Y chromosome polymorphisms in medicine
... such as male sex determination (SRY) and spermatogenesis (i.e., genes of the azoospermia factor (AZF) regions of the long arm of the Y chromosome). Consequently mutations/deletions of these genes lead to sex reversal or spermatogenic failure (7±9). In addition, loss or rearrangements of the Y are al ...
... such as male sex determination (SRY) and spermatogenesis (i.e., genes of the azoospermia factor (AZF) regions of the long arm of the Y chromosome). Consequently mutations/deletions of these genes lead to sex reversal or spermatogenic failure (7±9). In addition, loss or rearrangements of the Y are al ...
TCF11/Nrf1 overexpression increases the intracellular
... this group, TCF11/Nrf1 can heterodimerise with small Maf transcription factors to more e¤ciently bind DNA target sequences [17]. We originally showed that TCF11/ Nrf1 can bind to the same target sequence as p45 NF-E2 in vitro (the NF-E2 site), both alone and in the presence of small Maf proteins [17 ...
... this group, TCF11/Nrf1 can heterodimerise with small Maf transcription factors to more e¤ciently bind DNA target sequences [17]. We originally showed that TCF11/ Nrf1 can bind to the same target sequence as p45 NF-E2 in vitro (the NF-E2 site), both alone and in the presence of small Maf proteins [17 ...
Genetic Analysis of Salt Tolerance in Arabidopsis
... and Zhu, 1997). Several salt-inducible genes show increased expression in sos1 mutants under salt stress (Liu and Zhu, 1997a). We have since completed a large-scale screening (z260,000 plants) in an attempt to identify all genetic loci mutations in which can result an sos phenotype. Altogether, 42 s ...
... and Zhu, 1997). Several salt-inducible genes show increased expression in sos1 mutants under salt stress (Liu and Zhu, 1997a). We have since completed a large-scale screening (z260,000 plants) in an attempt to identify all genetic loci mutations in which can result an sos phenotype. Altogether, 42 s ...
A mixed group ll/group III twintron in the Euglena
... of introns and the role of introns during gene evolution. The debate over this question has focused on two views of intron evolution: 'introns early' versus 'introns late'. In the introns early model, genes are viewed as being assembled from exons that code for structural or functional domains. Intr ...
... of introns and the role of introns during gene evolution. The debate over this question has focused on two views of intron evolution: 'introns early' versus 'introns late'. In the introns early model, genes are viewed as being assembled from exons that code for structural or functional domains. Intr ...
as Adobe PDF - Edinburgh Research Explorer
... 1999) and flies (Azpiazu and Frasch 1993). This high level of functional conservation suggests that the underlying transcriptional circuitry governing VM development may also be conserved. To date, most progress has been made in elucidating the genetic program required for VM development in Drosophi ...
... 1999) and flies (Azpiazu and Frasch 1993). This high level of functional conservation suggests that the underlying transcriptional circuitry governing VM development may also be conserved. To date, most progress has been made in elucidating the genetic program required for VM development in Drosophi ...
genetics - Krishikosh
... Dr. Dobzhansky, Professor of Zoology at Columbia University in New York City, was born in Russia in 1900. Educated at the University of Kiev, he began teaching and research at Kiev Agricultural Institute and the University of Leningrad. He came to the United States in 1927, worked with T. H. Morgan ...
... Dr. Dobzhansky, Professor of Zoology at Columbia University in New York City, was born in Russia in 1900. Educated at the University of Kiev, he began teaching and research at Kiev Agricultural Institute and the University of Leningrad. He came to the United States in 1927, worked with T. H. Morgan ...
Rhizopus Raw-Starch-Degrading Glucoamylase: Its
... tion, because it could directly convert starch ...
... tion, because it could directly convert starch ...
Assaying … promoter activity
... nimB and ORF5468 gene. We tested the stability of the integrated plasmid via a true breeding experiment. In this experiment, recombinant cells were grown at the non-permissive temperature in the absence of antibiotic selection for approximately 10 generations. Following this period, aliquots from th ...
