of several traits including i ...
M.Sc., Biotechnology - Alagappa University
M.Sc., Biotechnology - Alagappa University

... Biochemistry is the science that deals with the study of various biomolecules that occur in living cells and organisms and also with the metabolic and chemical reactions occurring within them. It is also concerned with the entire range of life forms beginning from the obligate intracellular parasite ...
cloning of gs1 gene encodes glutamine synthetase 1 and
cloning of gs1 gene encodes glutamine synthetase 1 and

... Biotechnology and Seedling tobacco with mutated GS genes driven by tapetum and microspore – specific promoters. Consequently, the plants were male sterile, but this could be reversed by spraying with glutamine. This result demonstrated the importance of GS1 in anthers and pollen. There is also evid ...
Chapter 4 Extension Activity
Chapter 4 Extension Activity

... In animals with two eyes, each is positioned to the left and right of the centre of the head and as a result, the image of a scene that falls on each of the two eyes is slightly different. In animals that have forward-directing eyes, there is an overlap in the field of vision of the two eyes. The ab ...
Phox2b and Midkine/Alk signaling in the control of sympathetic
Phox2b and Midkine/Alk signaling in the control of sympathetic

The Mycobacterium tuberculosis katG promoter region contains a
The Mycobacterium tuberculosis katG promoter region contains a

... with these show similarity to previously identified mycobacterial promoters. Deletions in the promoter fragment, introduced with BAL-31 nuclease and restriction endonucleases, revealed that a region between 559 and 448 bp upstream of the translation initiation codon, designated the upstream activato ...
A novel locus of Yersinia enterocolitica serotype O:3 involved in
A novel locus of Yersinia enterocolitica serotype O:3 involved in

... was unable to trans-complement the mutation in YeO3RfbR12. In conclusion, these experiments clearly demonstrate that structural requirements of phage ~R1-37 receptor are determined by the trs locus and that the locus is an operon longer than 8 kb in size. Strangely, YeO3-RfbR14R/pRV17 was resistant, ...
Handout - 6 - CM - Outline Genomic Model for HL7 V2
Handout - 6 - CM - Outline Genomic Model for HL7 V2

... Document1- McDonald CJ mutations data base carries records that include a Mutation and a specimen ID as well as mutation (HGVS) the organ, histology and other specifics for each submission. It stores simple mutations and structural mutations in different tables. And carries many records for each di ...
mgm1, the earliest sex-specific germline marker in Drosophila
mgm1, the earliest sex-specific germline marker in Drosophila

... male germ cells. In fact, males carrying this particular mutation are initially fertile, but they become sterile after a few days (Hime and Fuller, manuscript in preparation; cited in Kiger et al., 2000). We now wondered whether maintenance of male germ cells requires esg expression in somatic gonad ...
XIST
XIST

... RNA polymerase in the antisense orientation. As RNA polymerase proceeds along the Tsix DNA, the ‘melting’ of the complementary DNA strands and the presence of the large polymerase complex along the template may serve as an obstacle for the transcription of Xist in the opposite direction. (C) Sites a ...
marker assisted selection in disease resistance breeding
marker assisted selection in disease resistance breeding

... acceptable and that the pathogen reproduces by sexual means. Also, multilines may not hold a necessary uniformity that many cropping systems require, which make them not feasible to practical utility. The second option for durable resistance is gene pyramiding. In theory, pyramiding several “undefea ...
Marker-Assisted Selection for Disease Resistance in Wheat and
Marker-Assisted Selection for Disease Resistance in Wheat and

... selection because they are expensive or time-consuming to measure, have low penetrance or complex inheritance; (ii) traits whose selection depends on specific environments or host developmental stages; (iii) maintenance of recessive alleles during backcrossing or for speeding up backcross breeding i ...
Finding New Clock Components: Past and Future
Finding New Clock Components: Past and Future

... mutations that alter period length by more than 15% (3-4 h) or lead to a complete loss of circadian rhythms. When multiple alleles are available, period-shortening and -lengthening mutations are observed, as well as loss-of-rhythm mutants. Ironically, per met all of these criteria from the beginning ...
Journal of Bacteriology
Journal of Bacteriology

... transposon had inserted in a dnaK homologue which is located downstream of grpE and upstream of dnaJ. Analysis of putisolvin production and expression studies indicate that dnaK, together with the dnaJ and grpE heat shock genes, takes part in the positive regulation (directly or indirectly) of putis ...
ch 11_4
ch 11_4

... Morgan and his associates observed so many genes that were inherited together that, before long, they could group all of the fly’s genes into four linkage groups. The linkage groups assorted independently, but all of the genes in one group were inherited together. As it turns out, Drosophila has fou ...
Meiosis I - scecinascience
Meiosis I - scecinascience

... Morgan and his associates observed so many genes that were inherited together that, before long, they could group all of the fly’s genes into four linkage groups. The linkage groups assorted independently, but all of the genes in one group were inherited together. As it turns out, Drosophila has fou ...
Campbell`s Biology: Concepts and Connections, 7e (Reece et al
Campbell`s Biology: Concepts and Connections, 7e (Reece et al

... usually cause the death of the embryo. C) Most individuals carrying a lethal dominant allele have the disorder and die before they reproduce, whereas individuals carrying a lethal recessive allele are more likely to be healthy and reproduce. D) The presence of a lethal dominant allele causes sterili ...
Sequence requirements for function of the
Sequence requirements for function of the

... machinery, amplification represents a dramatic example of how DNA replication can be regulated in response to the developmental program. The Drosophila oocyte is surrounded by a somatically derived epithelium called the follicle cells. The follicle cells lay down protective coverings around the oocy ...
Jigsaw handout - the Biology Scholars Program Wiki
Jigsaw handout - the Biology Scholars Program Wiki

... repressor. Lac repressor is a DNA binding protein that binds to a site on the DNA called the operator. The operator partially overlaps with the promoter, which is the site where RNA polymerase binds to initiate transcription. When lac repressor binds to the operator site, RNA polymerase cannot bind ...
Statistic and Analytical Strategies for HLA Data
Statistic and Analytical Strategies for HLA Data

... level “α”, i.e., specifying in advance the allowable probability (α) of false-positive errors in this test (generally, α=0.05); additionally, you should decide whether a one-sided test or twosided test will be used. The smaller α is, the larger the sample size must be. The test power should also be ...
characterizing the genetic bases of autosomal recessive disorders
characterizing the genetic bases of autosomal recessive disorders

... Autosomal recessive disorders have devastating effects on patients and their families. Elucidating the genetic bases of such disorders is essential to improve their clinical outcome and for implementing effective prevention programs. In this dissertation, the genetic bases of seven autosomal recessi ...
Foundations of Biology
Foundations of Biology

... The authors who reported the presence of mitochondrial genes in amitochondrial eukaryotes all reinterpreted prevailing theory in saying that mitochondria must have been present then lost after they had transferred some of their genetic information to the nucleus. The hydrogenosome, a structure invol ...
The Origin and Development of Neural Crest
The Origin and Development of Neural Crest

... After the neural crest cells leave the migration staging area, they migrate either ventrally or dorsal-laterally away from the neural tube (Fig. 1, no. 2). In mice, these migratory events appear to occur simultaneously, whereas, in chick, dorsal–lateral migration of melanoblasts appears to be delaye ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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