Expert Reviews in Molecular Medicine Androgenetic alopecia
... loss. Less commonly, the frontal hairline can be preserved (Ref. 11). ...
... loss. Less commonly, the frontal hairline can be preserved (Ref. 11). ...
Two glucose/xylose transporter genes from the yeast Candida
... from an environmental and from an economic point of view because hemicellulose is a major component of low-value agricultural and wood-pulping wastes [1,2]. Ideally Saccharomyces cerevisiae, as the most efficient glucose fermenter and capable of withstanding both high ethanol concentrations and the ...
... from an environmental and from an economic point of view because hemicellulose is a major component of low-value agricultural and wood-pulping wastes [1,2]. Ideally Saccharomyces cerevisiae, as the most efficient glucose fermenter and capable of withstanding both high ethanol concentrations and the ...
Congenital hereditary cataracts
... organisms. The mouse is such a good model because of its similarity (as a mammal) and its genetic characterization. This review brings together our genetic and developmental knowledge of congenital, human cataracts with the corresponding mouse models. First, early events will be influenced by genes ...
... organisms. The mouse is such a good model because of its similarity (as a mammal) and its genetic characterization. This review brings together our genetic and developmental knowledge of congenital, human cataracts with the corresponding mouse models. First, early events will be influenced by genes ...
An Update on the Hereditary Spastic Paraplegias: New Genes and
... candidate genes have been subsequently confirmed in independent studies, including REEP2,33 DDHD2,34,35 and KIF1C.36 The investigators also used the network to examine the similarity of HSP genes (seed plus candidate) to other common neurological disorders. They found that there was a significant ov ...
... candidate genes have been subsequently confirmed in independent studies, including REEP2,33 DDHD2,34,35 and KIF1C.36 The investigators also used the network to examine the similarity of HSP genes (seed plus candidate) to other common neurological disorders. They found that there was a significant ov ...
Agrobacterium: nature`s genetic engineer
... The identification of the TIP raised many interesting questions. Many laboratories studied the Ti plasmid. Some focused on the Ti plasmid from strains that induced tumors that synthesized octopine (octopine strains like A6 and B6). Others studied strains that induced nopaline synthesizing tumors, li ...
... The identification of the TIP raised many interesting questions. Many laboratories studied the Ti plasmid. Some focused on the Ti plasmid from strains that induced tumors that synthesized octopine (octopine strains like A6 and B6). Others studied strains that induced nopaline synthesizing tumors, li ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
... in the cytosol may also have its product targeted to the plastid. In such a case, the plastid and cytosolic versions of the protein are closely related and may be identical and transcribed from a single locus, and, consequently, they are difficult to trace individually. For this reason, relatively l ...
... in the cytosol may also have its product targeted to the plastid. In such a case, the plastid and cytosolic versions of the protein are closely related and may be identical and transcribed from a single locus, and, consequently, they are difficult to trace individually. For this reason, relatively l ...
Increased transcription rates correlate with increased reversion rates
... leuB and argH mRNA synthesis were determined using half-lives and concentrations, during exponential growth and at several time points during 30 min of amino acid starvation. Changes in mRNA concentration were primarily due to increased mRNA synthesis and not to increased stability. Four strains of ...
... leuB and argH mRNA synthesis were determined using half-lives and concentrations, during exponential growth and at several time points during 30 min of amino acid starvation. Changes in mRNA concentration were primarily due to increased mRNA synthesis and not to increased stability. Four strains of ...
Gene Name
... frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleas ...
... frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleas ...
Preferential X-chromosome inactivation, DNA
... development. Dispersed repetitive sequences inherited from the sperm are demethylated in primordial germ cells of the progeny at some time before 11.5 days' gestation (Monk etal. 1987). Sperm-derived LI sequences are also demethylated either before, or soon after, the delineation of extra-embryonic ...
... development. Dispersed repetitive sequences inherited from the sperm are demethylated in primordial germ cells of the progeny at some time before 11.5 days' gestation (Monk etal. 1987). Sperm-derived LI sequences are also demethylated either before, or soon after, the delineation of extra-embryonic ...
