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Unit 1 science of chemistry
Unit 1 science of chemistry

... Compounds is a substance that contains two or more elements chemically combined in a fixed proportion. •Represented by chemical formulas using symbols of elements present in compound and subscripts indicated how many atoms of each element is present. Ex. H2O: water ...
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... Many live organisms – plants as well as animals – are capable of producing vitamin C themselves. The most important reactions occurring during this so-called biosynthesis of vitamin C, can be described schematically as in figure 1: ...
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... (b) A sample of oceanic water was found to contain 0·010 g of dissolved oxygen. Calculate the number of moles of dissolved oxygen present in the sample. ...
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... 6. Powdered magnesium carbonate is heated strongly. a. Why does this reaction state “strongly”? 7. An excess of nitric acid solution is added to a solution of tetraamminecopper(II) sulfate, Cu(NH3)42+. a. State the change in pH you would expect before and after this reaction. Explain. 8. Solid sodiu ...
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... Atoms are so small, it is difficult to discuss how much they weigh in grams  Use atomic mass units.  an atomic mass unit (amu) is one twelfth the mass of a carbon-12 atom  This gives us a basis for comparison  The decimal numbers on the table are atomic masses in amu ...
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... polyacrylonitrile fibers and a variety of plastics, is produced from gaseous  propylene, ammonia, and oxygen.  2 C3H6(g) + 2 NH3(g) + 3 O2(g)  2 C3H3N(g) + 6 H2O(g) (a) What mass of acrylonitrile can be produced from a mixture of 1.04 kg of  propylene, 1.55 kg of ammonia, and 2.21 kg of oxygen? ...
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... velocity. Besides, the date in Table 4 and Figure 5 shows that the conversion rate of fatty acid methyl ester was above 99% with the condition of less than 4.0h-1 space velocity. While in terms of purpose products, it was more than 90%, and increased slightly with space velocity increased. Compared ...
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... Group Roles: A Technician; B Leader; C Recorder Redox reactions are some of the most common and most useful chemical reactions. They produce electrical current which can be harnessed to do work. Transition metals play a very important role in redox chemistry. Questions: Which metals are easily oxidi ...
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... INTRODUCTION: Chemistry is a science that investigates changes in matter. Chemical reactions are the changes matter undergoes. The changes you can observe are called “macroscopic changes.” Often these changes, such as color changes, the formation of a solid (precipitation), or the formation of gas b ...
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... Unit 2: The Atom Place a checkmark next to each item that you can do. If a sample problem is given, complete it as evidence. Dalton’s Model: _____1. I can describe John Dalton’s contribution to our understanding of the atom. ...
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Bioorthogonal chemistry



The term bioorthogonal chemistry refers to any chemical reaction that can occur inside of living systems without interfering with native biochemical processes. The term was coined by Carolyn R. Bertozzi in 2003. Since its introduction, the concept of the bioorthogonal reaction has enabled the study of biomolecules such as glycans, proteins, and lipids in real time in living systems without cellular toxicity. A number of chemical ligation strategies have been developed that fulfill the requirements of bioorthogonality, including the 1,3-dipolar cycloaddition between azides and cyclooctynes (also termed copper-free click chemistry), between nitrones and cyclooctynes, oxime/hydrazone formation from aldehydes and ketones, the tetrazine ligation, the isocyanide-based click reaction, and most recently, the quadricyclane ligation.The use of bioorthogonal chemistry typically proceeds in two steps. First, a cellular substrate is modified with a bioorthogonal functional group (chemical reporter) and introduced to the cell; substrates include metabolites, enzyme inhibitors, etc. The chemical reporter must not alter the structure of the substrate dramatically to avoid affecting its bioactivity. Secondly, a probe containing the complementary functional group is introduced to react and label the substrate.Although effective bioorthogonal reactions such as copper-free click chemistry have been developed, development of new reactions continues to generate orthogonal methods for labeling to allow multiple methods of labeling to be used in the same biosystems.
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