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Overgeneralized autobiographical memory and future
Overgeneralized autobiographical memory and future

... describe a recent memory (past month), a remote memory (past 5e20 years), a recent anticipated event (next month) or a remote anticipated event (next 5e20 years) that the cue word evoked. Time frame (recent/remote) was manipulated because previous work shows that past and future event phenomenology, ...
A first-principle for the nervous system
A first-principle for the nervous system

... During associative learning of two stimuli, the inputs are expected to converge at certain locations to induce a specific change such that at a later time, the presence of one stimulus can reactivate this change for inducing the internal sensation of memory of the second stimulus (Fig.1a). The next ...
Synaptic Pruning in Development: A Novel Account in Neural Terms
Synaptic Pruning in Development: A Novel Account in Neural Terms

... (e.g. 2 weeks for the macaque monkeys [Bourgeois, 1993]). The changes in synaptic density are not a result of changes in total brain volume, but re ect true synaptic elimination [Rakic et al., 1994]. In some cases, synaptic elimination was shown to be correlated with experience-dependent activity [S ...
Distinct or Gradually Changing Spatial and Nonspatial
Distinct or Gradually Changing Spatial and Nonspatial

... out a continuous theta oscillation. Moreover, the nature of theta oscillation in the bat’s dorsal hippocampus was intermittent (Ulanovsky and Moss, 2007), much like the intermittent theta reported by Royer et al. (2010) in the rat ventral hippocampus. The existence of place cells without continuous ...
slides
slides

... Spatial pretraining can separate the two kinds of learning Rats first made familiar with the general task requirements and subsequently trained after receiving NMDAR antagonists could learn the spatial location as quickly as controls (report from Cain's group, 1995) or showed (to some extent) improv ...
Ullman, 2004 - Brain and Language Lab
Ullman, 2004 - Brain and Language Lab

... particular set of inputs and outputs. This type of brain organization has been claimed for the cerebellum, for various sub-cortical structures, including the basal ganglia, and for certain cortical regions, in particular in frontal cortex (Alexander, DeLong, & Strick, 1986; Middleton & Strick, 2000a ...
Memory formation: from network structure to neural dynamics
Memory formation: from network structure to neural dynamics

... 1993; Gray 1999) postulates that correlated neuronal activity mediates rapid feature binding and thus the formation of intermittent functional ensembles in the brain. Therefore, the problem of identifying these functional neural ensembles can potentially be reduced to the identification of temporally ...
This article was originally published in the Encyclopedia of
This article was originally published in the Encyclopedia of

... letter, they might be asked to press the same key as quickly as possible, unless they see the letter X, for which they must withhold their response. The percentage of no-go trials successfully withheld is a metric of inhibitory control ability. Another approach used to study motor stopping is the st ...
The seasonal hippocampus of food-storing birds.
The seasonal hippocampus of food-storing birds.

... time with a cell-birth marker such as tritiated thymidine or bromodeoxyuridine (BrdU). Cell-birth markers are incorporated into the nucleus of dividing cells during the S-phase of mitosis and the marker can later be detected by autoradiography or immunocytochemistry. In Barnea and Nottebohm’s study, ...
The speed of learning instructed stimulus
The speed of learning instructed stimulus

... Keywords: Rapid instructed task learning, Pre-frontal cortex, Inferior-temporal Cortex, Hippocampus, synaptic learning Abstract Humans can learn associations between visual stimuli and motor responses from just a single instruction. This is known to be a fast process, but how fast is it? To answer t ...
Running Improves Pattern Separation during Novel Object
Running Improves Pattern Separation during Novel Object

... molecular layer. As a consequence there might be a 4times larger chance for the formation of new synapses of young cells with axon terminals projecting from the entorhinal cortex. Taken together, the data not only show that the animals make use of running wheels, leading to the well-known increase i ...
The hippocampal–striatal axis in learning, prediction and
The hippocampal–striatal axis in learning, prediction and

... Various parallel loops have been associated with different types of motor and cognitive function. Oculomotor and somatic motor loops originate in the frontal eye fields and (pre)motor cortices, but cognitive and motivationalaffective loops associated with prefrontal cortex (PFC), amygdala and HPC ha ...
Higher-Order Functions
Higher-Order Functions

... diencephalon, plays an uncertain role in memory storage and retrieval. Damage to this nucleus is associated with changes in emotional states, memory, and intellectual function. ...
Dopamine and adaptive memory - Shohamy Lab
Dopamine and adaptive memory - Shohamy Lab

... guide later choices. By integrating findings from both human and animal research, we argue for a framework in which dopamine helps create enriched mnemonic representations of the environment to support adaptive behavior. The hippocampus: Creating building blocks for memory-guided behavior After deca ...
Distributed patterns of reactivation predict vividness of recollection.
Distributed patterns of reactivation predict vividness of recollection.

