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Gro and Eve co-regulate early boundaries - Development
... 1806 M. Kobayashi and others An alanine/proline-rich repression domain was mapped in Eve using transient transfection assays (Han and Manley, 1993; Jaynes and O’Farrell, 1991), and similar repression domains have been found in other proteins (Hanna-Rose and Hansen, 1996). For one of these repressor ...
... 1806 M. Kobayashi and others An alanine/proline-rich repression domain was mapped in Eve using transient transfection assays (Han and Manley, 1993; Jaynes and O’Farrell, 1991), and similar repression domains have been found in other proteins (Hanna-Rose and Hansen, 1996). For one of these repressor ...
Method for identification of origins of replication and genes
... When the strict defmition of DnaA box was used, a single 500 base pairs long region, which contains three DnaA binding sites and is located at 774'1J!,7 in the genome was identified (Figure 8). In addition ...
... When the strict defmition of DnaA box was used, a single 500 base pairs long region, which contains three DnaA binding sites and is located at 774'1J!,7 in the genome was identified (Figure 8). In addition ...
Student Handout
... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
Nodal signaling and the zebrafish organizer
... causes cyclopia accompanied by a loss of ventral forebrain and floor plate (Hatta et al., 1991). Several subsequent screens identified additional alleles induced by ENU and gamma-rays (Brand et al., 1996; Schier et al., 1996; Talbot et al., 1998). In addition to the ventral neural tube defects in cy ...
... causes cyclopia accompanied by a loss of ventral forebrain and floor plate (Hatta et al., 1991). Several subsequent screens identified additional alleles induced by ENU and gamma-rays (Brand et al., 1996; Schier et al., 1996; Talbot et al., 1998). In addition to the ventral neural tube defects in cy ...
Full Text - The International Journal of Developmental Biology
... processes is so intricately complex and precisely regulated that it becomes no wonder that each involves more specific genes and cellular processes than any other function in the plant life cycle. While variability generation - the evolutionary output of the sexual cycle - is the same as in any othe ...
... processes is so intricately complex and precisely regulated that it becomes no wonder that each involves more specific genes and cellular processes than any other function in the plant life cycle. While variability generation - the evolutionary output of the sexual cycle - is the same as in any othe ...
The molecular basis of human retinal and vitreoretinal
... molecular basis of many human disorders, including retinal and vitreoretinal degenerations and dysfunctions. Although belonging to the group of orphan diseases, they affect probably more than two million people worldwide. Most excitingly, treatment of a particular form of congenital retinal degenera ...
... molecular basis of many human disorders, including retinal and vitreoretinal degenerations and dysfunctions. Although belonging to the group of orphan diseases, they affect probably more than two million people worldwide. Most excitingly, treatment of a particular form of congenital retinal degenera ...
Weird Alleles, and Intro to Punnett Squares
... will come back a bit next week, and MCAS may choose to use it. So just be aware that these are alleles just like any other, they still stand for different base sequences coding for different versions of a protein, they’re just written by scientists to be more specific. ...
... will come back a bit next week, and MCAS may choose to use it. So just be aware that these are alleles just like any other, they still stand for different base sequences coding for different versions of a protein, they’re just written by scientists to be more specific. ...
Regulation of Ovule Development
... Ovule development in Arabidopsis and other plants has been the focus of classic and molecular genetic analyses in recent years. This has been an exciting time to be involved in plant developmental biology, because many genetic pathways and regulatory mechanisms have been elucidated. Continued studie ...
... Ovule development in Arabidopsis and other plants has been the focus of classic and molecular genetic analyses in recent years. This has been an exciting time to be involved in plant developmental biology, because many genetic pathways and regulatory mechanisms have been elucidated. Continued studie ...
Thiele et al.: `Genome-scale reconstruction of E. coli`s transcriptional
... Sulfate is the only ionic compound associated with it PDBID: 2D1P. mnmA aka TrmU: monomer based on molecular weight [30] (in the paper they carry out the characterization and purification): crystal (no structure; one crystal contained 1 mnmA-tRNA complex) [29]. The thioredoxin system had to be added ...
