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Summary of Some Ideas - NYU Computer Science Department
Summary of Some Ideas - NYU Computer Science Department

... by a transcriptional activator/factor, which attaches to a promoter (a specific sequence adjacent to the gene). • Regulatory sequences such as silencers and enhancers control the rate of transcription ...
Genetic Mosaics and the Germ Line Lineage
Genetic Mosaics and the Germ Line Lineage

... The cells that give rise to the germ line in humans are set aside early during embryogenesis [1]. The first cells that have been identified in humans as contributing to the germ line are progenitor germ cells (PGCs), which are distinguished by their specific cellular morphology and high-level expres ...
Hox, ParaHox, ProtoHox: facts and guesses
Hox, ParaHox, ProtoHox: facts and guesses

... duplication from an ancestral ‘central’ Hox gene until 1998, with the discovery of the ParaHox cluster (Brooke et al, 1998), an evolutionary sister complex of the Hox cluster. This finding indicated that a hypothetical ProtoHox cluster of four genes duplicated early in animal evolution, giving rise ...
VegT activates Bix4 to specify endodermal
VegT activates Bix4 to specify endodermal

... The three germ layers of the amphibian embryo are established by mechanisms involving both cytoplasmic localisation and cellcell interactions (Harland and Gerhart, 1997). The localisation of cytoplasmic determinants occurs during oogenesis, when various mRNAs and proteins become differentially distr ...
Pisum Genetics Volume 24 1992 Research Reports
Pisum Genetics Volume 24 1992 Research Reports

... branches were partitioned arbitrarily into a 15:1 ratio (Fr Fru, Fr fru, fr Fru low: fr fru high) by Lamprecht and a 9:7 ratio (Fr Fru low: Fr fru, fr Fru ,fr fru high) by Blixt. Both authors pointed out branching is a difficult trait for Mendelian analysis since expression is very subject to enviro ...
Journal of Bacteriology
Journal of Bacteriology

... The light intensity at the table surface was approximately 20,000 lx (Philips TLF 60W/33 fluorescent tubes), and the day length was 16 h. The roots were not shielded from light, and no forced aeration was applied (41). Prior to cocultivation, bacteria were grown at 28°C on solid YMB medium (26) for ...
Cloning and Expression of Cellulosimicrobium cellulans β
Cloning and Expression of Cellulosimicrobium cellulans β

... gene band on agarose gel as well as 1.9 kbp DNA encoding β-1,3-glucanase gene insert amplified on the recombinant vector via PCR indicated the integration of the gene into the plasmid. Recombinant L. plantarum colonies with pTE353-βG on MRS-laminarin-agar plate showed clear positive zones by Congo-r ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
Protocol: Genome-scale CRISPR-Cas9 Knockout

... Programmable nucleases have emerged as a promising new genetic perturbation technology capable of precisely recognizing and cleaving target DNA17-19. Particularly, the RNA-guided endonuclease Cas9 from the microbial immune system CRISPR (clustered regularly interspaced short palindromic repeat) has ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
Protocol: Genome-scale CRISPR-Cas9 Knockout

... Programmable nucleases have emerged as a promising new genetic perturbation technology capable of precisely recognizing and cleaving target DNA17-19. Particularly, the RNA-guided endonuclease Cas9 from the microbial immune system CRISPR (clustered regularly interspaced short palindromic repeat) has ...
Hox patterning of the vertebrate rib cage
Hox patterning of the vertebrate rib cage

... reported defects in these mutants also show no clear colinearity. The phenotypes in these animals are reported to localize at both cervicothoracic and at thoracolumbar transition points, not to distinct AP regions of the axial skeleton. These combined results suggest that there are alternative mecha ...
Mycoplasma genitalium: a brief review
Mycoplasma genitalium: a brief review

Hox patterning of the vertebrate rib cage
Hox patterning of the vertebrate rib cage

... reported defects in these mutants also show no clear colinearity. The phenotypes in these animals are reported to localize at both cervicothoracic and at thoracolumbar transition points, not to distinct AP regions of the axial skeleton. These combined results suggest that there are alternative mecha ...
2004-2005
2004-2005