... nimB and ORF5468 gene. We tested the stability of the integrated plasmid via a true breeding experiment. In this experiment, recombinant cells were grown at the non-permissive temperature in the absence of antibiotic selection for approximately 10 generations. Following this period, aliquots from th ...
Specific oligonucleotide primers for detection of endoglucanase
... endoglucanase gene of B. subtilis, G. stearothermophilus and P. campinasensis. Two PCR primers, EN1F and EN1R, were chosen that were predicted to specifically amplify a 1,311 bpDNA fragment of the B. Subtilis, G. stearothermophilus and P. campinasensis. The Genbank database (NCBI) search for complim ...
... endoglucanase gene of B. subtilis, G. stearothermophilus and P. campinasensis. Two PCR primers, EN1F and EN1R, were chosen that were predicted to specifically amplify a 1,311 bpDNA fragment of the B. Subtilis, G. stearothermophilus and P. campinasensis. The Genbank database (NCBI) search for complim ...
Chapter 14.
... Pleiotropy It is not surprising that a gene can affect a number of organism’s characteristics ...
... Pleiotropy It is not surprising that a gene can affect a number of organism’s characteristics ...
Molecular pathogenesis of liver adenomas and FNH - HAL
... inflammatory proteins were effectively secreted by the tumor (102). We also found that inflammatory HCAs more frequently developed in patients presenting a high body mass index and excessive alcohol consumption (82). These results suggest that alcohol intake and obesity could have a direct role in t ...
... inflammatory proteins were effectively secreted by the tumor (102). We also found that inflammatory HCAs more frequently developed in patients presenting a high body mass index and excessive alcohol consumption (82). These results suggest that alcohol intake and obesity could have a direct role in t ...
Ch15 ppt - WEB . WHRSD . ORG
... Pleiotropy It is not surprising that a gene can affect a number of organism’s characteristics ...
... Pleiotropy It is not surprising that a gene can affect a number of organism’s characteristics ...
Risk assessment - Office of the Gene Technology Regulator
... All events were characterised in relation to both the magnitude and probability of harm in the context of the controls proposed by the applicant to limit the spread and persistence of the GMOs in both time and space. This detailed consideration concluded that none of the sixteen events gave rise to ...
... All events were characterised in relation to both the magnitude and probability of harm in the context of the controls proposed by the applicant to limit the spread and persistence of the GMOs in both time and space. This detailed consideration concluded that none of the sixteen events gave rise to ...
Text S1.
... [2] or the 1000 Genomes Project [3]). Putatively functional genotypes are only counted if they occur in genes annotated as being associated with the phenotype. Second layer. These nodes represent genes, split into those annotated as high penetrance GH or low penetrance GL. Their values depend on lin ...
... [2] or the 1000 Genomes Project [3]). Putatively functional genotypes are only counted if they occur in genes annotated as being associated with the phenotype. Second layer. These nodes represent genes, split into those annotated as high penetrance GH or low penetrance GL. Their values depend on lin ...
Development and application of a positive
... transfection efficiencies and the low number of selectable markers. Presently, it is possible to stably transform four species of Plasmodium, the human parasite Plasmodium falciparum, the primate parasite Plasmodium knowlesi and two rodent malaria parasites, Plasmodium berghei and Plasmodium yoelii ...
... transfection efficiencies and the low number of selectable markers. Presently, it is possible to stably transform four species of Plasmodium, the human parasite Plasmodium falciparum, the primate parasite Plasmodium knowlesi and two rodent malaria parasites, Plasmodium berghei and Plasmodium yoelii ...
10.1 - My Haiku
... (colour and shape) and performed many test crosses, recording the ratios of phenotypes produced in subsequent generations. It was rather fortunate that these two traits happened to be on separate chromosomes (unlinked genes)! Remember back then he did not know about the contents of the nucleus. Chro ...
