Malaria based proteomics of erythrocyte surface proteins
... New malaria drugs are expensive & limited in supply ...
... New malaria drugs are expensive & limited in supply ...
Genes Section DEK (DEK oncogene) Atlas of Genetics and Cytogenetics
... specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol 1992 Apr;12(4):1687-97. ...
... specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol 1992 Apr;12(4):1687-97. ...
Automated Assignment of Backbone NMR Data
... sets of chemical shifts. This produces sequentially linked residues that are subsets of the full-length protein sequence. Each subset can be abstracted and treated as a single pseudoresidue with Cα and Cβ of i and i – 1 corresponding to the chemical shifts of the residues making up the front and bac ...
... sets of chemical shifts. This produces sequentially linked residues that are subsets of the full-length protein sequence. Each subset can be abstracted and treated as a single pseudoresidue with Cα and Cβ of i and i – 1 corresponding to the chemical shifts of the residues making up the front and bac ...
GenScript - Protein Services
... Other features that may cause difficulty in either expression or purification (Please specify): ...
... Other features that may cause difficulty in either expression or purification (Please specify): ...
Protein Purification 2003
... • Has a wide range of application • Relies on fact that proteins loose solubility as concentration of salt is increased – Is characteristic of particular protein – Results in a partial purification of all proteins with similar solubility characteristics – Must determine [amm sulf] to precipitate you ...
... • Has a wide range of application • Relies on fact that proteins loose solubility as concentration of salt is increased – Is characteristic of particular protein – Results in a partial purification of all proteins with similar solubility characteristics – Must determine [amm sulf] to precipitate you ...
title page
... kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170 HUA2 Cytoplasmic protein of unknown function; computational analysis of large-scale proteinYOR284w protein interaction data suggests a possible role ...
... kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170 HUA2 Cytoplasmic protein of unknown function; computational analysis of large-scale proteinYOR284w protein interaction data suggests a possible role ...
The Amino Acid Sequence of Chlorella fusca Plastocyanin
... binding of the copper. The proposed sequence contains only a single cysteine residue (position 83), clustered around by several aromatic residues. In the bacterial azurins, which are copper proteins that are believed to be of structure and function comparable with those of plastocyanin (Malkin & Mal ...
... binding of the copper. The proposed sequence contains only a single cysteine residue (position 83), clustered around by several aromatic residues. In the bacterial azurins, which are copper proteins that are believed to be of structure and function comparable with those of plastocyanin (Malkin & Mal ...
REVIEWS
... Figure 1 | The effects of the endoplasmic reticulum environment on folding equilibria. The equilibrium between the native (N) and incompletely folded (I) forms of a protein (green) in the endoplasmic reticulum (ER) is affected by the ER environment, in particular by the presence of molecular chapero ...
... Figure 1 | The effects of the endoplasmic reticulum environment on folding equilibria. The equilibrium between the native (N) and incompletely folded (I) forms of a protein (green) in the endoplasmic reticulum (ER) is affected by the ER environment, in particular by the presence of molecular chapero ...
1. Inter-chain disulfide bonds
... J chain linked to Fc regions. - When IgA is found in secretions:, it also has another protein associated with it called the secretory piece or T piece. The secretory piece helps IgA to be transported across mucosa and also protects it from degradation in the secretions. ...
... J chain linked to Fc regions. - When IgA is found in secretions:, it also has another protein associated with it called the secretory piece or T piece. The secretory piece helps IgA to be transported across mucosa and also protects it from degradation in the secretions. ...
Dynamic allostery as revealed by computational simulations: the
... occurs when there is an energetic coupling between different regions of the protein and binding of a ligand to one site modifies the function of another, distant site. Since the first models proposed in the 1960's, allostery has been considered from a mechanical point of view, according to which the ...
... occurs when there is an energetic coupling between different regions of the protein and binding of a ligand to one site modifies the function of another, distant site. Since the first models proposed in the 1960's, allostery has been considered from a mechanical point of view, according to which the ...
Powerpoint slides - School of Engineering and Applied Science
... Secondary structure: Interactions that occur between the C=O and N-H groups on amino acids Much of the protein core comprises helices and sheets, folded into a threedimensional configuration: ...
... Secondary structure: Interactions that occur between the C=O and N-H groups on amino acids Much of the protein core comprises helices and sheets, folded into a threedimensional configuration: ...
interrpo_nov16
... positions within a multiple sequence alignment • Patterns • Profiles • Profile HMMs Use these models (signatures) to infer relationships with the characterised sequences from which the alignment was constructed Approach used by a variety of databases: Pfam, TIGRFAMs, PANTHER, Prosite, etc ...
... positions within a multiple sequence alignment • Patterns • Profiles • Profile HMMs Use these models (signatures) to infer relationships with the characterised sequences from which the alignment was constructed Approach used by a variety of databases: Pfam, TIGRFAMs, PANTHER, Prosite, etc ...
Guidelines for Abstract Submission
... N-terminal region. In order to identify residues important for chloroplast and/or mitochondria targeting, we introduced point mutations and deletions into conserved residues of RBP1b TS, and evaluated their effect in the relative mitochondria/chloroplast targeting, using a novel GFP quantitative app ...
