Regulation of Ovule Development
... phenotype: total loss of septum, placentas, and ovules (Figure 2B) (Liu et al., 2000). Although both of these genes are known to repress AGAMOUS (AG) genetically, this loss of the medial domain is not an effect of AG overexpression. Rather, ANT and LUG seem to share a vital role in promoting cell pr ...
... phenotype: total loss of septum, placentas, and ovules (Figure 2B) (Liu et al., 2000). Although both of these genes are known to repress AGAMOUS (AG) genetically, this loss of the medial domain is not an effect of AG overexpression. Rather, ANT and LUG seem to share a vital role in promoting cell pr ...
TP53 mutations as biomarkers for cancer epidemiology in Latin
... the existence of multiple ethnic groups, some of them affected by strong founder effects that may explain the local or regional clustering of relatively rare cancers. Thus, the use of molecular biomarkers may be particularly helpful to identify the respective roles of environmental, biological, life ...
... the existence of multiple ethnic groups, some of them affected by strong founder effects that may explain the local or regional clustering of relatively rare cancers. Thus, the use of molecular biomarkers may be particularly helpful to identify the respective roles of environmental, biological, life ...
7nQ Jj I f NO "7^07 - UNT Digital Library
... to understand. It offers a detailed look at all the components of genetics. It contains study questions as well as summaries for each chapter to provide an even better way to retain the knowledge from my lectures. The course that I have outlined is intended for a junior or senior college student. So ...
... to understand. It offers a detailed look at all the components of genetics. It contains study questions as well as summaries for each chapter to provide an even better way to retain the knowledge from my lectures. The course that I have outlined is intended for a junior or senior college student. So ...
Comparative Analysis Using DNA Microarrays: Sensitivity
... Analysis of DNA Microarray Data: Sensitivity, Specificity, and Other Real-World Issues ...
... Analysis of DNA Microarray Data: Sensitivity, Specificity, and Other Real-World Issues ...
lilliputian - Development - The Company of Biologists
... reorganization and interaction of the contractile actincytoskeleton with the newly forming plasma membranes of cellularizing embryos (Schweisguth et al., 1990; SimpsonRose and Wieschaus, 1992; Schejter and Wieschaus, 1993b; Hunter and Wieschaus, 2000). The nullo, Sry α, and bnk genes are expressed i ...
... reorganization and interaction of the contractile actincytoskeleton with the newly forming plasma membranes of cellularizing embryos (Schweisguth et al., 1990; SimpsonRose and Wieschaus, 1992; Schejter and Wieschaus, 1993b; Hunter and Wieschaus, 2000). The nullo, Sry α, and bnk genes are expressed i ...
Structure-Function Analysis of the Conserved Histone Chaperone
... Chromatin structure is crucial to regulate access to the genome for processes such as transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin struct ...
... Chromatin structure is crucial to regulate access to the genome for processes such as transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin struct ...
Identification of Genetic and Epigenetic Risk Factors for Psoriasis
... diseases, and seven additional regions that included chromosome 13q13 and 15q21. A follow-up study, aimed to identify potential functional SNPs in the PSORS1 region, implicated an allele-specific repressor role of SNP rs10456057 via binding to nuclear transcriptional factors. Further study with add ...
... diseases, and seven additional regions that included chromosome 13q13 and 15q21. A follow-up study, aimed to identify potential functional SNPs in the PSORS1 region, implicated an allele-specific repressor role of SNP rs10456057 via binding to nuclear transcriptional factors. Further study with add ...
8 VARIATION IN CHROMOSOME STRUCTURE AND NUMBER
... nonallelic homologous recombination because it has occurred at homologous sites (i.e., repetitive sequences), but the alleles of neighboring genes are not properly aligned. The result is that one chromatid has an internal duplication and another chromatid has a deletion. In Figure 8.5, the chromosom ...
... nonallelic homologous recombination because it has occurred at homologous sites (i.e., repetitive sequences), but the alleles of neighboring genes are not properly aligned. The result is that one chromatid has an internal duplication and another chromatid has a deletion. In Figure 8.5, the chromosom ...
