Chapter 13 Hypersensitivity Reactions
... - excess immune complexes are deposited in the capillary walls which activate complement generating anaphylotoxins and C3b - C5a attracts neutrophils - C5a also binds to mast cells and causes release of inflammatory mediators that increase vascular permeability - Neutrophils phagocytose (C3b, IgG) - ...
... - excess immune complexes are deposited in the capillary walls which activate complement generating anaphylotoxins and C3b - C5a attracts neutrophils - C5a also binds to mast cells and causes release of inflammatory mediators that increase vascular permeability - Neutrophils phagocytose (C3b, IgG) - ...
Immunity
... injected and it stimulates the immune system to develop protective immunity against that organism, but the antigen does not itself cause the pathogenic effects of ...
... injected and it stimulates the immune system to develop protective immunity against that organism, but the antigen does not itself cause the pathogenic effects of ...
Epitope mapping
... antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as ...
... antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as ...
Immunology Basics 1 - 8 Oct 2015
... and killer T lymphocytes IN FACT - these are not as clearcut and there are many examples of both these ‘systems’ co-operating ...
... and killer T lymphocytes IN FACT - these are not as clearcut and there are many examples of both these ‘systems’ co-operating ...
Primary and Secondary Immune Response: Lectuer-9
... Primary Immune Response to initial antigenic stimulus is slow, sluggish, short live with a long lage phase and low antibody titer that do not persist for along time ,antibody formed are 1gM. When tetans toxoid is given to host an immune response is mounted .The response could be detected intervally ...
... Primary Immune Response to initial antigenic stimulus is slow, sluggish, short live with a long lage phase and low antibody titer that do not persist for along time ,antibody formed are 1gM. When tetans toxoid is given to host an immune response is mounted .The response could be detected intervally ...
MALARIAL VACCINES
... Modification of Glucose-6phosphate dehydrogenase Ovalocytosis Duffy Ag–protects against P.vivax infection ...
... Modification of Glucose-6phosphate dehydrogenase Ovalocytosis Duffy Ag–protects against P.vivax infection ...
lecture3-Cell Mediated Immunity (2014)
... • Production of IL-2 and its receptor – IL-2 is also know as T cell growth factor – Proliferation of antigen specific T cells – Effector and regulatory cells are produced along with “memory” cells – IL-2 also stimulates CD8 cytotoxic cells • Production of Interferons – Enhances anti-microbial activi ...
... • Production of IL-2 and its receptor – IL-2 is also know as T cell growth factor – Proliferation of antigen specific T cells – Effector and regulatory cells are produced along with “memory” cells – IL-2 also stimulates CD8 cytotoxic cells • Production of Interferons – Enhances anti-microbial activi ...
Lecture3 - Cell Mediated Immunity
... • Production of IL-2 and its receptor – IL-2 is also know as T cell growth factor – Proliferation of antigen specific T cells – Effector and regulatory cells are produced along with “memory” cells – IL-2 also stimulates CD8 cytotoxic cells • Production of Interferons – Enhances anti-microbial activi ...
... • Production of IL-2 and its receptor – IL-2 is also know as T cell growth factor – Proliferation of antigen specific T cells – Effector and regulatory cells are produced along with “memory” cells – IL-2 also stimulates CD8 cytotoxic cells • Production of Interferons – Enhances anti-microbial activi ...
Immunogens, Antigens, and Haptens Initiation of immune response
... for comprehensive surveillance by CD8 T cells • Only some cells express high levels of MHC II and MHC I • These are B cells, macrophages, dendritic cells and thymic epithelial cells. • B cells, macrophages and dendritic cells are called professional antigenpresenting cells (APC). • IFN-g increases t ...
... for comprehensive surveillance by CD8 T cells • Only some cells express high levels of MHC II and MHC I • These are B cells, macrophages, dendritic cells and thymic epithelial cells. • B cells, macrophages and dendritic cells are called professional antigenpresenting cells (APC). • IFN-g increases t ...