... and Cabeza (2015) have also shown that stimulus-specific reactivation increases linearly as a function of the number of details recalled for consciously retrieved images. These findings suggest that recollection and reactivation are different facets (one subjective, one objective) of the same under ...
Modeling goal-directed spatial navigation in the rat based on physiological
Modeling goal-directed spatial navigation in the rat based on physiological

... spatial navigation tasks in a T-maze. The roles of neuron populations (ECII, ECIII, CA3, CA1) are based on hypothesized functions of these individual regions in spatial learning and recall tasks. Instead of static data sets, environmental input to model networks changes in accordance with task-speci ...
Epistatic interaction of CREB1 and KCNJ6 on rumination and
Epistatic interaction of CREB1 and KCNJ6 on rumination and

... in cultured hippocampal neurons demonstrating that GIRK channels are critical for excitatory synaptic plasticity which is considered a cellular correlate of learning and memory (Chung et al., 2009a,b). CREB1 is a member of the leucine zipper family of DNAbinding proteins (Sands and Palmer, 2008). Th ...
ManuscriptPTA_R1_FINAL - Spiral
ManuscriptPTA_R1_FINAL - Spiral

... within the Default Mode Network can be assessed using resting state functional magnetic resonance imaging, which can be acquired in confused patients unable to perform tasks in the scanner. Here we used this approach to test the hypothesis that the mnemonic symptoms of post-traumatic amnesia are cau ...
8 pages - Science for Monks
8 pages - Science for Monks

... person who knows they are dreaming —or, if not, when they wake they are able to narrate their dream sequence by sequence. So what happens during sleep? There are no external stimuli. The brain is by itself with its own intrinsic activity, and this intrinsic activity is largely dependent on how my ne ...
Using neuroimaging to evaluate models of working memory and
Using neuroimaging to evaluate models of working memory and

... refers to the advantage in immediate serial recall for items that sound distinct (e.g. pig, bun, car), as compared to items that sound alike (e.g. mat, mad, map) (Conrad, Freeman, & Hull, 1965), and is assumed to arise from interference among items in the store having a similar phonological code. Th ...
The Three Amnesias - University of Florida College of Public Health
The Three Amnesias - University of Florida College of Public Health

... information that has not been personally encountered (e.g., details regarding the recent war in Iraq). Kapur (1999) suggests that autobiographical memory for past personal events is both anatomically and functionally distinct from remote semantic knowledge and fact memory, and some case studies and ...
Emotional Arousal and Memory Binding
Emotional Arousal and Memory Binding

... pay more attention to them. Brain-imaging studies reveal that people show more activation in visual-processing regions for emotionally intense pictures than they do for emotionally neutral pictures (e.g., M.A. Bradley et al., 2003; Mather et al., 2006). These differences occur even when emotional an ...
Brain days-Part V-Limbic
Brain days-Part V-Limbic

... mistake. The damage of this circuit results in emotional disorders especially deep apathy and lack of spontaneity. Lowered mood is accompanied by weakening of affect and motor adynamy. It was shown that the anterior cingulate loop is responsible for correcting behavior following a mistake. ...
3.05 Neural Substrates of Remembering – Electroencephalographic
3.05 Neural Substrates of Remembering – Electroencephalographic

... recordings using a mastoid or average-mastoid reference, because this recording method is used in a majority of the relevant memory studies. Like any reference that can be used during recording or digitally created afterward, the mastoid reference is not inactive, as potentials generated near this l ...
Molecular Mechanisms of Learning and Memory
Molecular Mechanisms of Learning and Memory

... • Learn to associate a response with a meaningful stimulus, e.g., reward lever pressing for food • Complex neural circuits related to role played by ...
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Memory consolidation



Memory consolidation is a category of processes that stabilize a memory trace after its initial acquisition. Consolidation is distinguished into two specific processes, synaptic consolidation, which is synonymous with late-phase LTP and occurs within the first few hours after learning, and systems consolidation, where hippocampus-dependent memories become independent of the hippocampus over a period of weeks to years. Recently, a third process has become the focus of research, reconsolidation, in which previously-consolidated memories can be made labile again through reactivation of the memory trace.
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