From the Department of Zoology, University of
... contain the same fibrils, but they are differently arranged in space. This does, of course, not exclude chemical differences along their length. No doubt such differences are very important, one striking example being the loops and chromomeres in lampbrush chromosomes (8). Both structures consist of ...
... contain the same fibrils, but they are differently arranged in space. This does, of course, not exclude chemical differences along their length. No doubt such differences are very important, one striking example being the loops and chromomeres in lampbrush chromosomes (8). Both structures consist of ...
Characterization of chaperonin 10 (Cpn10)
... the E. histolytica gene encoding Cpn10 Searches of preliminary data generated by the E. histolytica genome project at the Sanger Institute revealed several clones with sequence similarity to the human Cpn10 protein sequence. PCR primers based on these clones, when used in PCR reactions on E. histoly ...
... the E. histolytica gene encoding Cpn10 Searches of preliminary data generated by the E. histolytica genome project at the Sanger Institute revealed several clones with sequence similarity to the human Cpn10 protein sequence. PCR primers based on these clones, when used in PCR reactions on E. histoly ...
The Role of Six1 in the Genesis of Muscle Cell and Skeletal Muscle
... between Six1 and Pax3 [9, 47]. Although great progress has been made in understanding the mechanisms underlying the genesis of muscle progenitors, more detail about these regulatory pathways remains to be identified. Pax3 plays a pivotal role in the delamination and migration of muscle progenitors a ...
... between Six1 and Pax3 [9, 47]. Although great progress has been made in understanding the mechanisms underlying the genesis of muscle progenitors, more detail about these regulatory pathways remains to be identified. Pax3 plays a pivotal role in the delamination and migration of muscle progenitors a ...
Jalasvuori_Vehicl
... certain corners had to be cut in various places in order to keep the text within realistic length. Furthermore, in an attempt to maintain the simplicity, the following nomenclature and definitions are used throughout this paper. A cell vehicle denotes a prokaryotic cell with membranes, resources, an ...
... certain corners had to be cut in various places in order to keep the text within realistic length. Furthermore, in an attempt to maintain the simplicity, the following nomenclature and definitions are used throughout this paper. A cell vehicle denotes a prokaryotic cell with membranes, resources, an ...
Gene Section DLX6 (distal-less homeobox 6) Atlas of Genetics and Cytogenetics
... genes characterized by a homeobox related to that found in the insect Distal-less (Dll) gene. The six DLX genes are organized as three bigenic pairs with a tail-to-tail orientation (Zerucha et al., 2000), and located on chromosomes where HOX clusters are also found (DLX5/DLX6; 7q21.3, syntenic to th ...
... genes characterized by a homeobox related to that found in the insect Distal-less (Dll) gene. The six DLX genes are organized as three bigenic pairs with a tail-to-tail orientation (Zerucha et al., 2000), and located on chromosomes where HOX clusters are also found (DLX5/DLX6; 7q21.3, syntenic to th ...
Meiosis
... made up of segments of DNA; that DNA is packaged into chromosomes • Each gene has a specific location (called a locus) on a certain chromosome ...
... made up of segments of DNA; that DNA is packaged into chromosomes • Each gene has a specific location (called a locus) on a certain chromosome ...
Efficiency of gene silencing in Arabidopsis
... and homologous inverted repeat (hIR) vectors. hIR constructs carry self-complementary intron-spliced fragments of the target gene whereas transitive vectors have the target sequence fragment adjacent to an intron-spliced, inverted repeat of heterologous origin. Both transitive and hIR constructs fac ...
... and homologous inverted repeat (hIR) vectors. hIR constructs carry self-complementary intron-spliced fragments of the target gene whereas transitive vectors have the target sequence fragment adjacent to an intron-spliced, inverted repeat of heterologous origin. Both transitive and hIR constructs fac ...
Real time PCR based determination of gene copy numbers in
... Nevertheless, recent studies reported even higher expression rates when the target gene was under the control of deletion variants of the AOX1 promoter [3] or in some cases also with the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter (PGAP) [4]. Depending on the target gene, high cop ...
