Tailoring Rydberg interactions via F\" orster resonances: state
... made to enhance sought-after properties is opened up. Even more tunability is given in experiments with a mix of different atomic species [39]. Furthermore, a strong dipole coupling results in a strong state mixture [40] and may be followed by state exchange betwen the atoms [41–45]. This process is ...
... made to enhance sought-after properties is opened up. Even more tunability is given in experiments with a mix of different atomic species [39]. Furthermore, a strong dipole coupling results in a strong state mixture [40] and may be followed by state exchange betwen the atoms [41–45]. This process is ...
Dietary Supplements and Military Divers
... tremendous source of up-to-date information on just about anything, is unregulated and unpoliced. It can be daunting, particularly for the layperson, unfamiliar with the tools to make such dif- ...
... tremendous source of up-to-date information on just about anything, is unregulated and unpoliced. It can be daunting, particularly for the layperson, unfamiliar with the tools to make such dif- ...
(1) Giycophorin was incorporated into large
... suits of these experiments are summarized in Table I. Comparison of the permeability data of the glycophorin-containing vesicles with the pure lipid vesicles, clearly shows that incorporation of glycophorin induces a largely increased permeability for glucose as well as for raffinose. This confirms ...
... suits of these experiments are summarized in Table I. Comparison of the permeability data of the glycophorin-containing vesicles with the pure lipid vesicles, clearly shows that incorporation of glycophorin induces a largely increased permeability for glucose as well as for raffinose. This confirms ...
Aminoacylated tmRNA from Escherichia coli interacts with
... two alanylated RNA minisubstrates are both protected against deacylation in the presence of EF-Tu-GTP (t1/2 5 114 min for minihelix Ala and t1/2 5 172 min for minihelix tmRNA ) albeit about twofold less than the fulllength RNAs (Table 1 and Fig+ 2D,E)+ This behavior is reminiscent of that observed w ...
... two alanylated RNA minisubstrates are both protected against deacylation in the presence of EF-Tu-GTP (t1/2 5 114 min for minihelix Ala and t1/2 5 172 min for minihelix tmRNA ) albeit about twofold less than the fulllength RNAs (Table 1 and Fig+ 2D,E)+ This behavior is reminiscent of that observed w ...
Producing the Ethylene Signal: Regulation and
... shown in blue, whereas negative regulators are shown in red. C-terminal motifs containing three Ser-Pro motifs phosphorylated by MAPKs (M) or a Target of ETO1 (TOE) interaction motif regulate turnover of type 1 and type 2 isozymes, respectively. The PP2C isoform AP2C1 negatively regulates MPK6 (Schw ...
... shown in blue, whereas negative regulators are shown in red. C-terminal motifs containing three Ser-Pro motifs phosphorylated by MAPKs (M) or a Target of ETO1 (TOE) interaction motif regulate turnover of type 1 and type 2 isozymes, respectively. The PP2C isoform AP2C1 negatively regulates MPK6 (Schw ...
ppt - Chair of Computational Biology
... limitation of Dayhoff-Matrix: the matrices based on the Dayhoff model of evolutionary rates are of limited value because the substitution rates were derived from sequence alignments of sequences that are more than 85% identical. ...
... limitation of Dayhoff-Matrix: the matrices based on the Dayhoff model of evolutionary rates are of limited value because the substitution rates were derived from sequence alignments of sequences that are more than 85% identical. ...
The Biochemical Machinery of Plastid Envelope
... the information present in their own genome but are strongly dependent on imported proteins that are encoded in the nuclear genome and translated in the cytoplasm. Plastids are present in every plant cell, with very few exceptions (such as the highly specialized male sexual cells), and their structu ...
... the information present in their own genome but are strongly dependent on imported proteins that are encoded in the nuclear genome and translated in the cytoplasm. Plastids are present in every plant cell, with very few exceptions (such as the highly specialized male sexual cells), and their structu ...
Cardiac mitochondrial matrix and respiratory complex - AJP
... attempt to characterize the sites with regard to the probability that they may influence function based on our understanding of the molecular mechanisms within the oxidative phosphorylation complexes. Since this exciting field is moving very quickly, we apologize in advance for any literature omissi ...
... attempt to characterize the sites with regard to the probability that they may influence function based on our understanding of the molecular mechanisms within the oxidative phosphorylation complexes. Since this exciting field is moving very quickly, we apologize in advance for any literature omissi ...
