Growth medium composition-determined regulatory mechanisms
... muconolactone isomerase and catechol 1,2-dioxygenase, respectively (Houghton et al., 1995). The induction of this operon, which is σ&%-independent, requires a LysR family transcriptional activator, CatR, and an inducer molecule, cis,cis-muconate (CCM), an intermediate of the ortho-pathway (Rothmel e ...
... muconolactone isomerase and catechol 1,2-dioxygenase, respectively (Houghton et al., 1995). The induction of this operon, which is σ&%-independent, requires a LysR family transcriptional activator, CatR, and an inducer molecule, cis,cis-muconate (CCM), an intermediate of the ortho-pathway (Rothmel e ...
Probable presence of an ubiquitous cryptic mitochondrial gene on
... gene has been named gau for gene antisense ubiquitous in mtDNAs. The length of the deduced protein is approximately 100 amino acids. In vertebrates, several stop codons have been found in the mt gau region, and potentially functional gau regions have been found in nuclear genomes. However, a recent ...
... gene has been named gau for gene antisense ubiquitous in mtDNAs. The length of the deduced protein is approximately 100 amino acids. In vertebrates, several stop codons have been found in the mt gau region, and potentially functional gau regions have been found in nuclear genomes. However, a recent ...
Predicting tRNA and tmRNA genes Aragorn - SEA
... the discriminator base, and it is a critical part of the recognition system that the tRNA synthetase uses to charge the tRNA with the correct amino acid. The discriminator base is followed by the sequence CCA. The ends of the tRNA must be carefully checked. Use Aragorn (v 1.2.38 or later) to call th ...
... the discriminator base, and it is a critical part of the recognition system that the tRNA synthetase uses to charge the tRNA with the correct amino acid. The discriminator base is followed by the sequence CCA. The ends of the tRNA must be carefully checked. Use Aragorn (v 1.2.38 or later) to call th ...
The RNA world meets behavior: AfiI pre
... transcriptome remains unknown. Although we understand the chemical basis and are learning about both the mechanism and the preferred targets for this type of editing, an essential question remains: why do organisms recode mRNAs enzymatically rather than simply incorporating those changes into the ge ...
... transcriptome remains unknown. Although we understand the chemical basis and are learning about both the mechanism and the preferred targets for this type of editing, an essential question remains: why do organisms recode mRNAs enzymatically rather than simply incorporating those changes into the ge ...
PHYSIOLOGICAL ADAPTATION IN LABORATORY ENVIRONMENTS
... ability to cling to vertical surfaces, results in a rapid increase in heat tolerance in D. melanogaster (Huey et al. 1991). In a modification of the method, knockdown times for D. melanogaster at 39°C increased fourfold after eighteen generations of selection (McColl et al. 1996). Similarly, flight ...
... ability to cling to vertical surfaces, results in a rapid increase in heat tolerance in D. melanogaster (Huey et al. 1991). In a modification of the method, knockdown times for D. melanogaster at 39°C increased fourfold after eighteen generations of selection (McColl et al. 1996). Similarly, flight ...
Microbiology
... Experiments were designed to study the relationship between gacS, rpoS and mutS. These studies showed that (i) a functional gac system is required for the expression of rpoS, (ii) RpoS suppresses the expression of mutS and therefore increases the frequency of gac mutants, and (iii) upon mutation of ...
... Experiments were designed to study the relationship between gacS, rpoS and mutS. These studies showed that (i) a functional gac system is required for the expression of rpoS, (ii) RpoS suppresses the expression of mutS and therefore increases the frequency of gac mutants, and (iii) upon mutation of ...
SPT3 interacts with TFIID to allow normal transcription in
... spt3 sup alleles were used: one strong allele, spt3-401, and three weak alleles, spt3-417, spt3-426, and spt3-445. For each case examined, the spt3 ~up m u t a t i o n s suppressed the transcriptional defects caused by sptl5-21 (Fig. 2). For his4-9176, previous work demonstrated that sptl 521 suppre ...
... spt3 sup alleles were used: one strong allele, spt3-401, and three weak alleles, spt3-417, spt3-426, and spt3-445. For each case examined, the spt3 ~up m u t a t i o n s suppressed the transcriptional defects caused by sptl5-21 (Fig. 2). For his4-9176, previous work demonstrated that sptl 521 suppre ...