... (colour and shape) and performed many test crosses, recording the ratios of phenotypes produced in subsequent generations. It was rather fortunate that these two traits happened to be on separate chromosomes (unlinked genes)! Remember back then he did not know about the contents of the nucleus. Chro ...
Special Report on Genetics and: Gout 23 Selected Articles From 199
... Our purpose is to provide both general and focused information regarding the interplay between genetics, health, and the environment, including but not limited to nutrition. Genetics matter, but in most cases your lifestyle and environment matter even more. It’s often said, “Genetics loads the gun, ...
... Our purpose is to provide both general and focused information regarding the interplay between genetics, health, and the environment, including but not limited to nutrition. Genetics matter, but in most cases your lifestyle and environment matter even more. It’s often said, “Genetics loads the gun, ...
Genetics chapt10
... multiple genes Polygenic inheritance is common with characteristics that show great variety within the population. ...
... multiple genes Polygenic inheritance is common with characteristics that show great variety within the population. ...
multicopy gene family evolution on primate y chromosomes
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
The Ethylene Signal Transduction Pathway in Plants
... A C C oxidase genes by expression of antisense RNA (7) will provide a simple means to control the ripening of fruits in a variety of plants (4, 8). By contrast, biochemical approaches toward dissection of the mechanisms by ...
... A C C oxidase genes by expression of antisense RNA (7) will provide a simple means to control the ripening of fruits in a variety of plants (4, 8). By contrast, biochemical approaches toward dissection of the mechanisms by ...
Traversing the conceptual divide between biological and
... phenotype in the form of small shriveled wings and excess bristle numbers. Genetic studies with wild-type and mutant Drosophila confirm the interaction. The study by Bondos et al.(19) illustrates how powerful the yeast two-hybrid system is for identifying proteins that interact with a protein of int ...
... phenotype in the form of small shriveled wings and excess bristle numbers. Genetic studies with wild-type and mutant Drosophila confirm the interaction. The study by Bondos et al.(19) illustrates how powerful the yeast two-hybrid system is for identifying proteins that interact with a protein of int ...
Growth medium composition-determined regulatory mechanisms
... muconolactone isomerase and catechol 1,2-dioxygenase, respectively (Houghton et al., 1995). The induction of this operon, which is σ&%-independent, requires a LysR family transcriptional activator, CatR, and an inducer molecule, cis,cis-muconate (CCM), an intermediate of the ortho-pathway (Rothmel e ...
... muconolactone isomerase and catechol 1,2-dioxygenase, respectively (Houghton et al., 1995). The induction of this operon, which is σ&%-independent, requires a LysR family transcriptional activator, CatR, and an inducer molecule, cis,cis-muconate (CCM), an intermediate of the ortho-pathway (Rothmel e ...
continued
... 10.1 What Is the Physical Basis of Inheritance? Genes are sequences of nucleotides at specific locations on chromosomes – Inheritance is the process by which the characteristics of individuals are passed to their offspring – A gene is a unit of heredity that encodes information needed to produce ...
... 10.1 What Is the Physical Basis of Inheritance? Genes are sequences of nucleotides at specific locations on chromosomes – Inheritance is the process by which the characteristics of individuals are passed to their offspring – A gene is a unit of heredity that encodes information needed to produce ...
Probable presence of an ubiquitous cryptic mitochondrial gene on
... gene has been named gau for gene antisense ubiquitous in mtDNAs. The length of the deduced protein is approximately 100 amino acids. In vertebrates, several stop codons have been found in the mt gau region, and potentially functional gau regions have been found in nuclear genomes. However, a recent ...
... gene has been named gau for gene antisense ubiquitous in mtDNAs. The length of the deduced protein is approximately 100 amino acids. In vertebrates, several stop codons have been found in the mt gau region, and potentially functional gau regions have been found in nuclear genomes. However, a recent ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.