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ABSTRACT Title of Document: PROGRAMMED
ABSTRACT Title of Document: PROGRAMMED

... in the cell, but it certainly isn’t simple. After genes are transcribed into mRNAs, the ribosome is responsible for converting the information contained in nucleotide sequences to amino acids to form proteins. Ribosomes are thus essential to all forms of life. The ribosome is a complex machine made ...
Part
Part

... A plant in your garden avoids photorespiratory losses, has improved water use efficiency, shows high rates of photosynthesis at high temperatures and has improved efficiency of nitrogen utilisation. In which of the following physiological groups would you assign this plant? (1) Nitrogen fixer ...
Help Me Understand Genetics
Help Me Understand Genetics

... DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where ...
Fitness landscapes of gene regulation in variable - UvA-DARE
Fitness landscapes of gene regulation in variable - UvA-DARE

... with the optimal Pgal concentrations as obtained directly from the growth data in figure 6.1. Although the optimal level shows a very sharp Pgal dependence, this does not mean that the growth difference for optimal and non-optimal expression are necessarily large. We can see from the landscape in fig. ...
The Normal Uniform Differential Gene Expression
The Normal Uniform Differential Gene Expression

... expressed in two samples with one or more replicates. The probability of differential expression comes from modeling the normalized data with a two component mixture model; a uniform component for the differentially expressed genes and a normal component for the other genes (see Dean and Raftery (20 ...
Molecular cloning of a laccase isozyme gene from
Molecular cloning of a laccase isozyme gene from

... the absorbance spectrum of native laccase. All these copper ions appear to be involved in the catalytic mechanism. Amino acid sequence analysis of different laccases indicates that the copper-binding sites, involving ten-histidine residues, are very highly conserved. Various fungi, several insects ( ...
Gene Section EVI1 (ecotropic viral integration site 1 (EVI1) and
Gene Section EVI1 (ecotropic viral integration site 1 (EVI1) and

... Similar Evi1 expression patterns were also observed in Xenopus, chicken, and zebrafish. ...
inactivation of the odontogenic ameloblast
inactivation of the odontogenic ameloblast

... gingivectomy to induce its regeneration. Altogether, the results we have found replicate some of the structural changes seen during human periodontal disease and suggest that ODAM plays a role in maintaining periodontal integrity. Materials and Methods All experimental protocols and animal handling ...
Multiple genetic loci modify risk for retinoblastoma in
Multiple genetic loci modify risk for retinoblastoma in

... contribute to retinoblastoma formation in mice, because expression in the retina of the E7 oncogene from human papillomavirus (HPV) type 16 causes retinoblastoma only on a p53~/~ background.26 Human papillomavirus E6 and E7 oncoproteins belong to the same class of viral oncoproteins as does SV40 T-a ...
Forced Expression of Dystrophin Deletion Constructs Reveals
Forced Expression of Dystrophin Deletion Constructs Reveals

... Physiology and Biophysics,Howard Hughes Medical Institute, University of Iowa College of Medicine, Iowa City, Iowa 52242 ...
A Comparative Study on the Recovery of EcoRI Endonuclease from
A Comparative Study on the Recovery of EcoRI Endonuclease from

... preparation of recombinant molecules, and they provide an attractive system for the analysis of sequence specific DNA-protein interactions1 . Escherichia coli RI (EcoRI) endonuclease is a well-known restriction enzyme that recognizes the symmetrical hexanucleotide sequence GAATTC on duplex DNA and c ...
Role of two-component systems in the virulence of Streptococcus
Role of two-component systems in the virulence of Streptococcus

... membrane-associated sensor histidine kinase (HK) and a cytoplasmic cognate response regulator (RR). Upon receipt of a specific external stimulus the kinase domain of the HK sensor protein is activated to autophosphorylate a conserved histidine residue. HK proteins tend to be found as homodimers that ...
Functional Analysis of Maize RAD51 in Meiosis and
Functional Analysis of Maize RAD51 in Meiosis and

... gene: Zmrad51A1 and Zmrad51A2, which map to chromosomes 7 and 3, respectively (Franklin et al. 1999). These two genes are most closely related to AtRAD51 and only distantly related to AtRAD51 paralogs (AtRAD51B, AtRAD51C, AtRAD51D, AtXRCC2, and AtXRCC3; Bleuyard et al. 2005; Figure 1). Full-length c ...
Perrin 2012
Perrin 2012

