Conformational dynamics of signaling proteins and ion channels
... Radiolytic footprinting and mass spectrometry were used to probe the structure of the inwardly rectifying potassium channel KirBac 3.1 in its closed and open states. By subjecting protein solutions to focused synchrotron X-ray beams with millisecond timescale exposures we modified solvent accessible ...
... Radiolytic footprinting and mass spectrometry were used to probe the structure of the inwardly rectifying potassium channel KirBac 3.1 in its closed and open states. By subjecting protein solutions to focused synchrotron X-ray beams with millisecond timescale exposures we modified solvent accessible ...
Lecture_11_2005
... • Overall goal - directly solve enough structures directly to be able to computationally model all future proteins. ...
... • Overall goal - directly solve enough structures directly to be able to computationally model all future proteins. ...
The Polarization Vector
... A: Recall that the direction of each dipole moment is the same as the polarizing electric field. Thus P ( r ) and E ( r ) have the same direction. There magnitudes are related by a unitless scalar value χe ( r ) , called electric susceptibility: ...
... A: Recall that the direction of each dipole moment is the same as the polarizing electric field. Thus P ( r ) and E ( r ) have the same direction. There magnitudes are related by a unitless scalar value χe ( r ) , called electric susceptibility: ...
Jones vector for horizontally polarized light The electric field
... Jones vector for linearly polarized light at an arbitrary angle y • The electric field oscillations make an angle with respect to the x-axis If = 0°, horizontally polarized If = 90°, vertically polarized ...
... Jones vector for linearly polarized light at an arbitrary angle y • The electric field oscillations make an angle with respect to the x-axis If = 0°, horizontally polarized If = 90°, vertically polarized ...
Macromolecules Notes File
... Splitting orange plant pigment yields a carotene and retinal molecule. ...
... Splitting orange plant pigment yields a carotene and retinal molecule. ...
Biological (organic) Molecules
... Lipids are highly useful storage molecules, can be broken down to release more energy than a sugar molecule ...
... Lipids are highly useful storage molecules, can be broken down to release more energy than a sugar molecule ...
Macromolecules -Large molecules formed by joining many subunits
... -Sequence of amino acids in the polypeptide chain -Many different sequences are possible with 20 AAs -Everything depends on this to fold right ...
... -Sequence of amino acids in the polypeptide chain -Many different sequences are possible with 20 AAs -Everything depends on this to fold right ...
Fluorine-Adding Bacteria May Transform Natural Product Medicines
... van der Waals interactions between particular amino acids in the protein and water-loving “polar” portions of the molecule. They also designed the binding pocket that grabs digoxigenin to be fairly rigid, which makes the protein more selective for the compound. The new work holds out hope that prote ...
... van der Waals interactions between particular amino acids in the protein and water-loving “polar” portions of the molecule. They also designed the binding pocket that grabs digoxigenin to be fairly rigid, which makes the protein more selective for the compound. The new work holds out hope that prote ...
SMALL MONOMER __________saccharide Simple Sugars EX
... _____________ is the principle element in the __________ molecules that organisms make and use ________________ compounds contain ______________ ___________________ compounds are all the other compounds Carbon has _____ valence electrons and can easily ________ with other _____________ to make large ...
... _____________ is the principle element in the __________ molecules that organisms make and use ________________ compounds contain ______________ ___________________ compounds are all the other compounds Carbon has _____ valence electrons and can easily ________ with other _____________ to make large ...
Protein Structure
... bonds are weak electrical attractions between positively and negatively charged atoms of different molecules. ...
... bonds are weak electrical attractions between positively and negatively charged atoms of different molecules. ...
View video content as a PDF
... Once the secondary structures of a protein have been folded, the model must be given the correct overall shape. When doing this it is very useful to refer back to the online visualization environment. This display can be edited to match what the final physical model should look like. The display sho ...
... Once the secondary structures of a protein have been folded, the model must be given the correct overall shape. When doing this it is very useful to refer back to the online visualization environment. This display can be edited to match what the final physical model should look like. The display sho ...
Power Point Presentation
... of radicals with one or more dangling bonds. Because the intermediates are in a vacuum, and because their position is controlled (as opposed to solutions, where the position and orientation of a molecule are largely random), such radicals will not react with the wrong thing for the very simple reaso ...
... of radicals with one or more dangling bonds. Because the intermediates are in a vacuum, and because their position is controlled (as opposed to solutions, where the position and orientation of a molecule are largely random), such radicals will not react with the wrong thing for the very simple reaso ...
Notes
... • Polymers (long chains) of AMINO ACIDS – arranged in specific sequence – linked by PEPTIDE BONDS – range in length from a few to 1000+ ...
... • Polymers (long chains) of AMINO ACIDS – arranged in specific sequence – linked by PEPTIDE BONDS – range in length from a few to 1000+ ...
Circular dichroism
Circular dichroism (CD) is dichroism involving circularly polarized light, i.e., the differential absorption of left- and right-handed light. Left-hand circular (LHC) and right-hand circular (RHC) polarized light represent two possible spin angular momentum states for a photon, and so circular dichroism is also referred to as dichroism for spin angular momentum. This phenomenon was discovered by Jean-Baptiste Biot, Augustin Fresnel, and Aimé Cotton in the first half of the 19th century. It is exhibited in the absorption bands of optically active chiral molecules. CD spectroscopy has a wide range of applications in many different fields. Most notably, UV CD is used to investigate the secondary structure of proteins. UV/Vis CD is used to investigate charge-transfer transitions. Near-infrared CD is used to investigate geometric and electronic structure by probing metal d→d transitions. Vibrational circular dichroism, which uses light from the infrared energy region, is used for structural studies of small organic molecules, and most recently proteins and DNA.