Inhibition of Wound-Induced Accumulation of
... expression can be prevented by SA or aspirin (Doherty et al., 1988; Peña-Cortés et al., 1993; Doares et al., 1995). Previous results have shown that SA or aspirin inhibit the conversion of 13-HPLA to 12-oxo-PDA, thereby inhibiting the signal pathway by blocking the synthesis of JA (PeñaCortés et ...
... expression can be prevented by SA or aspirin (Doherty et al., 1988; Peña-Cortés et al., 1993; Doares et al., 1995). Previous results have shown that SA or aspirin inhibit the conversion of 13-HPLA to 12-oxo-PDA, thereby inhibiting the signal pathway by blocking the synthesis of JA (PeñaCortés et ...
Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter
... Effect of CLA on Scd gene transcription Previous studies have shown that supplemental feeding of CLA to dairy cows can have effects on the desaturase ratio. For this reason we were interested in the effect that CLA would have on activation of the bovine Scd gene promoter. Mac-T cells were transfected w ...
... Effect of CLA on Scd gene transcription Previous studies have shown that supplemental feeding of CLA to dairy cows can have effects on the desaturase ratio. For this reason we were interested in the effect that CLA would have on activation of the bovine Scd gene promoter. Mac-T cells were transfected w ...
Biomart/ GENOME ALIGNMENT III
... The comparison of the mouse and human genomes has demonstrated the power of comparative genomics in inferring the evolutionary history of species and in identifying functional regions in genomes. The possibilities for identifying regions under selection are enhanced with the addition of more sequenc ...
... The comparison of the mouse and human genomes has demonstrated the power of comparative genomics in inferring the evolutionary history of species and in identifying functional regions in genomes. The possibilities for identifying regions under selection are enhanced with the addition of more sequenc ...
Aggregate, composed, and evolved systems
... assumptions made about the structure of groups in models of group selection. The models started by focusing on genes and individual organisms but in the process made standard simplifying assumptions appropriate for some questions at those levels, but inappropriate for almost any questions about high ...
... assumptions made about the structure of groups in models of group selection. The models started by focusing on genes and individual organisms but in the process made standard simplifying assumptions appropriate for some questions at those levels, but inappropriate for almost any questions about high ...
C 2: A A -
... aeruginosa isolate in France (14) as well as the structurally related blaIBC-2 gene from a Greek isolate in Thessaloniki (33). These results suggested that these ESBL genes might have a wider scattered distribution than VEB and PER enzymes. One of the most interesting developments in research in ESB ...
... aeruginosa isolate in France (14) as well as the structurally related blaIBC-2 gene from a Greek isolate in Thessaloniki (33). These results suggested that these ESBL genes might have a wider scattered distribution than VEB and PER enzymes. One of the most interesting developments in research in ESB ...
Restless Legs Syndrome
... causative in 50% of RLS cases – this is a level unprecedented for a common disease. • The genetic contribution of BTBD9 to RLS approximates that of the ApoE4 allele association to Alzheimer’s disease. • The results are extremely credible – the gene variants and their effect sizes are similar in 5 di ...
... causative in 50% of RLS cases – this is a level unprecedented for a common disease. • The genetic contribution of BTBD9 to RLS approximates that of the ApoE4 allele association to Alzheimer’s disease. • The results are extremely credible – the gene variants and their effect sizes are similar in 5 di ...
Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in
... evolved clones isolated at several generations from one population. A total of 45 mutations were found in the clone sampled after 20,000 generations (Barrick et al. 2009), of which about one-quarter had been identified by the previous genetic studies. DNA supercoiling provides an interesting candida ...
... evolved clones isolated at several generations from one population. A total of 45 mutations were found in the clone sampled after 20,000 generations (Barrick et al. 2009), of which about one-quarter had been identified by the previous genetic studies. DNA supercoiling provides an interesting candida ...
X Chromosome Aneuploidy: A Look at the Effects of X Inactivation
... hemophilia, whereas a female without Turner Syndrome would need to have two copies of the recessive gene, which is much rarer. Most X0 females spontaneously abort in the womb, while the majority of known living Turner cases are mosaics (Frias, 2003). Mosaicism occurs when there are two or more cell ...
