Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... (AF15q14) • t(11;15)(q23;q14) → MLL - MPFYVE • t(11;15)(q23;q15) → MLL - AF15 • t(11;16)(q23;p13)/MDS, ANLL, t-ANLL, ALL → MLL - CREBBP (CBP) • t(11;17)(q23;p13)/t-ANLL → MLL - GAS7 • t(11;17)(q23;q21)/ANLL → MLL - ACACA • t(11;17)(q23;q21)/ANLL → MLL - LASP1 • t(11;17)(q23;q21)/ANLL → MLL - MLLT6 ( ...
... (AF15q14) • t(11;15)(q23;q14) → MLL - MPFYVE • t(11;15)(q23;q15) → MLL - AF15 • t(11;16)(q23;p13)/MDS, ANLL, t-ANLL, ALL → MLL - CREBBP (CBP) • t(11;17)(q23;p13)/t-ANLL → MLL - GAS7 • t(11;17)(q23;q21)/ANLL → MLL - ACACA • t(11;17)(q23;q21)/ANLL → MLL - LASP1 • t(11;17)(q23;q21)/ANLL → MLL - MLLT6 ( ...
Introns Structure Patterns of Variation in Nucleotide Composition in
... CDSs in a variety of eukaryotes (Comeron and Guthrie 2005; Parmley et al. 2007; Warnecke and Hurst 2007; Ke et al. 2008; Larracuente et al. 2008; Denisov et al. 2014; Falanga et al. 2014). Furthermore, variation in intron number, intron location, and/or intron length are recurrently reported as asso ...
... CDSs in a variety of eukaryotes (Comeron and Guthrie 2005; Parmley et al. 2007; Warnecke and Hurst 2007; Ke et al. 2008; Larracuente et al. 2008; Denisov et al. 2014; Falanga et al. 2014). Furthermore, variation in intron number, intron location, and/or intron length are recurrently reported as asso ...
Randa Elfadil Ibrahim abdalla
... Asthma is an inflammatory disease that results from interactions between multiple genetic and environmental factors that influence both its severity and its responsiveness to treatment. Haptoglobin (Hp) is an acute phase protein and functions as an immune system modulator. Recent studies have reveal ...
... Asthma is an inflammatory disease that results from interactions between multiple genetic and environmental factors that influence both its severity and its responsiveness to treatment. Haptoglobin (Hp) is an acute phase protein and functions as an immune system modulator. Recent studies have reveal ...
Mitotic Spindle Assembly by Two Different Pathways in Vitro
... was added to extracts on ice at a 1:10 dilution. In all cases sperm was added to extracts immediately before use; when mitotic extracts were activated into interphase, calcium and sperm nuclei were added simultaneously. In sperm mixing experiments, labeled and unlabeled nuclei were diluted together ...
... was added to extracts on ice at a 1:10 dilution. In all cases sperm was added to extracts immediately before use; when mitotic extracts were activated into interphase, calcium and sperm nuclei were added simultaneously. In sperm mixing experiments, labeled and unlabeled nuclei were diluted together ...
Mathematical Models of Cell Cycle Progression
... phases, which we further break up into model phases in order to capture certain features such as cells remaining in phases for a minimum amount of time. This results in a unique system of delay differential equations which are solved numerically using MATLAB. The model is also able to capture a uniqu ...
... phases, which we further break up into model phases in order to capture certain features such as cells remaining in phases for a minimum amount of time. This results in a unique system of delay differential equations which are solved numerically using MATLAB. The model is also able to capture a uniqu ...
Neisseria meningitidis: an overview of the carriage state
... morphism (PCR-RFLP) and sequencing of the genes encoding the PorA and PorB OMP, have been demonstrated to be more reliable than serological methods for typing of meningococcal strains (van der Ende et al., 2000; Zhu et al., 1995). PorA protein can be stable during chronic carriage of N. meningitidis ...
... morphism (PCR-RFLP) and sequencing of the genes encoding the PorA and PorB OMP, have been demonstrated to be more reliable than serological methods for typing of meningococcal strains (van der Ende et al., 2000; Zhu et al., 1995). PorA protein can be stable during chronic carriage of N. meningitidis ...
p53 in Hematologic Malignancies
... high levels of p53 protein, as determined by either immunoprecipitation or immunochemistry, buthaveno detectable p53 mutations are rarely found in patients with newly diagp53 m~tations.~"."' One study found that the protein in AML nosed T-ALL."" Interestingly, about 30% of samples from patients with ...
... high levels of p53 protein, as determined by either immunoprecipitation or immunochemistry, buthaveno detectable p53 mutations are rarely found in patients with newly diagp53 m~tations.~"."' One study found that the protein in AML nosed T-ALL."" Interestingly, about 30% of samples from patients with ...