ImmunLec22
... inflammation, thus reducing the patient's susceptibility to a sudden attack. Most of these medications are steroids, although there are some widely used non-steroidal anti-inflammatory medications. ...
... inflammation, thus reducing the patient's susceptibility to a sudden attack. Most of these medications are steroids, although there are some widely used non-steroidal anti-inflammatory medications. ...
Ouchterlony Procedure
... attach to mast cells and basophils. When antigens bind, they signal release of histamine. IgA - A dimer - Produced by cells in the mucus membranes to prevent attachment of pathogens. IgA is also found in many body secretions including milk. IgM - A pentamer - First antibody to appear following expos ...
... attach to mast cells and basophils. When antigens bind, they signal release of histamine. IgA - A dimer - Produced by cells in the mucus membranes to prevent attachment of pathogens. IgA is also found in many body secretions including milk. IgM - A pentamer - First antibody to appear following expos ...
APC & Antigen presentation
... complement, and MHC. Birbeck granule is the characteristic organelle. After capturing antigen in the tissues by phagocytosis or by endocytosis. DC migrate into the blood or lymph and circulate to lymphoid organs, become IDC（right）。 ...
... complement, and MHC. Birbeck granule is the characteristic organelle. After capturing antigen in the tissues by phagocytosis or by endocytosis. DC migrate into the blood or lymph and circulate to lymphoid organs, become IDC（right）。 ...
Chapter 3. Antigens
... Antigen: Substances that can be recognized by the surface antibody (B cells) or by the TCR (T cells) when associated with MHC molecules Immunogenicity VS Antigenicity: Immunogenicity – ability to induce an antibody and/or cell-mediated immune response Antigenicity – ability to combine with the final ...
... Antigen: Substances that can be recognized by the surface antibody (B cells) or by the TCR (T cells) when associated with MHC molecules Immunogenicity VS Antigenicity: Immunogenicity – ability to induce an antibody and/or cell-mediated immune response Antigenicity – ability to combine with the final ...
Importance of Cell Surfaces
... B-cells recognize intact antigens using immunoglobulin (antibody) as their receptor T-cells have evolved to recognize antigens originating from within other cells using their T-cell antigen receptors (TCRs) ...
... B-cells recognize intact antigens using immunoglobulin (antibody) as their receptor T-cells have evolved to recognize antigens originating from within other cells using their T-cell antigen receptors (TCRs) ...
幻灯片 1
... 2. Can induce immature and mature B cell-mediate immune response 3. In high concentrations, can induce polyclonal B-cell activation 4. In lower concentrations, only the BCR-binding TI-1 antigens can activate B cells 5. Not able to induce Ig class switch, antibody affinity maturation and memory B cel ...
... 2. Can induce immature and mature B cell-mediate immune response 3. In high concentrations, can induce polyclonal B-cell activation 4. In lower concentrations, only the BCR-binding TI-1 antigens can activate B cells 5. Not able to induce Ig class switch, antibody affinity maturation and memory B cel ...
Chapter 1 – Testbank Multiple Choice Questions
... 12. Optimal pH has not been determined for immunohematologic testing, but it is generally believed that testing should be performed within what pH range? a. 4.2–5.8 b. 5.8–7.5 c. 6.8–7.2 d. 7.0–8.8 Answer: c 13. All of the following statements are true about the second step of the agglutination proc ...
... 12. Optimal pH has not been determined for immunohematologic testing, but it is generally believed that testing should be performed within what pH range? a. 4.2–5.8 b. 5.8–7.5 c. 6.8–7.2 d. 7.0–8.8 Answer: c 13. All of the following statements are true about the second step of the agglutination proc ...
Chapter 3. Antigens
... - The IgA and IgM found in external secretions differs from that found in serum by the presence of an additional component referred to as the "secretory component". ...
