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... workers [39]. Alternatively, high intra-colony variability in worker phenotypes could be beneficial because it results in a more efficient workforce [40,41]. These factors could lead to increased recombination rates in the vicinity of genes specifically involved in worker phenotypes. Some studies ha ...
... workers [39]. Alternatively, high intra-colony variability in worker phenotypes could be beneficial because it results in a more efficient workforce [40,41]. These factors could lead to increased recombination rates in the vicinity of genes specifically involved in worker phenotypes. Some studies ha ...
Beyond The Classical Cystic Fibrosis
... Since 1989, it has become well known that CF is an ion channel disorder caused by mutations in the gene for the CF transmembrane conductance regulator (CFTR) [16]. The CFTR gene is located on the long (q) arm of chromosome 7 (7q31.2) [17,18]. ...
... Since 1989, it has become well known that CF is an ion channel disorder caused by mutations in the gene for the CF transmembrane conductance regulator (CFTR) [16]. The CFTR gene is located on the long (q) arm of chromosome 7 (7q31.2) [17,18]. ...
The Isolation of Mutagen-Sensitive nuv Mutants of
... produce a nonsporulating mycelial “mat.” Mycelial “plugs” were c u t out from the mats using the wide end of a sterile Pasteur pipette. The plugswere transferred in duplicate onto M M plates containing various concentrations of M N N G or 4-NQO and incubated for 48 hr at 3 7 ” . The diameters of the ...
... produce a nonsporulating mycelial “mat.” Mycelial “plugs” were c u t out from the mats using the wide end of a sterile Pasteur pipette. The plugswere transferred in duplicate onto M M plates containing various concentrations of M N N G or 4-NQO and incubated for 48 hr at 3 7 ” . The diameters of the ...
Full Text - The International Journal of Developmental Biology
... sequentially coordinated to give rise to a functional seed in a matter of few weeks. Any of these processes is so intricately complex and precisely regulated that it becomes no wonder that each involves more specific genes and cellular processes than any other function in the plant life cycle. While ...
... sequentially coordinated to give rise to a functional seed in a matter of few weeks. Any of these processes is so intricately complex and precisely regulated that it becomes no wonder that each involves more specific genes and cellular processes than any other function in the plant life cycle. While ...
Novel Regulation of Cardiac Metabolism and Homeostasis by the
... cardiovascular system. The AM receptor calcitonin receptor-like receptor associates with receptor activity-modifying protein (RAMP), one of the subtypes of regulatory proteins. Among knockout mice (−/−) of RAMPs, only RAMP2−/− is embryonically lethal with cardiovascular abnormalities that are the sa ...
... cardiovascular system. The AM receptor calcitonin receptor-like receptor associates with receptor activity-modifying protein (RAMP), one of the subtypes of regulatory proteins. Among knockout mice (−/−) of RAMPs, only RAMP2−/− is embryonically lethal with cardiovascular abnormalities that are the sa ...
Determining presence/absence threshold for your dataset
... In PanCGHweb there are two ways to determine the presence/absence calling threshold. One is based on Receiver Operating Curves (ROC) generated for microarray data of reference strains and the other is based on plotting histograms of presence of scores for ortholog groups of reference strains. Note: ...
... In PanCGHweb there are two ways to determine the presence/absence calling threshold. One is based on Receiver Operating Curves (ROC) generated for microarray data of reference strains and the other is based on plotting histograms of presence of scores for ortholog groups of reference strains. Note: ...
Multiple Roles of the Y Chromosome in the Biology of
... It is generally accepted that the sex chromosomes of most animals arose from a couple of homologous autosomes after the acquisition of a dominant sex determination gene[17,18] and that the Y chromosome is the result of the degeneration of one of them[19,20,21]. Its degeneration would be a consequenc ...
