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Chapter 43: The Immune System 1. Innate Immunity 2. Adaptive Immunity
Chapter 43: The Immune System 1. Innate Immunity 2. Adaptive Immunity

... Autoimmunity refers to the generation of an immune response to self antigens: • normally the body prevents such reactions • T cells with receptors that bind self antigens are eliminated (or rendered anergic*) in the thymus • B cells with antibodies that bind self antigens are eliminated or rendered ...
AntibodyNoTP
AntibodyNoTP

... (1 and 2: Like any other proteins with multiple molecular forms) 3. Different antigen-recognition abilities: Anti-idiotype Antibodies. Anti-CDR’s for different antibodies Other proteins except for T-cell Receptors do not show these kinds of variations and are not immunogenic in this way ...
Chapter 15 Cellular Mediated immunity 1. Define immunity providing
Chapter 15 Cellular Mediated immunity 1. Define immunity providing

... 13. Where do B cell mature in the human body? Where do T cells mature? (4 pts) 14. Where do B and T cell go after maturation? (2pts) 15. What are natural killer (NK) or cytotoxic killer (Tc) cells? a. What are their functions? (6 pts) ...
L6 APC Memory Cells
L6 APC Memory Cells

... PrimaryAResponse ...
Chapter 17- Specific Defenses of the Host :The
Chapter 17- Specific Defenses of the Host :The

... -initial contact w/ antigen- person’s serum has no detectable antibodies for several days, slow rise in antibody titer, first IgM antibodies are produced, followed by IgG, then gradual decline in antibody titer- pattern= primary response - immune response of host intensifies after second exposure- s ...
Document
Document

... Documentation of the clinical course occurring over the 30 days after infusion offers insight into the systemic inflammatory response syndrome in the absence of contaminating pathogens, endotoxin, or underlying disease. ...
Document
Document

... Human leukocyte antigens - first detected on leukocytes ...
B. Cell-Mediated Immunity
B. Cell-Mediated Immunity

... 1) very large - about 5-10% of the antibodies in serum 2) pentamer – 5 monomers held together by a peptide J (joining) chain 3) generally stay in blood ( too large to move into tissues) 4) predominant antibody that responds to red blood cell (ABO group)surface antigens 5) effective at aggregating an ...
Chapter 5 Immunity, Hypersensitivity, Allergy, and Autoimmune
Chapter 5 Immunity, Hypersensitivity, Allergy, and Autoimmune

... Specific populations of lymphocytes perform specific functions. Cells of immune system communicate and produce their effects by secreting cytokines. TYPES OF IMMUNITY AUTOIMMUNITY DEVELOPMENT OF THE LYMPHATIC SYSTEM Immature lymphocytes develop immune competence in thymus (T lymphocytes) or bone mar ...
ANTIGENS AND ANTIBODIES. STRUCTURE OF IMMUNE SYSTEM
ANTIGENS AND ANTIBODIES. STRUCTURE OF IMMUNE SYSTEM

... MHC genes and proteins are also important in two other medical contexts. One is that many autoimmune diseases occur in people who carry certain MHC genes, and the other is that the success of organ transplants is, in large part, determined by the compatibility of the MHC genes of the donor and recip ...
The secondary antibody
The secondary antibody

... system structure produces antibodies? ...
PowerPoint
PowerPoint

... immune system – this allows for selective destruction of invading pathogens without destruction of host tissues – involves major histocompatibility complex ...
Immunology MCQ exam 1. All of the following are true with respect
Immunology MCQ exam 1. All of the following are true with respect

... A. These are both surface glycoproteins expressed on T-cells. B. These serve to distinguish different types of T-cells, e.g., helper, suppressor and cytotoxic, from each other. C. These are not found associated with immunoglobulins. D. The T4 proteins serve both to mediate T-cell helper function as ...
B antigen
B antigen

... • ABO subgroups differ in the amount of antigen present on the red blood cell membrane – Subgroups have less antigen • Subgroups are the result of less effective enzymes. They are not as efficient in converting H antigens to A or B antigens (fewer antigens are present on the RBC) • Subgroups of A ar ...
IMMUNE EFFECTOR MECHANISMS
IMMUNE EFFECTOR MECHANISMS

... Case 52 Drug-Induced Serum Sickness – antibodies against penicillin cause vasculitis, hemorrhage ...
Immunology 1
Immunology 1

... recognise whole antigens. T lymphocytes do NOT however, recognize whole antigens, only a epitope of an antigen presented to them by an APC, such as a Dendritic cell, if the epitope is complementary to that particular T cell’s receptor. A number of different kinds of T cells exist, containing differe ...
6. ABO and H Blood Groups
6. ABO and H Blood Groups

... In individuals who inherit two h genes, A and B gene function is not blocked. In other words, the A and B gene-specified transferase enzymes are still produced (dependent, of course, on the inheritance of an A or B or both genes) but because of lack of H (L-fucose) on the type 1 or type 2 precursor ...
Chapter 43 - The Immune System
Chapter 43 - The Immune System

... cell activation eventually leading to the formation of cells that secrete a soluble form of the receptor ◦ The secreted protein is an antibody or immunoglobulin (Ig) ...
Lec
Lec

... person is protected against the invading disease. Activated T cells will last for a few weeks if transfused from another person, and for a few hours to a few days if transfused from an animal. The transfusion of antibodies or lymphocytes to confer immunity is called passive immunity. Allergy One of ...
Chapter 20-22 Lymphatic System
Chapter 20-22 Lymphatic System

... - fast response immunity - mechanisms are: a.) species resistance – our internal envir. is not suitable for certain pathogens – we can’t get distemper or plant diseases b.) mechanical & chemical barriers – skin, mucus (traps pathogens), sebum (contains pathogen inhibitors), enzymes (hydrolyze pathog ...
immune complex-mediated (type iii) hypersensitivity
immune complex-mediated (type iii) hypersensitivity

... typically in vessel walls, or the complexes are formed at extravascular sites where antigen may have been deposited previously - immune complexes are formed during many immune responses and represent a normal mechanism of antigen removal; some are just pathogenic - two types of antigens cause immune ...
DEFINITIONS - Tehran University of Medical Sciences
DEFINITIONS - Tehran University of Medical Sciences

... contiguous sequence of amino acids)  non-contiguous (when Ab binds to non-contiguous residues, brought together by folding).  Sequential epitopes are contiguous epitopes.  Conformational epitopes are noncontiguous antigenic determinants. ...
Slide 1
Slide 1

... Form large antigen binding pocket for peptide presentation by APCs ...
Answers to WHAT DID YOU LEARN QUESTIONS
Answers to WHAT DID YOU LEARN QUESTIONS

... T-lymphocyte types include helper T-lymphocytes that initiate and oversee the immune response, cytotoxic T-lymphocytes that kill by secreting substances into foreign or abnormal cells, memory T-lymphocytes that mount an even faster immune response at the next encounter with the antigen, and suppress ...
MICR 201 Microbiology for Health Related Sciences
MICR 201 Microbiology for Health Related Sciences

... 13) What type of vaccine involves host synthesis of viral antigens? A) Conjugated vaccine B) Subunit vaccine C) Nucleic acid vaccine D) Attenuated whole-agent vaccine E) Toxoid vaccine ...
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Duffy antigen system

Duffy antigen/chemokine receptor (DARC) also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234) is a protein that in humans is encoded by the DARC gene.The Duffy antigen is located on the surface of red blood cells, and is named after the patient in which it was discovered. The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The protein is also the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system.
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