... Sulfate is the only ionic compound associated with it PDBID: 2D1P. mnmA aka TrmU: monomer based on molecular weight [30] (in the paper they carry out the characterization and purification): crystal (no structure; one crystal contained 1 mnmA-tRNA complex) [29]. The thioredoxin system had to be added ...
Running Header: WHAT ARE THE GENETICS BEHIND DYSLEXIA
... (2009), DCDC2 was looked at in 72 German dyslexics and the results display that DCDC2 played a role within the dyslexics. This also increases the thought of damaged neuronal migration as a possible cause of dyslexia. Recent research also finds evidence of DCDC2’s association of mathematics (Marino e ...
... (2009), DCDC2 was looked at in 72 German dyslexics and the results display that DCDC2 played a role within the dyslexics. This also increases the thought of damaged neuronal migration as a possible cause of dyslexia. Recent research also finds evidence of DCDC2’s association of mathematics (Marino e ...
The pleiotropic structure of the genotype–phenotype
... rather than by removing or creating an entire gene. Mutational pleiotropy tends to be smaller than gene plei‑ otropy (for examples, see REF. 25). nevertheless, one can argue that the pleiotropy of knockout genotypes gives an upper limit of mutational pleiotropy, as it is plausible that a complete lo ...
... rather than by removing or creating an entire gene. Mutational pleiotropy tends to be smaller than gene plei‑ otropy (for examples, see REF. 25). nevertheless, one can argue that the pleiotropy of knockout genotypes gives an upper limit of mutational pleiotropy, as it is plausible that a complete lo ...
sensitivity of tryptophan, tyrosine and phenylalanine
... biosynthesis are needed for expression of resistance to PEA, we isolated from the PEA-resistant strain XP300-26C two classes of mutant strains. First, since tryptophan biosynthesis shares several common steps with phenylalanine and tyrosine biosynthesis, we wanted to determine whether only those ste ...
... biosynthesis are needed for expression of resistance to PEA, we isolated from the PEA-resistant strain XP300-26C two classes of mutant strains. First, since tryptophan biosynthesis shares several common steps with phenylalanine and tyrosine biosynthesis, we wanted to determine whether only those ste ...
The Johns Hopkins University - American University of Beirut
... • You need to understand the data they have, and how it is organized • There are often many ways to get to an answer. • Route to get there is not always obvious, but you need to think of alternatives and traps. • Use some query language – each system has its own. • Retrieve data in a specified forma ...
... • You need to understand the data they have, and how it is organized • There are often many ways to get to an answer. • Route to get there is not always obvious, but you need to think of alternatives and traps. • Use some query language – each system has its own. • Retrieve data in a specified forma ...
Complementary hierarchical clustering
... Before delving into the details of this procedure, we will give a very brief review of clustering methods. Further details on cluster analysis and various clustering methods can be found in Hastie and others (2001) and Gordon (1999). Cluster analysis is an unsupervised learning procedure with the go ...
... Before delving into the details of this procedure, we will give a very brief review of clustering methods. Further details on cluster analysis and various clustering methods can be found in Hastie and others (2001) and Gordon (1999). Cluster analysis is an unsupervised learning procedure with the go ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
... We have previously described the isolation and structure of cosmid clones that constitute a 60 kb contig containing agouti exons 1B, 1C, 2, 3 and 4 (Miller et al., 1993) (The agouti exon nomenclature used in the present work differs from that used previously; the rationale is summarized in Fig. 1). ...
... We have previously described the isolation and structure of cosmid clones that constitute a 60 kb contig containing agouti exons 1B, 1C, 2, 3 and 4 (Miller et al., 1993) (The agouti exon nomenclature used in the present work differs from that used previously; the rationale is summarized in Fig. 1). ...
Multiplex PCR for specific identification and determination of mating
... Gramaje et al., 2009, 2012). Phaeoacremonium spp. occurring on grapevines have been extensively studied. Since the description of Phaeoacremonium, the number of species in this genus has increased to 36 (www.mycobank.org), of which 25 were described from grapevines with esca or Petri disease symptom ...
