Biochemistry_Summary
... The metabolism( activation/inactivation) of receptors of the hormone in the target cell. The presence of factors within target cell necessary for the response. Up- or down-regulation of the receptor. Post-receptor desensitization of the cell >> down-regulation. ** There’re molecules within ...
... The metabolism( activation/inactivation) of receptors of the hormone in the target cell. The presence of factors within target cell necessary for the response. Up- or down-regulation of the receptor. Post-receptor desensitization of the cell >> down-regulation. ** There’re molecules within ...
Cholesterol Metabolism_MJH
... catalyzed by members of the cytochrome P450 enzyme superfamily. The human genome encodes 57 members of the cyt P450 superfamily, with tissue-specific expression and intracellular localization highly regulated. Some P450 enzymes are localized in mitochondria. ...
... catalyzed by members of the cytochrome P450 enzyme superfamily. The human genome encodes 57 members of the cyt P450 superfamily, with tissue-specific expression and intracellular localization highly regulated. Some P450 enzymes are localized in mitochondria. ...
ION CHANNELS AS DRUG TARGETS
... in most cells and open, thus hyperpolarizing the cell, when intracellular Ca2+ levels increases 2. ATP-sensitive potassium channels, which open when the intracellular ATP concentration falls because the cell is short of nutrients; • these channels which are distinct from those mediating the excitato ...
... in most cells and open, thus hyperpolarizing the cell, when intracellular Ca2+ levels increases 2. ATP-sensitive potassium channels, which open when the intracellular ATP concentration falls because the cell is short of nutrients; • these channels which are distinct from those mediating the excitato ...
Cytokine receptor signaling through the Jak–Stat–Socs pathway in
... Eight mammalian Socs proteins have been identified: Socs1–7 and cytokine-inducible SH2 protein (Cis). Members of the Socs family of proteins possess three domains: an N-terminal domain of variable length that is not well conserved between members and whose function remains largely unknown; a central ...
... Eight mammalian Socs proteins have been identified: Socs1–7 and cytokine-inducible SH2 protein (Cis). Members of the Socs family of proteins possess three domains: an N-terminal domain of variable length that is not well conserved between members and whose function remains largely unknown; a central ...
Vesicle formation and targeting is a multi
... Defects in LDL endocytosis are associated with “familial hypercholesterolemia”… –Severe atherosclerosis at early age (strokes and heart attacks in pre-teens) –Excess LDL in circulating blood –LDL not properly internalized by cells –Recessive/single gene… encoding plasma membrane receptor for LDL (L ...
... Defects in LDL endocytosis are associated with “familial hypercholesterolemia”… –Severe atherosclerosis at early age (strokes and heart attacks in pre-teens) –Excess LDL in circulating blood –LDL not properly internalized by cells –Recessive/single gene… encoding plasma membrane receptor for LDL (L ...
L07v02 Trp part1a final export.stamped_doc
... distance between these two arms, such that they will not sit down properly. Instead of sitting in over here, it sits down to maybe here and here. And so it cannot bind to both the major groups. [00:04:22.64] Again, this is just a consequence of having too much tryptophan in the cell or a sufficient ...
... distance between these two arms, such that they will not sit down properly. Instead of sitting in over here, it sits down to maybe here and here. And so it cannot bind to both the major groups. [00:04:22.64] Again, this is just a consequence of having too much tryptophan in the cell or a sufficient ...
AP Biology
... (c) Hormonal signaling. Specialized endocrine cells secrete hormones into body fluids, often the blood. Hormones may reach virtually all C body cells. ...
... (c) Hormonal signaling. Specialized endocrine cells secrete hormones into body fluids, often the blood. Hormones may reach virtually all C body cells. ...
Cell Communication Lecture
... (c) Hormonal signaling. Specialized endocrine cells secrete hormones into body fluids, often the blood. Hormones may reach virtually all C body cells. ...
... (c) Hormonal signaling. Specialized endocrine cells secrete hormones into body fluids, often the blood. Hormones may reach virtually all C body cells. ...
Viral hepatitis and fatty liver disease: how an
... LXREs and SREs (sterol-response elements) in the SREBP1c promoter [7]. In addition, HCV core protein and non-structural protein-4b also activated SREBPs [8]. In the light of Kim et al.’s study on HBx [2], it would be interesting to determine whether any of these HCV proteins also act through binding ...
... LXREs and SREs (sterol-response elements) in the SREBP1c promoter [7]. In addition, HCV core protein and non-structural protein-4b also activated SREBPs [8]. In the light of Kim et al.’s study on HBx [2], it would be interesting to determine whether any of these HCV proteins also act through binding ...
VLDL receptor
The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by T. Yamamoto, VLDLR is widely distributed throughout the tissues of the body, including the heart, skeletal muscle, adipose tissue, and the brain, but is absent from the liver. This receptor has an important role in cholesterol uptake, metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, and neuronal migration in the developing brain. In humans, VLDLR is encoded by the VLDLR gene. Mutations of this gene may lead to a variety of symptoms and diseases, which include type I lissencephaly, cerebellar hypoplasia, and atherosclerosis.