The TP53 Gene, Tobacco Exposure, and Lung Cancer
... having a high frequency (36%) compared to female never-smokers (11%) (Fig. 1) and the odds ratios were 6.77 (95% CI, 2.94–15.6, Po0.0001) for control 1 and 3.57 (95% CI, 1.61–7.94, P=0.001 ) for control 2. Similarly the GT:GA ratios between female smokers (1.5) and never-smokers (0.23) were highly d ...
... having a high frequency (36%) compared to female never-smokers (11%) (Fig. 1) and the odds ratios were 6.77 (95% CI, 2.94–15.6, Po0.0001) for control 1 and 3.57 (95% CI, 1.61–7.94, P=0.001 ) for control 2. Similarly the GT:GA ratios between female smokers (1.5) and never-smokers (0.23) were highly d ...
Symposium Poster - uospur
... Abstract: Defects in the development and formation of synapses can cause neuronal and synaptic overgrowth, which can lead to many neurological disorders including autism. Previous studies have shown that defective FMR1 and ADAR genes result in synaptic overgrowth in Drosophila neuromuscular junction ...
... Abstract: Defects in the development and formation of synapses can cause neuronal and synaptic overgrowth, which can lead to many neurological disorders including autism. Previous studies have shown that defective FMR1 and ADAR genes result in synaptic overgrowth in Drosophila neuromuscular junction ...
Phylogenetic ANOVA: The Expression Variance and
... analogy to test for drift via ratios of between- to within-population variance Lande (1979); ...
... analogy to test for drift via ratios of between- to within-population variance Lande (1979); ...
Reactome Functional Interaction (FI) Network
... Analysis Workflow – Cancer Microarray Experiment: Gene expression profiling of pancreatic tumour (vs normal tissue). Output: list of genes that show significant changes in expression. Downstream analysis: 1. Validation of the top genes sorted by fold-change (or p-value): artificial cut-off, informa ...
... Analysis Workflow – Cancer Microarray Experiment: Gene expression profiling of pancreatic tumour (vs normal tissue). Output: list of genes that show significant changes in expression. Downstream analysis: 1. Validation of the top genes sorted by fold-change (or p-value): artificial cut-off, informa ...
A Novel Mouse Chromosome 17 Hybrid Sterility Locus
... 1991). The genotypes of all hybrid mice used in this study are described by a notation which takes the following form: X. [Y/Z]. The first letter, outside the brackets, is indicative of the genetic background of the animal. Letters inside the brackets, separated by a "/," symbolize the chromosome I7 ...
... 1991). The genotypes of all hybrid mice used in this study are described by a notation which takes the following form: X. [Y/Z]. The first letter, outside the brackets, is indicative of the genetic background of the animal. Letters inside the brackets, separated by a "/," symbolize the chromosome I7 ...
Topic 13: Meiosis
... • In the beginning of telophase I, each half of the cell has a haploid set of chromosomes; each chromosome still consists of two sister chromatids • Cytokinesis usually occurs simultaneously, forming two haploid daughter cells • No chromosome replication occurs between the end of meiosis I and the b ...
... • In the beginning of telophase I, each half of the cell has a haploid set of chromosomes; each chromosome still consists of two sister chromatids • Cytokinesis usually occurs simultaneously, forming two haploid daughter cells • No chromosome replication occurs between the end of meiosis I and the b ...
RT-PCR Analysis - Shiu Lab - Michigan State University
... expression of these 23 PGs in a T87 suspension culture cell line that had been previously shown to have >60% genes expressed (24). Only one PG (At2g43860) was detected. To rule out the possibility of faulty primer designs, a second primer set was designed for each of these 23 PGs, but none led to d ...
... expression of these 23 PGs in a T87 suspension culture cell line that had been previously shown to have >60% genes expressed (24). Only one PG (At2g43860) was detected. To rule out the possibility of faulty primer designs, a second primer set was designed for each of these 23 PGs, but none led to d ...
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... These plants were “true-breeding,” meaning that they were selfpollinating, and would produce offspring identical to themselves. In other words, the traits of each successive generation would be the same. A trait is a specific characteristic, such as seed color or plant height, of an individual. Many ...