... - The IgA and IgM found in external secretions differs from that found in serum by the presence of an additional component referred to as the "secretory component". ...
Antibody Production and Use in Immunodetection
... antibody molecules with slightly different amino acid sequences that can further tested to find the one with the most affinity for an antigen The recombinant DNA can be engineered to encode a human antibody molecule with the binding portion of a mouse. This type of antibody is called “humanized” o ...
... antibody molecules with slightly different amino acid sequences that can further tested to find the one with the most affinity for an antigen The recombinant DNA can be engineered to encode a human antibody molecule with the binding portion of a mouse. This type of antibody is called “humanized” o ...
Nature of the Immune System The Immune Response
... Molecular size The higher the molecular weight, the better the molecule will function as an antigen. The larger the size, the greater the number of antigenic sites and the greater the variety and amount of antibody production. Molecules with a molecular weight of less than 10,000 daltons have no ...
... Molecular size The higher the molecular weight, the better the molecule will function as an antigen. The larger the size, the greater the number of antigenic sites and the greater the variety and amount of antibody production. Molecules with a molecular weight of less than 10,000 daltons have no ...
Chapter 19: Disorders of the Immune System
... Blood type “O” individuals (tolerate type O blood only) • do not produce type A or type B antigens • produce antibodies to type A and B antigens and thus will lyse type A, B or AB RBCs via complement ...
... Blood type “O” individuals (tolerate type O blood only) • do not produce type A or type B antigens • produce antibodies to type A and B antigens and thus will lyse type A, B or AB RBCs via complement ...
Immune System
... a. Secreted by virus-infected cells b. Stimulates non-infected cells to make proteins that block viral protein synthesis c. Slows infection to allow specific defenses to ...
... a. Secreted by virus-infected cells b. Stimulates non-infected cells to make proteins that block viral protein synthesis c. Slows infection to allow specific defenses to ...
Medical Immunology
... increased expression of class II MHC and costimulatory B7. Antigen–BCR complexes are internalized by receptor-mediated endocytosis and degraded to peptides, which are bound by class II MHC and presented as peptide–MHC complexes. Th cell recognizes Ag–class II MHC and B7-CD28 co-stimulation on Bcell ...
... increased expression of class II MHC and costimulatory B7. Antigen–BCR complexes are internalized by receptor-mediated endocytosis and degraded to peptides, which are bound by class II MHC and presented as peptide–MHC complexes. Th cell recognizes Ag–class II MHC and B7-CD28 co-stimulation on Bcell ...
Immune System Lyrics (Parts 1 and 2)
... And here’s a little something, that’s trying to infect us.” We gotta do something, or this’ll be the end of us.” Our phagocytic sentinels use MHC class 2, And holding up their antigen they make their move To lymph nodes, where they bind with a Helper T Whose receptor is also complementary, To the an ...
... And here’s a little something, that’s trying to infect us.” We gotta do something, or this’ll be the end of us.” Our phagocytic sentinels use MHC class 2, And holding up their antigen they make their move To lymph nodes, where they bind with a Helper T Whose receptor is also complementary, To the an ...
Immunology Review
... When the zeta potential is lowered, the red cells can more closely approach each other, allowing antibodies to crosslink antigens between cells. ...
... When the zeta potential is lowered, the red cells can more closely approach each other, allowing antibodies to crosslink antigens between cells. ...
Chapter 14 Lymphatic System Student outline
... a. A helper T-cell becomes __________ when it encounters antigens for which it is specialized to react. b. The activated T-cell contacts a B-cell that carries the foreign antigen the T-cell encountered c. In response the T-cell secretes cytokines and stimulates B-cell proliferation and ____________ ...
... a. A helper T-cell becomes __________ when it encounters antigens for which it is specialized to react. b. The activated T-cell contacts a B-cell that carries the foreign antigen the T-cell encountered c. In response the T-cell secretes cytokines and stimulates B-cell proliferation and ____________ ...