Document
... KEY CONCEPT Genes encode proteins that produce a diverse range of traits. A gene is a segment of DNA that tells the cell how to make a particular polypeptide. The location of a gene on a chromosome is called a locus. A gene has the same locus on both chromosomes in a pair of homologous chromosomes. ...
... KEY CONCEPT Genes encode proteins that produce a diverse range of traits. A gene is a segment of DNA that tells the cell how to make a particular polypeptide. The location of a gene on a chromosome is called a locus. A gene has the same locus on both chromosomes in a pair of homologous chromosomes. ...
what is alignment? - UWI St. Augustine
... Significance of local sequence alignment •In global alignment, an attempt is made to align the entire sequences, as many characters as possible. • In local alignment, stretches of sequence with the highest density of matches are given the highest priority, •generating one or more islands of matches ...
... Significance of local sequence alignment •In global alignment, an attempt is made to align the entire sequences, as many characters as possible. • In local alignment, stretches of sequence with the highest density of matches are given the highest priority, •generating one or more islands of matches ...
valve margin
... •In flies and plants, juxtaposition of dorsal and ventral surfaces induces formation of an organizing margin. •The organizing margin controls outgrowth of the appendage. ...
... •In flies and plants, juxtaposition of dorsal and ventral surfaces induces formation of an organizing margin. •The organizing margin controls outgrowth of the appendage. ...
Distribution and structural variation of the she pathogenicity island in
... coli (EHEC), enteropathogenic E. coli (EPEC), enteroinvasive E. coli (EIEC), Yersinia enterocolitica and Salmonella enterica serovar Typhimurium. The study showed that the she PAI has undergone a variety of structural changes, de®ned by the presence or absence of speci®c marker genes in the PAI. The ...
... coli (EHEC), enteropathogenic E. coli (EPEC), enteroinvasive E. coli (EIEC), Yersinia enterocolitica and Salmonella enterica serovar Typhimurium. The study showed that the she PAI has undergone a variety of structural changes, de®ned by the presence or absence of speci®c marker genes in the PAI. The ...
A Cladistic Analysis of Phenotype Associations with
... organized into a cladogram that represents the evolutionary relationships between the observed haplotypes. Anymutation causing a significant phenotypic effect should be imbedded within the same historical structure defined by the cladogram. We showed, in the first paper of this series,how to use the ...
... organized into a cladogram that represents the evolutionary relationships between the observed haplotypes. Anymutation causing a significant phenotypic effect should be imbedded within the same historical structure defined by the cladogram. We showed, in the first paper of this series,how to use the ...
Swartzlander_ku_0099D_15051_DATA_1
... Genomic regions containing desatF and eloF, among other genes, have been identified by quantitative trait locus (QTL) studies as potentially contributing to production of the D. sechellia pheromone 7,11-HD. In this study I tested the hypothesis that desatF and eloF influence reproductive isolation b ...
... Genomic regions containing desatF and eloF, among other genes, have been identified by quantitative trait locus (QTL) studies as potentially contributing to production of the D. sechellia pheromone 7,11-HD. In this study I tested the hypothesis that desatF and eloF influence reproductive isolation b ...
An Introduction to RNA Interference (RNAi)
... translate knowledge on normal function into the development of even safer and more efficacious therapeutics. Indeed, due to their central importance in many cell biological processes, an unprecedented research effort is aimed at elucidating additional RNA biology. RNAi opens up many new targets for ...
... translate knowledge on normal function into the development of even safer and more efficacious therapeutics. Indeed, due to their central importance in many cell biological processes, an unprecedented research effort is aimed at elucidating additional RNA biology. RNAi opens up many new targets for ...
DNA cytosine methylation in plant development
... H3K9 methyltransferase that stabilizes cytosine methylation, particularly in CHG trinucleotides. Although SUVH4/KYP is the major H3K9 methyltransferase in Arabidopsis, two related histone methyltransferases, SUVH5 and SUVH6, are needed for maintaining non-CG methylation at specific loci (Huettel et ...
