The X Chromosome in Quantitative Trait Locus Mapping
... In tackling the problem of how to assign a LOD threshold for the X chromosome, then, one might choose to ensure that the power to detect a QTL on the X chromosome is the same as that for the autosomes. This is tricky, however, in that the nature of the effect of an X chromosome QTL can be markedly d ...
... In tackling the problem of how to assign a LOD threshold for the X chromosome, then, one might choose to ensure that the power to detect a QTL on the X chromosome is the same as that for the autosomes. This is tricky, however, in that the nature of the effect of an X chromosome QTL can be markedly d ...
outline4003
... Characterized by stromal haze, and milky white opacities (glucosamineglycans) Progresses to corneal periphery by ages 20-30 By age 40, PK may be required Mutation localized to the 123 gene on chromosome 16 (16q22) Central Crystalline Dystrophy of Schnyder Characterized by central crystalline stromal ...
... Characterized by stromal haze, and milky white opacities (glucosamineglycans) Progresses to corneal periphery by ages 20-30 By age 40, PK may be required Mutation localized to the 123 gene on chromosome 16 (16q22) Central Crystalline Dystrophy of Schnyder Characterized by central crystalline stromal ...
Female Male Human chromosomal abnormalities may be numerical
... In women, however, only one gamete is produced from each meiosis. The other three haploid equivalents are discarded in structures called the first and second polar bodies. ...
... In women, however, only one gamete is produced from each meiosis. The other three haploid equivalents are discarded in structures called the first and second polar bodies. ...
Tetraploid rescue - Development
... examination revealed a high frequency of a distinct class of abnormal embryos. They were apparently normal by their gross morphology, but the embryonic ectoderm layer was disintegrated into single cells which were scattered throughout the embryonic region (Fig. 2C). The embryonic visceral endoderm l ...
... examination revealed a high frequency of a distinct class of abnormal embryos. They were apparently normal by their gross morphology, but the embryonic ectoderm layer was disintegrated into single cells which were scattered throughout the embryonic region (Fig. 2C). The embryonic visceral endoderm l ...
1 Direct evidence that genetic variation in glycerol-3
... fermentation products including alcohols. In particular, it is believed that the high tolerance of D. melanogaster to alcohols is an evolved phenotype because other members of the melanogaster subgroup, such as D. simulans, show lower tolerance and avoid alcohol exposure (Mckenzie and Parsons 1972; ...
... fermentation products including alcohols. In particular, it is believed that the high tolerance of D. melanogaster to alcohols is an evolved phenotype because other members of the melanogaster subgroup, such as D. simulans, show lower tolerance and avoid alcohol exposure (Mckenzie and Parsons 1972; ...
LAZY1 controls rice shoot gravitropism through
... In Arabidopsis, root cap and shoot endodermis are responsible for sensing gravity in plant roots and shoots, respectively [5, 6]. The displacement of amyloplasts is thought to be the main event that triggers further signal transduction. Phytohormones [7-10], cytosolic ions such as Ca2+ [11, 12], pH ...
... In Arabidopsis, root cap and shoot endodermis are responsible for sensing gravity in plant roots and shoots, respectively [5, 6]. The displacement of amyloplasts is thought to be the main event that triggers further signal transduction. Phytohormones [7-10], cytosolic ions such as Ca2+ [11, 12], pH ...
Genes and Genetic Testing in Hereditary Ataxias
... have an underlying genetic cause. Hereditary ataxias are a group of highly heterogeneous diseases, but each usually follows a typical Mendelian dominant, recessive, or X-linked inheritance. The prevalence of hereditary ataxias varies by population and has been estimated at 1–9 per 100,000 people [1– ...
... have an underlying genetic cause. Hereditary ataxias are a group of highly heterogeneous diseases, but each usually follows a typical Mendelian dominant, recessive, or X-linked inheritance. The prevalence of hereditary ataxias varies by population and has been estimated at 1–9 per 100,000 people [1– ...
UB_GO_Apr_2004 - Buffalo Ontology Site
... continuants (= they endure through time while undergoing changes of various sorts) ...
... continuants (= they endure through time while undergoing changes of various sorts) ...
Genetic crosses - thephysicsteacher.ie
... Chromosomes: Thread-like structures, that occur in the nuclei of living cells, which are made of DNA and protein and contain genes. DNA: Deoxyribonucleic acid - transmits hereditary information and controls cellular activities. Locus: The position of a gene on a chromosome (‘its address’). Homologou ...