4. characterisation of novel proteins
... spatially and temporally active only in the developing seed. Data generated over three generations confirmed stability of the introduced genetic elements and indicated that the genes are inherited in a predicted manner according to Mendelian principles. Bioinformatic analysis of the insertion site a ...
... spatially and temporally active only in the developing seed. Data generated over three generations confirmed stability of the introduced genetic elements and indicated that the genes are inherited in a predicted manner according to Mendelian principles. Bioinformatic analysis of the insertion site a ...
Host Factors in the Replication of Positive
... recruitment of LC3 to form a complete autophagosome-like vesicle. Subsequently, viral RdRp and other components of viral RC are recruited to these vesicles for viral replication. Importantly, poliovirus may have evolved to block subsequent maturation and degradation of these autolysosomal-like membr ...
... recruitment of LC3 to form a complete autophagosome-like vesicle. Subsequently, viral RdRp and other components of viral RC are recruited to these vesicles for viral replication. Importantly, poliovirus may have evolved to block subsequent maturation and degradation of these autolysosomal-like membr ...
Coagulation
... The intrinsic pathway requires the clotting factors VIII, IX, X, XI, and XII. Also required are the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), as well as calcium ions and phospholipids secreted from platelets. The role of PK and HMWK is described in the above secti ...
... The intrinsic pathway requires the clotting factors VIII, IX, X, XI, and XII. Also required are the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), as well as calcium ions and phospholipids secreted from platelets. The role of PK and HMWK is described in the above secti ...
Document
... 2. Describe the secondary structure of DNA. Ans. Secondary structure of DNA is explained by Watson and Crick. According to Watson and Crick model DNA exists as a double helix. Two strands of polynucleotides are antiparallel. The back bone is formed by the sugar—phosphate-sugar chain. The nitrogen ba ...
... 2. Describe the secondary structure of DNA. Ans. Secondary structure of DNA is explained by Watson and Crick. According to Watson and Crick model DNA exists as a double helix. Two strands of polynucleotides are antiparallel. The back bone is formed by the sugar—phosphate-sugar chain. The nitrogen ba ...
Structure of L‑Serine Dehydratase from Legionella
... At least four types of Fe−S L-serine dehydratases that differ in their domain content and arrangement have been identified.17 They all contain a catalytic or α domain that harbors the binding site for the Fe−S cluster as well as a β domain whose function has not yet been completely defined. In the type ...
... At least four types of Fe−S L-serine dehydratases that differ in their domain content and arrangement have been identified.17 They all contain a catalytic or α domain that harbors the binding site for the Fe−S cluster as well as a β domain whose function has not yet been completely defined. In the type ...
IDENTIFICATION AND CHARACTERIZATION OF SYNAPTONEMAL
... without heterologous synapsis or synaptic adjustment, to form a complete set of entirely synapsed bivalents, have a better chance of producing viable meiotic products than cells which do not (e.g. De Boer and De Jong, 1989). According to this hypothesis mutation of genes encoding structural componen ...
... without heterologous synapsis or synaptic adjustment, to form a complete set of entirely synapsed bivalents, have a better chance of producing viable meiotic products than cells which do not (e.g. De Boer and De Jong, 1989). According to this hypothesis mutation of genes encoding structural componen ...
Regulation of intermediary metabolism by protein acetylation
... Box 1. More than 2000 proteins are acetylated in mammalian cells Owing to the technical difficulty of detection, an overwhelming proportion of the acetylation studies has been focused on histones and nuclear proteins [4,5]. Unlike phosphorylation, which can be readily detected by 32P-phosphate label ...
... Box 1. More than 2000 proteins are acetylated in mammalian cells Owing to the technical difficulty of detection, an overwhelming proportion of the acetylation studies has been focused on histones and nuclear proteins [4,5]. Unlike phosphorylation, which can be readily detected by 32P-phosphate label ...
Biotechnology and Bioengineering
... using primers F176-front and ToMO-SalI-rear (Table I). Similarly, to perform saturation mutagenesis at TouA position F196, a 763 bp DNA fragment was amplified using primers ToMO-KpnI-front and F196-rear, and a 898 bp DNA fragment was amplified using primers F196-front and ToMO-SalI-rear. The two deg ...
... using primers F176-front and ToMO-SalI-rear (Table I). Similarly, to perform saturation mutagenesis at TouA position F196, a 763 bp DNA fragment was amplified using primers ToMO-KpnI-front and F196-rear, and a 898 bp DNA fragment was amplified using primers F196-front and ToMO-SalI-rear. The two deg ...