... mating types are required to properly inform the zygote of its own ploidy level, and thereby switch on the correct developmental program: “[. . .] the signal for diploidy is often the production of a heterodimeric transcription factor encoded by, or under the direct regulation of, mating type loci. ...
Functional Diversiication within the Family of B
Functional Diversiication within the Family of B

... substantial amino acid conservation within the LLM domain (69.9%) as well as within the GATA DNA-binding domain (72.8%; Fig. 1A; Supplemental Fig. S2). By contrast, there was only very limited sequence conservation between the N termini or in the region between the GATA domain and the LLM domain (Fi ...
Genetic analysis of the floral initiation process (FLIP) in Arabidopsis
Genetic analysis of the floral initiation process (FLIP) in Arabidopsis

... Recent molecular and genetic analysis in both Arabidop sis and Antirrhinum majus have resulted in a model for the control of floral organ identity (Haughn and Somerville, 1988; Schwarz-Sommer et al., 1990; Bowman et al., 1991; Coen and Meyerowitz, 1991). The two basic tenets of the model are firstly ...
Alu
Alu

... [email protected] ...
Maintenance of genomic integrity by p53: complementary
Maintenance of genomic integrity by p53: complementary

... speculated whether p53 promoter DNA might assume di€erent conformational states, and whether p53 might be able to interact with such DNA. Using a variety of arti®cial DNA substrates displaying the same p53 target sequence in di€erent conformational states, we were able to demonstrate that p53 indeed ...
Comparative gene mapping in Arabidopsis lyrata chromosomes 6
Comparative gene mapping in Arabidopsis lyrata chromosomes 6

... them at intervals of about 1 Mbp, plus one gene from the region studied by Hagenblad & Nordborg (2002) ; two of these, At4g20410 and At4g22720, are located near the S-locus. To determine chromosome rearrangements near the centromere region on the short arm, we added genes close to the centromere, tw ...
Tandem Genetic Duplications in Phage and Bacteria
Tandem Genetic Duplications in Phage and Bacteria

... tion method should yield duplications that are the best indicators of the sizes and frequencies of spontaneous duplications. COINHERITANCE OF ALLELIC MARKERS A variety of detection schemes in­ volve genetic crosses that select for simultaneous inheritance of two alleles of a single locus. These alle ...


... occasion offers, to make several statements on this phase of the subject. I hold that heterosis is not a unitary phenomenon, but a complex series of phenomena for which no single cause or mechanism can be properly assumed to apply to all cases. The early hypothesis of DOCTOR EASTand myself that hete ...
Evolutionary dynamics of nematode operons
Evolutionary dynamics of nematode operons

... chance, trans-splicing gradually accumulates in the genome. Trans-splicing makes the origin of operons possible because it allows pre-mRNAs to escape exonucleolytic degradation (Blumenthal 2004). Subsequently, adjacent genes, regardless of their functional relationship, will form an operon by chance ...
Cross talk between the sporophyte and the
Cross talk between the sporophyte and the

... The importance of the integument to promote gametophyte formation is clearly exemplified by aintegumenta (ant) mutant (Fig. 1). The ANT gene encodes a putative transcription factor that shares homology with the floral homeotic gene APETALA2 (AP2) (Elliott et al. 1996; Jofuku et al. 1994; Klucher et ...
1 - Krishikosh
1 - Krishikosh

... are referred to as haploid cells (n). A genome is a set of chromosomes corresponding to the haploid set of a species. The number of chromosomes in each somatic cell is the same for all members of a given species. For example, human somatic cells contain 46 chromosomes, tobacco has 48, cattle 60, the ...
RNA Editing, ADAR1, and the Innate Immune Response
RNA Editing, ADAR1, and the Innate Immune Response

... remains to be specified for most of the editing sites, although functions for some edited non-coding RNA have been identified within microRNAs [25,26,36,37] or in recognition sequences on the 30 UTR of certain mRNAs [38]. Recent studies have also shown that editing on the 30 UTR of cathepsin S mRNA ...
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Polycomb Group Proteins and Cancer

The Polycomb-group proteins (PcGs) are a family of proteins that use epigenetic mechanisms to maintain or repress expression of their target genes. They were originally discovered in Drosophila (fruit flies), though they've been shown to be conserved in many species due to their vital roles in embryonic development. These proteins' ability to alter gene expression has made them targets of investigation for research groups seeking to understand disease pathology and oncology.
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