... Chromosomes: Thread-like structures, that occur in the nuclei of living cells, which are made of DNA and protein and contain genes. DNA: Deoxyribonucleic acid - transmits hereditary information and controls cellular activities. Locus: The position of a gene on a chromosome (‘its address’). Homologou ...
Meiosis - Myersbiology
... • Intimate contact provides route for infection by parasites (AIDS, syphillis, etc.) • Genetic costs: in sex, we pass on only half of genes to offspring. • Males are an expensive luxury - in most species they contribute little to rearing offspring. ...
... • Intimate contact provides route for infection by parasites (AIDS, syphillis, etc.) • Genetic costs: in sex, we pass on only half of genes to offspring. • Males are an expensive luxury - in most species they contribute little to rearing offspring. ...
High grade B-cell lymphomas (HGBL): Altered terminology in the
... Retain morphologic variants but not needed in the diagnosis, add the “blastoid” variant Avoid misinterpreting focal follicular involvement by DLBCL as a FL component Deal with double expressor (MYC, BCL2) as a prognostic indicator, not as a specific subtype, which is also not a surrogate for looking ...
... Retain morphologic variants but not needed in the diagnosis, add the “blastoid” variant Avoid misinterpreting focal follicular involvement by DLBCL as a FL component Deal with double expressor (MYC, BCL2) as a prognostic indicator, not as a specific subtype, which is also not a surrogate for looking ...
bacterial plasmids - Acta Medica Medianae
... with potential recipient cell and his retraction leads to close connection between cell membranes of a donor and a recipient. It is supposed that a small canal, formed in this way, allows DNA transfer, or through the pilus itself, which is wide enough to enable passing of single chain DNA, or we hav ...
... with potential recipient cell and his retraction leads to close connection between cell membranes of a donor and a recipient. It is supposed that a small canal, formed in this way, allows DNA transfer, or through the pilus itself, which is wide enough to enable passing of single chain DNA, or we hav ...
BMC Developmental Biology
... somites and for the maintenance of caudal somite identity, respectively. The rostro-caudal polarity of somites is initiated early on within the presomitic mesoderm in nascent somites. Here we have investigated the requirement of restricted Dll1 expression in caudal somite compartments for the mainte ...
... somites and for the maintenance of caudal somite identity, respectively. The rostro-caudal polarity of somites is initiated early on within the presomitic mesoderm in nascent somites. Here we have investigated the requirement of restricted Dll1 expression in caudal somite compartments for the mainte ...
Selective Crossover in Genetic Algorithms: An Empirical Study
... his theory of the gene as the fundamental unit of natural selection. Chromosomes ...
... his theory of the gene as the fundamental unit of natural selection. Chromosomes ...
Chapter 3 Clustering Microarray Data
... k=1 ρik > 0; ejk is the jth element of the kth eigenvector, and ǫij ∼ N(0, σ ) is the error. Gene shaving clusters usually cover a small proportion of the data and as they are found independently, may overlap, giving the structure of Figure 3.1(c). In addition, correlation can be positive or negativ ...
... k=1 ρik > 0; ejk is the jth element of the kth eigenvector, and ǫij ∼ N(0, σ ) is the error. Gene shaving clusters usually cover a small proportion of the data and as they are found independently, may overlap, giving the structure of Figure 3.1(c). In addition, correlation can be positive or negativ ...
Splicing regulation: a structural biology perspective
... Recognizing pyrimidine-tract by Sex-lethal, U2AF65 and PTB The 3’ splice-site pyrimidine-tract is a major cis-acting element for both constitutive and alternative splicing. Several trans-acting factors have been shown to bind the pyrimidinetract resulting in activating (U2AF65) or repressing (Sex-l ...
... Recognizing pyrimidine-tract by Sex-lethal, U2AF65 and PTB The 3’ splice-site pyrimidine-tract is a major cis-acting element for both constitutive and alternative splicing. Several trans-acting factors have been shown to bind the pyrimidinetract resulting in activating (U2AF65) or repressing (Sex-l ...
PDF
... congenital malformations, including polydactyly and facial clefting. Although phenotypically similar to talpid3, talpid2 has a distinct facial phenotype and an unknown cellular, molecular and genetic basis. We set out to determine the etiology of the craniofacial phenotype of this mutant. We confirm ...
... congenital malformations, including polydactyly and facial clefting. Although phenotypically similar to talpid3, talpid2 has a distinct facial phenotype and an unknown cellular, molecular and genetic basis. We set out to determine the etiology of the craniofacial phenotype of this mutant. We confirm ...