... H3K9 methyltransferase that stabilizes cytosine methylation, particularly in CHG trinucleotides. Although SUVH4/KYP is the major H3K9 methyltransferase in Arabidopsis, two related histone methyltransferases, SUVH5 and SUVH6, are needed for maintaining non-CG methylation at specific loci (Huettel et ...
American College of Medical Genetics standards
... laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does not necessarily assure a successful medical outcome. These Standards and Guidelines should not be considered inclusive of all proper procedures ...
... laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does not necessarily assure a successful medical outcome. These Standards and Guidelines should not be considered inclusive of all proper procedures ...
An accessible database for mouse and human whole transcriptome
... is an important tool in quantitative studies of DNA and RNA molecules; especially in transcriptome studies, where different primer combinations allow identification of specific transcripts such as splice variants or precursor messenger RNA. Several softwares that implement various rules for optimal ...
... is an important tool in quantitative studies of DNA and RNA molecules; especially in transcriptome studies, where different primer combinations allow identification of specific transcripts such as splice variants or precursor messenger RNA. Several softwares that implement various rules for optimal ...
III. Linkage
... - each X has a gene – the Xic (X-inactivation center). - this is ‘on’ in inactivated X’s… it produces an RNA (Xist) that binds with the chromosomes, making it inaccessible to transcription enzymes. - this RNA is NOT translated – it is functional as an RNA molecule. - of course, this just pushes the ...
... - each X has a gene – the Xic (X-inactivation center). - this is ‘on’ in inactivated X’s… it produces an RNA (Xist) that binds with the chromosomes, making it inaccessible to transcription enzymes. - this RNA is NOT translated – it is functional as an RNA molecule. - of course, this just pushes the ...
Practice exam 3 key
... (3 pts) Leaves single-stranded overhangs (or 'sticky ends') (1 pt); these ends are complementary (will hybridize) (1 pt); can be used to join 2 DNA fragments cut with EcoRI (with the same restriction enzyme) (1 pt). ...
... (3 pts) Leaves single-stranded overhangs (or 'sticky ends') (1 pt); these ends are complementary (will hybridize) (1 pt); can be used to join 2 DNA fragments cut with EcoRI (with the same restriction enzyme) (1 pt). ...
American College of Medical Genetics standards and guidelines for
... laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does not necessarily assure a successful medical outcome. These Standards and Guidelines should not be considered inclusive of all proper procedures ...
... laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does not necessarily assure a successful medical outcome. These Standards and Guidelines should not be considered inclusive of all proper procedures ...
Drosophila rhino Encodes a Female-Specific Chromo
... subfamily of chromo box proteins. rhino (rhi) is expressed only in females and chiefly in the germline, thus providing a new tool to dissect the role of chromo-domain proteins in development. Mutations in rhi disrupt eggshell and embryonic patterning and arrest nurse cell nuclei during a stage-speci ...
... subfamily of chromo box proteins. rhino (rhi) is expressed only in females and chiefly in the germline, thus providing a new tool to dissect the role of chromo-domain proteins in development. Mutations in rhi disrupt eggshell and embryonic patterning and arrest nurse cell nuclei during a stage-speci ...
G enetics - Lantern Publishing
... Two copies of the altered allele must be present for an individual to be affected by a recessive disorder. That individual would be classified as homozygous recessive for that disorder. Heterozygous individuals who only possess one altered allele and a normally functioning allele will not display th ...
... Two copies of the altered allele must be present for an individual to be affected by a recessive disorder. That individual would be classified as homozygous recessive for that disorder. Heterozygous individuals who only possess one altered allele and a normally functioning allele will not display th ...
Relative Paucity of Genes Causing Inviability in Hybrids
... genes from another species. Thus, if sex-limited F1 sterility and inviability involves partially recessive alleles, it must be based on X-linked genes of that type interacting with semidominant alleles from another species. Testing such genetic interactions [posited by Turelli and Orr (1995) to be a ...
... genes from another species. Thus, if sex-limited F1 sterility and inviability involves partially recessive alleles, it must be based on X-linked genes of that type interacting with semidominant alleles from another species. Testing such genetic interactions [posited by Turelli and Orr (1995) to be a ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.