... It is generally accepted that the sex chromosomes of most animals arose from a couple of homologous autosomes after the acquisition of a dominant sex determination gene[17,18] and that the Y chromosome is the result of the degeneration of one of them[19,20,21]. Its degeneration would be a consequenc ...
coloured foal booklet - British Skewbald and Piebald Association
... Some familiar terms used in breeding coloured foals So, now you’d like to breed yourself a coloured foal? Well – in the case of the Tobiano we have to start with one coloured parent at least. Whilst this may be an obvious statement on the surface – it is a fact that you could breed two solid colour ...
... Some familiar terms used in breeding coloured foals So, now you’d like to breed yourself a coloured foal? Well – in the case of the Tobiano we have to start with one coloured parent at least. Whilst this may be an obvious statement on the surface – it is a fact that you could breed two solid colour ...
Centromere Locations and Associated Chromosome
... cannot map any genes lost in events such as the hypothetical loss of a centromere (see Figure 1). This means that we are unlikely to be able to discover the precise centromere locations of the three A. lyrata chromosomes involved in fusions. However, fusion events are expected to cause loss of a sma ...
... cannot map any genes lost in events such as the hypothetical loss of a centromere (see Figure 1). This means that we are unlikely to be able to discover the precise centromere locations of the three A. lyrata chromosomes involved in fusions. However, fusion events are expected to cause loss of a sma ...
Note for Guidance on the Quality, Preclinical and Clinical
... The design of the gene transfer product forms an integral part of the rationale for the development of a gene transfer medicinal product. Information relating to the suitability of the vector system and of the delivery system should be provided. Data on the control and stability of gene expression s ...
... The design of the gene transfer product forms an integral part of the rationale for the development of a gene transfer medicinal product. Information relating to the suitability of the vector system and of the delivery system should be provided. Data on the control and stability of gene expression s ...
Databases_what_and_w..
... come from the DNA via RNA. • Changes in DNA cause changes in proteins. • Changes in proteins cause changes in phenotypes. ...
... come from the DNA via RNA. • Changes in DNA cause changes in proteins. • Changes in proteins cause changes in phenotypes. ...
Canadian journal of Microbiology
... management of this pathogen is essential. Public concern over the use of chemical pesticides together with the potential for acquiring resistance to these compounds has led to renewed interest in bacterial antagonists like PA23 for biocontrol. Biological approaches to disease management have previou ...
... management of this pathogen is essential. Public concern over the use of chemical pesticides together with the potential for acquiring resistance to these compounds has led to renewed interest in bacterial antagonists like PA23 for biocontrol. Biological approaches to disease management have previou ...
29th International Conference on Animal Genetics ISAG2004/TOKYO
... The Chicken Genome Sequence – Dave Burt (Roslin Institute) ...
... The Chicken Genome Sequence – Dave Burt (Roslin Institute) ...
The Coat of Many Colors
... Again, keep in mind as you continue to read that the merle allele is NOT a color allele. I know we’ve said this before, but it’s worth repeating! We’ll need a few definitions to understand how merle works. For example, we briefly mentioned the meaning of allele earlier. Here’s an expanded definition ...
... Again, keep in mind as you continue to read that the merle allele is NOT a color allele. I know we’ve said this before, but it’s worth repeating! We’ll need a few definitions to understand how merle works. For example, we briefly mentioned the meaning of allele earlier. Here’s an expanded definition ...
Using Drosophila to Understand the Genetics of Circadian Rhythms
... SLEEP THAT IS NOT ALREADY AVAILABLE IN THE MUCHREVIEWED AREA OF USING DROSOPHILA TO STUDY CIRCADIAN RHYTHMS AND SLEEP?” First, most reviews focus largely on the molecular basis of circadian rhythms (see for example1,2)), so that a review tailored for an audience interested in sleep may be appropriat ...