... N-terminal region. In order to identify residues important for chloroplast and/or mitochondria targeting, we introduced point mutations and deletions into conserved residues of RBP1b TS, and evaluated their effect in the relative mitochondria/chloroplast targeting, using a novel GFP quantitative app ...
A Statistical Analysis of the Linear Interaction Energy Method
... in terms of these models • Induced fit assumed if there is no experimental evidence for a pre-existing equilibrium of multiple conformations • Note that strictly this is an artificial distinction ...
... in terms of these models • Induced fit assumed if there is no experimental evidence for a pre-existing equilibrium of multiple conformations • Note that strictly this is an artificial distinction ...
15.Flexible_Protein_Docking_Jonathan
... in terms of these models • Induced fit assumed if there is no experimental evidence for a pre-existing equilibrium of multiple conformations • Note that strictly this is an artificial distinction ...
... in terms of these models • Induced fit assumed if there is no experimental evidence for a pre-existing equilibrium of multiple conformations • Note that strictly this is an artificial distinction ...
Protein Degradation, Volume 1 ch01_p 1..9
... intake, and to account for a minor part of nitrogenous compounds excreted in the urine. Because of the minor proportion of ‘‘endogenous’’ protein catabolism, it was thought that cellular proteins are predominantly stable, and only a small fraction resulting from ‘‘wear and tear’’ of tissue proteins ...
... intake, and to account for a minor part of nitrogenous compounds excreted in the urine. Because of the minor proportion of ‘‘endogenous’’ protein catabolism, it was thought that cellular proteins are predominantly stable, and only a small fraction resulting from ‘‘wear and tear’’ of tissue proteins ...
Leukaemia Section t(11;14)(p13;q11), t(7;11)(q35;p13) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... has been found in one case of T-ALL. Variants t(11;14)(p13;q11) and t(7;11)(q35;p13) are variant translocations of each other. ...
... has been found in one case of T-ALL. Variants t(11;14)(p13;q11) and t(7;11)(q35;p13) are variant translocations of each other. ...
a study of intelligent techniques for protein secondary structure
... helices, beta sheets, and turns based on known protein structures solved with X-ray crystallography. From these frequencies a set of probability parameters were derived for the appearance of each amino acid in each secondary structure type, and these parameters are used to predict the probability th ...
... helices, beta sheets, and turns based on known protein structures solved with X-ray crystallography. From these frequencies a set of probability parameters were derived for the appearance of each amino acid in each secondary structure type, and these parameters are used to predict the probability th ...
Using PEPscreen to Study Protein Phosphorylation - Sigma
... included in a single KiC assay.5 Using this reaction scale, their most recent use of the PEPscreen technology involves a library of 377 peptide sequences of in vivo phosphorylation sites, to examine phosphorylation by 77 different protein kinases from A. thaliana.8 Ahsan et al. chose the sequences f ...
... included in a single KiC assay.5 Using this reaction scale, their most recent use of the PEPscreen technology involves a library of 377 peptide sequences of in vivo phosphorylation sites, to examine phosphorylation by 77 different protein kinases from A. thaliana.8 Ahsan et al. chose the sequences f ...
Document
... products or as plasma expanders. The latter application is rapidly being replaced by purified Albumin solutions. Thawing of FFP results in persistence of an insoluble fraction = cryoprecipitate enriched in F8-vWF and other coagulation factors and that can be used either directly (for vWillebrand's d ...
... products or as plasma expanders. The latter application is rapidly being replaced by purified Albumin solutions. Thawing of FFP results in persistence of an insoluble fraction = cryoprecipitate enriched in F8-vWF and other coagulation factors and that can be used either directly (for vWillebrand's d ...
Evolution of a novel organelle in insects
... all eukaryotes and plants, respectively. During their evolution, many genes were transferred from ancestral organelles and other bacteria to the host genome. This process required incorporating intact genes into the host genome, acquiring the expression signals that enable their transcription in euk ...
... all eukaryotes and plants, respectively. During their evolution, many genes were transferred from ancestral organelles and other bacteria to the host genome. This process required incorporating intact genes into the host genome, acquiring the expression signals that enable their transcription in euk ...
Rubric
... Protein Mini-Posters - DUE THURSDAY 12/3/15! You have three class periods to work on this project – two library days and one in class period. Your project drops one full grade for each day it is late. Using the information you found about your chosen complete and incomplete protein, create a mini po ...
... Protein Mini-Posters - DUE THURSDAY 12/3/15! You have three class periods to work on this project – two library days and one in class period. Your project drops one full grade for each day it is late. Using the information you found about your chosen complete and incomplete protein, create a mini po ...
Protein folding
Protein folding is the process by which a protein structure assumes its functional shape or conformation. It is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from random coil.Each protein exists as an unfolded polypeptide or random coil when translated from a sequence of mRNA to a linear chain of amino acids. This polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), known as the native state. The resulting three-dimensional structure is determined by the amino acid sequence (Anfinsen's dogma). Experiments beginning in the 1980s indicate the codon for an amino acid can also influence protein structure.The correct three-dimensional structure is essential to function, although some parts of functional proteins may remain unfolded, so that protein dynamics is important. Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality. Several neurodegenerative and other diseases are believed to result from the accumulation of amyloid fibrils formed by misfolded proteins. Many allergies are caused by incorrect folding of some proteins, because the immune system does not produce antibodies for certain protein structures.