... These plants were “true-breeding,” meaning that they were selfpollinating, and would produce offspring identical to themselves. In other words, the traits of each successive generation would be the same. A trait is a specific characteristic, such as seed color or plant height, of an individual. Many ...
Biological interpretation of genome-wide association studies using
... that account for associations as well as the pathways and tissue/ cell type context(s) in which the genes’ actions affect phenotypes. Although cell-type-specific expression quantitative trait loci (eQTLs) or coding (non-synonymous) variants in strong LD with associated variants can potentially link t ...
... that account for associations as well as the pathways and tissue/ cell type context(s) in which the genes’ actions affect phenotypes. Although cell-type-specific expression quantitative trait loci (eQTLs) or coding (non-synonymous) variants in strong LD with associated variants can potentially link t ...
The msh2 Gene of Schizosaccharomyces pombe Is
... male mice are sterile. They show an arrest in meiosis I and abnormal chromosome synapsis, respectively (7, 16). For the fission yeast Schizosaccharomyces pombe, at least two pathways of mismatch repair have been postulated based on two lines of evidence. Marker effects of G-to-C transversions observ ...
... male mice are sterile. They show an arrest in meiosis I and abnormal chromosome synapsis, respectively (7, 16). For the fission yeast Schizosaccharomyces pombe, at least two pathways of mismatch repair have been postulated based on two lines of evidence. Marker effects of G-to-C transversions observ ...
Brooker Chapter 5 - Volunteer State Community College
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Abundance and distribution of Macrolide
... ARGs (Diehl and Lapara, 2010). However, the behaviors of ARGs during anaerobic wastewater treatment processes under high antibiotic levels have been seldom reported. Macrolides, which could inhibit a wide range of bacteria, are a group of antibiotics frequently used in clinics and feedlots (Iacoviel ...
... ARGs (Diehl and Lapara, 2010). However, the behaviors of ARGs during anaerobic wastewater treatment processes under high antibiotic levels have been seldom reported. Macrolides, which could inhibit a wide range of bacteria, are a group of antibiotics frequently used in clinics and feedlots (Iacoviel ...
Chapter 13
... one chromosome from each parent • The 46 chromosomes in a human somatic cell are two sets of 23: one from the mother and one from the father • A diploid cell (2n) has two sets of chromosomes • For humans, the diploid number is 46 (2n = 46) ...
... one chromosome from each parent • The 46 chromosomes in a human somatic cell are two sets of 23: one from the mother and one from the father • A diploid cell (2n) has two sets of chromosomes • For humans, the diploid number is 46 (2n = 46) ...
somatic hypermutation of the 5' noncoding region of the Frequent MARTINOrrI*t,
... NHL including 73% DLCL and 47% FL. Since this region was previously shown to be involved in chromosomal rearrangements in a smaller fraction of the same tumors (33% DLCL, 0% FL; Fig. 3), our findings indicate that the same domain of the BCL6 gene can be altered by different types of alterations. Mut ...
... NHL including 73% DLCL and 47% FL. Since this region was previously shown to be involved in chromosomal rearrangements in a smaller fraction of the same tumors (33% DLCL, 0% FL; Fig. 3), our findings indicate that the same domain of the BCL6 gene can be altered by different types of alterations. Mut ...
Restriction Fragment Length Polymorphism of hsp70
... animals, but a distinct 4.4-kb fragment was present only in BN and WKY strains. A shorter fragment of 3 kb, although also evident in WKY rats, was seen in all SHR strains of Prague, Taconic, and Charles River origin. Noticeably, in WKY rats, both bands were visible but the intensity of hybridization ...
... animals, but a distinct 4.4-kb fragment was present only in BN and WKY strains. A shorter fragment of 3 kb, although also evident in WKY rats, was seen in all SHR strains of Prague, Taconic, and Charles River origin. Noticeably, in WKY rats, both bands were visible but the intensity of hybridization ...
Molecular approaches for bacterial azoreductases
... acid sequence alignment and southern blot analysis enable finding azoreductase gene homologs in other bacterial stains. The selected azoreductase gene is amplified by PCR followed by restriction digestion. The gene sequence encoding the azoreductase is cloned into an appropriate expression vector in ...
... acid sequence alignment and southern blot analysis enable finding azoreductase gene homologs in other bacterial stains. The selected azoreductase gene is amplified by PCR followed by restriction digestion. The gene sequence encoding the azoreductase is cloned into an appropriate expression vector in ...