... SLEEP THAT IS NOT ALREADY AVAILABLE IN THE MUCHREVIEWED AREA OF USING DROSOPHILA TO STUDY CIRCADIAN RHYTHMS AND SLEEP?” First, most reviews focus largely on the molecular basis of circadian rhythms (see for example1,2)), so that a review tailored for an audience interested in sleep may be appropriat ...
Word - The Open University
... two levels, and in so doing we shall be jumping from the fundamental work of 19th century biologists, who could only trace phenotypes, to that of present-day geneticists, who work at the level of the gene. We begin with one of the simplest known examples of inheritance, that of grain colour in maize ...
... two levels, and in so doing we shall be jumping from the fundamental work of 19th century biologists, who could only trace phenotypes, to that of present-day geneticists, who work at the level of the gene. We begin with one of the simplest known examples of inheritance, that of grain colour in maize ...
Comparative Genomics
... We can better understand evolution/ speciation We can find important, functional regions of the sequence (codons, promoters, regulatory regions) It can help us locate genes in other species that are missing or not welldefined (also through comparison and alignments). Quality control! ...
... We can better understand evolution/ speciation We can find important, functional regions of the sequence (codons, promoters, regulatory regions) It can help us locate genes in other species that are missing or not welldefined (also through comparison and alignments). Quality control! ...
Rapid generation of nested chromosomal
... is not shown). In a small fraction of random integrations, tk-loxP-puro is expected to insert in the orientation shown, generating a chromosome that could delete the genes between the two loxP sites. Both tk genes are lost with the deletion, generating cells that are resistant to selection for the n ...
... is not shown). In a small fraction of random integrations, tk-loxP-puro is expected to insert in the orientation shown, generating a chromosome that could delete the genes between the two loxP sites. Both tk genes are lost with the deletion, generating cells that are resistant to selection for the n ...
No Slide Title
... attacks never develop. Other treatments are designed to control an attack after it starts. ...
... attacks never develop. Other treatments are designed to control an attack after it starts. ...
Zebrafish Collagen Type I: Molecular and Biochemical
... around a central axis11. In the endoplasmic reticulum, type I collagen is synthesized as a pro-collagen molecule characterized by the presence of N- and C-propeptides flanking the triple helical region via two short telopeptides (N- and C- telopeptide). In particular, the C-propeptide contains a var ...
... around a central axis11. In the endoplasmic reticulum, type I collagen is synthesized as a pro-collagen molecule characterized by the presence of N- and C-propeptides flanking the triple helical region via two short telopeptides (N- and C- telopeptide). In particular, the C-propeptide contains a var ...
Gene Mapping, Marker-Assisted Selection, Gene Cloning, Genetic
... of 100 cDNA clones, 11 EST markers were obtained (Karsi et al. 1998; Liu et al. 1999e). RAPD markers were evaluated (Welsh and McClelland 1990; Williams et al. 1990) for their application in catfish gene mapping. Polymorphic rates are low among strains of channel catfish, but high between channel an ...
... of 100 cDNA clones, 11 EST markers were obtained (Karsi et al. 1998; Liu et al. 1999e). RAPD markers were evaluated (Welsh and McClelland 1990; Williams et al. 1990) for their application in catfish gene mapping. Polymorphic rates are low among strains of channel catfish, but high between channel an ...
A Single Arabidopsis Gene Encodes Two
... prenyldiphosphate synthases that mainly produce C25 geranylfarnesyl diphosphate (GFPP) or even longer products (Nagel et al., 2015; Wang et al., 2016). The sG11 protein lacks 19 residues predicted to be present in the N-terminal region of the mature G11 enzyme (Fig. 2A; Supplemental Fig. S2). While ...
... prenyldiphosphate synthases that mainly produce C25 geranylfarnesyl diphosphate (GFPP) or even longer products (Nagel et al., 2015; Wang et al., 2016). The sG11 protein lacks 19 residues predicted to be present in the N-terminal region of the mature G11 enzyme (Fig. 2A; Supplemental Fig. S2). While ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.