Properties of Mitotic and Meiotic Recombination in the
... of these events shown in Table 1, for each strain, we allowed cells to form single colonies at 300 C. on rich growth medium (YPD). Each colony was suspended in water, and various dilutions were plated on SD complete, 5-FOA-containing medium, and HYG+CAN medium. Colonies formed on 5-FOA plates were r ...
... of these events shown in Table 1, for each strain, we allowed cells to form single colonies at 300 C. on rich growth medium (YPD). Each colony was suspended in water, and various dilutions were plated on SD complete, 5-FOA-containing medium, and HYG+CAN medium. Colonies formed on 5-FOA plates were r ...
Puffs and PCR: the in vivo dynamics of early gene
... de l’INSERM, Institut de Chimie Biologique, Faculté de Médecine, 11, rue Humann, 67085 Strasbourg Cédex, France *Author for correspondence ...
... de l’INSERM, Institut de Chimie Biologique, Faculté de Médecine, 11, rue Humann, 67085 Strasbourg Cédex, France *Author for correspondence ...
The role of Grainy head in epithelial tissue growth
... The grainy head (grh) gene family encodes an important group of transcription factors that play a remarkably conserved role in epithelial organ development, epithelial barrier formation and epithelial repair upon damage in different organisms. The regulation and molecular targets of Grh are numerous ...
... The grainy head (grh) gene family encodes an important group of transcription factors that play a remarkably conserved role in epithelial organ development, epithelial barrier formation and epithelial repair upon damage in different organisms. The regulation and molecular targets of Grh are numerous ...
Cell_Cycle_Module_Answers
... V25” = V25’ = 0.017, Vwee” = 5 (or larger). Stable steady state with MPF activity very low. b. By how much must Vwee” be raised to engage the checkpoint? 5 or larger c. To engage a checkpoint, is it sufficient for Chk1 to phosphorylate only Wee1 or only Cdc25? Maybe so, maybe not. In either of these ...
... V25” = V25’ = 0.017, Vwee” = 5 (or larger). Stable steady state with MPF activity very low. b. By how much must Vwee” be raised to engage the checkpoint? 5 or larger c. To engage a checkpoint, is it sufficient for Chk1 to phosphorylate only Wee1 or only Cdc25? Maybe so, maybe not. In either of these ...
oto`s role in head and trunk development
... induce the expression of forebrain markers in animal cap explants, whereas a posterior domain, expressing Xnot, is fated to form notochord and somites and induces the expression of both anterior and posterior markers. The small number of cells that the organizer contains and its dynamic nature make ...
... induce the expression of forebrain markers in animal cap explants, whereas a posterior domain, expressing Xnot, is fated to form notochord and somites and induces the expression of both anterior and posterior markers. The small number of cells that the organizer contains and its dynamic nature make ...
Slide 1
... During sexual reproduction, male and female reproductive cells join in a process known as fertilization to produce a new cell. Pea flowers are normally self-pollinating, which means that sperm cells fertilize egg cells from within the same flower. Mendel’s garden had several stocks of pea plants tha ...
... During sexual reproduction, male and female reproductive cells join in a process known as fertilization to produce a new cell. Pea flowers are normally self-pollinating, which means that sperm cells fertilize egg cells from within the same flower. Mendel’s garden had several stocks of pea plants tha ...
CCMG Guidelines: Prenatal and Postnatal Diagnostic Testing for
... Uniparental disomy (UPD) is defined as the inheritance or presence of both homologous chromosomes of a pair from one parent and no copy from the second parent in a diploid genome (Engel, 1980). UPD is classified as maternal or paternal, depending on the origin of the disomic chromosome. UPD can be f ...
... Uniparental disomy (UPD) is defined as the inheritance or presence of both homologous chromosomes of a pair from one parent and no copy from the second parent in a diploid genome (Engel, 1980). UPD is classified as maternal or paternal, depending on the origin of the disomic chromosome. UPD can be f ...
Risk assessment - Office of the Gene Technology Regulator
... 18 ha). The release may take place in the Queensland local government areas of Bundaberg, Caboolture and/or Cairns. The trial involves early stage ‘proof of concept’ research. The GM sugarcane lines containing only marker genes would be used to compare different genetic modification methods. The oth ...
... 18 ha). The release may take place in the Queensland local government areas of Bundaberg, Caboolture and/or Cairns. The trial involves early stage ‘proof of concept’ research. The GM sugarcane lines containing only marker genes would be used to compare different genetic modification methods. The oth ...
Foundations of Biology
... Pharming is the use of recombinant domestic animals to produce proteins and other bioactive compounds One of the most common strategies in pharming involves engineering mammals to produce desired proteins in their milk This strategy was first used to produce t-PA in the milk of goats It is not coinc ...
