RNA Editing, ADAR1, and the Innate Immune Response
... remains to be specified for most of the editing sites, although functions for some edited non-coding RNA have been identified within microRNAs [25,26,36,37] or in recognition sequences on the 30 UTR of certain mRNAs [38]. Recent studies have also shown that editing on the 30 UTR of cathepsin S mRNA ...
... remains to be specified for most of the editing sites, although functions for some edited non-coding RNA have been identified within microRNAs [25,26,36,37] or in recognition sequences on the 30 UTR of certain mRNAs [38]. Recent studies have also shown that editing on the 30 UTR of cathepsin S mRNA ...
Gene Section ATF4 (activating transcription factor 4 (tax responsive enhancer element B67)) -
... (ODDD) motif which is recognized by the orthologs of C. elegans Egl-9, designated as PH (prolyl hydroxylase) domain containing enzymes (PHD) [also called HIF Prolyl Hydroxylase, HPH], specifically PHD3. The betaTrCP recognition motif is another degradation motif, which when phosphorylated, is recogn ...
... (ODDD) motif which is recognized by the orthologs of C. elegans Egl-9, designated as PH (prolyl hydroxylase) domain containing enzymes (PHD) [also called HIF Prolyl Hydroxylase, HPH], specifically PHD3. The betaTrCP recognition motif is another degradation motif, which when phosphorylated, is recogn ...
The virulence plasmids of Salmonella
... of the spvA promoter in a two-step fashion. Binding of SpvR to a promoter-distal regulatory sequence favors subsequent binding to a proximal region, which is essential to activate spvA transcription. Expression of spvR is self-regulated, and the structure of its promoter is similar to that of spvA. ...
... of the spvA promoter in a two-step fashion. Binding of SpvR to a promoter-distal regulatory sequence favors subsequent binding to a proximal region, which is essential to activate spvA transcription. Expression of spvR is self-regulated, and the structure of its promoter is similar to that of spvA. ...
Expression and function of decapentaplegic and thick veins during
... involves the coordinate activities of several signal transduction pathways, including those mediated by the transmembrane receptors Torpedo and Notch. In this report, the role of the signalling molecule Decapentaplegic during vein differentiation has been analysed. It is shown that decapentaplegic i ...
... involves the coordinate activities of several signal transduction pathways, including those mediated by the transmembrane receptors Torpedo and Notch. In this report, the role of the signalling molecule Decapentaplegic during vein differentiation has been analysed. It is shown that decapentaplegic i ...
PDF - Oxford Academic - Oxford University Press
... Background and Aims The arrangement of flowers in inflorescence shoots of Arabidopsis thaliana represents a regular spiral Fibonacci phyllotaxis. However, in the cuc2 cuc3 double mutant, flower pedicels are fused to the inflorescence stem, and phyllotaxis is aberrant in the mature shoot regions. T ...
... Background and Aims The arrangement of flowers in inflorescence shoots of Arabidopsis thaliana represents a regular spiral Fibonacci phyllotaxis. However, in the cuc2 cuc3 double mutant, flower pedicels are fused to the inflorescence stem, and phyllotaxis is aberrant in the mature shoot regions. T ...
Gbx2 is required for the morphogenesis of the mouse inner ear
... protein 68 kDa (NF68; Nef1 – Mouse Genome Informatics) and orthodenticle 2 (Otx2) were prepared as described (Morsli et al., 1999). RNA probes for Eya1 (Xu et al., 1997), Gata3 (Karis et al., 2001), Gbx2 (Bouillet et al., 1995), Myo15a (Anderson et al., 2000), Neurod1 (Ma et al., 1998) and Pax2 (Dre ...
... protein 68 kDa (NF68; Nef1 – Mouse Genome Informatics) and orthodenticle 2 (Otx2) were prepared as described (Morsli et al., 1999). RNA probes for Eya1 (Xu et al., 1997), Gata3 (Karis et al., 2001), Gbx2 (Bouillet et al., 1995), Myo15a (Anderson et al., 2000), Neurod1 (Ma et al., 1998) and Pax2 (Dre ...
The Homothorax homeoprotein activates the nuclear localization of
... Homeotic genes determine the identity of body segments in the anterior—posterior axis in Drosophila. These genes contain a DNA-binding domain, the homeodomain (HD), and act as transcriptional regulators. It was expected that different HD proteins bind to a different set of DNA targets to exert their ...
... Homeotic genes determine the identity of body segments in the anterior—posterior axis in Drosophila. These genes contain a DNA-binding domain, the homeodomain (HD), and act as transcriptional regulators. It was expected that different HD proteins bind to a different set of DNA targets to exert their ...
Signaling Pathways of Heme Oxygenase
... iron is cytotoxic by producing ROS via the Fenton reaction and needs to be contained by an iron-binding protein (Ponka, 1997). In accordance with this concept synthesis of the ironbinding protein ferritin has been demonstrated to be induced in coordination with HO-1 activity during the cellular stre ...
... iron is cytotoxic by producing ROS via the Fenton reaction and needs to be contained by an iron-binding protein (Ponka, 1997). In accordance with this concept synthesis of the ironbinding protein ferritin has been demonstrated to be induced in coordination with HO-1 activity during the cellular stre ...