... Gramaje et al., 2009, 2012). Phaeoacremonium spp. occurring on grapevines have been extensively studied. Since the description of Phaeoacremonium, the number of species in this genus has increased to 36 (www.mycobank.org), of which 25 were described from grapevines with esca or Petri disease symptom ...
Molecular Cloning and Expression Analysis of IgD in Nile
... heavy chains showed the highest similarity to Siniperca chuatsi. Quantitative real-time PCR (qRT-PCR) analysis showed that On-mIgD expression occurred predominately in head kidney, thymus, spleen, and kidney. After Streptococcus agalactiae infection, transcripts of On-mIgD increased and reached its ...
... heavy chains showed the highest similarity to Siniperca chuatsi. Quantitative real-time PCR (qRT-PCR) analysis showed that On-mIgD expression occurred predominately in head kidney, thymus, spleen, and kidney. After Streptococcus agalactiae infection, transcripts of On-mIgD increased and reached its ...
LIST OF CHECK-UP QUESTIONS for
... Answers multiple tests, choose and indicate the correct answer/statement, please: 1. The non-membranous organelles are: a) ribosomes; CORRECT b) Golgi body; c) lysosomes; d) Endoplasmic reticulum; e) nucleus 2. Chloroplasts and mitochondria both NOT: a) are found in plant cells; b) have two membrane ...
... Answers multiple tests, choose and indicate the correct answer/statement, please: 1. The non-membranous organelles are: a) ribosomes; CORRECT b) Golgi body; c) lysosomes; d) Endoplasmic reticulum; e) nucleus 2. Chloroplasts and mitochondria both NOT: a) are found in plant cells; b) have two membrane ...
Molecular Genetics of Bipolar Disorder and Related Traits
... especially now that the draft sequence of the human genome is available (7, 8). The human genome consists of 46 chromosomes; 22 pairs of autosomal chromosomes and 2 sex chromosomes. These are built up of ~3.3 billion base pairs of DNA that in turn code for about 20,000 - 25,000 protein-coding genes, ...
... especially now that the draft sequence of the human genome is available (7, 8). The human genome consists of 46 chromosomes; 22 pairs of autosomal chromosomes and 2 sex chromosomes. These are built up of ~3.3 billion base pairs of DNA that in turn code for about 20,000 - 25,000 protein-coding genes, ...
Alarmingly High Segregation Frequencies of Quinolone Resistance
... Antibiotic resistance poses a major threat to human health. It is therefore important to characterize the frequency of resistance within natural bacterial environments. Many studies have focused on characterizing the frequencies with which horizontally acquired resistance genes segregate within natu ...
... Antibiotic resistance poses a major threat to human health. It is therefore important to characterize the frequency of resistance within natural bacterial environments. Many studies have focused on characterizing the frequencies with which horizontally acquired resistance genes segregate within natu ...
Puffs and PCR: the in vivo dynamics of early gene
... The RNA preparation is derived from the method of Richards et al. (1983). Tubes were allowed to thaw on ice and then vortexed vigorously, which was as effective for the extraction of RNA as conventional grinding, and reduced variability resulting from debris sticking to the piston (data not shown). ...
... The RNA preparation is derived from the method of Richards et al. (1983). Tubes were allowed to thaw on ice and then vortexed vigorously, which was as effective for the extraction of RNA as conventional grinding, and reduced variability resulting from debris sticking to the piston (data not shown). ...
redundancy and regulatory interactions between two
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
Nonsensemediated decay of glutathione peroxidase 1 mRNA in the
... ef®ciency with which the selenocysteine (Sec) UGA codon is recognized as nonsense either by lowering the intracellular selenium concentration, which reduces the level of charged selenocysteyl-tRNA (Hat®eld et al., 1991), or by changing the Sec codon to nonsense (UAA) increases the ef®ciency of NMD; ...
... ef®ciency with which the selenocysteine (Sec) UGA codon is recognized as nonsense either by lowering the intracellular selenium concentration, which reduces the level of charged selenocysteyl-tRNA (Hat®eld et al., 1991), or by changing the Sec codon to nonsense (UAA) increases the ef®ciency of NMD; ...
Gene
![](https://commons.wikimedia.org/wiki/Special:FilePath/Gregor_Mendel.png?width=300)
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.