The Zn Finger protein Iguana impacts Hedgehog signaling by
... the animals between five and seven days following RNAi, and reached a low point following approximately 14 days of RNAi (Fig. 2B). During the period of cilia loss, remaining cilia maintained normal length (Fig. 2B) and were capable of beating (Supplementary movies 3, 4). These data indicate a requi ...
... the animals between five and seven days following RNAi, and reached a low point following approximately 14 days of RNAi (Fig. 2B). During the period of cilia loss, remaining cilia maintained normal length (Fig. 2B) and were capable of beating (Supplementary movies 3, 4). These data indicate a requi ...
... Saccharomyces kudriavzevii was described. These strains exhibit physiological properties of potential biotechnological interest. A preliminary characterization of these hybrids showed a trend to reduce the S. kudriavzevii fraction of the hybrid genome. We characterized the genomic constitution of se ...
Are Incomplete Denitrification Pathways a Common Trait in Thermus
... designed custom primers for polymerase chain reaction (PCR) amplification of denitrification genes including narG, nirS, nirK, and norB to screen for the genetic capacity for each step in denitrification. Experimental results show that all Thermus strains tested display incomplete denitrification pa ...
... designed custom primers for polymerase chain reaction (PCR) amplification of denitrification genes including narG, nirS, nirK, and norB to screen for the genetic capacity for each step in denitrification. Experimental results show that all Thermus strains tested display incomplete denitrification pa ...
Supplementary Legends - Word file
... cytokinesis. Sister-chromatid separation defect – regression of the furrow. Several gene knockouts lead to a defect in spindle midzone formation and sister chromatid separation. These mutant embryos specify and ingress a furrow but do not complete cytokinesis. Most of the genes with this phenotype b ...
... cytokinesis. Sister-chromatid separation defect – regression of the furrow. Several gene knockouts lead to a defect in spindle midzone formation and sister chromatid separation. These mutant embryos specify and ingress a furrow but do not complete cytokinesis. Most of the genes with this phenotype b ...
Effete, a Drosophila chromatin-associated ubiquitin
... DNA replication and shield chromosome ends from inappropriate DNA repair, which might result in end-to-end fusion (Palm and De Lange 2008; Jain and Cooper 2010; Raffa et al. 2011). In most organisms, telomeres terminate with tandemly repeated of G-rich sequences, which are added to chromosome ends b ...
... DNA replication and shield chromosome ends from inappropriate DNA repair, which might result in end-to-end fusion (Palm and De Lange 2008; Jain and Cooper 2010; Raffa et al. 2011). In most organisms, telomeres terminate with tandemly repeated of G-rich sequences, which are added to chromosome ends b ...
Etiology : cytogenetics and microdeletions - HAL
... Deletions were found in the 21qter and 14q loci, which are previously annotated in the literature [Kamnasaran and others 2005; Roessler and others 1999], reinforcing their potential involvement in HPE. Several new candidate loci not suspected to be involved in the disease at that time were also iden ...
... Deletions were found in the 21qter and 14q loci, which are previously annotated in the literature [Kamnasaran and others 2005; Roessler and others 1999], reinforcing their potential involvement in HPE. Several new candidate loci not suspected to be involved in the disease at that time were also iden ...
mic.sgmjournals.org
... Corynebacterium glutamicum is a biotin-auxotrophic bacterium and some strains efficiently produce glutamic acid under biotin-limiting conditions. In an effort to understand C. glutamicum metabolism under biotin limitation, growth of the type strain ATCC 13032 was investigated in batch cultures and a ...
... Corynebacterium glutamicum is a biotin-auxotrophic bacterium and some strains efficiently produce glutamic acid under biotin-limiting conditions. In an effort to understand C. glutamicum metabolism under biotin limitation, growth of the type strain ATCC 13032 was investigated in batch cultures and a ...
Engineered bacteriophage-defence systems in bioprocessing
... genetic content and genomic organization of these seven phages exhibit significant similarities to other members of the λ-superfamily of phages23. Bioinformatic analyses have provided significant insight into the evolution of S. thermophilus phages, revealing that their genomes are molecular mosaics ...
... genetic content and genomic organization of these seven phages exhibit significant similarities to other members of the λ-superfamily of phages23. Bioinformatic analyses have provided significant insight into the evolution of S. thermophilus phages, revealing that their genomes are molecular mosaics ...