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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 11. _______ is added in the HAT medium to block dihydrofolate reductase. 12. Immunoproteasomes generate peptides that can bind with MHC class _____ molecules. 13. ________ graft rejection occurs months or years after transplantation. 14. ________ bind to antibodies but do not induce an immune respon ...
File - Science at St. Dominics
File - Science at St. Dominics

...  This involves an antigen-antibody response, and uses specialised white blood cells, called lymphocytes and monocytes both made in the bone marrow. ...
cell - immunology.unideb.hu
cell - immunology.unideb.hu

... Antibodies are natural products that appear on the cell surface as receptors and selectively react with the antigen Lymphocyte receptors are variable and carry various antigen-recognizing receptors ‘Non-self’ antigens/pathogens encounter the existing lymphocyte pool (repertoire) Antigens select thei ...
antigen-antibody reaction
antigen-antibody reaction

... In some cases two antigens may be bridged by a single antibody. Such a binding is weak. But when two antigens are bridge by two antibodies, the binding will be strong. This phenomenon of giving extra- strength to the antigen-antibody complex by the binding of two antibodies to two antigen molecules ...
MORPHOLOGIE DES HEMATIES Normales et Pathologiques
MORPHOLOGIE DES HEMATIES Normales et Pathologiques

... Capsules, cell walls, toxins, viral capsids, flagella, etc.  Non-microbes: Pollen, egg white, red blood cell surface molecules, serum proteins, and surface molecules from transplanted tissue.  Lipids and nucleic acids are only antigenic when combined with proteins or polysaccharides.  Molecular w ...
ELISA technique
ELISA technique

... isolated from the animal and immortalized by fusing them with a cancer cell line. The fused cells are called hybridomas, and will continually grow and secrete antibody in culture. Single hybridoma cells are isolated by dilution cloning to generate cell clones that all produce the same antibody; thes ...
Veterinary Immunology
Veterinary Immunology

... • Named because it was discovered that protection from certain diseases could be accomplished  by transfer of body "humors" (fluids)  • Antibody and B (B = Bursa of Fabricius) lymphocytes are important in humoral immunity  • Immunoglobulin = antibody = Ig = Ab = Y  • Classes (Isotypes) of Antibody – ...
Symbiosis and Host Defenses
Symbiosis and Host Defenses

... immunological functions from cell surface receptors to circulation, or excretion • The sections of DNA that encode the part the antibody that binds to antigen is highly variable allowing the formation of millions of different antigens so antibodies may be formed to any foreign molecule that is compl ...
Fall 2004 - Antelope Valley College
Fall 2004 - Antelope Valley College

... _________________ ________________ is the selection process which destroys immune cells that could attack our own tissues. ...
ANTI-H LECTIN
ANTI-H LECTIN

... The H antigen is a basic blood group antigen present in human beings. There is considerable variation in the H antigen content in different individuals of the same ABO group but the general pattern indicates their strength as O>A2>A2B>B>A1>A1B. Water soluble H substance can also be demonstrated in s ...
File
File

... bind to specific antigens, thus a lymphocyte with a complementary antibody must come into contact with the antigen before an immune response happens The complementary ‘arm’ of the antibody binds to an antigen on the surface of a pathogen. Antibodies coat the pathogen, directly killing it or ‘tag’ it ...
Blood Group Antigens and Antibodies III
Blood Group Antigens and Antibodies III

... clinically significant • Rare examples of hemolytic anti-Lea and even rarer examples of anti-Leb have been found • Mostly not necessary to type donor blood Lewis antigens prior to transfusion or crossmatching – Reactions obtained in the crossmatch provide a good index of transfusion safety – If aggl ...
1) if the response to an antigen
1) if the response to an antigen

... infectious agents. The disease may be X-linked (in boys only) or autosomal ( inherited in girls also). Causes: i- aplasia of B. M. or Failure of lymphocyte development and maturation in which both T-cells and B cells (if present) are not functional. ii- genetic disorder of purine metabolism: genetic ...
Understanding the Immune System
Understanding the Immune System

... Lymphocytes which react with high affinity to this self-antigen are deleted (apoptosis) Lymphocytes which react with low affinity are positively selected to mature ...
BIOL 495: Introduction to Immunology
BIOL 495: Introduction to Immunology

... *Protective adaptations in higher organisms to rid the body of foreign particles (microbial and otherwise) and abnormal cells Our Immune system involves the interplay between our Non-specific and our Specific Immune responses Non-specific immunities collectively referred to as our Innate immunity ...
biology 37.2
biology 37.2

... phagocytosis by helping the phagocytic cells bind better to pathogens, activating the phagocytes and enhancing the destruction of the pathogen’s membrane, . . . (p. 1085) Virus-infected cells secrete a protein called interferon. (p. 1085) ...
2.-B-and-T-lymphocytes
2.-B-and-T-lymphocytes

... The binding of the antibodies causes the • inactivation of the pathogen (or the toxin it produces) and • pathogen to become more susceptible to ...
432W9EX1
432W9EX1

... Each description may be used once, more than once, or not at all; more than one description may apply to some isotypes. IgA: IgD: IgE: IgG: ...
The humoral immune response defends against pathogens that are
The humoral immune response defends against pathogens that are

... different particles containing antigenic sites, clumping them all together and preventing their proper functioning . Antibody neutralization can prevent pathogens from entering and infecting host cells. The neutralized antibody-coated pathogens can then be filtered by the spleen to be eliminated in ...
acquired immunity
acquired immunity

... A. Blood-borne antigens – spleen . B. Skin & tissues – draining lymph nodes. ...
IN RESPONSE TO DAMAGE Innate, or nonspecific, immunity
IN RESPONSE TO DAMAGE Innate, or nonspecific, immunity

... During the humoral immune response, IgM is the first class of antibody made. After several days, other classes appear. Exactly which other Ig classes a B cell makes depends on the kind of interleukins it receives from the T helper cells. Antibodies can sometimes stop an antigen’s disease-causing ac ...
Immunity and Immune Response
Immunity and Immune Response

... Cell Mediated Immune System: T lymphocytes • T-cells mature in the thymus (thus the name T-cell) • Act on antigens appearing on the surface of individual cells. • Over a million different kinds of T-cells – Each produces a different receptor in the cell membrane – Each receptor is composed of 1 mol ...
Immunology Review
Immunology Review

... Interleukin-1: cytokines produced by macrophages which activate nearby vascular endothelium to promote leukocyte movement into the tissue (extravasation) Interlukin – 8: chemokines which recruit leukocytes and attract them to site of infection L-selectin: neutrophil-adhesion molecule that initiates ...
Immune System
Immune System

... Naturally Acquired Active Immunity: resistance to a specific disease after the development of antibodies during the actual disease Artificially Acquired Passive Immunity: resistance to a specific disease by receiving antiserum-containing antibodies from another host ...
antigen presentation clonal selection induction of antibody synthesis
antigen presentation clonal selection induction of antibody synthesis

... surface. The MHCII-peptide complex is recognized by a specific T cell receptor (of which there are many). Binding is facilitated by the surface protein CD4 ( the HIV receptor). The macrophage secretes a chemical messenger called interleukin 1 which stimulates the T cell to divide and form two popula ...
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Duffy antigen system

Duffy antigen/chemokine receptor (DARC) also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234) is a protein that in humans is encoded by the DARC gene.The Duffy antigen is located on the surface of red blood cells, and is named after the patient in which it was discovered. The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The protein is also the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system.
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