The novel Cer-like protein Caronte mediates the establishment of
... growth factor-b (TGF-b) family member, that has been proposed to act as a molecular midline barrier that would con®ne and prevent the `X' factor from diffusing from the left to the right side of the embryo12,13. Here we show that an excess of Lefty-1 in the left side of the embryo blocks activation ...
... growth factor-b (TGF-b) family member, that has been proposed to act as a molecular midline barrier that would con®ne and prevent the `X' factor from diffusing from the left to the right side of the embryo12,13. Here we show that an excess of Lefty-1 in the left side of the embryo blocks activation ...
Making Headway: The Roles of Hox Genes and Neural
... compartments called rhombomeres (r) (Fig. 1)[1]. Each rhombomere adopts a distinct set of molecular and cellular properties including restrictions in cell mixing and gives rise to unique regions of the mature adult brain[2,3,4,5,6,7,8,9]. The segmental organization of the hindbrain presages the esta ...
... compartments called rhombomeres (r) (Fig. 1)[1]. Each rhombomere adopts a distinct set of molecular and cellular properties including restrictions in cell mixing and gives rise to unique regions of the mature adult brain[2,3,4,5,6,7,8,9]. The segmental organization of the hindbrain presages the esta ...
Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter
... of CLA to dairy cows can have effects on the desaturase ratio. For this reason we were interested in the effect that CLA would have on activation of the bovine Scd gene promoter. Mac-T cells were transfected with a number of luciferase reporter vectors under the control of varying lengths of the Scd g ...
... of CLA to dairy cows can have effects on the desaturase ratio. For this reason we were interested in the effect that CLA would have on activation of the bovine Scd gene promoter. Mac-T cells were transfected with a number of luciferase reporter vectors under the control of varying lengths of the Scd g ...
Cross-talk between cell-cycle control and the environment
... The central regulators of the eukaryotic cell cycle are cyclin-dependent kinases (CDKs). They trigger not only mitosis and DNA replication but also have roles in many other cellular processes such as gene transcription, DNA repair and apoptosis. CDKs typically constitute a family of heterodimeric se ...
... The central regulators of the eukaryotic cell cycle are cyclin-dependent kinases (CDKs). They trigger not only mitosis and DNA replication but also have roles in many other cellular processes such as gene transcription, DNA repair and apoptosis. CDKs typically constitute a family of heterodimeric se ...
The Complete Chloroplast and Mitochondrial DNA Sequence of
... for land plants have a very conserved genome size, usually around 150 kb covering about 70–80 genes. In contrast, the cp genomes of green algae, although having a rather similar genome size between 150 and 200 kb, show a tremendous variation in gene content, due to massive gene loss, genome erosion, ...
... for land plants have a very conserved genome size, usually around 150 kb covering about 70–80 genes. In contrast, the cp genomes of green algae, although having a rather similar genome size between 150 and 200 kb, show a tremendous variation in gene content, due to massive gene loss, genome erosion, ...
TP53 mutations as biomarkers for cancer epidemiology in Latin
... the existence of multiple ethnic groups, some of them affected by strong founder effects that may explain the local or regional clustering of relatively rare cancers. Thus, the use of molecular biomarkers may be particularly helpful to identify the respective roles of environmental, biological, life ...
... the existence of multiple ethnic groups, some of them affected by strong founder effects that may explain the local or regional clustering of relatively rare cancers. Thus, the use of molecular biomarkers may be particularly helpful to identify the respective roles of environmental, biological, life ...
Structure, expression and chromosomal location of the Oct
... t 12 haplotype. A t w5 homozygous revertant ( t w5g unpublished) cosmid library was screened with the same Oct-4 probe to exclude trivial differences between the t- and wild-type sequences. A cosmid that mapped to chromosome 17 was identified using a B a m H I RFLP between t- (4.73 kb) and wild-type ...
... t 12 haplotype. A t w5 homozygous revertant ( t w5g unpublished) cosmid library was screened with the same Oct-4 probe to exclude trivial differences between the t- and wild-type sequences. A cosmid that mapped to chromosome 17 was identified using a B a m H I RFLP between t- (4.73 kb) and wild-type ...
Lecture 3
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...