Review of the p53 Tumor Suppressor Gene and its Role in Gliomas
... Association of Cancers with Characteristic Chromosomal And ...
... Association of Cancers with Characteristic Chromosomal And ...
Amber Extract
... cells. A statistical and biological pathway analysis of microarray data was performed. After 4 hours amber extract treatment, modulations in gene expression were observed for a set of 92 genes compared to ...
... cells. A statistical and biological pathway analysis of microarray data was performed. After 4 hours amber extract treatment, modulations in gene expression were observed for a set of 92 genes compared to ...
Gene Section MLL (myeloid/lymphoid or
... M5/M4 de novo and therapy related ANLL. Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated gene Variable breakpoints on both genes. Abnormal pro ...
... M5/M4 de novo and therapy related ANLL. Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated gene Variable breakpoints on both genes. Abnormal pro ...
Recruitment of CRABS CLAW to promote nectary development
... Nectaries are secretory organs that are widely present in flowering plants that function to attract floral pollinators. Owing to diversity in nectary positions and structures, they are thought to have originated multiple times during angiosperm evolution, with their potential contribution to the div ...
... Nectaries are secretory organs that are widely present in flowering plants that function to attract floral pollinators. Owing to diversity in nectary positions and structures, they are thought to have originated multiple times during angiosperm evolution, with their potential contribution to the div ...
13 MODIFIED TRUE/FALSE 1
... 1. One of the bases could be left out of the sequence. 2. An extra base could be added to the sequence. 3. One base could be substituted for another within the gene. ...
... 1. One of the bases could be left out of the sequence. 2. An extra base could be added to the sequence. 3. One base could be substituted for another within the gene. ...
Syntabulin, a motor protein linker, controls dorsal
... displays ventralization (Mei et al., 2009). Furthermore, a ubiquitin ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array formation and ventralization (Cuykendall and Houston, 2009). Cumul ...
... displays ventralization (Mei et al., 2009). Furthermore, a ubiquitin ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array formation and ventralization (Cuykendall and Houston, 2009). Cumul ...
genetics and cytogenetics
... ,/'In fixed and stained slides, the chromatm reticulum has the appearance of a network and is composed of numerous very long and extremely thin threads, in loose coils. These threads are the chromonemata. When the cell divides another substance, the matrix, condenses on these threads and the chromon ...
... ,/'In fixed and stained slides, the chromatm reticulum has the appearance of a network and is composed of numerous very long and extremely thin threads, in loose coils. These threads are the chromonemata. When the cell divides another substance, the matrix, condenses on these threads and the chromon ...
redundancy and regulatory interactions between two
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
A gain of function mutation causing skeletal overgrowth in the
... (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critical region. All five genes are located on the same strand. Marker positions are shown along with their number of crossovers from rapunzel (see Supplemental data for more details rega ...
... (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critical region. All five genes are located on the same strand. Marker positions are shown along with their number of crossovers from rapunzel (see Supplemental data for more details rega ...
The female-killing chromosome of the silkworm, Bombyx mori, was
... Figure 3. Amplification patterns of genomic DNA from females and males of the C137, p50, ZWII, and Z101 strains by using one set of primers, Maji-1B + Maji-2A. Lane M, molecular-size markers (100 bp ladder; Invitrogen). The number at the left indicate base pairs. The arrowhead indicates the Maji RAPD ...
... Figure 3. Amplification patterns of genomic DNA from females and males of the C137, p50, ZWII, and Z101 strains by using one set of primers, Maji-1B + Maji-2A. Lane M, molecular-size markers (100 bp ladder; Invitrogen). The number at the left indicate base pairs. The arrowhead indicates the Maji RAPD ...
CIRCADIAN RHYTHMS IN PLANTS C Robertson McClung
... of Arabidopsis peaks at dawn and dusk, respectively (162). We have defined a minimal CAT3 promoter sufficient to confer evening-specific circadian transcription (TP Michael & CR McClung, unpublished; see Figure 1). Evening-specific promoters have also been defined for the Arabidopsis genes encoding ...
... of Arabidopsis peaks at dawn and dusk, respectively (162). We have defined a minimal CAT3 promoter sufficient to confer evening-specific circadian transcription (TP Michael & CR McClung, unpublished; see Figure 1). Evening-specific promoters have also been defined for the Arabidopsis genes encoding ...
Lanosterol Biosynthesis in the Prokaryote
... is the subject of our recent work after identifying the first proven prokaryotic sterol biosynthetic gene/protein (Jackson et al. 2002). The importance of sterols in eukaryotes is well established because they modulate membrane fluidity and also serve as precursor molecules for hormone and brassinos ...
... is the subject of our recent work after identifying the first proven prokaryotic sterol biosynthetic gene/protein (Jackson et al. 2002). The importance of sterols in eukaryotes is well established because they modulate membrane fluidity and also serve as precursor molecules for hormone and brassinos ...
Disclosure All authors have no competing financial relationships to
... TLR7 in PBMCs, resulting in a trend of decreased downstream production of type I IFNs; whereas inhibition of miR-3148 has an opposite effect. ...
... TLR7 in PBMCs, resulting in a trend of decreased downstream production of type I IFNs; whereas inhibition of miR-3148 has an opposite effect. ...