... Nevertheless, recent studies reported even higher expression rates when the target gene was under the control of deletion variants of the AOX1 promoter [3] or in some cases also with the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter (PGAP) [4]. Depending on the target gene, high cop ...
A Study of Gene Linkage and Mapping Using Tetrad Analysis
... could use the same approach to develop detailed predictions for the linked model (with genes on opposite or on the same side of the centromere). All models presented here consider only single crossovers. The effect of multiple crossovers and the use of mapping functions and the Poisson distribution ...
... could use the same approach to develop detailed predictions for the linked model (with genes on opposite or on the same side of the centromere). All models presented here consider only single crossovers. The effect of multiple crossovers and the use of mapping functions and the Poisson distribution ...
A pair of Sox: distinct and overlapping functions of
... the splice-directed MOs caused sox9b transcript to accumulate in the nucleus rather than in the cytoplasm (Fig. 2D,E), suggesting that it remained in an unspliced form, as observed previously for sox9a (Yan et al., 2002), and confirming MO efficacy. ...
... the splice-directed MOs caused sox9b transcript to accumulate in the nucleus rather than in the cytoplasm (Fig. 2D,E), suggesting that it remained in an unspliced form, as observed previously for sox9a (Yan et al., 2002), and confirming MO efficacy. ...
Clamp loader structure predicts the architecture of DNA polymerase
... in the absence of ATP [13]. ATP binding to γ may separate δ′ from δ, allowing δ to bind β and open the ring. How do the above observations fit with the γ complex structure? The β interactive element site on the δ subunit is contained within the amino-terminal domain (see Figure 3a). The β interactiv ...
... in the absence of ATP [13]. ATP binding to γ may separate δ′ from δ, allowing δ to bind β and open the ring. How do the above observations fit with the γ complex structure? The β interactive element site on the δ subunit is contained within the amino-terminal domain (see Figure 3a). The β interactiv ...
New Construct Approaches for Efficient Gene Silencing in Plants
... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...
... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...
Complementary functions of the antiapoptotic protein A1 and serine
... overlapping pathways, which overcome the absence of STAT5. In accordance with this speculation, we observed that BCR/ABLtransformed cells were able to recover partially from expression of the STAT5B dominant-negative mutant,14 suggesting activation of redundant pathways. In conclusion, STAT5 seems t ...
... overlapping pathways, which overcome the absence of STAT5. In accordance with this speculation, we observed that BCR/ABLtransformed cells were able to recover partially from expression of the STAT5B dominant-negative mutant,14 suggesting activation of redundant pathways. In conclusion, STAT5 seems t ...
Ancestry of neuronal monoamine transporters in the Metazoa
... Fig.·1. Metazoan monoamine transporters belonging to the SLC6 family of membrane transporters have diagnostic polypeptide motifs. These conserved motifs helped identify three different monoamine transporter types, iDAT, a dopamine transporter restricted to invertebrates, and two widely distributed m ...
... Fig.·1. Metazoan monoamine transporters belonging to the SLC6 family of membrane transporters have diagnostic polypeptide motifs. These conserved motifs helped identify three different monoamine transporter types, iDAT, a dopamine transporter restricted to invertebrates, and two widely distributed m ...
Linear ubiquitin chains: enzymes, mechanisms and biology
... UBA–UBL complex as revealed in their crystal structure (figure 2) [28]. The UBL domain of HOIL-1L adopts the typical ubiquitin fold, whereas the UBA of HOIP forms a nine-helix bundle that includes a three-helix bundle consisting of a6, a7 and a8 that is similar to canonical UBA domains. Intriguingly ...
... UBA–UBL complex as revealed in their crystal structure (figure 2) [28]. The UBL domain of HOIL-1L adopts the typical ubiquitin fold, whereas the UBA of HOIP forms a nine-helix bundle that includes a three-helix bundle consisting of a6, a7 and a8 that is similar to canonical UBA domains. Intriguingly ...
Gene Section LMO2 (LIM domain only 2 (rhombotin-like 1))
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...