ASMS 2004 de Novo
... • It is demonstrated that fragmentations of charged TMPP-Ac derivatives follow different pathways under low energy CID performed in a Q-TOF mass spectrometer. ...
... • It is demonstrated that fragmentations of charged TMPP-Ac derivatives follow different pathways under low energy CID performed in a Q-TOF mass spectrometer. ...
The Platform Protein Is Essential for Type IV Pilus
... present data that PilC may coordinate the activity of cytoplasmic polymerization (PilB) and depolymerization (PilT) ATPases via their interactions with its two cytoplasmic domains. Using in vitro co-affinity purification, we show that PilB interacts with the N-terminal cytoplasmic domain of PilC. We ...
... present data that PilC may coordinate the activity of cytoplasmic polymerization (PilB) and depolymerization (PilT) ATPases via their interactions with its two cytoplasmic domains. Using in vitro co-affinity purification, we show that PilB interacts with the N-terminal cytoplasmic domain of PilC. We ...
Adjeitey_Cyril _Nii-Klu_2013_ thesis
... that proton leaks through UCP1 could be a molecular target to combat certain forms of obesity. Although it is well established that UCP1 is regulated by allosteric mechanisms, alternative methods such as post-translational modification still remain to be explored. The aims of the present study were ...
... that proton leaks through UCP1 could be a molecular target to combat certain forms of obesity. Although it is well established that UCP1 is regulated by allosteric mechanisms, alternative methods such as post-translational modification still remain to be explored. The aims of the present study were ...
informed bodybuilding nutrition
... I have been working in the nutrition field for nearly 11 years, and qualified in 1995 from University of Surrey with an Honours degree in Nutrition with a State Registration in Dietetics (SRD). SRD is the only legally recognised qualification for nutrition in the UK, and is a licence to practice nut ...
... I have been working in the nutrition field for nearly 11 years, and qualified in 1995 from University of Surrey with an Honours degree in Nutrition with a State Registration in Dietetics (SRD). SRD is the only legally recognised qualification for nutrition in the UK, and is a licence to practice nut ...
The Plant Cell - Department of Biology
... KCBP mutant zwichel (zwi) have a short stalk and only one or two branches rather than the normal three or four (Hulskamp et al., 1994; Oppenheimer et al., 1997). Genetic studies with zwi indicate that KCBP is involved in a multiprotein complex important for trichome morphogenesis (Krishnakumar and O ...
... KCBP mutant zwichel (zwi) have a short stalk and only one or two branches rather than the normal three or four (Hulskamp et al., 1994; Oppenheimer et al., 1997). Genetic studies with zwi indicate that KCBP is involved in a multiprotein complex important for trichome morphogenesis (Krishnakumar and O ...
13- and 14-membered macrocyclic ligands containing
... linked to different biomolecules, such as monoclonal antibodies or peptides, have also been considered excellent candidates for therapy and are under investigation [16–24]. For therapeutic proposes in nuclear medicine, the radiotherapeutic agent should be stable in vivo in order to prevent their diss ...
... linked to different biomolecules, such as monoclonal antibodies or peptides, have also been considered excellent candidates for therapy and are under investigation [16–24]. For therapeutic proposes in nuclear medicine, the radiotherapeutic agent should be stable in vivo in order to prevent their diss ...
Homology Modelling and Structural Comparisons of Capsid
... elude the host immune system, and can be related to the publication from Kundu et al. [21], showing that viruses infecting the same population may have diverse biological fitness due to genetic mutations that translate into slight amino acid variation. Specifically, Cap must successfully evade the h ...
... elude the host immune system, and can be related to the publication from Kundu et al. [21], showing that viruses infecting the same population may have diverse biological fitness due to genetic mutations that translate into slight amino acid variation. Specifically, Cap must successfully evade the h ...
A new natural product-based hybrid
... frequently reported is the framework combination strategy. In this approach, two separate pharmacophores that inhibit different targets are synthetically linked or merged into a single molecule (7, 8). The major complexity that is involved in the design of multiple ligands lies in balancing both dru ...
... frequently reported is the framework combination strategy. In this approach, two separate pharmacophores that inhibit different targets are synthetically linked or merged into a single molecule (7, 8). The major complexity that is involved in the design of multiple ligands lies in balancing both dru ...
Protein–protein interaction
Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.