... Pharming is the use of recombinant domestic animals to produce proteins and other bioactive compounds One of the most common strategies in pharming involves engineering mammals to produce desired proteins in their milk This strategy was first used to produce t-PA in the milk of goats It is not coinc ...
Gregor Mendel was a 19th century priest and botanist who
... o Dunn (1965), under the assumption that Mendel studied one gene on each of the seven chromosomes, calculated the probability of doing so as 6/7 x 5/7 x 4/7 x 3/7 x 2/7 x 1/7 = 0.0061 (<1%), again calling Mendel's experimental results into question. Mendel studied: http://www.jic.bbsrc.ac.uk/germpla ...
... o Dunn (1965), under the assumption that Mendel studied one gene on each of the seven chromosomes, calculated the probability of doing so as 6/7 x 5/7 x 4/7 x 3/7 x 2/7 x 1/7 = 0.0061 (<1%), again calling Mendel's experimental results into question. Mendel studied: http://www.jic.bbsrc.ac.uk/germpla ...
Distalless and dachshund pattern both plesiomorphic
... for the spider C. salei (Prpic et al. 2008). After 3–4 days of development, a clutch of embryos was dechorionated in 50% bleach solution and arranged into 8 8 grids on an agar dish. Glass cover slips (22 22 mm), previously coated with “heptane glue” (made by dissolving double‐sided Scotch brand ...
... for the spider C. salei (Prpic et al. 2008). After 3–4 days of development, a clutch of embryos was dechorionated in 50% bleach solution and arranged into 8 8 grids on an agar dish. Glass cover slips (22 22 mm), previously coated with “heptane glue” (made by dissolving double‐sided Scotch brand ...
Molecular Network Controlling the Ovule Development in
... take place within the ovule. In the ovule both sporophytic and gametophytic generation coexist. The analyses of this developmental process provides an excellent tool to understand the molecular mechanism involved in controlling the basic processes like primordia initiation, specification, cell divis ...
... take place within the ovule. In the ovule both sporophytic and gametophytic generation coexist. The analyses of this developmental process provides an excellent tool to understand the molecular mechanism involved in controlling the basic processes like primordia initiation, specification, cell divis ...
Gene replacement with the human BRCA1 locus
... otherwise lethal phenotype observed in the homozygous Brca17/7 mice. We isolated human BRCA1 protein from these lines and found a correlation between expression level and rescue. Furthermore, the protein was correctly translated and stabilized following exposure to DNA damage. From these results, it ...
... otherwise lethal phenotype observed in the homozygous Brca17/7 mice. We isolated human BRCA1 protein from these lines and found a correlation between expression level and rescue. Furthermore, the protein was correctly translated and stabilized following exposure to DNA damage. From these results, it ...
Mouse Lefty2 and Zebrafish Antivin Are Feedback
... The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on chromosome 1 (Meno et al., 1997). To examine the role of lefty2 in gastrulation and L–R asymmetry, we generated mutant mice deficient in lefty2. To inactivate lefty2, we constructed a t ...
... The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on chromosome 1 (Meno et al., 1997). To examine the role of lefty2 in gastrulation and L–R asymmetry, we generated mutant mice deficient in lefty2. To inactivate lefty2, we constructed a t ...
Development of a repressible mycobacterial
... drug targets in bacteria. Moreover, they are required to characterize the function of essential genes, which cannot be deleted without obtaining a lethal phenotype. While many regulated promoters have been characterized in both Gram positive and Gram negative bacteria, only a few of them have been s ...
... drug targets in bacteria. Moreover, they are required to characterize the function of essential genes, which cannot be deleted without obtaining a lethal phenotype. While many regulated promoters have been characterized in both Gram positive and Gram negative bacteria, only a few of them have been s ...
Pollen developmental biology
... and microspore degeneration. In dex1, the tapetum appears normal, and a callose wall and primexine are present. Therefore it was concluded that primexine and the callose wall do not play a direct role in pattern formation, but the plasma membrane is likely to be important (Paxson-Sowders et al.1997 ...
... and microspore degeneration. In dex1, the tapetum appears normal, and a callose wall and primexine are present. Therefore it was concluded that primexine and the callose wall do not play a direct role in pattern formation, but the plasma membrane is likely to be important (Paxson-Sowders et al.1997 ...
Patterning Muscles Using Organizers: Larval Muscle
... are probably the surface blebbing described in early studies of the transformation of these muscles, and of similar muscles in other dipterans (for review see Crossley, 1978). Subsequently, at z15 h APF, each muscle fiber splits along its longitudinal axis, the dorsal-most muscle splitting last, res ...
... are probably the surface blebbing described in early studies of the transformation of these muscles, and of similar muscles in other dipterans (for review see Crossley, 1978). Subsequently, at z15 h APF, each muscle fiber splits along its longitudinal axis, the dorsal-most muscle splitting last, res ...