... hemophilia, whereas a female without Turner Syndrome would need to have two copies of the recessive gene, which is much rarer. Most X0 females spontaneously abort in the womb, while the majority of known living Turner cases are mosaics (Frias, 2003). Mosaicism occurs when there are two or more cell ...
chapt 10
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
chicken.db - Bioconductor
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
When the two levels of red and green are
... DNA is used to carry the instructions for cell processes. DNA is made up of four nucleotide bases: adenine, cytosine, guanine and thymine (abbreviated as A, C, G and T respectively). These bases join into two complementary pairs, with A only binding to T and C with G. The bases are arranged in a dou ...
... DNA is used to carry the instructions for cell processes. DNA is made up of four nucleotide bases: adenine, cytosine, guanine and thymine (abbreviated as A, C, G and T respectively). These bases join into two complementary pairs, with A only binding to T and C with G. The bases are arranged in a dou ...
MENDEL`S PRINCIPLES
... their passage from one generation to the next. Gregor Johann Mendel discovered these rules of inheritance; we derive and expand upon his rules in this chapter (fig. 2.1). In 1900, three botanists, Carl Correns of Germany, Erich von Tschermak of Austria, and Hugo de Vries of Holland, defined the rules ...
... their passage from one generation to the next. Gregor Johann Mendel discovered these rules of inheritance; we derive and expand upon his rules in this chapter (fig. 2.1). In 1900, three botanists, Carl Correns of Germany, Erich von Tschermak of Austria, and Hugo de Vries of Holland, defined the rules ...
Head induction in the chick - Max-Planck
... node/mesendoderm, the definitive cause of these defects remained unclear. Several other experiments have addressed the role of the visceral endoderm more directly. Chimeric mouse embryos composed predominantly of wild-type cells, but entirely of Nodal−/− or Otx2−/− cells in the visceral endoderm, di ...
... node/mesendoderm, the definitive cause of these defects remained unclear. Several other experiments have addressed the role of the visceral endoderm more directly. Chimeric mouse embryos composed predominantly of wild-type cells, but entirely of Nodal−/− or Otx2−/− cells in the visceral endoderm, di ...
Fingerprinting the Fungal Community
... used to discriminate not only between fungi and other kingdoms, but can be designed to differentiate between fungal groups and potentially to the species level. In practice, there may be overlap with sequences from other eukaryotic groups making it difficult to design primer sets specific to fungi ( ...
... used to discriminate not only between fungi and other kingdoms, but can be designed to differentiate between fungal groups and potentially to the species level. In practice, there may be overlap with sequences from other eukaryotic groups making it difficult to design primer sets specific to fungi ( ...
Full Text
... al., 1994; Yamada et al., 1991). Finally, a number of studies have implicated asymmetric sources of signals around Hensen’s node as the initial event leading to later L-R asymmetry of the viscera (reviewed (Harvey, 1998)). Recent research has identified molecular events upstream of the formation of ...
... al., 1994; Yamada et al., 1991). Finally, a number of studies have implicated asymmetric sources of signals around Hensen’s node as the initial event leading to later L-R asymmetry of the viscera (reviewed (Harvey, 1998)). Recent research has identified molecular events upstream of the formation of ...
HMG CoA reductase
... 2. Regulation of excess intracellular free cholesterol through the activity of acyl-CoA:cholesterol acyltransferase (ACAT) 3. Regulation of plasma cholesterol levels via LDL receptor-mediated uptake & HDL-mediated reverse transport (in liver). ...
... 2. Regulation of excess intracellular free cholesterol through the activity of acyl-CoA:cholesterol acyltransferase (ACAT) 3. Regulation of plasma cholesterol levels via LDL receptor-mediated uptake & HDL-mediated reverse transport (in liver). ...
Neonatal Hyperbilirubinemia and Organic Anion Transporting
... NY), kernicterus still occurs; these cases highlight the need for continued study of the etiology of hyperbilirubinemia.19 Neither hyperbilirubinemia nor kernicterus are reportable diseases, and there are no reliable sources of information providing national annual estimates.19 The primary risk fact ...
... NY), kernicterus still occurs; these cases highlight the need for continued study of the etiology of hyperbilirubinemia.19 Neither hyperbilirubinemia nor kernicterus are reportable diseases, and there are no reliable sources of information providing national annual estimates.19 The primary risk fact ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.