... The current research activities of the Division of Epidemiology and Prevention cover the following four subjects: 1) descriptive epidemiology of cancer incidence and mortality, with special reference to improvement of the Aichi Prefectural Cancer Registry; 2) analytical epidemiology based on the hos ...
Cell Membrane - Swampscott Middle School
Cell Membrane - Swampscott Middle School

... are needed to see this picture. Quic kTime™ and a ...
Leukaemia Section MLL amplification in leukemia  Atlas of Genetics and Cytogenetics
Leukaemia Section MLL amplification in leukemia Atlas of Genetics and Cytogenetics

... rearrangement of this gene. RNA overexpression is the result of the increase copy number of MLL (gain of function). Moreover, the amplified region is not limited to the MLL/11q23.3 gene locus, and other genes in the MLL flanking region have been also amplified. FISH and other molecular techniques ha ...
File - interACT - American College of Toxicology
File - interACT - American College of Toxicology

... Zhejiang University in Hangzhou, China, and received her Ph.D. Degree with honors in University of Kansas Medical Center. Julia currently is an Assistant Professor in Toxicology in the Department of Environmental and Occupational Health Sciences. She is a recipient of the Sheldon D. Murphy Endowed C ...
Engrailed cooperates with extradenticle and homothorax to repress
Engrailed cooperates with extradenticle and homothorax to repress

... Fig. 1F-H, complete removal of both maternal and zygotic exd function caused a dramatic drop in En repression activity on the slp gene. However, as with hth, there appeared to be residual activity even in the absence of exd function. Thus, although En retains a residual repression activity in vivo w ...
An Introduction to Streptomyces
An Introduction to Streptomyces

Conservation and diversification of gene function during mouthpart
Conservation and diversification of gene function during mouthpart

... The functions of the leg gap genes hth, dac, and Dll have been investigated in great detail during Drosophila leg development. Here, hth, dac, and Dll are expressed in antagonistic domains, which help establish the proximal– distal axis of the adult leg (reviewed in Kojima 2004). Specifically, the co ...
PDF - Journal of Genomics
PDF - Journal of Genomics

... Journal of Genomics 2015, Vol. 3 Buchnera with nutrients, including nonessential amino acids and carbohydrates that are abundant in their phloem-based diet or produced by the host. Genomic evidence suggests that several amino acid biosynthetic pathways are shared between aphid and Buchnera, providi ...
Chpt12_RNAProcessing.doc
Chpt12_RNAProcessing.doc

... over-expression or ectopic expression of a defined gene were the cause of some pathology (e.g. some form of cancer), then reducing its expression could have therapeutic value. Other RNAs possibly involved in catalysis, such as the snRNAs involved in splicing pre-mRNA (discussed in the next section). ...
PowerPoint Presentation - Meiosis
PowerPoint Presentation - Meiosis

... • Intimate contact provides route for infection by parasites (AIDS, syphillis, etc.) • Genetic costs: in sex, we pass on only half of genes to offspring. • Males are an expensive luxury - in most species they contribute little to rearing offspring. ...
Meiosis - TeacherWeb
Meiosis - TeacherWeb

... • Intimate contact provides route for infection by parasites (AIDS, syphillis, etc.) • Genetic costs: in sex, we pass on only half of genes to offspring. • Males - in most species they contribute little to rearing offspring. ...
Bio-session package - Social Science Genetic Association Consortium
Bio-session package - Social Science Genetic Association Consortium

... with SNPs that are genotyped on ‘‘SNP chips.’’ Because there are many more segregating variants in the population than those genotyped in GWASs, it is unlikely, but not impossible, that a mutation is genotyped itself, and so its effect usually will be detected through an association with a genotyped ...
Inferring Host Gene Subnetworks Involved in Viral
Inferring Host Gene Subnetworks Involved in Viral

... a variety of host intracellular interactions. The output is an ensemble of subnetworks that provides a consistent explanation for the measured phenotypes, predicts which unassayed host factors modulate the virus, and predicts which host factors are the most direct interfaces with the virus. We infer ...
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Polycomb Group Proteins and Cancer

The Polycomb-group proteins (PcGs) are a family of proteins that use epigenetic mechanisms to maintain or repress expression of their target genes. They were originally discovered in Drosophila (fruit flies), though they've been shown to be conserved in many species due to their vital roles in embryonic development. These proteins' ability to alter gene expression has made them targets of investigation for research groups seeking to understand disease pathology and oncology.
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