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Functional consequences of the human DMT1 (SLC11A2) mutation
Functional consequences of the human DMT1 (SLC11A2) mutation

RQ for Ex. 1
RQ for Ex. 1

Gene Section MIER1 (mesoderm induction early response 1 homolog (Xenopus laevis))
Gene Section MIER1 (mesoderm induction early response 1 homolog (Xenopus laevis))

Cell Signaling
Cell Signaling

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Lecture 12

Editorial Focus: Epigenetic changes in gene expression: focus on
Editorial Focus: Epigenetic changes in gene expression: focus on

MAPTrix TM Biomimetic Library
MAPTrix TM Biomimetic Library

... Fibronectin naturally exists as a dimer, consisting of two nearly identical monomers. Two regions in each fibronectin subunit possess cell binding activity: III9-10 and III14-V (refer to the modular structure of fibronectin below). The primary receptor for adhesion to fibronectin commonly involves t ...
Basic Science for Clinicians
Basic Science for Clinicians

... mutations of the LDL receptor gene. Nevertheless, rapidmutation screening methods for FH have been developed.11 Familial defective apolipoprotein B (apoB), another relatively common hypercholesterolemia (⬇1 in 800), is the result of the mutations of apoB, the major protein of LDL, which prevent its ...
Mechanisms of Hormone Action: Steroid Receptors
Mechanisms of Hormone Action: Steroid Receptors

acbp-1
acbp-1

... fatty acids, are important intermediates in both anabolic and catabolic processes, but have also been identified as regulators of ion channels, enzymes, membrane fusion, and gene expression. Acyl-CoA binding protein (ACBP) is a small, primarily cytosolic protein, which binds acyl-CoA esters with hig ...
Slide 1 - McGill University
Slide 1 - McGill University

Lecture 8 Cell Signalling
Lecture 8 Cell Signalling

Chemical messengers 2007
Chemical messengers 2007

Keywords: Ethanol of Pinus koraiensis, 3T3
Keywords: Ethanol of Pinus koraiensis, 3T3

PEPTIDE HORMONES
PEPTIDE HORMONES

... Sizes, origins and fate: Due to the force of custom, “peptide hormones” is a collective name that has been applied to peptides, polypeptides and proteins that all function as hormones. The name “factor” has also been given to some of these peptides and originates from a time when their peptide/prot ...
Cell Communication Lecture ppt
Cell Communication Lecture ppt

... Various proteins activated ...
Acupuncture Reverses High Cholesterol Cell Fat
Acupuncture Reverses High Cholesterol Cell Fat

... laboratory research confirms that needling a specific acupuncture point located on the lower leg prevents and reverses the formation of foam cells. This type of cell forms at the site of fatty streaks and is the beginning of atherosclerotic plaque formation in blood vessels. The presence of foam cel ...
G-protein linked receptor
G-protein linked receptor

... G-protein coupled receptors also activate IP3 and Ca2+-mediated signaling pathways Activate receptor acts as GEF ...
MCB Lecture 3 – Gene Regulation
MCB Lecture 3 – Gene Regulation

... o Allolactose acts as an inducer. It binds to the repressor, so that the repressor is removed from the operon and transcription of the gene can occur by RNA Polymerase cAMP Responsive Protein (CRP or CAP) does what for the Lac Operon? o CRP (CAP) is an activator. cAMP levels are lowered by the prese ...
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SB-431542: Potent and selective inhibitor of activin receptor

The Bacillus subtilis lipoprotein LplA causes cell lysis
The Bacillus subtilis lipoprotein LplA causes cell lysis

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TITOLO

Gene Section CLTCL1 (clathrin heavy polypeptide-like 1) Atlas of Genetics and Cytogenetics
Gene Section CLTCL1 (clathrin heavy polypeptide-like 1) Atlas of Genetics and Cytogenetics

RECEPTORS STRUCTURE AND FUNCTION Chapter 4
RECEPTORS STRUCTURE AND FUNCTION Chapter 4

... another nerve. Usually short lived and responsible for messages between individual cells Hormones: Chemicals released from cells or glands and which travel some distance to bind with receptors on target cells throughout the body Note: Chemical messengers ‘switch on’ receptors without undergoing a re ...
α-N-Acetylgalactosaminidase as a tools in the synthesis of complex
α-N-Acetylgalactosaminidase as a tools in the synthesis of complex

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VLDL receptor



The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by T. Yamamoto, VLDLR is widely distributed throughout the tissues of the body, including the heart, skeletal muscle, adipose tissue, and the brain, but is absent from the liver. This receptor has an important role in cholesterol uptake, metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, and neuronal migration in the developing brain. In humans, VLDLR is encoded by the VLDLR gene. Mutations of this gene may lead to a variety of symptoms and diseases, which include type I lissencephaly, cerebellar hypoplasia, and atherosclerosis.
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