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Introduction to Blood
Introduction to Blood

... - First contact between a CTL or NK cell with infected cells is via non-specific binding of adhesion molecules (LFA-1 (blue) on T and NK cells with ICAM-1 or ICAM-2 (brown) on target cells). This makes a channel between the target and the cytotoxic cell. - Specific antigen/MHC class I recognition by ...
What is the Immune System
What is the Immune System

... target cell quickly, by the injection of deadly perforin. (Courtesy of Dr. G. Arancia and K. Malorni, Rome) ...
AQA Immunity Booklet Answers
AQA Immunity Booklet Answers

... response occurs. Memory cells are made during this process which remain dormant in the body, ready to divide rapidly when they come into contact with the same antigen. ...
Agglutination - WordPress.com
Agglutination - WordPress.com

...  RIA works on the principle of competitive binding.  In this method, unlabeled antigen competes with radiolabelled antigen for binding to the antibody.  When mixtures of radiolabeled and unlabeled antigen are incubated with the corresponding antibody, the amount of free radiolabeled antigen is di ...
Slide 1
Slide 1

... and are more flexible than the rest of the ...
The importance of the immune system
The importance of the immune system

... Chemokines also promote cell adhesion to endothelium Lymphoid chemokines – help direct the homeostatic trafficking of cells through lymphoid tissues (e.g. CCR7 / CCL21; CXCR5 / CXCL13) Inflammatory chemokines – induced at sites of inflammation; can be expressed by many cell types; help recruit cells ...
11.1 HL Immune System Part 1
11.1 HL Immune System Part 1

... • There are genes on our 6th chromosome that code for our MHC. Thus, our MHC is genetically determined. • Each of us as a unique MHC on our cells membrane. ...
document
document

... Yellow both systems intact ...
Name - Medical Mastermind Community
Name - Medical Mastermind Community

... 57. By standard criteria set by the Centers for Disease Control and Prevention, an HIV-infected patient who has a CD4+ T cell count of 180 per microliter of blood but no known opportunistic infections would be characterized as having: A. Late symptomatic Infection (AIDS). B. Early symptomatic infect ...
B cell
B cell

... Important cells involved are T lymphocytes and B lymphocytes These cells are responsible for specific immune responses to specific pathogens ...
Principles of Innate and Adaptive Immunity - Abdel
Principles of Innate and Adaptive Immunity - Abdel

... those antigens that are not “self” and to avoid making responses to those antigens that are part of “self”. The most widely accepted theory that best explains these features is the clonal selection theory. The essential features of the clonal selection theory may be summarized as follows: 1- B and T ...
elisa
elisa

... and fully half the population was tuberculin-positive, it was well-known that an intercurrent measles infection would cause a well-contained tuberculosis infection to run rampant and result in death. The mechanism responsible is now known to be the supression of IL-2 synthesis after binding of measl ...
A1982PC81600001
A1982PC81600001

... that the spleen has all the necessary immunologic machinery), but transferred thymus cells plus antigen were inert. “The important experiment involved pure serendipity. We felt that the transferred thymus cells might be either too immature or too ‘sluggish’ to respond, so we gave the recipients thym ...
the immune system phagocytosis antibody function
the immune system phagocytosis antibody function

...  Artificial Passive Immunity: occurs as a result of ...
BIOLOGY PRESENTATION
BIOLOGY PRESENTATION

... When it comes to fetal maternal relationships the first question that comes in people’s mind is how does the fetus do to nestle in the uterus and not to be rejected? Because it’s semi allogeneic meaning it has not only antigens from the mother but also antigens from the father which are foreign. It ...
elisa - immunology.unideb.hu
elisa - immunology.unideb.hu

... and fully half the population was tuberculin-positive, it was well-known that an intercurrent measles infection would cause a well-contained tuberculosis infection to run rampant and result in death. The mechanism responsible is now known to be the supression of IL-2 synthesis after binding of measl ...
Aseptic Technique: Media and Equipment
Aseptic Technique: Media and Equipment

... – knew there were certain proteins in blood involved (Bence Jones proteins) ...
No Slide Title
No Slide Title

... two different ways, RNA splicing and DNA switch recombination. The signals regulating these changes come from antigen binding to the B cell receptor and antigen specific T cells. During the immune response B cells mutate their immunoglobulin variable regions under the control of T cells and other si ...
Type II hypersensitivity
Type II hypersensitivity

... Type II hypersensitivity: Ab – mediated, Generally cytotoxic – Tissue specific. ...
Immune System
Immune System

...  Acquired/Adaptive response = slower response to specific microbes; develops over time due to exposure. - Only found in vertebrates  Antigen = protein or glycoprotein on cell surface of “invader” that stimulates a response by the immune system via leukocytes (WBC) o Epitope = specific area on anti ...
Micro 532 Exam 1995
Micro 532 Exam 1995

... Contact dermatitis generally occurs against substances that are too small to induce an immune response. How do these substance induce an immune response? a. b. ...
Chapter 4. Antigens
Chapter 4. Antigens

... Generated by variation in amino acid sequence in the VH and VL. Most exactly, in the CDRs in the V regions ...
B cells
B cells

...  Age group Young children : Polio, smallpox, measles, cough  Occupation Medical workers: Hepatitis B Sewage workers, field workers: Plague  Traveller ...
Chapter 43 Immune System
Chapter 43 Immune System

... cellular and chemical defenses take over • White blood cells that serve as phagocytes that engulf and destroy microbes - also initiate the inflammatory response Four types of phagocytic WBC: 1. Neutrophils – most abundant; life span a few days 2. Macrophages – larger, longer living WBC, but only 5% ...
ag-ab react
ag-ab react

... Immunofluorescence is an antigen-antibody reaction where the Abs are tagged (labelled) with a fluorescent dye and the antigen-antibody complex is ...
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Duffy antigen system

Duffy antigen/chemokine receptor (DARC) also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234) is a protein that in humans is encoded by the DARC gene.The Duffy antigen is located on the surface of red blood cells, and is named after the patient in which it was discovered. The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The protein is also the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system.
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